Class information for: |
Basic class information |
Class id | #P | Avg. number of references |
Database coverage of references |
---|---|---|---|
5307 | 1643 | 44.0 | 91% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
Cluster id | Level | Cluster label | #P |
---|---|---|---|
0 | 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY | 4064930 |
204 | 3 | PROTEASOME//UBIQUITIN//UNFOLDED PROTEIN RESPONSE | 52492 |
1195 | 2 | JNK//ERK5//MAP KINASE | 9252 |
5307 | 1 | MK2//P38 INHIBITORS//P38 ALPHA | 1643 |
Terms with highest relevance score |
rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|---|
1 | MK2 | authKW | 547308 | 3% | 63% | 47 |
2 | P38 INHIBITORS | authKW | 292678 | 1% | 75% | 21 |
3 | P38 ALPHA | authKW | 211148 | 2% | 45% | 25 |
4 | P38 | authKW | 202773 | 8% | 8% | 136 |
5 | MAPKAPK2 | authKW | 199864 | 1% | 51% | 21 |
6 | MK5 | authKW | 185834 | 1% | 100% | 10 |
7 | P38 MAP KINASE | authKW | 183494 | 4% | 15% | 68 |
8 | P38 GAMMA | authKW | 154858 | 1% | 83% | 10 |
9 | P38 MAPK | authKW | 154541 | 7% | 7% | 121 |
10 | ERK3 | authKW | 132733 | 1% | 71% | 10 |
Web of Science journal categories |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | Chemistry, Medicinal | 7681 | 21% | 0% | 339 |
2 | Biochemistry & Molecular Biology | 2360 | 34% | 0% | 553 |
3 | Cell Biology | 1882 | 19% | 0% | 308 |
4 | Chemistry, Organic | 725 | 11% | 0% | 180 |
5 | Pharmacology & Pharmacy | 523 | 13% | 0% | 210 |
6 | Immunology | 375 | 9% | 0% | 148 |
7 | Biophysics | 235 | 5% | 0% | 89 |
8 | Rheumatology | 115 | 2% | 0% | 30 |
9 | Oncology | 95 | 6% | 0% | 101 |
10 | Crystallography | 56 | 2% | 0% | 37 |
Address terms |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | ANTIBIOT BIOARCHITECT GRP | 92917 | 0% | 100% | 5 |
2 | SHOCK MICROCIRCULAT PLA | 38710 | 0% | 42% | 5 |
3 | SIGNAL DEPENDENT TRANSCRIPT | 38710 | 0% | 42% | 5 |
4 | PHARMACEUT MED CHEM | 37639 | 4% | 4% | 58 |
5 | ALMIRALL S | 37167 | 0% | 100% | 2 |
6 | CARDIOVASC UROGENITARY ONCOL EXCELLENCE DRU | 37167 | 0% | 100% | 2 |
7 | DENT UNIT ORAL MICROBIOL | 37167 | 0% | 100% | 2 |
8 | PHARMCOKINET DRUG METAB | 37167 | 0% | 100% | 2 |
9 | PROTE GONGDONG PROV | 37167 | 0% | 100% | 2 |
10 | CANC OSTEOPOROSIS | 37163 | 0% | 50% | 4 |
Journals |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 13339 | 8% | 1% | 135 |
2 | JOURNAL OF MEDICINAL CHEMISTRY | 3682 | 4% | 0% | 66 |
3 | EXPERT OPINION ON THERAPEUTIC PATENTS | 3648 | 1% | 1% | 21 |
4 | CURRENT TOPICS IN MEDICINAL CHEMISTRY | 1363 | 1% | 1% | 13 |
5 | JOURNAL OF BIOLOGICAL CHEMISTRY | 1280 | 7% | 0% | 108 |
6 | GAS ENGINEERING & MANAGEMENT | 1237 | 0% | 7% | 1 |
7 | MOLECULAR AND CELLULAR BIOLOGY | 802 | 2% | 0% | 32 |
8 | CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT | 741 | 0% | 1% | 5 |
9 | CELLULAR SIGNALLING | 698 | 1% | 0% | 13 |
10 | MEDCHEMCOMM | 662 | 0% | 1% | 7 |
Author Key Words |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | MK2 | 547308 | 3% | 63% | 47 | Search MK2 | Search MK2 |
2 | P38 INHIBITORS | 292678 | 1% | 75% | 21 | Search P38+INHIBITORS | Search P38+INHIBITORS |
3 | P38 ALPHA | 211148 | 2% | 45% | 25 | Search P38+ALPHA | Search P38+ALPHA |
4 | P38 | 202773 | 8% | 8% | 136 | Search P38 | Search P38 |
5 | MAPKAPK2 | 199864 | 1% | 51% | 21 | Search MAPKAPK2 | Search MAPKAPK2 |
6 | MK5 | 185834 | 1% | 100% | 10 | Search MK5 | Search MK5 |
7 | P38 MAP KINASE | 183494 | 4% | 15% | 68 | Search P38+MAP+KINASE | Search P38+MAP+KINASE |
8 | P38 GAMMA | 154858 | 1% | 83% | 10 | Search P38+GAMMA | Search P38+GAMMA |
9 | P38 MAPK | 154541 | 7% | 7% | 121 | Search P38+MAPK | Search P38+MAPK |
10 | ERK3 | 132733 | 1% | 71% | 10 | Search ERK3 | Search ERK3 |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
---|---|---|---|---|
1 | GANGWAL, RP , BHADAURIYA, A , DAMRE, MV , DHOKE, GV , SANGAMWAR, AT , (2013) P38 MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORS: A REVIEW ON PHARMACOPHORE MAPPING AND QSAR STUDIES.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 9. P. 1015 -1035 | 122 | 85% | 5 |
2 | FIORE, M , FORLI, S , MANETTI, F , (2016) TARGETING MITOGEN-ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE 2 (MAPKAPK2, MK2): MEDICINAL CHEMISTRY EFFORTS TO LEAD SMALL MOLECULE INHIBITORS TO CLINICAL TRIALS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 59. ISSUE 8. P. 3609 -3634 | 66 | 75% | 3 |
3 | AMIR, M , SOMAKALA, K , ALI, S , (2013) P38 MAP KINASE INHIBITORS AS ANTI INFLAMMATORY AGENTS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 14. P. 2082-2096 | 66 | 89% | 12 |
4 | CUADRADO, A , NEBREDA, AR , (2010) MECHANISMS AND FUNCTIONS OF P38 MAPK SIGNALLING.BIOCHEMICAL JOURNAL. VOL. 429. ISSUE . P. 403 -417 | 72 | 44% | 408 |
5 | ASTOLFI, A , IRACI, N , MANFRONI, G , BARRECA, ML , CECCHETTI, V , (2015) A COMPREHENSIVE STRUCTURAL OVERVIEW OF P38 MAPK IN COMPLEX WITH TYPEI INHIBITORS.CHEMMEDCHEM. VOL. 10. ISSUE 6. P. 957 -969 | 65 | 79% | 1 |
6 | GUPTA, J , NEBREDA, AR , (2015) ROLES OF P38 ALPHA MITOGEN-ACTIVATED PROTEIN KINASE IN MOUSE MODELS OF INFLAMMATORY DISEASES AND CANCER.FEBS JOURNAL. VOL. 282. ISSUE 10. P. 1841 -1857 | 72 | 63% | 9 |
7 | PEIFER, C , WAGNER, G , LAUFER, S , (2006) NEW APPROACHES TO THE TREATMENT OF INFLAMMATORY DISORDERS SMALL MOLECULE INHIBITORS OF P38 MAP KINASE.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 6. ISSUE 2. P. 113-149 | 62 | 84% | 100 |
8 | FISCHER, S , KOEBERLE, SC , LAUFER, SA , (2011) P38 ALPHA MITOGEN-ACTIVATED PROTEIN KINASE INHIBITORS, A PATENT REVIEW (2005-2011).EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 21. ISSUE 12. P. 1843 -1866 | 54 | 90% | 15 |
9 | SCIOR, T , DOMEYER, DM , CUANALO-CONTRERAS, K , LAUFER, SA , (2011) PHARMACOPHORE DESIGN OF P38 ALPHA MAP KINASE INHIBITORS WITH EITHER 2,4,5-TRISUBSTITUTED OR 1,2,4,5-TETRASUBSTITUTED IMIDAZOLE SCAFFOLD.CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 10. P. 1526 -1539 | 72 | 68% | 8 |
10 | KUMAR, S , BOEHM, J , LEE, JC , (2003) P38 MAP KINASES: KEY SIGNALLING MOLECULES AS THERAPEUTIC TARGETS FOR INFLAMMATORY DISEASES.NATURE REVIEWS DRUG DISCOVERY. VOL. 2. ISSUE 9. P. 717-726 | 46 | 70% | 735 |
Classes with closest relation at Level 1 |