Class information for:
Level 1: BRCA1//BARD1//BRCA2

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5107 1672 46.5 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
512 3       BRCA1//BRCA2//FANCONI ANEMIA 21435
900 2             BRCA1//BRCA2//FANCONI ANEMIA 11301
5107 1                   BRCA1//BARD1//BRCA2 1672

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BRCA1 authKW 2087288 32% 21% 542
2 BARD1 authKW 730729 3% 82% 49
3 BRCA2 authKW 502218 12% 14% 201
4 BRCT authKW 217634 1% 57% 21
5 MOL GYNECOL OBSTET address 154297 1% 65% 13
6 BCCIP authKW 140465 1% 77% 10
7 BRCA1 PROMOTER authKW 99418 0% 78% 7
8 SPORADIC BREAST CANCER authKW 91641 1% 31% 16
9 BRCT DOMAIN authKW 85578 1% 31% 15
10 RAD51 authKW 84660 3% 10% 47

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 13391 46% 0% 776
2 Cell Biology 6037 31% 0% 526
3 Genetics & Heredity 4528 22% 0% 375
4 Biochemistry & Molecular Biology 3584 40% 0% 667
5 Biophysics 172 5% 0% 80
6 Toxicology 80 3% 0% 48
7 Developmental Biology 69 2% 0% 28
8 Pathology 42 2% 0% 36
9 Medicine, Research & Experimental 23 3% 0% 44
10 Biology 12 1% 0% 25

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL GYNECOL OBSTET 154297 1% 65% 13
2 HISTOL EMBRYOL BASIC MED SCI 73044 0% 100% 4
3 GENET DEV DIS BRANCH 57932 2% 9% 34
4 HEARST MICROBIOL 40663 0% 32% 7
5 GEORGIA CANC EXCELLENCE 38038 0% 42% 5
6 GENOME TECHNOL INTEGRAT SYST BIOL 36522 0% 100% 2
7 OB GYNCANC BIOL PROGRAM 36522 0% 100% 2
8 PATHOL CELL BIOL CANC GENET 36522 0% 100% 2
9 SEZ GENET ONCOL 36522 0% 100% 2
10 STRONG CANC 36522 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENE 18074 8% 1% 134
2 BREAST CANCER RESEARCH 5643 2% 1% 26
3 BREAST CANCER RESEARCH AND TREATMENT 5045 3% 1% 45
4 CANCER RESEARCH 4562 6% 0% 100
5 DNA REPAIR 3208 1% 1% 19
6 CANCER BIOLOGY & THERAPY 1852 1% 1% 17
7 GENES CHROMOSOMES & CANCER 1448 1% 1% 16
8 JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA 1446 0% 1% 7
9 CELL CYCLE 1348 0% 1% 7
10 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 1169 1% 0% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BRCA1 2087288 32% 21% 542 Search BRCA1 Search BRCA1
2 BARD1 730729 3% 82% 49 Search BARD1 Search BARD1
3 BRCA2 502218 12% 14% 201 Search BRCA2 Search BRCA2
4 BRCT 217634 1% 57% 21 Search BRCT Search BRCT
5 BCCIP 140465 1% 77% 10 Search BCCIP Search BCCIP
6 BRCA1 PROMOTER 99418 0% 78% 7 Search BRCA1+PROMOTER Search BRCA1+PROMOTER
7 SPORADIC BREAST CANCER 91641 1% 31% 16 Search SPORADIC+BREAST+CANCER Search SPORADIC+BREAST+CANCER
8 BRCT DOMAIN 85578 1% 31% 15 Search BRCT+DOMAIN Search BRCT+DOMAIN
9 RAD51 84660 3% 10% 47 Search RAD51 Search RAD51
10 BRCA1 PROTEIN 82166 1% 50% 9 Search BRCA1+PROTEIN Search BRCA1+PROTEIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 IRMINGER-FINGER, I , RATAJSKA, M , PILYUGIN, M , (2016) NEW CONCEPTS ON BARD1: REGULATOR OF BRCA PATHWAYS AND BEYOND.INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. VOL. 72. ISSUE . P. 1 -17 111 74% 0
2 GUDMUNDSDOTTIR, K , ASHWORTH, A , (2006) THE ROLES OF BRCA1 AND BRCA2 AND ASSOCIATED PROTEINS IN THE MAINTENANCE OF GENOMIC STABILITY.ONCOGENE. VOL. 25. ISSUE 43. P. 5864 -5874 86 75% 252
3 ROSEN, EM , FAN, SJ , PESTELL, RG , GOLDBERG, ID , (2003) BRCA1 GENE IN BREAST CANCER.JOURNAL OF CELLULAR PHYSIOLOGY. VOL. 196. ISSUE 1. P. 19-41 151 56% 113
4 ROY, R , CHUN, J , POWELL, SN , (2012) BRCA1 AND BRCA2: DIFFERENT ROLES IN A COMMON PATHWAY OF GENOME PROTECTION.NATURE REVIEWS CANCER. VOL. 12. ISSUE 1. P. 68 -78 64 59% 258
5 PAUL, A , PAUL, S , (2014) THE BREAST CANCER SUSCEPTIBILITY GENES (BRCA) IN BREAST AND OVARIAN CANCERS.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 19. ISSUE . P. 605-618 102 55% 15
6 JASIN, M , (2002) HOMOLOGOUS REPAIR OF DNA DAMAGE AND TUMORIGENESIS: THE BRCA CONNECTION.ONCOGENE. VOL. 21. ISSUE 58. P. 8981-8993 85 73% 209
7 VENKITARAMAN, AR , (2002) CANCER SUSCEPTIBILITY AND THE FUNCTIONS OF BRCA1 AND BRCA2.CELL. VOL. 108. ISSUE 2. P. 171-182 52 72% 965
8 MULLAN, PB , QUINN, JE , HARKIN, DP , (2006) THE ROLE OF BRCA1 IN TRANSCRIPTIONAL REGULATION AND CELL CYCLE CONTROL.ONCOGENE. VOL. 25. ISSUE 43. P. 5854-5863 66 76% 125
9 EVERS, B , JONKERS, J , (2006) MOUSE MODELS OF BRCA1 AND BRCA2 DEFICIENCY: PAST LESSONS, CURRENT UNDERSTANDING AND FUTURE PROSPECTS.ONCOGENE. VOL. 25. ISSUE 43. P. 5885-5897 77 67% 98
10 MILLOT, GA , CARVALHO, MA , CAPUTO, SM , VREESWIJK, MPG , BROWN, MA , WEBB, M , ROULEAU, E , NEUHAUSEN, SL , HANSEN, TVO , GALLI, A , ET AL (2012) A GUIDE FOR FUNCTIONAL ANALYSIS OF BRCA1 VARIANTS OF UNCERTAIN SIGNIFICANCE.HUMAN MUTATION. VOL. 33. ISSUE 11. P. 1526 -1537 73 60% 29

Classes with closest relation at Level 1


Rank Class id link
1 471 BRCA2//BRCA1//HEREDITARY BREAST CANCER
2 10345 PARP INHIBITORS//OLAPARIB//SYNTHETIC LETHALITY
3 15199 CHEK2//PALB2//CHK2
4 3535 NIJMEGEN BREAKAGE SYNDROME//NBS1//MRE11
5 4671 RAD51//RAD52//HOMOLOGOUS RECOMBINATION
6 29487 PINK EYED UNSTABLE//RADIAT ON AB MOL CELLULAR RADIAT BIOL//3 5 EXONUCLEASE
7 14360 GSTP1//UNIDAD DOCENTE BIOQUIM BIOL MOL//DNA METHYLATION
8 3284 FANCONI ANEMIA//FANCONI ANAEMIA//FANCD2
9 12433 EI24//CLIN BREAST CARE PROJECT//LOSS OF HETEROZYGOSITY
10 27586 BAP1//SETD2//BRCA1 ASSOCIATED PROTEIN 1

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