Class information for:
Level 3: BRCA1//BRCA2//FANCONI ANEMIA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
512 21435 38.4 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
512 3       BRCA1//BRCA2//FANCONI ANEMIA 21435
900 2             BRCA1//BRCA2//FANCONI ANEMIA 11301
1039 2             GENETIC TESTING//BIOBANK//JOURNAL OF GENETIC COUNSELING 10134

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 BRCA1 authKW 1652352 8% 67% 1728
2 BRCA2 authKW 1236871 5% 77% 1130
3 FANCONI ANEMIA authKW 573506 2% 77% 526
4 GENETIC TESTING authKW 554325 4% 42% 920
5 GENETIC COUNSELING authKW 276921 3% 35% 563
6 BIOBANK authKW 269264 2% 53% 355
7 JOURNAL OF GENETIC COUNSELING journal 229103 2% 49% 327
8 BRCA authKW 227700 1% 58% 275
9 GENETICS IN MEDICINE journal 207165 2% 30% 485
10 HEREDITARY BREAST CANCER authKW 202649 1% 76% 188

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Genetics & Heredity 80803 26% 1% 5610
2 Oncology 67700 30% 1% 6440
3 Medical Ethics 36851 3% 5% 552
4 Ethics 15242 3% 2% 624
5 Social Sciences, Biomedical 14609 4% 1% 775
6 Public, Environmental & Occupational Health 4007 7% 0% 1486
7 Social Issues 3709 1% 1% 307
8 Cell Biology 2546 8% 0% 1635
9 Medical Laboratory Technology 1661 2% 0% 368
10 Medicine, General & Internal 1478 6% 0% 1197

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC GENET EPIDEMIOL 132187 1% 54% 172
2 FAMILY CANC CLIN 123817 1% 62% 140
3 GENOM POLICY 116793 1% 74% 111
4 INT HEREDITARY CANC 87040 1% 49% 125
5 UNIT MOL BASES GENET RISK GENET TESTING 75939 0% 69% 77
6 CLIN CANC GENET 74237 0% 49% 106
7 CLIN GENET 72709 3% 7% 721
8 CLIN GENET HUMAN GENET 64745 0% 56% 81
9 SOCIAL BEHAV BRANCH 62928 0% 46% 96
10 PROGRAM CANC GENET 59848 0% 42% 101

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF GENETIC COUNSELING 229103 2% 49% 327
2 GENETICS IN MEDICINE 207165 2% 30% 485
3 FAMILIAL CANCER 143183 1% 34% 297
4 PUBLIC HEALTH GENOMICS 141341 1% 55% 182
5 PERSONALIZED MEDICINE 124245 1% 40% 218
6 BIOPRESERVATION AND BIOBANKING 99443 1% 45% 157
7 HEREDITARY CANCER IN CLINICAL PRACTICE 43879 0% 41% 75
8 BREAST CANCER RESEARCH AND TREATMENT 42021 2% 6% 466
9 GENETIC TESTING 37759 1% 20% 131
10 EUROPEAN JOURNAL OF HUMAN GENETICS 32337 1% 8% 290

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 BRCA1 1652352 8% 67% 1728 Search BRCA1 Search BRCA1
2 BRCA2 1236871 5% 77% 1130 Search BRCA2 Search BRCA2
3 FANCONI ANEMIA 573506 2% 77% 526 Search FANCONI+ANEMIA Search FANCONI+ANEMIA
4 GENETIC TESTING 554325 4% 42% 920 Search GENETIC+TESTING Search GENETIC+TESTING
5 GENETIC COUNSELING 276921 3% 35% 563 Search GENETIC+COUNSELING Search GENETIC+COUNSELING
6 BIOBANK 269264 2% 53% 355 Search BIOBANK Search BIOBANK
7 BRCA 227700 1% 58% 275 Search BRCA Search BRCA
8 HEREDITARY BREAST CANCER 202649 1% 76% 188 Search HEREDITARY+BREAST+CANCER Search HEREDITARY+BREAST+CANCER
9 PARP INHIBITORS 151504 1% 57% 187 Search PARP+INHIBITORS Search PARP+INHIBITORS
10 BRCA1 2 130794 1% 67% 137 Search BRCA1+2 Search BRCA1+2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KARAMI, F , MEHDIPOUR, P , (2013) A COMPREHENSIVE FOCUS ON GLOBAL SPECTRUM OF BRCA1 AND BRCA2 MUTATIONS IN BREAST CANCER.BIOMED RESEARCH INTERNATIONAL. VOL. . ISSUE . P. - 166 94% 14
2 MOLDOVAN, GL , D'ANDREA, AD , (2009) HOW THE FANCONI ANEMIA PATHWAY GUARDS THE GENOME.ANNUAL REVIEW OF GENETICS. VOL. 43. ISSUE . P. 223-249 128 83% 272
3 THOMPSON, LH , HINZ, JM , (2009) CELLULAR AND MOLECULAR CONSEQUENCES OF DEFECTIVE FANCONI ANEMIA PROTEINS IN REPLICATION-COUPLED DNA REPAIR: MECHANISTIC INSIGHTS.MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. VOL. 668. ISSUE 1-2. P. 54 -72 186 72% 94
4 PAUL, A , PAUL, S , (2014) THE BREAST CANCER SUSCEPTIBILITY GENES (BRCA) IN BREAST AND OVARIAN CANCERS.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 19. ISSUE . P. 605-618 153 83% 15
5 PRAKASH, R , ZHANG, Y , FENG, WR , JASIN, M , (2015) HOMOLOGOUS RECOMBINATION AND HUMAN HEALTH: THE ROLES OF BRCA1, BRCA2, AND ASSOCIATED PROTEINS.COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. VOL. 7. ISSUE 4. P. - 143 53% 53
6 NAROD, SA , FOULKES, WD , (2004) BRCA1 AND BRCA2: 1994 AND BEYOND.NATURE REVIEWS CANCER. VOL. 4. ISSUE 9. P. 665-676 131 81% 455
7 CECCALDI, R , SARANGI, P , D'ANDREA, AD , (2016) THE FANCONI ANAEMIA PATHWAY: NEWYPLAYERS AND NEW FUNCTIONS.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 17. ISSUE 6. P. 337 -349 99 73% 11
8 LYNCH, HT , KOSOKO-LASAKI, O , LESLIE, SW , RENDELL, M , SHAW, T , SNYDER, C , D'AMICO, AV , BUXBAUM, S , ISAACS, WB , LOEB, S , ET AL (2016) SCREENING FOR FAMILIAL AND HEREDITARY PROSTATE CANCER.INTERNATIONAL JOURNAL OF CANCER. VOL. 138. ISSUE 11. P. 2579 -2591 116 85% 3
9 YUAN, FH , SONG, LM , QIAN, LY , HU, JJ , ZHANG, YB , (2010) ASSEMBLING AN ORCHESTRA: FANCONI ANEMIA PATHWAY OF DNA REPAIR.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 15. ISSUE . P. 1131-1149 172 79% 3
10 GUIDUGLI, L , CARREIRA, A , CAPUTO, SM , EHLEN, A , GALLI, A , MONTEIRO, ANA , NEUHAUSEN, SL , HANSEN, TVO , COUCH, FJ , VREESWIJK, MPG , (2014) FUNCTIONAL ASSAYS FOR ANALYSIS OF VARIANTS OF UNCERTAIN SIGNIFICANCE IN BRCA2.HUMAN MUTATION. VOL. 35. ISSUE 2. P. 151 -164 118 92% 12

Classes with closest relation at Level 3


Rank Class id link
1 447 TCTP//TRANSLATIONALLY CONTROLLED TUMOR PROTEIN//GENETIC EPIDEMIOLOGY
2 499 MEDICAL ETHICS//INFORMED CONSENT//ETHICS
3 142 DNA REPAIR//INTERNATIONAL JOURNAL OF RADIATION BIOLOGY//RADIATION RESEARCH
4 109 RECTAL CANCER//COLORECTAL CANCER//COLONOSCOPY
5 304 P53//RETINOBLASTOMA//MDM2
6 603 HUNTINGTONS DISEASE//SPINOCEREBELLAR ATAXIA//POLYGLUTAMINE
7 296 BREAST//BREAST CANCER//LYMPHEDEMA
8 159 MENOPAUSE//ISOFLAVONES//TAMOXIFEN
9 90 MATHEMATICAL & COMPUTATIONAL BIOLOGY//BIOINFORMATICS//BMC BIOINFORMATICS
10 364 TELOMERASE//TELOMERE//C ELEGANS

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