Class information for:
Level 1: BRCA2//BRCA1//HEREDITARY BREAST CANCER

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
471 3398 36.0 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
512 3       BRCA1//BRCA2//FANCONI ANEMIA 21435
900 2             BRCA1//BRCA2//FANCONI ANEMIA 11301
471 1                   BRCA2//BRCA1//HEREDITARY BREAST CANCER 3398

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BRCA2 authKW 3049781 21% 48% 706
2 BRCA1 authKW 3017076 27% 36% 929
3 HEREDITARY BREAST CANCER authKW 530282 4% 49% 121
4 BRCA authKW 362303 4% 29% 138
5 BRCA1 GENE authKW 249457 2% 51% 54
6 PROPHYLACTIC MASTECTOMY authKW 242831 2% 48% 56
7 BRCA2 GENE authKW 212036 1% 64% 37
8 FAMILIAL BREAST CANCER authKW 186880 2% 35% 60
9 FAMILIAL CANCER journal 181611 4% 15% 133
10 HEREDITARY BREAST AND OVARIAN CANCER authKW 175975 1% 43% 46

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 40375 56% 0% 1903
2 Genetics & Heredity 14023 27% 0% 928
3 Obstetrics & Gynecology 2624 9% 0% 309
4 Medicine, General & Internal 353 6% 0% 218
5 Pathology 235 3% 0% 104
6 Mathematical & Computational Biology 141 2% 0% 51
7 Public, Environmental & Occupational Health 138 4% 0% 138
8 Medicine, Research & Experimental 106 3% 0% 113
9 Surgery 65 5% 0% 162
10 Medical Laboratory Technology 27 1% 0% 25

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLIN CANC GENET 100257 1% 23% 49
2 FAMILY CANC CLIN 88133 1% 21% 47
3 PROGRAM CANC GENET 85461 1% 20% 48
4 INT HEREDITARY CANC 74478 1% 18% 46
5 SERV GENET ONCOL 67043 1% 27% 28
6 HEREDITARY CANC 63623 1% 24% 30
7 UNITE GENET ONCOL 63156 0% 47% 15
8 GILDA RADNER FAMILIAL OVARIAN CANC REGISTRY 55974 0% 69% 9
9 FAMILY HIST CLIN 55028 0% 88% 7
10 SERV BIOPATOL CLIN 55028 0% 88% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FAMILIAL CANCER 181611 4% 15% 133
2 HEREDITARY CANCER IN CLINICAL PRACTICE 87015 1% 23% 42
3 BREAST CANCER RESEARCH AND TREATMENT 66112 7% 3% 231
4 HUMAN MUTATION 15479 2% 2% 83
5 JOURNAL OF MEDICAL GENETICS 13304 3% 2% 93
6 CLINICAL GENETICS 10356 2% 2% 77
7 BREAST CANCER RESEARCH 8679 1% 2% 46
8 GENETIC TESTING 8002 1% 4% 24
9 JOURNAL OF CLINICAL ONCOLOGY 6679 3% 1% 111
10 AMERICAN JOURNAL OF HUMAN GENETICS 5848 2% 1% 73

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BRCA2 3049781 21% 48% 706 Search BRCA2 Search BRCA2
2 BRCA1 3017076 27% 36% 929 Search BRCA1 Search BRCA1
3 HEREDITARY BREAST CANCER 530282 4% 49% 121 Search HEREDITARY+BREAST+CANCER Search HEREDITARY+BREAST+CANCER
4 BRCA 362303 4% 29% 138 Search BRCA Search BRCA
5 BRCA1 GENE 249457 2% 51% 54 Search BRCA1+GENE Search BRCA1+GENE
6 PROPHYLACTIC MASTECTOMY 242831 2% 48% 56 Search PROPHYLACTIC+MASTECTOMY Search PROPHYLACTIC+MASTECTOMY
7 BRCA2 GENE 212036 1% 64% 37 Search BRCA2+GENE Search BRCA2+GENE
8 FAMILIAL BREAST CANCER 186880 2% 35% 60 Search FAMILIAL+BREAST+CANCER Search FAMILIAL+BREAST+CANCER
9 HEREDITARY BREAST AND OVARIAN CANCER 175975 1% 43% 46 Search HEREDITARY+BREAST+AND+OVARIAN+CANCER Search HEREDITARY+BREAST+AND+OVARIAN+CANCER
10 BRCA1 2 163792 2% 30% 61 Search BRCA1+2 Search BRCA1+2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KARAMI, F , MEHDIPOUR, P , (2013) A COMPREHENSIVE FOCUS ON GLOBAL SPECTRUM OF BRCA1 AND BRCA2 MUTATIONS IN BREAST CANCER.BIOMED RESEARCH INTERNATIONAL. VOL. . ISSUE . P. - 154 87% 14
2 FACKENTHAL, JD , OLOPADE, OI , (2007) BREAST CANCER RISK ASSOCIATED WITH BRCA1 AND BRCA2 IN DIVERSE POPULATIONS.NATURE REVIEWS CANCER. VOL. 7. ISSUE 12. P. 937 -948 121 78% 177
3 KWONG, A , SHIN, VY , HO, JCW , KANG, E , NAKAMURA, S , TEO, SH , LEE, ASG , SNG, JH , GINSBURG, OM , KURIAN, AW , ET AL (2016) COMPREHENSIVE SPECTRUM OF BRCA1 AND BRCA2 DELETERIOUS MUTATIONS IN BREAST CANCER IN ASIAN COUNTRIES.JOURNAL OF MEDICAL GENETICS. VOL. 53. ISSUE 1. P. 15 -23 67 94% 5
4 MAVADDAT, N , PEOCK, S , FROST, D , ELLIS, S , PLATTE, R , FINEBERG, E , EVANS, DG , IZATT, L , EELES, RA , ADLARD, J , ET AL (2013) CANCER RISKS FOR BRCA1 AND BRCA2 MUTATION CARRIERS: RESULTS FROM PROSPECTIVE ANALYSIS OF EMBRACE.JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. VOL. 105. ISSUE 11. P. 812-822 55 82% 148
5 KIM, H , CHOI, DH , (2013) DISTRIBUTION OF BRCA1 AND BRCA2 MUTATIONS IN ASIAN PATIENTS WITH BREAST CANCER.JOURNAL OF BREAST CANCER. VOL. 16. ISSUE 4. P. 357-365 76 94% 7
6 VALLEE, MP , DI SERA, TL , NIX, DA , PAQUETTE, AM , PARSONS, MT , BELL, R , HOFFMAN, A , HOGERVORST, FBL , GOLDGAR, DE , SPURDLE, AB , ET AL (2016) ADDING IN SILICO ASSESSMENT OF POTENTIAL SPLICE ABERRATION TO THE INTEGRATED EVALUATION OF BRCA GENE UNCLASSIFIED VARIANTS.HUMAN MUTATION. VOL. 37. ISSUE 7. P. 627 -639 70 85% 2
7 SLUITER, MD , VAN RENSBURG, EJ , (2011) LARGE GENOMIC REARRANGEMENTS OF THE BRCA1 AND BRCA2 GENES: REVIEW OF THE LITERATURE AND REPORT OF A NOVEL BRCA1 MUTATION.BREAST CANCER RESEARCH AND TREATMENT. VOL. 125. ISSUE 2. P. 325 -349 69 93% 40
8 PETRUCELLI, N , DALY, MB , FELDMAN, GL , (2010) HEREDITARY BREAST AND OVARIAN CANCER DUE TO MUTATIONS IN BRCA1 AND BRCA2.GENETICS IN MEDICINE. VOL. 12. ISSUE 5. P. 245 -259 97 67% 54
9 HARTMANN, LC , LINDOR, NM , (2016) THE ROLE OF RISK-REDUCING SURGERY IN HEREDITARY BREAST AND OVARIAN CANCER.NEW ENGLAND JOURNAL OF MEDICINE. VOL. 374. ISSUE 5. P. 454 -468 48 76% 13
10 RAMUS, SJ , GAYTHER, SA , (2009) THE CONTRIBUTION OF BRCA1 AND BRCA2 TO OVARIAN CANCER.MOLECULAR ONCOLOGY. VOL. 3. ISSUE 2. P. 138 -150 79 83% 55

Classes with closest relation at Level 1


Rank Class id link
1 5107 BRCA1//BARD1//BRCA2
2 15199 CHEK2//PALB2//CHK2
3 18965 CONTRALATERAL PROPHYLACTIC MASTECTOMY//BILATERAL BREAST CANCER//CONTRALATERAL BREAST CANCER
4 3083 GENETIC TESTING//GENETIC COUNSELING//JOURNAL OF GENETIC COUNSELING
5 17719 CANC GENET EPIDEMIOL//SERV CIRUGIA GEN ESPECIALIDADES//UNIT MOL BASES GENET RISK GENET TESTING
6 9457 FAMILY HEALTH HISTORY//FAMILY HISTORY//GENETICS EDUCATION
7 19114 LI FRAUMENI SYNDROME//LI FRAUMENI//GERMLINE TP53 MUTATION
8 10428 BAZEDOXIFENE//RALOXIFENE//TISSUE SELECTIVE ESTROGEN COMPLEX
9 10345 PARP INHIBITORS//OLAPARIB//SYNTHETIC LETHALITY
10 9584 SEROUS TUBAL INTRAEPITHELIAL CARCINOMA//FALLOPIAN TUBE//SEROUS CARCINOMA

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