Class information for:
Level 1: PKN//PRK1//PKN ALPHA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
34692 108 42.5 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
1220 2             PTEN//MTOR//COWDEN SYNDROME 9128
34692 1                   PKN//PRK1//PKN ALPHA 108

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PKN authKW 3645277 18% 68% 19
2 PRK1 authKW 753963 4% 67% 4
3 PKN ALPHA authKW 565474 2% 100% 2
4 PROTEIN KINASE N PKN authKW 565474 2% 100% 2
5 PRK2 authKW 508924 3% 60% 3
6 PROTEIN KINASE C RELATED KINASE authKW 508924 3% 60% 3
7 AGC KINASE FAMILY authKW 282737 1% 100% 1
8 ANDROGEN RECEPTOR DEPENDENT TUMORS authKW 282737 1% 100% 1
9 BETA AND GAMMA CATENIN authKW 282737 1% 100% 1
10 BIO NEUROBIOCHEM address 282737 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 755 68% 0% 73
2 Cell Biology 366 31% 0% 33
3 Biophysics 162 15% 0% 16
4 Developmental Biology 49 5% 0% 5
5 Genetics & Heredity 23 7% 0% 8
6 Oncology 4 6% 0% 6
7 Biology 2 2% 0% 2
8 Multidisciplinary Sciences 2 1% 0% 1
9 Peripheral Vascular Diseases 1 2% 0% 2
10 Neurosciences 1 5% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIO NEUROBIOCHEM 282737 1% 100% 1
2 CANC UK ONCOGENE 282737 1% 100% 1
3 GENET MANIPULAT SERV 282737 1% 100% 1
4 PROT PHOSPHORYLAT 169625 8% 7% 9
5 COMPARAT MED OURCES 141368 1% 50% 1
6 BIOSIGNAL 116058 14% 3% 15
7 KINASE BIOL 94244 1% 33% 1
8 PFIZER ONCOL UNIT 94244 1% 33% 1
9 SCI BIOL NADA KU 94244 1% 33% 1
10 ZENT KLIN FOR 75393 2% 13% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOLOGICAL CHEMISTRY 737 19% 0% 20
2 CURRENT NEUROPHARMACOLOGY 535 1% 0% 1
3 JOURNAL OF BIOCHEMISTRY 417 4% 0% 4
4 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 410 9% 0% 10
5 MOLECULAR ONCOLOGY 377 1% 0% 1
6 CELLULAR SIGNALLING 257 2% 0% 2
7 MOLECULAR BRAIN RESEARCH 248 2% 0% 2
8 G3-GENES GENOMES GENETICS 208 1% 0% 1
9 DEVELOPMENTAL BIOLOGY 181 3% 0% 3
10 JOURNAL OF BURN CARE & RESEARCH 181 1% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PKN 3645277 18% 68% 19 Search PKN Search PKN
2 PRK1 753963 4% 67% 4 Search PRK1 Search PRK1
3 PKN ALPHA 565474 2% 100% 2 Search PKN+ALPHA Search PKN+ALPHA
4 PROTEIN KINASE N PKN 565474 2% 100% 2 Search PROTEIN+KINASE+N+PKN Search PROTEIN+KINASE+N+PKN
5 PRK2 508924 3% 60% 3 Search PRK2 Search PRK2
6 PROTEIN KINASE C RELATED KINASE 508924 3% 60% 3 Search PROTEIN+KINASE+C+RELATED+KINASE Search PROTEIN+KINASE+C+RELATED+KINASE
7 AGC KINASE FAMILY 282737 1% 100% 1 Search AGC+KINASE+FAMILY Search AGC+KINASE+FAMILY
8 ANDROGEN RECEPTOR DEPENDENT TUMORS 282737 1% 100% 1 Search ANDROGEN+RECEPTOR+DEPENDENT+TUMORS Search ANDROGEN+RECEPTOR+DEPENDENT+TUMORS
9 BETA AND GAMMA CATENIN 282737 1% 100% 1 Search BETA+AND+GAMMA+CATENIN Search BETA+AND+GAMMA+CATENIN
10 CONSTITUTIVELY ACTIVE FRAGMENT 282737 1% 100% 1 Search CONSTITUTIVELY+ACTIVE+FRAGMENT Search CONSTITUTIVELY+ACTIVE+FRAGMENT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 THAUERER, B , ZUR NEDDEN, S , BAIER-BITTERLICH, G , (2014) PROTEIN KINASE C-RELATED KINASE (PKN/PRK). POTENTIAL KEY-ROLE FOR PKN1 IN PROTECTION OF HYPOXIC NEURONS.CURRENT NEUROPHARMACOLOGY. VOL. 12. ISSUE 3. P. 213 -218 50 68% 1
2 BETSON, M , SETTLEMAN, J , (2007) A RHO-BINDING PROTEIN KINASE C-LIKE ACTIVITY IS REQUIRED FOR THE FUNCTION OF PROTEIN KINASE N IN DROSOPHILA DEVELOPMENT.GENETICS. VOL. 176. ISSUE 4. P. 2201-2212 38 66% 8
3 LACHMANN, S , JEVONS, A , DE RYCKER, M , CASAMASSIMA, A , RADTKE, S , COLLAZOS, A , PARKER, PJ , (2011) REGULATORY DOMAIN SELECTIVITY IN THE CELL-TYPE SPECIFIC PKN-DEPENDENCE OF CELL MIGRATION.PLOS ONE. VOL. 6. ISSUE 7. P. - 31 65% 20
4 HUTCHINSON, CL , LOWE, PN , MCLAUGHLIN, SH , MOTT, HR , OWEN, D , (2013) DIFFERENTIAL BINDING OF RHOA, RHOB, AND RHOC TO PROTEIN KINASE C-RELATED KINASE (PRK) ISOFORMS PRK1, PRK2, AND PRK3: PRKS HAVE THE HIGHEST AFFINITY FOR RHOB.BIOCHEMISTRY. VOL. 52. ISSUE 45. P. 7999-8011 29 58% 6
5 MUKAI, H , (2003) THE STRUCTURE AND FUNCTION OF PKN, A PROTEIN KINASE HAVING A CATALYTIC DOMAIN HOMOLOGOUS TO THAT OF PKC.JOURNAL OF BIOCHEMISTRY. VOL. 133. ISSUE 1. P. 17-27 44 38% 89
6 MUKAI, H , MURAMATSU, A , MASHUD, R , KUBOUCHI, K , TSUJIMOTO, S , HONGU, T , KANAHO, Y , TSUBAKI, M , NISHIDA, S , SHIOI, G , ET AL (2016) PKN3 IS THE MAJOR REGULATOR OF ANGIOGENESIS AND TUMOR METASTASIS IN MICE.SCIENTIFIC REPORTS. VOL. 6. ISSUE . P. - 32 42% 0
7 COLLAZOS, A , MICHAEL, N , WHELAN, RDH , KELLY, G , MELLOR, H , PANG, LCH , TOTTY, N , PARKER, PJ , (2011) SITE RECOGNITION AND SUBSTRATE SCREENS FOR PKN FAMILY PROTEINS.BIOCHEMICAL JOURNAL. VOL. 438. ISSUE . P. 535-543 26 51% 8
8 MUKAI, H , ONO, Y , (2006) PURIFICATION AND KINASE ASSAY OF PKN.METHODS IN ENZYMOLOGY, VOL 406, REGULATORS AND EFFECTORS OF SMALL GTPASES: RHO FAMILY. VOL. 406. ISSUE . P. 234 -250 22 63% 5
9 MUKAI, H , ONO, Y , (1998) PROTEIN KINASE PKN.SEIKAGAKU. VOL. 70. ISSUE 11. P. 1335-1339 17 100% 0
10 BAUER, AF , SONZOGNI, S , MEYER, L , ZEUZEM, S , PIIPER, A , BIONDI, RM , NEIMANIS, S , (2012) REGULATION OF PROTEIN KINASE C-RELATED PROTEIN KINASE 2 (PRK2) BY AN INTERMOLECULAR PRK2-PRK2 INTERACTION MEDIATED BY ITS N-TERMINAL DOMAIN.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 24. P. 20590-20602 23 43% 7

Classes with closest relation at Level 1


Rank Class id link
1 1558 RHO GTPASES//TIAM1//RHOB
2 6528 PDK1//AKT//AKT2
3 7347 FASUDIL//RHO KINASE//Y 27632
4 1767 PROTEIN KINASE C//PKC DELTA//CELLULAR CARCINOGENESIS TUMOR PROMOT
5 25967 GUANOSINE//GUANINE BASED PURINES//AIT 082
6 19607 MARCKS//MYRISTOYLATED ALANINE RICH C KINASE SUBSTRATE//MARCKS RELATED PROTEIN
7 14515 S6K2//P70 S6 KINASE//RIBOSOMAL S6 KINASE 2 S6K2
8 11502 PAK1//P21 ACTIVATED KINASE//PAK4
9 19765 A20//RNF11//ZINC FINGER PROTEIN A20
10 33774 CANC MICROARRAY GENES PROT//SPERM PROTEIN 17//SPAG9

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