Class information for:
Level 1: SOTALOL//DOFETILIDE//CLASS III ANTIARRHYTHMIC AGENT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7162 1398 30.9 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
896 2             AMIODARONE//ANTIARRHYTHMIC DRUGS//PROPAFENONE 11339
7162 1                   SOTALOL//DOFETILIDE//CLASS III ANTIARRHYTHMIC AGENT 1398

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SOTALOL authKW 684292 7% 34% 93
2 DOFETILIDE authKW 552058 5% 40% 63
3 CLASS III ANTIARRHYTHMIC AGENT authKW 440425 2% 61% 33
4 AZIMILIDE authKW 378551 2% 67% 26
5 MS 551 authKW 371289 1% 100% 17
6 D SOTALOL authKW 353203 2% 56% 29
7 CLASS III ANTIARRHYTHMIC DRUGS authKW 306101 2% 48% 29
8 SEMATILIDE authKW 294267 1% 84% 16
9 TEDISAMIL authKW 285680 2% 59% 22
10 CLASS III ANTIARRHYTHMICS authKW 278553 2% 51% 25

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cardiac & Cardiovascular System 28756 56% 0% 782
2 Pharmacology & Pharmacy 7387 43% 0% 599
3 Peripheral Vascular Diseases 726 7% 0% 103
4 Engineering, Biomedical 277 4% 0% 57
5 Chemistry, Medicinal 216 4% 0% 62
6 Physiology 22 2% 0% 34
7 Toxicology 14 2% 0% 25
8 Emergency Medicine 8 1% 0% 7
9 Critical Care Medicine 6 1% 0% 11
10 Medicine, General & Internal 6 3% 0% 40

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANESTHESIOL EXPT PHYSIOL CELLULAIRE E3212 43681 0% 100% 2
2 DIPARTIMENTO MED INTERNA SEZ CARDIOL 43681 0% 100% 2
3 ANESTHESIOL CLIN 1MED 21841 0% 100% 1
4 ARTERIOSKLEROSIS 21841 0% 100% 1
5 CARDIAC UNIT CARDIAC ARRHYTHMIA SERV 21841 0% 100% 1
6 CARDIOL 8TH AVE C ST 21841 0% 100% 1
7 CARDIOL SECT 691111E 21841 0% 100% 1
8 CARDIOLCARDIOL SECT691111E 21841 0% 100% 1
9 CARDIOVASC DIS 7243209307 21841 0% 100% 1
10 CENT LIFE SCI 21841 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 41750 10% 1% 145
2 CARDIOVASCULAR DRUG REVIEWS 7465 1% 3% 12
3 AMERICAN JOURNAL OF CARDIOLOGY 6861 7% 0% 92
4 CARDIOVASCULAR RESEARCH 6648 4% 1% 49
5 PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY 5893 4% 1% 49
6 CARDIOVASCULAR DRUGS AND THERAPY 4939 2% 1% 21
7 JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY 4611 2% 1% 30
8 AMERICAN HEART JOURNAL 4382 4% 0% 54
9 EUROPEAN HEART JOURNAL 4323 3% 0% 45
10 METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 2686 1% 1% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SOTALOL 684292 7% 34% 93 Search SOTALOL Search SOTALOL
2 DOFETILIDE 552058 5% 40% 63 Search DOFETILIDE Search DOFETILIDE
3 CLASS III ANTIARRHYTHMIC AGENT 440425 2% 61% 33 Search CLASS+III+ANTIARRHYTHMIC+AGENT Search CLASS+III+ANTIARRHYTHMIC+AGENT
4 AZIMILIDE 378551 2% 67% 26 Search AZIMILIDE Search AZIMILIDE
5 MS 551 371289 1% 100% 17 Search MS+551 Search MS+551
6 D SOTALOL 353203 2% 56% 29 Search D+SOTALOL Search D+SOTALOL
7 CLASS III ANTIARRHYTHMIC DRUGS 306101 2% 48% 29 Search CLASS+III+ANTIARRHYTHMIC+DRUGS Search CLASS+III+ANTIARRHYTHMIC+DRUGS
8 SEMATILIDE 294267 1% 84% 16 Search SEMATILIDE Search SEMATILIDE
9 TEDISAMIL 285680 2% 59% 22 Search TEDISAMIL Search TEDISAMIL
10 CLASS III ANTIARRHYTHMICS 278553 2% 51% 25 Search CLASS+III+ANTIARRHYTHMICS Search CLASS+III+ANTIARRHYTHMICS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FITTON, A , SORKIN, EM , (1993) SOTALOL - AN UPDATED REVIEW OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC USE IN CARDIAC-ARRHYTHMIAS.DRUGS. VOL. 46. ISSUE 4. P. 678 -719 139 70% 42
2 CLAUDEL, JP , TOUBOUL, P , (1995) SOTALOL - FROM JUST ANOTHER BETA-BLOCKER TO THE PROTOTYPE OF CLASS-III ANTIDYSRHYTHMIC COMPOUND.PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY. VOL. 18. ISSUE 3. P. 451-467 68 88% 16
3 NAIR, LA , GRANT, AO , (1997) EMERGING CLASS III ANTIARRHYTHMIC AGENTS: MECHANISM OF ACTION AND PROARRHYTHMIC POTENTIAL.CARDIOVASCULAR DRUGS AND THERAPY. VOL. 11. ISSUE 2. P. 149-167 62 56% 45
4 HOHNLOSER, SH , WOOSLEY, RL , (1994) DRUG-THERAPY - SOTALOL.NEW ENGLAND JOURNAL OF MEDICINE. VOL. 331. ISSUE 1. P. 31-38 48 70% 123
5 MOUNSEY, JP , DIMARCO, JP , (2000) DOFETILIDE.CIRCULATION. VOL. 102. ISSUE 21. P. 2665 -2670 37 73% 47
6 FUNCKBRENTANO, C , (1993) PHARMACOKINETIC AND PHARMACODYNAMIC PROFILES OF D-SOTALOL AND D,L-SOTALOL.EUROPEAN HEART JOURNAL. VOL. 14. ISSUE . P. 30-35 37 93% 20
7 ANDERSON, JL , PRYSTOWSKY, EN , (1999) SOTALOL: AN IMPORTANT NEW ANTIARRHYTHMIC.AMERICAN HEART JOURNAL. VOL. 137. ISSUE 3. P. 388 -409 39 64% 51
8 COLATSKY, TJ , ARGENTIERI, TM , (1994) POTASSIUM CHANNEL BLOCKERS AS ANTIARRHYTHMIC DRUGS.DRUG DEVELOPMENT RESEARCH. VOL. 33. ISSUE 3. P. 235 -249 39 75% 39
9 FALK, RH , DECARA, JM , (2000) DOFETILIDE: A NEW PURE CLASS III ANTIARRHYTHMIC AGENT.AMERICAN HEART JOURNAL. VOL. 140. ISSUE 5. P. 697 -706 32 76% 15
10 KALUS, JS , MAURO, VF , (2000) DOFETILIDE: A CLASS III-SPECIFIC ANTIARRHYTHMIC AGENT.ANNALS OF PHARMACOTHERAPY. VOL. 34. ISSUE 1. P. 44 -56 31 78% 8

Classes with closest relation at Level 1


Rank Class id link
1 3490 HERG//I KR//HERG CHANNEL
2 15182 ANIPAMIL//KINGS CARDIOVASC BIOL MED//ISCHEMIA AND RE PERFUSION
3 3840 CARDIAC & CARDIOVASCULAR SYSTEM//PROGRAMMED VENTRICULAR STIMULATION//ELECTROPHYSIOLOGICAL TESTING
4 34620 BDF 9148//DPI 201 106//NA CHANNEL ACTIVATOR
5 27637 N ACETYLPROCAINAMIDE//ABUNDANCE OF ECTOPARASITES//ANTIARRHYTHMIC PROCANBIDR
6 3886 AMIODARONE//DESETHYLAMIODARONE//INTRAVENOUS AMIODARONE
7 3795 PROPAFENONE//FLECAINIDE//MEXILETINE
8 1469 ATRIAL FIBRILLATION//DRONEDARONE//CARDIOVERSION
9 2028 QT DISPERSION//QT INTERVAL//REPOLARIZATION
10 7026 TRANSIENT OUTWARD CURRENT//KV43//KCHIP

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