Class information for:
Level 1: FACTOR VA//FACTOR V DEFICIENCY//PROTHROMBINASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3016 2085 41.6 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
111 3       THROMBOSIS RESEARCH//THROMBOSIS AND HAEMOSTASIS//HEMATOLOGY 71244
637 2             TISSUE FACTOR//THROMBOMODULIN//PROTEIN C 13723
3016 1                   FACTOR VA//FACTOR V DEFICIENCY//PROTHROMBINASE 2085

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FACTOR VA authKW 398944 2% 72% 38
2 FACTOR V DEFICIENCY authKW 272999 2% 55% 34
3 PROTHROMBINASE authKW 154544 2% 33% 32
4 FACTOR V authKW 150836 3% 17% 61
5 DYSPROTHROMBINEMIA authKW 147653 1% 92% 11
6 PROTHROMBIN authKW 140441 3% 14% 69
7 PROTHROMBIN DEFICIENCY authKW 131785 1% 75% 12
8 FACTOR IXA authKW 112452 1% 40% 19
9 EDWARD A DOISY BIOCHEM MOL BIOL address 95772 3% 12% 56
10 JOSEPH STOKES address 79739 1% 34% 16

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Hematology 14232 26% 0% 532
2 Biochemistry & Molecular Biology 12736 64% 0% 1325
3 Peripheral Vascular Diseases 4525 14% 0% 296
4 Biophysics 1016 9% 0% 187
5 Biochemical Research Methods 101 3% 0% 69
6 Cell Biology 17 4% 0% 78
7 Medicine, Research & Experimental 9 2% 0% 43
8 Medical Laboratory Technology 0 0% 0% 6
9 Biology -0 1% 0% 15
10 History & Philosophy of Science -0 0% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EDWARD A DOISY BIOCHEM MOL BIOL 95772 3% 12% 56
2 JOSEPH STOKES 79739 1% 34% 16
3 SCI SR 370 43930 0% 100% 3
4 SCI SR370 43930 0% 100% 3
5 PLASMA PROT TECHNOL 33275 0% 45% 5
6 ABRAMSON 302E 29287 0% 100% 2
7 ROSENSTEIL BASIC MED 29287 0% 100% 2
8 THROMBOSIS UNITCAMBRIDGE MED 26356 0% 60% 3
9 U428 20857 1% 12% 12
10 HEMOPHILIA TREATMENT THROMBOSIS 19523 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOLOGICAL CHEMISTRY 21376 23% 0% 471
2 BIOCHEMISTRY 20954 13% 1% 277
3 THROMBOSIS AND HAEMOSTASIS 16094 5% 1% 105
4 JOURNAL OF THROMBOSIS AND HAEMOSTASIS 12520 3% 1% 58
5 THROMBOSIS RESEARCH 12005 4% 1% 92
6 BLOOD 4744 5% 0% 107
7 HAEMOSTASIS 3004 1% 1% 16
8 BLOOD COAGULATION & FIBRINOLYSIS 2746 1% 1% 25
9 PROGRESS IN HEMOSTASIS AND THROMBOSIS 1498 0% 5% 2
10 SEMINARS IN THROMBOSIS AND HEMOSTASIS 1391 1% 1% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FACTOR VA 398944 2% 72% 38 Search FACTOR+VA Search FACTOR+VA
2 FACTOR V DEFICIENCY 272999 2% 55% 34 Search FACTOR+V+DEFICIENCY Search FACTOR+V+DEFICIENCY
3 PROTHROMBINASE 154544 2% 33% 32 Search PROTHROMBINASE Search PROTHROMBINASE
4 FACTOR V 150836 3% 17% 61 Search FACTOR+V Search FACTOR+V
5 DYSPROTHROMBINEMIA 147653 1% 92% 11 Search DYSPROTHROMBINEMIA Search DYSPROTHROMBINEMIA
6 PROTHROMBIN 140441 3% 14% 69 Search PROTHROMBIN Search PROTHROMBIN
7 PROTHROMBIN DEFICIENCY 131785 1% 75% 12 Search PROTHROMBIN+DEFICIENCY Search PROTHROMBIN+DEFICIENCY
8 FACTOR IXA 112452 1% 40% 19 Search FACTOR+IXA Search FACTOR+IXA
9 GLA DOMAIN 69985 1% 34% 14 Search GLA+DOMAIN Search GLA+DOMAIN
10 MEIZOTHROMBIN 66935 0% 57% 8 Search MEIZOTHROMBIN Search MEIZOTHROMBIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BOCK, PE , PANIZZI, P , VERHAMME, IMA , (2007) EXOSITES IN THE SUBSTRATE SPECIFICITY OF BLOOD COAGULATION REACTIONS.JOURNAL OF THROMBOSIS AND HAEMOSTASIS. VOL. 5. ISSUE . P. 81-94 118 80% 76
2 DI CERA, E , (2008) THROMBIN.MOLECULAR ASPECTS OF MEDICINE. VOL. 29. ISSUE 4. P. 203 -254 125 57% 95
3 DI CERA, E , (2011) THROMBIN AS AN ANTICOAGULANT.PROTEASES IN HEALTH AND DISEASE. VOL. 99. ISSUE . P. 145 -184 109 65% 4
4 HIRBAWI, J , YEE, VC , KALAFATIS, M , WIENCEK, JR , (2016) THE DUAL REGULATORY ROLE OF AMINO ACIDS LEU(480) AND GLN(481) OF PROTHROMBIN.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 291. ISSUE 4. P. 1565 -1581 60 83% 0
5 KROH, HK , TANS, G , NICOLAES, GAF , ROSING, J , BOCK, PE , (2007) EXPRESSION OF ALLOSTERIC LINKAGE BETWEEN THE SODIUM ION BINDING SITE AND EXOSITE I OF THROMBIN DURING PROTHROMBIN ACTIVATION.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 282. ISSUE 22. P. 16095-16104 57 98% 20
6 POZZI, N , CHEN, R , CHEN, ZW , BAH, A , DI CERA, E , (2011) RIGIDIFICATION OF THE AUTOLYSIS LOOP ENHANCES NA+ BINDING TO THROMBIN.BIOPHYSICAL CHEMISTRY. VOL. 159. ISSUE 1. P. 6 -13 64 79% 10
7 LENTZ, BR , (2003) EXPOSURE OF PLATELET MEMBRANE PHOSPHATIDYLSERINE REGULATES BLOOD COAGULATION.PROGRESS IN LIPID RESEARCH. VOL. 42. ISSUE 5. P. 423-438 70 79% 119
8 KRISHNASWAMY, S , (2013) THE TRANSITION OF PROTHROMBIN TO THROMBIN.JOURNAL OF THROMBOSIS AND HAEMOSTASIS. VOL. 11. ISSUE . P. 265-276 55 81% 17
9 QURESHI, SH , YANG, LK , MANITHODY, C , REZAIE, AR , (2009) MEMBRANE-DEPENDENT INTERACTION OF FACTOR XA AND PROTHROMBIN WITH FACTOR VA IN THE PROTHROMBINASE COMPLEX.BIOCHEMISTRY. VOL. 48. ISSUE 22. P. 5034-5041 53 98% 6
10 POZZI, N , CHEN, ZW , DI CERA, E , (2016) HOW THE LINKER CONNECTING THE TWO KRINGLES INFLUENCES ACTIVATION AND CONFORMATIONAL PLASTICITY OF PROTHROMBIN.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 291. ISSUE 12. P. 6071 -6082 46 81% 2

Classes with closest relation at Level 1


Rank Class id link
1 7211 FACTOR VIII//HEMOPHILIA A//FACTOR VIIIA
2 17027 FACTOR VII DEFICIENCY//FACTOR X DEFICIENCY//FVII DEFICIENCY
3 4860 THROMBOMODULIN//ACTIVATED PROTEIN C//ENDOTHELIAL PROTEIN C RECEPTOR
4 31191 PROTEIN Z//PROTEIN Z DEPENDENT PROTEASE INHIBITOR//PROTEIN Z DEFICIENCY
5 5039 PROTEIN S//PROTEIN C DEFICIENCY//C4B BINDING PROTEIN
6 13846 ANTICOAGULANT RESISTANCE//VKOR//GAMMA GLUTAMYL CARBOXYLASE
7 2400 THROMBIN INHIBITOR//HIRUDIN//XIMELAGATRAN
8 17915 THROMBIN GENERATION//THROMBIN GENERATION ASSAY//ENDOGENOUS THROMBIN POTENTIAL
9 23637 PROTEIN C INHIBITOR//F5F8D//LMAN1
10 942 TISSUE FACTOR//TISSUE FACTOR PATHWAY INHIBITOR//TFPI

Go to start page