Class information for:
Level 1: NXY 059//PBN//ALPHA PHENYL N TERT BUTYL NITRONE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
18680 540 40.8 77%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
258 3       STROKE//INTRACEREBRAL HEMORRHAGE//CEREBRAL ISCHEMIA 44849
359 2             CEREBRAL ISCHEMIA//SPREADING DEPRESSION//JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 17400
18680 1                   NXY 059//PBN//ALPHA PHENYL N TERT BUTYL NITRONE 540

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NXY 059 authKW 2056205 7% 91% 40
2 PBN authKW 246525 4% 20% 22
3 ALPHA PHENYL N TERT BUTYL NITRONE authKW 193854 2% 29% 12
4 ARRIVE authKW 180945 1% 80% 4
5 N TERT BUTYL ALPHA PHENYLNITRONE PBN authKW 169637 1% 100% 3
6 S PBN authKW 156582 1% 46% 6
7 SYRCLE address 141360 1% 50% 5
8 AZULENYL NITRONES authKW 113092 0% 100% 2
9 ETHICS AND WELFARE ALTERNATIVES authKW 113092 0% 100% 2
10 ETHICS AND WELFARE SUPPLEMENTS TO ANIMAL RESEARCH authKW 113092 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Clinical Neurology 926 19% 0% 103
2 Peripheral Vascular Diseases 824 12% 0% 65
3 Neurosciences 620 21% 0% 116
4 Pharmacology & Pharmacy 235 14% 0% 78
5 Medical Ethics 228 1% 0% 7
6 Biochemistry & Molecular Biology 166 19% 0% 100
7 Endocrinology & Metabolism 141 7% 0% 40
8 Ethics 119 2% 0% 9
9 Veterinary Sciences 88 6% 0% 30
10 Chemistry, Medicinal 67 4% 0% 22

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SYRCLE 141360 1% 50% 5
2 3R 113088 1% 50% 4
3 EDMONTON CLIN HLTH 4 546 75393 0% 67% 2
4 GARDINER WESTERN INFIRM 75393 0% 67% 2
5 MERRICK FDN CHAIR AGING 75393 0% 67% 2
6 FREE RAD BIOL AGING PROGRAM 70243 2% 10% 13
7 ABORAT HLTH HUMAN SERV 56546 0% 100% 1
8 ANIM EXPERIMENTAT SYRCLE 56546 0% 100% 1
9 ANIM EXPERIMENTAT SYRCLE NIJMEGEN 56546 0% 100% 1
10 ANIM WELF INITIAT 56546 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ILAR JOURNAL 12220 2% 2% 10
2 STROKE 9486 9% 0% 49
3 TRANSLATIONAL STROKE RESEARCH 4594 1% 1% 6
4 PLOS BIOLOGY 3120 2% 0% 12
5 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 3044 3% 0% 17
6 INTERNATIONAL JOURNAL OF STROKE 1942 1% 1% 6
7 FREE RADICAL BIOLOGY AND MEDICINE 1880 3% 0% 17
8 FREE RADICAL RESEARCH COMMUNICATIONS 1340 1% 1% 4
9 FREE RADICAL RESEARCH 1205 1% 0% 8
10 BMC MEDICAL ETHICS 1189 1% 1% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NXY 059 2056205 7% 91% 40 Search NXY+059 Search NXY+059
2 PBN 246525 4% 20% 22 Search PBN Search PBN
3 ALPHA PHENYL N TERT BUTYL NITRONE 193854 2% 29% 12 Search ALPHA+PHENYL+N+TERT+BUTYL+NITRONE Search ALPHA+PHENYL+N+TERT+BUTYL+NITRONE
4 ARRIVE 180945 1% 80% 4 Search ARRIVE Search ARRIVE
5 N TERT BUTYL ALPHA PHENYLNITRONE PBN 169637 1% 100% 3 Search N+TERT+BUTYL+ALPHA+PHENYLNITRONE+PBN Search N+TERT+BUTYL+ALPHA+PHENYLNITRONE+PBN
6 S PBN 156582 1% 46% 6 Search S+PBN Search S+PBN
7 AZULENYL NITRONES 113092 0% 100% 2 Search AZULENYL+NITRONES Search AZULENYL+NITRONES
8 ETHICS AND WELFARE ALTERNATIVES 113092 0% 100% 2 Search ETHICS+AND+WELFARE+ALTERNATIVES Search ETHICS+AND+WELFARE+ALTERNATIVES
9 ETHICS AND WELFARE SUPPLEMENTS TO ANIMAL RESEARCH 113092 0% 100% 2 Search ETHICS+AND+WELFARE+SUPPLEMENTS+TO+ANIMAL+RESEARCH Search ETHICS+AND+WELFARE+SUPPLEMENTS+TO+ANIMAL+RESEARCH
10 ETHICS OF ANIMAL USE 113092 0% 100% 2 Search ETHICS+OF+ANIMAL+USE Search ETHICS+OF+ANIMAL+USE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MACLEOD, MR , VAN DER WORP, HB , SENA, ES , HOWELLS, DW , DIRNAGL, U , DONNAN, GA , (2008) EVIDENCE FOR THE EFFICACY OF NXY-059 IN EXPERIMENTAL FOCAL CEREBRAL ISCHAEMIA IS CONFOUNDED BY STUDY QUALITY.STROKE. VOL. 39. ISSUE 10. P. 2824-2829 22 85% 95
2 GREEN, AR , ASHWOOD, T , ODERGREN, T , JACKSON, DM , (2003) NITRONES AS NEUROPROTECTIVE AGENTS IN CEREBRAL ISCHEMIA, WITH PARTICULAR REFERENCE TO NXY-059.PHARMACOLOGY & THERAPEUTICS. VOL. 100. ISSUE 3. P. 195 -214 52 44% 73
3 BATH, PMW , GRAY, LJ , BATH, AJG , BUCHAN, A , MIYATA, T , GREEN, AR , (2009) EFFECTS OF NXY-059 IN EXPERIMENTAL STROKE: AN INDIVIDUAL ANIMAL META-ANALYSIS.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 157. ISSUE 7. P. 1157 -1171 25 71% 51
4 LAPCHAK, PA , ARAUJO, DM , (2003) DEVELOPMENT OF THE NITRONE-BASED SPIN TRAP AGENT NXY-059 TO TREAT ACUTE ISCHEMIC STROKE.CNS DRUG REVIEWS. VOL. 9. ISSUE 3. P. 253-262 36 64% 18
5 MACLEOD, MR , MCLEAN, AL , KYRIAKOPOULOU, A , SERGHIOU, S , DE WILDE, A , SHERRATT, N , HIRST, T , HEMBLADE, R , BAHOR, Z , NUNES-FONSECA, C , ET AL (2015) RISK OF BIAS IN REPORTS OF IN VIVO RESEARCH: A FOCUS FOR IMPROVEMENT.PLOS BIOLOGY. VOL. 13. ISSUE 10. P. - 19 68% 21
6 FLOYD, RA , KOPKE, RD , CHOI, CH , FOSTER, SB , DOBLAS, S , TOWNER, RA , (2008) NITRONES AS THERAPEUTICS.FREE RADICAL BIOLOGY AND MEDICINE. VOL. 45. ISSUE 10. P. 1361-1374 49 32% 79
7 MAPLES, KR , GREEN, AR , FLOYD, RA , (2004) NITRONE-RELATED THERAPEUTICS - POTENTIAL OF NXY-059 FOR THE TREATMENT OF ACUTE ISCHAEMIC STROKE.CNS DRUGS. VOL. 18. ISSUE 15. P. 1071-1084 40 49% 36
8 VOGT, L , REICHLIN, TS , NATHUES, C , WURBEL, H , (2016) AUTHORIZATION OF ANIMAL EXPERIMENTS IS BASED ON CONFIDENCE RATHER THAN EVIDENCE OF SCIENTIFIC RIGOR.PLOS BIOLOGY. VOL. 14. ISSUE 12. P. - 23 61% 0
9 DOGGRELL, SA , (2006) NITRONE SPIN ON CEREBRAL ISCHEMIA.CURRENT OPINION IN INVESTIGATIONAL DRUGS. VOL. 7. ISSUE 1. P. 20-24 24 71% 5
10 VAN LUIJK, J , BAKKER, B , ROVERS, MM , RITSKES-HOITINGA, M , DE VRIES, RBM , LEENAARS, M , (2014) SYSTEMATIC REVIEWS OF ANIMAL STUDIES; MISSING LINK IN TRANSLATIONAL RESEARCH?.PLOS ONE. VOL. 9. ISSUE 3. P. - 12 100% 14

Classes with closest relation at Level 1


Rank Class id link
1 8317 SPIN TRAPPING//SPIN TRAP//DEPMPO
2 9006 MIDDLE CEREBRAL ARTERY OCCLUSION//EXPERIMENTAL THROMBOEMBOLISM//FOCAL CEREBRAL ISCHEMIA
3 29818 F 18 BCPP EF//INTRAUTERINE ISCHEMIA//O 15OXYGEN
4 24727 ATLA-ALTERNATIVES TO LABORATORY ANIMALS//THREE RS//ANIMAL EXPERIMENTATION
5 11410 LAZAROID//21 AMINOSTEROID//TIRILAZAD MESYLATE
6 21669 EDARAVONE//MCI 186//FREE RADICAL SCAVENGER
7 10889 LUBELUZOLE//NIMODIPINE//LEVEMOPAMIL
8 37521 3 4 AMINOPHENYL 2H CHROMEN 2 ONE//AG119//ANESTHESIOL ANAT CELL BIOL
9 35658 RESEARCH WORKFORCE DEVELOPMENT//ASSET COMMERCIALIZATION//BIOMEDICAL WORKFORCE
10 15596 VET HEKIMLIGI TARIHI DEONTOL ANABILIM DALI//ANIMAL ETHICS COMMITTEES//ANIMAL RESEARCH

Go to start page