Class information for:
Level 1: SINGLE STRANDED OLIGONUCLEOTIDES//GENE REPAIR//CHIMERAPLASTY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
25066 292 42.8 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
33 3       JOURNAL OF BACTERIOLOGY//MICROBIOLOGY//MOLECULAR MICROBIOLOGY 107033
1115 2             GENOME EDITING//CRISPR CAS9//CRISPR 9706
25066 1                   SINGLE STRANDED OLIGONUCLEOTIDES//GENE REPAIR//CHIMERAPLASTY 292

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SINGLE STRANDED OLIGONUCLEOTIDES authKW 2142146 9% 79% 26
2 GENE REPAIR authKW 1707998 10% 58% 28
3 CHIMERAPLASTY authKW 1045727 3% 100% 10
4 GENE CORRECTION authKW 803356 8% 35% 22
5 CHIMERIC RNA DNA OLIGONUCLEOTIDE authKW 705862 3% 75% 9
6 CHIMERAPLAST authKW 640506 2% 88% 7
7 RNA DNA OLIGONUCLEOTIDES authKW 640506 2% 88% 7
8 SFHR authKW 537801 2% 86% 6
9 GENE EDITING address 522864 2% 100% 5
10 TARGETED GENE ALTERATION authKW 522864 2% 100% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biotechnology & Applied Microbiology 2328 38% 0% 111
2 Medicine, Research & Experimental 2089 32% 0% 93
3 Genetics & Heredity 1706 32% 0% 94
4 Biochemistry & Molecular Biology 806 45% 0% 130
5 Cell Biology 72 10% 0% 29
6 Biophysics 25 4% 0% 13
7 Toxicology 17 3% 0% 9
8 Plant Sciences 9 4% 0% 12
9 Gastroenterology & Hepatology 8 2% 0% 7
10 Dermatology 7 2% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE EDITING 522864 2% 100% 5
2 HSRF 222 209145 1% 100% 2
3 MARSHALL INTERDISCIPLINARY 137588 2% 26% 5
4 ANTISENSE FUNCT GENOM GRP 104573 0% 100% 1
5 BIO INNOVAT ZENTRUM 104573 0% 100% 1
6 BIOCHEM MOL PHARMACOLJEFFERSON MOL M 104573 0% 100% 1
7 DIPARTIMENTO BIOPATOL IMAGING DIAGNOST 104573 0% 100% 1
8 EA PIERCE FM KIRBY MOL OPHTHALMOL 104573 0% 100% 1
9 EPI0111 104573 0% 100% 1
10 GEN ENVIRONM PHYSIOL CELL BIOL 104573 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OLIGONUCLEOTIDES 65673 4% 5% 13
2 GENE THERAPY 24048 10% 1% 30
3 JOURNAL OF GENE MEDICINE 12562 4% 1% 13
4 MOLECULAR THERAPY-NUCLEIC ACIDS 3110 1% 1% 3
5 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT 2524 1% 1% 3
6 BMC MOLECULAR BIOLOGY 2202 1% 1% 4
7 NATURE BIOTECHNOLOGY 1946 2% 0% 7
8 CURRENT OPINION IN MOLECULAR THERAPEUTICS 1909 1% 0% 4
9 DNA REPAIR 1842 2% 0% 6
10 HUMAN GENE THERAPY 1120 2% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SINGLE STRANDED OLIGONUCLEOTIDES 2142146 9% 79% 26 Search SINGLE+STRANDED+OLIGONUCLEOTIDES Search SINGLE+STRANDED+OLIGONUCLEOTIDES
2 GENE REPAIR 1707998 10% 58% 28 Search GENE+REPAIR Search GENE+REPAIR
3 CHIMERAPLASTY 1045727 3% 100% 10 Search CHIMERAPLASTY Search CHIMERAPLASTY
4 GENE CORRECTION 803356 8% 35% 22 Search GENE+CORRECTION Search GENE+CORRECTION
5 CHIMERIC RNA DNA OLIGONUCLEOTIDE 705862 3% 75% 9 Search CHIMERIC+RNA+DNA+OLIGONUCLEOTIDE Search CHIMERIC+RNA+DNA+OLIGONUCLEOTIDE
6 CHIMERAPLAST 640506 2% 88% 7 Search CHIMERAPLAST Search CHIMERAPLAST
7 RNA DNA OLIGONUCLEOTIDES 640506 2% 88% 7 Search RNA+DNA+OLIGONUCLEOTIDES Search RNA+DNA+OLIGONUCLEOTIDES
8 SFHR 537801 2% 86% 6 Search SFHR Search SFHR
9 TARGETED GENE ALTERATION 522864 2% 100% 5 Search TARGETED+GENE+ALTERATION Search TARGETED+GENE+ALTERATION
10 TARGETED GENE REPAIR 514814 3% 62% 8 Search TARGETED+GENE+REPAIR Search TARGETED+GENE+REPAIR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DE SEMIR, D , ARAN, JM , (2006) TARGETED GENE REPAIR: THE UPS AND DOWNS OF A PROMISING GENE THERAPY APPROACH.CURRENT GENE THERAPY. VOL. 6. ISSUE 4. P. 481-504 87 53% 19
2 RIVERA-TORRES, N , KMIEC, EB , (2016) GENETIC SPELL-CHECKING: GENE EDITING USING SINGLE-STRANDED DNA OLIGONUCLEOTIDES.PLANT BIOTECHNOLOGY JOURNAL. VOL. 14. ISSUE 2. P. 463 -470 48 62% 2
3 AARTS, M , RIELE, HT , (2011) PROGRESS AND PROSPECTS: OLIGONUCLEOTIDE-DIRECTED GENE MODIFICATION IN MOUSE EMBRYONIC STEM CELLS: A ROUTE TO THERAPEUTIC APPLICATION.GENE THERAPY. VOL. 18. ISSUE 3. P. 213 -219 51 68% 13
4 SUZUKI, T , (2008) TARGETED GENE MODIFICATION BY OLIGONUCLEOTIDES AND SMALL DNA FRAGMENTS IN EUKARYOTES.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 13. ISSUE . P. 737 -744 49 67% 5
5 YIN, WX , WU, XS , LIU, G , LI, ZH , WATT, RM , HUANG, JD , LIU, DP , LIANG, CC , (2005) TARGETED CORRECTION OF A CHROMOSOMAL POINT MUTATION BY MODIFIED SINGLE-STRANDED OLIGONUCLEOTIDES IN A GFP RECOVERY SYSTEM.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 334. ISSUE 4. P. 1032-1041 34 97% 16
6 IGOUCHEVA, O , ALEXEEV, V , YOON, K , (2004) OLIGONUCLEOTIDE-DIRECTED MUTAGENESIS AND TARGETED GENE CORRECTION: A MECHANISTIC POINT OF VIEW.CURRENT MOLECULAR MEDICINE. VOL. 4. ISSUE 5. P. 445 -463 62 52% 46
7 SAUER, NJ , MOZORUK, J , MILLER, RB , WARBURG, ZJ , WALKER, KA , BEETHAM, PR , SCHOPKE, CR , GOCAL, GFW , (2016) OLIGONUCLEOTIDE-DIRECTED MUTAGENESIS FOR PRECISION GENE EDITING.PLANT BIOTECHNOLOGY JOURNAL. VOL. 14. ISSUE 2. P. 496 -502 30 57% 6
8 PAPAIOANNOU, I , SIMONS, JP , OWEN, JS , (2012) OLIGONUCLEOTIDE-DIRECTED GENE-EDITING TECHNOLOGY: MECHANISMS AND FUTURE PROSPECTS.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 12. ISSUE 3. P. 329-342 44 56% 11
9 LIU, L , PAREKH-OLMEDO, H , KMIEC, EB , (2003) THE DEVELOPMENT AND REGULATION OF GENE REPAIR.NATURE REVIEWS GENETICS. VOL. 4. ISSUE 9. P. 679-689 51 59% 45
10 SARGENT, RG , KIM, S , GRUENERT, DC , (2011) OLIGO/POLYNUCLEOTIDE-BASED GENE MODIFICATION: STRATEGIES AND THERAPEUTIC POTENTIAL.OLIGONUCLEOTIDES. VOL. 21. ISSUE 2. P. 55 -75 75 32% 11

Classes with closest relation at Level 1


Rank Class id link
1 12165 GENE TARGETING//SOMATIC CELL AND MOLECULAR GENETICS//HOMOLOGOUS RECOMBINATION
2 17872 EXON SKIPPING//MC LOCKWOOD MUSCULAR DYSTROPHY//NEUROMUSCULAR ALS
3 29487 PINK EYED UNSTABLE//RADIAT ON AB MOL CELLULAR RADIAT BIOL//3 5 EXONUCLEASE
4 3100 TRIPLEX DNA//TRIPLEX//DNA TRIPLEX
5 4671 RAD51//RAD52//HOMOLOGOUS RECOMBINATION
6 915 GENOME EDITING//CRISPR//CRISPR CAS9
7 8496 RECBCD//RECBCD ENZYME//RECOMBINEERING
8 4991 RECA PROTEIN//RECA//LEXA REPRESSOR
9 4599 MISMATCH REPAIR//MUTS//DNA MISMATCH REPAIR
10 15145 MARKER FREE//MARKER FREE TRANSGENIC PLANTS//SITE SPECIFIC RECOMBINATION

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