Class information for:
Level 1: PHLIP//TUMOR ACIDITY//TUMOR PH

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16621 644 35.8 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
408 3       CHIM BIOINORGAN//POLO SCI//CARBONIC ANHYDRASE 29468
1816 2             INTERNATIONAL JOURNAL OF HYPERTHERMIA//HYPERTHERMIA//ISOLATED LIMB PERFUSION 6226
16621 1                   PHLIP//TUMOR ACIDITY//TUMOR PH 644

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHLIP authKW 349135 1% 82% 9
2 TUMOR ACIDITY authKW 318718 2% 61% 11
3 TUMOR PH authKW 189640 2% 33% 12
4 PH LOW INSERTION PEPTIDE authKW 106680 0% 75% 3
5 ACUTE ACIDIFICATION authKW 94828 0% 100% 2
6 ADAPTATION TO LOW PHE authKW 94828 0% 100% 2
7 IN VIVO IMAGING RD address 94828 0% 100% 2
8 INHIBITION OF PH REGULATION authKW 94828 0% 100% 2
9 MEMBRANE ASSOCIATED FOLDING authKW 94828 0% 100% 2
10 NUCLEAR ASSOCIATED PROTEINS authKW 94828 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 6722 53% 0% 339
2 Radiology, Nuclear Medicine & Medical Imaging 1593 20% 0% 129
3 Biophysics 343 9% 0% 60
4 Biology 309 7% 0% 44
5 Cell Biology 105 9% 0% 55
6 Medicine, Research & Experimental 66 5% 0% 32
7 Biochemistry & Molecular Biology 64 13% 0% 83
8 Physiology 49 4% 0% 26
9 Biochemical Research Methods 39 4% 0% 23
10 Multidisciplinary Sciences 21 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IN VIVO IMAGING RD 94828 0% 100% 2
2 CANC BIOL PH D PROGRAM 63217 0% 67% 2
3 ADV MED SCI TECHNOL ASSOSIAT 47414 0% 100% 1
4 ANTOINE LACASSAGNEUMR 7284 47414 0% 100% 1
5 BIOENGN EXPERIENCES TEACHERS PROGRAM 47414 0% 100% 1
6 BIOMED MASS SPE OMETRY OURCE 47414 0% 100% 1
7 CANAC PREVENT 47414 0% 100% 1
8 CHEM CAMPUS BOX 1134 1 BROOKINGS DR 47414 0% 100% 1
9 CHEM CAMPUS BOX 1134 1 BROOKINGS DR ST 47414 0% 100% 1
10 CHUCEA 47414 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNATIONAL JOURNAL OF HYPERTHERMIA 20540 5% 1% 29
2 EKSPERIMENTALNAYA ONKOLOGIYA 20248 4% 2% 23
3 ARCHIV FUR GESCHWULSTFORSCHUNG 6198 1% 2% 7
4 CANCER RESEARCH 5092 10% 0% 65
5 RADIATION RESEARCH 3465 3% 0% 22
6 INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 2273 5% 0% 29
7 BRITISH JOURNAL OF CANCER 2042 4% 0% 28
8 LASER FOCUS-ELECTRO-OPTICS 1021 0% 1% 2
9 NEOPLASIA 1003 1% 0% 6
10 CLINICAL & EXPERIMENTAL METASTASIS 845 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PHLIP 349135 1% 82% 9 Search PHLIP Search PHLIP
2 TUMOR ACIDITY 318718 2% 61% 11 Search TUMOR+ACIDITY Search TUMOR+ACIDITY
3 TUMOR PH 189640 2% 33% 12 Search TUMOR+PH Search TUMOR+PH
4 PH LOW INSERTION PEPTIDE 106680 0% 75% 3 Search PH+LOW+INSERTION+PEPTIDE Search PH+LOW+INSERTION+PEPTIDE
5 ACUTE ACIDIFICATION 94828 0% 100% 2 Search ACUTE+ACIDIFICATION Search ACUTE+ACIDIFICATION
6 ADAPTATION TO LOW PHE 94828 0% 100% 2 Search ADAPTATION+TO+LOW+PHE Search ADAPTATION+TO+LOW+PHE
7 INHIBITION OF PH REGULATION 94828 0% 100% 2 Search INHIBITION+OF+PH+REGULATION Search INHIBITION+OF+PH+REGULATION
8 MEMBRANE ASSOCIATED FOLDING 94828 0% 100% 2 Search MEMBRANE+ASSOCIATED+FOLDING Search MEMBRANE+ASSOCIATED+FOLDING
9 NUCLEAR ASSOCIATED PROTEINS 94828 0% 100% 2 Search NUCLEAR+ASSOCIATED+PROTEINS Search NUCLEAR+ASSOCIATED+PROTEINS
10 PH LOW INSERTION PEPTIDE PHLIP 94828 0% 100% 2 Search PH+LOW+INSERTION+PEPTIDE+PHLIP Search PH+LOW+INSERTION+PEPTIDE+PHLIP

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 VAN DEN BERG, AP , VAN DEN BERG-BLOK, AE , KAL, HB , REINHOLD, HS , (2001) A MODERATE ELEVATION OF BLOOD GLUCOSE LEVEL INCREASES THE EFFECTIVENESS OF THERMORADIOTHERAPY IN A RAT TUMOR MODEL I. RELATIVE CONTRIBUTIONS OF GLUCOSE AND HEATING TO TUMOR ACIDIFICATION.INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. VOL. 50. ISSUE 3. P. 783 -792 39 91% 6
2 TAPMEIER, TT , MOSHNIKOVA, A , BEECH, J , ALLEN, D , KINCHESH, P , SMART, S , HARRIS, A , MCINTYRE, A , ENGELMAN, DM , ANDREEV, OA , ET AL (2015) THE PH LOW INSERTION PEPTIDE PHLIP VARIANT 3 AS A NOVEL MARKER OF ACIDIC MALIGNANT LESIONS.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 112. ISSUE 31. P. 9710 -9715 36 65% 1
3 SHU, NS , CHUNG, MS , YAO, L , AN, M , QIANG, W , (2015) RESIDUE-SPECIFIC STRUCTURES AND MEMBRANE LOCATIONS OF PH-LOW INSERTION PEPTIDE BY SOLID-STATE NUCLEAR MAGNETIC RESONANCE.NATURE COMMUNICATIONS. VOL. 6. ISSUE . P. - 34 68% 0
4 ANDREEV, OA , ENGELMAN, DM , RESHETNYAK, YK , (2014) TARGETING DISEASED TISSUES BY PHLIP INSERTION AT LOW CELL SURFACE PH.FRONTIERS IN PHYSIOLOGY. VOL. 5. ISSUE . P. - 31 61% 3
5 ONYANGO, JO , CHUNG, MS , ENG, CH , KLEES, LM , LANGENBACHER, R , YAO, L , AN, M , (2015) NONCANONICAL AMINO ACIDS TO IMPROVE THE PH RESPONSE OF PHLIP INSERTION AT TUMOR ACIDITY.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 54. ISSUE 12. P. 3658 -3663 25 58% 14
6 DEACON, JC , ENGELMAN, DM , BARRERA, FN , (2015) TARGETING ACIDITY IN DISEASED TISSUES: MECHANISM AND APPLICATIONS OF THE MEMBRANE-INSERTING PEPTIDE, PHLIP.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 565. ISSUE . P. 40 -48 36 43% 4
7 HANZ, SZ , SHU, NS , QIAN, JN , CHRISTMAN, N , KRANZ, P , AN, M , GREWER, C , QIANG, W , (2016) PROTONATION-DRIVEN MEMBRANE INSERTION OF A PH-LOW INSERTION PEPTIDE.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 55. ISSUE 40. P. 12376 -12381 24 63% 0
8 ADOCHITE, RC , MOSHNIKOVA, A , GOLIJANIN, J , ANDREEV, OA , KATENKA, NV , RESHETNYAK, YK , (2016) COMPARATIVE STUDY OF TUMOR TARGETING AND BIODISTRIBUTION OF PH (LOW) INSERTION PEPTIDES (PHLIP(A (R)) PEPTIDES) CONJUGATED WITH DIFFERENT FLUORESCENT DYES.MOLECULAR IMAGING AND BIOLOGY. VOL. 18. ISSUE 5. P. 686 -696 22 69% 0
9 MCCARTY, MF , WHITAKER, J , (2010) MANIPULATING TUMOR ACIDIFICATION AS A CANCER TREATMENT STRATEGY.ALTERNATIVE MEDICINE REVIEW. VOL. 15. ISSUE 3. P. 264-272 36 40% 60
10 ANDERSON, M , MOSHNIKOVA, A , ENGELMAN, DM , RESHETNYAK, YK , ANDREEV, OA , (2016) PROBE FOR THE MEASUREMENT OF CELL SURFACE PH IN VIVO AND EX VIVO.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 113. ISSUE 29. P. 8177 -8181 24 52% 2

Classes with closest relation at Level 1


Rank Class id link
1 11789 INTERNATIONAL JOURNAL OF HYPERTHERMIA//STEP DOWN HEATING//HYPERTHERMIA
2 21252 EXTREME ACIDITY//PH SENSITIVE PROBE//DUAL RESPONSIVE RANGE
3 18052 CEST//CHEMICAL EXCHANGE SATURATION TRANSFER//CHEMICAL EXCHANGE SATURATION TRANSFER CEST
4 10481 INTERSTITIAL FLUID PRESSURE//EDWIN L STEELE//CANCER DETECTION AND TREATMENT
5 5745 P 31 MRS//NMR IN BIOMEDICINE//MAGNETIC RESONANCE IN MEDICINE
6 24339 LONIDAMINE//IONIDAMINE//ADVANCED BREAST CANCER CHEMOTHERAPY
7 1966 NA H EXCHANGER//SODIUM HYDROGEN EXCHANGER//NHE1
8 2109 CARBOGEN//TUMOR HYPOXIA//TUMOR OXYGENATION
9 1742 INTERNATIONAL JOURNAL OF HYPERTHERMIA//HYPERTHERMIA//SUPERFICIAL HYPERTHERMIA
10 17764 LYSOPHOSPHATIDYLCHOLINE//SPHINGOSYLPHOSPHORYLCHOLINE//GPR4

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