Class information for:
Level 1: ENZYMATIC PEPTIDE SYNTHESIS//ALPHA CHYMOTRYPSIN//ORGANIC SOLVENTS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3307 2015 29.1 64%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
239 3       LIPASE//JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC//BIOCATALYSIS 47598
647 2             LIPASE//PENICILLIN ACYLASE//IMMOBILIZATION 13621
3307 1                   ENZYMATIC PEPTIDE SYNTHESIS//ALPHA CHYMOTRYPSIN//ORGANIC SOLVENTS 2015

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENZYMATIC PEPTIDE SYNTHESIS authKW 970354 4% 82% 78
2 ALPHA CHYMOTRYPSIN authKW 344312 5% 24% 95
3 ORGANIC SOLVENTS authKW 334963 11% 10% 219
4 NONAQUEOUS ENZYMOLOGY authKW 272717 1% 60% 30
5 PEPTIDE SYNTHESIS authKW 260845 7% 13% 131
6 ASPARTAME PRECURSOR authKW 228173 1% 94% 16
7 SUBTILISIN CARLSBERG authKW 206589 1% 45% 30
8 INVERSE SUBSTRATE authKW 174692 1% 82% 14
9 UNIT ENZYMOL PROT FOLDING address 168411 1% 65% 17
10 FROZEN AQUEOUS SYSTEM authKW 136370 0% 100% 9

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biotechnology & Applied Microbiology 13461 35% 0% 704
2 Biochemistry & Molecular Biology 3459 36% 0% 731
3 Chemistry, Organic 1546 14% 0% 279
4 Chemistry, Multidisciplinary 971 17% 0% 336
5 Biophysics 398 6% 0% 124
6 Food Science & Technology 178 5% 0% 92
7 Chemistry, Medicinal 155 3% 0% 68
8 Biochemical Research Methods 152 4% 0% 78
9 Engineering, Chemical 129 5% 0% 97
10 Chemistry, Physical 98 8% 0% 162

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNIT ENZYMOL PROT FOLDING 168411 1% 65% 17
2 HUMACAO 80807 0% 67% 8
3 BIOSCI PHARM PSYCHOL 52600 1% 12% 30
4 FOOD BIOTECHNOL ENZYMOL 45457 0% 100% 3
5 ENZYME TEAM 41150 1% 23% 12
6 UNIT AGRARIAN SCI TECHNOL 30305 0% 100% 2
7 CUH STN 22266 0% 15% 10
8 AARSTR 1 15152 0% 100% 1
9 ADV MAT TECH DEV GURO KU 15152 0% 100% 1
10 AFSG BIOBASED PROD 15152 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOTECHNOLOGY AND BIOENGINEERING 34743 8% 1% 164
2 BIOCATALYSIS AND BIOTRANSFORMATION 23814 2% 4% 38
3 ENZYME AND MICROBIAL TECHNOLOGY 19254 4% 1% 87
4 BIOCATALYSIS 15132 1% 9% 11
5 JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC 14860 3% 2% 58
6 BIOTECHNOLOGY LETTERS 14844 5% 1% 96
7 INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 9142 2% 2% 39
8 BIOORGANICHESKAYA KHIMIYA 8533 2% 1% 43
9 BIOTECHNOLOGY TECHNIQUES 8048 1% 2% 28
10 BIOMEDICA BIOCHIMICA ACTA 5325 1% 1% 27

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ENZYMATIC PEPTIDE SYNTHESIS 970354 4% 82% 78 Search ENZYMATIC+PEPTIDE+SYNTHESIS Search ENZYMATIC+PEPTIDE+SYNTHESIS
2 ALPHA CHYMOTRYPSIN 344312 5% 24% 95 Search ALPHA+CHYMOTRYPSIN Search ALPHA+CHYMOTRYPSIN
3 ORGANIC SOLVENTS 334963 11% 10% 219 Search ORGANIC+SOLVENTS Search ORGANIC+SOLVENTS
4 NONAQUEOUS ENZYMOLOGY 272717 1% 60% 30 Search NONAQUEOUS+ENZYMOLOGY Search NONAQUEOUS+ENZYMOLOGY
5 PEPTIDE SYNTHESIS 260845 7% 13% 131 Search PEPTIDE+SYNTHESIS Search PEPTIDE+SYNTHESIS
6 ASPARTAME PRECURSOR 228173 1% 94% 16 Search ASPARTAME+PRECURSOR Search ASPARTAME+PRECURSOR
7 SUBTILISIN CARLSBERG 206589 1% 45% 30 Search SUBTILISIN+CARLSBERG Search SUBTILISIN+CARLSBERG
8 INVERSE SUBSTRATE 174692 1% 82% 14 Search INVERSE+SUBSTRATE Search INVERSE+SUBSTRATE
9 FROZEN AQUEOUS SYSTEM 136370 0% 100% 9 Search FROZEN+AQUEOUS+SYSTEM Search FROZEN+AQUEOUS+SYSTEM
10 PROTEASE CATALYZED PEPTIDE SYNTHESIS 136370 0% 100% 9 Search PROTEASE+CATALYZED+PEPTIDE+SYNTHESIS Search PROTEASE+CATALYZED+PEPTIDE+SYNTHESIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BORDUSA, F , (2002) PROTEASES IN ORGANIC SYNTHESIS.CHEMICAL REVIEWS. VOL. 102. ISSUE 12. P. 4817 -4867 209 44% 191
2 TAI, DF , (2003) ENZYMATIC PEPTIDE SYNTHESIS: FROM THE SUBSTRATE POINT OF VIEW.CURRENT ORGANIC CHEMISTRY. VOL. 7. ISSUE 6. P. 515-554 112 87% 11
3 KLIBANOV, AM , (2001) IMPROVING ENZYMES BY USING THEM IN ORGANIC SOLVENTS.NATURE. VOL. 409. ISSUE 6817. P. 241 -246 43 66% 1152
4 LOMBARD, C , SAULNIER, J , WALLACH, JM , (2005) RECENT TRENDS IN PROTEASE-CATALYZED PEPTIDE SYNTHESIS.PROTEIN AND PEPTIDE LETTERS. VOL. 12. ISSUE 7. P. 621-629 68 72% 45
5 GUZMAN, F , BARBERIS, S , ILLANES, A , (2007) PEPTIDE SYNTHESIS: CHEMICAL OR ENZYMATIC.ELECTRONIC JOURNAL OF BIOTECHNOLOGY. VOL. 10. ISSUE 2. P. 279 -314 103 42% 72
6 MURAKAMI, Y , HIRATA, A , (1998) ENZYMATIC SYNTHESIS OF PEPTIDES - REVIEW.SEIBUTSU-KOGAKU KAISHI. VOL. 76. ISSUE 6. P. 238 -254 109 56% 12
7 KUMAR, D , BHALLA, TC , (2005) MICROBIAL PROTEASES IN PEPTIDE SYNTHESIS: APPROACHES AND APPLICATIONS.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 68. ISSUE 6. P. 726-736 54 68% 71
8 VOSSENBERG, P , BEEFTINK, HH , STUART, MAC , TRAMPER, J , (2013) PROCESS DESIGN FOR ENZYMATIC PEPTIDE SYNTHESIS IN NEAR-ANHYDROUS ORGANIC MEDIA.BIOCATALYSIS AND BIOTRANSFORMATION. VOL. 31. ISSUE 5. P. 255 -268 48 63% 2
9 HEIDUSCHKA, P , DITTRICH, J , BARTH, A , (1990) ENZYMATIC-SYNTHESIS OF PEPTIDES - A SURVEY.PHARMAZIE. VOL. 45. ISSUE 3. P. 164-173 88 73% 7
10 TRAMPER, J , VOSSENBERG, P , BEEFTINK, HH , NUIJENS, T , STUART, MAC , (2012) SELECTING OPTIMAL CONDITIONS FOR ALCALASE CLEA-OM FOR SYNTHESIS OF DIPEPTIDES IN ORGANIC MEDIA.JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC. VOL. 75. ISSUE . P. 43 -49 30 97% 6

Classes with closest relation at Level 1


Rank Class id link
1 33199 SOLID GAS BIOREACTOR//SOLID GAS BIOFILTER//SOLID GAS PHASE
2 937 LIPASE//IMMOBILIZED LIPASE//CANDIDA RUGOSA LIPASE
3 988 KINETIC RESOLUTION//DYNAMIC KINETIC RESOLUTION//LIPASE
4 25142 TOFUYO//CARLSBERG RESEARCH COMMUNICATIONS//SERINE CARBOXYPEPTIDASE
5 24940 CROSS LINKED ENZYME AGGREGATES//CROSS LINKED ENZYME AGGREGATES CLEAS//FERMENTAT ENGN HEBEI
6 15009 BIOQUIM BIOL MOL INMUNOL B//IONIC LIQUID//KOSMOTROPICITY
7 24068 ARGINASE IMMOBILIZED//HYDRAULIC FRACTURE CLEANUP//IST PRINCIPI INGN CHIM
8 36423 HIP COMPLEX//HYDROPHOBIC ION PAIRING COMPLEX//ADJUSTABLE RELEASE RATE
9 21813 THERMOLYSIN//NEUTRAL PROTEASE//HALOPHILICITY
10 5838 REVERSE MICELLES//REVERSED MICELLES//AOT

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