Class information for:
Level 1: N SUCCINYL CHITOSAN//DEXTRAN PRODRUGS//BIOPHARMACEUT DRUG METAB

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
21790 405 30.8 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
12 4 POLYMER SCIENCE//MATERIALS SCIENCE, PAPER & WOOD//CHEMISTRY, PHYSICAL 1084170
41 3       INTERNATIONAL JOURNAL OF PHARMACEUTICS//DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY//PHARMACOLOGY & PHARMACY 99449
147 2             SOLID LIPID NANOPARTICLES//POLYMERIC MICELLES//LIPOSOMES 23275
21790 1                   N SUCCINYL CHITOSAN//DEXTRAN PRODRUGS//BIOPHARMACEUT DRUG METAB 405

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 N SUCCINYL CHITOSAN authKW 715489 5% 43% 22
2 DEXTRAN PRODRUGS authKW 527766 2% 100% 7
3 BIOPHARMACEUT DRUG METAB address 431227 8% 18% 31
4 LACTOSAMINATED N SUCCINYL CHITOSAN authKW 376976 1% 100% 5
5 DRUG DELIVERY address 371876 19% 6% 78
6 HEPATIC TARGETING authKW 279229 2% 37% 10
7 MACROMOLECULAR CONJUGATE authKW 241263 1% 80% 4
8 DEXTRAN METHYLPREDNISOLONE CONJUGATE authKW 226185 1% 100% 3
9 TISSUE ISOLATED TUMOR authKW 226185 1% 100% 3
10 6 O CARBOXYMETHYL CHITIN authKW 169637 1% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 4418 60% 0% 244
2 Chemistry, Medicinal 754 13% 0% 54
3 Chemistry, Multidisciplinary 645 27% 0% 111
4 Transplantation 502 8% 0% 31
5 Immunology 60 8% 0% 31
6 Surgery 49 8% 0% 33
7 Materials Science, Biomaterials 44 2% 0% 8
8 Oncology 18 6% 0% 23
9 Polymer Science 8 3% 0% 12
10 Multidisciplinary Sciences 7 1% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOPHARMACEUT DRUG METAB 431227 8% 18% 31
2 DRUG DELIVERY 371876 19% 6% 78
3 BASIC PHARMACEUT 109661 1% 36% 4
4 YOSHIDA SHIMOADACHI CHO 104708 1% 28% 5
5 EXPLORAT S 523 TOKODAI 75395 0% 100% 1
6 FRONT MED SCI 75395 0% 100% 1
7 ND 20 75395 0% 100% 1
8 ONKOLOG ZENTRUM 3 75395 0% 100% 1
9 OPPOSITE J L NEHRU AGR 75395 0% 100% 1
10 PHAM 75395 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CONTROLLED RELEASE 9111 7% 0% 30
2 JOURNAL OF DRUG TARGETING 8179 3% 1% 13
3 BIOLOGICAL & PHARMACEUTICAL BULLETIN 6378 7% 0% 27
4 PHARMACEUTICAL RESEARCH 4543 5% 0% 22
5 INTERNATIONAL JOURNAL OF PHARMACEUTICS 3978 7% 0% 29
6 CHEMICAL & PHARMACEUTICAL BULLETIN 2289 6% 0% 23
7 JOURNAL OF PHARMACEUTICAL SCIENCES 2159 4% 0% 18
8 DRUG DELIVERY 1444 1% 0% 5
9 REVUE CANADIENNE DE BIOLOGIE EXPERIMENTALE 1255 0% 2% 1
10 JOURNAL OF PHARMACOBIO-DYNAMICS 1149 1% 0% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 N SUCCINYL CHITOSAN 715489 5% 43% 22 Search N+SUCCINYL+CHITOSAN Search N+SUCCINYL+CHITOSAN
2 DEXTRAN PRODRUGS 527766 2% 100% 7 Search DEXTRAN+PRODRUGS Search DEXTRAN+PRODRUGS
3 LACTOSAMINATED N SUCCINYL CHITOSAN 376976 1% 100% 5 Search LACTOSAMINATED+N+SUCCINYL+CHITOSAN Search LACTOSAMINATED+N+SUCCINYL+CHITOSAN
4 HEPATIC TARGETING 279229 2% 37% 10 Search HEPATIC+TARGETING Search HEPATIC+TARGETING
5 MACROMOLECULAR CONJUGATE 241263 1% 80% 4 Search MACROMOLECULAR+CONJUGATE Search MACROMOLECULAR+CONJUGATE
6 DEXTRAN METHYLPREDNISOLONE CONJUGATE 226185 1% 100% 3 Search DEXTRAN+METHYLPREDNISOLONE+CONJUGATE Search DEXTRAN+METHYLPREDNISOLONE+CONJUGATE
7 TISSUE ISOLATED TUMOR 226185 1% 100% 3 Search TISSUE+ISOLATED+TUMOR Search TISSUE+ISOLATED+TUMOR
8 6 O CARBOXYMETHYL CHITIN 169637 1% 75% 3 Search 6+O+CARBOXYMETHYL+CHITIN Search 6+O+CARBOXYMETHYL+CHITIN
9 BIODISPOSITION 159652 1% 35% 6 Search BIODISPOSITION Search BIODISPOSITION
10 ANTITUMOR CHARACTERISTICS 150790 0% 100% 2 Search ANTITUMOR+CHARACTERISTICS Search ANTITUMOR+CHARACTERISTICS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KATO, Y , ONISHI, H , MACHIDA, Y , (2004) N-SUCCINYL-CHITOSAN AS A DRUG CARRIER: WATER-INSOLUBLE AND WATER-SOLUBLE CONJUGATES.BIOMATERIALS. VOL. 25. ISSUE 5. P. 907-915 26 59% 81
2 TAKAKURA, Y , (1996) DEVELOPMENT OF DRUG DELIVERY SYSTEMS FOR MACROMOLECULAR DRUGS.YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN. VOL. 116. ISSUE 7. P. 519 -532 32 70% 6
3 HASHIDA, M , NISHIKAWA, M , TAKAKURA, Y , (1995) HEPATIC TARGETING OF DRUGS AND PROTEINS BY CHEMICAL MODIFICATION.JOURNAL OF CONTROLLED RELEASE. VOL. 36. ISSUE 1-2. P. 99-107 19 83% 22
4 ISHIKI, N , ONISHI, H , MACHIDA, Y , (1997) BIOLOGICAL PROPERTIES OF CONJUGATES OF MITOMYCIN C WITH ESTRADIOL BENZOATE AND ESTRADIOL: THEIR STABILITY CHARACTERISTICS IN BIOLOGICAL MEDIA AND THEIR BINDING ABILITIES TO ESTROGEN RECEPTOR.BIOLOGICAL & PHARMACEUTICAL BULLETIN. VOL. 20. ISSUE 10. P. 1096 -1102 17 85% 9
5 TAKAKURA, Y , MAHATO, RI , HASHIDA, M , (1998) EXTRAVASATION OF MACROMOLECULES.ADVANCED DRUG DELIVERY REVIEWS. VOL. 34. ISSUE 1. P. 93 -108 29 43% 78
6 MEHVAR, R , (2000) DEXTRANS FOR TARGETED AND SUSTAINED DELIVERY OF THERAPEUTIC AND IMAGING AGENTS.JOURNAL OF CONTROLLED RELEASE. VOL. 69. ISSUE 1. P. 1 -25 33 29% 230
7 ZHANG, XP , MEHVAR, R , (2001) DEXTRAN-METHYLPREDNISOLONE SUCCINATE AS A PRODRUG OF METHYLPREDNISOLONE: PLASMA AND TISSUE DISPOSITION.JOURNAL OF PHARMACEUTICAL SCIENCES. VOL. 90. ISSUE 12. P. 2078-2087 19 61% 15
8 NISHIKAWA, M , TAKAKURA, Y , HASHIDA, M , (1996) PHARMACOKINETIC EVALUATION OF POLYMERIC CARRIERS.ADVANCED DRUG DELIVERY REVIEWS. VOL. 21. ISSUE 2. P. 135-155 36 35% 45
9 NISHIKAWA, M , (2005) DEVELOPMENT OF CELL-SPECIFIC TARGETING SYSTEMS FOR DRUGS AND GENES.BIOLOGICAL & PHARMACEUTICAL BULLETIN. VOL. 28. ISSUE 2. P. 195 -200 22 42% 24
10 NISHIKAWA, M , HASHIDA, M , TAKAKURA, Y , (2009) CATALASE DELIVERY FOR INHIBITING ROS-MEDIATED TISSUE INJURY AND TUMOR METASTASIS.ADVANCED DRUG DELIVERY REVIEWS. VOL. 61. ISSUE 4. P. 319-326 31 24% 62

Classes with closest relation at Level 1


Rank Class id link
1 36948 NANOMED TAIWAN//PRONECTIN//ENHANCED GENE EXPRESSION
2 26433 6 MALEIMIDOCAPROYLHYDRAZONE DERIVATIVE OF DOXORUBICIN//METHOTREXATE ALBUMIN//256 CARCINOSARCOMA WALKER
3 8461 HPMA COPOLYMER//POLYMER THER EUT//HPMA
4 25277 ORGOTEIN//ENDOGENOUS ANTIOXIDANT DEFENCE//LECITHINIZED SUPEROXIDE DISMUTASE PC SOD
5 36748 1 2 3 THIADIAZOLE 4 CARBOXYLIC ACID//BOVINE PANCREATIC PROTEINASE INHIBITOR//CAPTURE COMPETITION ELISA
6 18419 LIPID MICROSPHERES//O W LIPID EMULSION//SUBMICRON EMULSION
7 26135 LYMPHATIC TARGETING//ACTIVATED CARBON PARTICLES//BIOMED ENGN CANC
8 27341 ENZYME TECHNOL GRP//MODIFIED ENZYME//BIOTECHNOL STUDIES
9 7576 ASIALOGLYCOPROTEIN RECEPTOR//ASGPR//ASIALOGLYCOPROTEIN RECEPTOR ASGPR
10 13198 PRODRUG//DIFFUSION CELL EXPERIMENTS//DERMAL PRODRUG

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