Class information for:
Level 2: BLOOD SUBSTITUTES//ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY//HEMOGLOBIN BASED OXYGEN CARRIER

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2593 3632 31.4 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
519 3       BLOOD SUBSTITUTES//NEUROGLOBIN//HEMOGLOBIN 20769
2593 2             BLOOD SUBSTITUTES//ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY//HEMOGLOBIN BASED OXYGEN CARRIER 3632
2052 1                   BLOOD SUBSTITUTES//HEMOGLOBIN BASED OXYGEN CARRIER//ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY 2372
12550 1                   PERFLUOROCHEMICAL EMULSION//BIOMATERIALS ARTIFICIAL CELLS AND ARTIFICIAL ORGANS//FLUOSOL 897
27321 1                   CHIMERIC LIPOSOMES//ELECT TRAUMA//ADVANCED DRUG DELIVERY NANO SYSTEMS ADDNSS 232
32974 1                   LIPOPROTEIN FRACTIONS AND SUBFRACTIONS//TRITON WR 1339 INDUCED HYPERLIPIDEMIC RATS//POLOXAMER 407 131

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BLOOD SUBSTITUTES authKW 2459788 10% 77% 381
2 ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY journal 785650 8% 34% 273
3 HEMOGLOBIN BASED OXYGEN CARRIER authKW 732083 3% 82% 106
4 ARTIFICIAL OXYGEN CARRIER authKW 436608 2% 84% 62
5 BIOMATERIALS ARTIFICIAL CELLS AND IMMOBILIZATION BIOTECHNOLOGY journal 419947 3% 45% 112
6 BIOMATERIALS ARTIFICIAL CELLS AND ARTIFICIAL ORGANS journal 304538 3% 38% 95
7 LIPOSOME ENCAPSULATED HEMOGLOBIN authKW 261526 1% 94% 33
8 DIASPIRIN CROSS LINKED HEMOGLOBIN authKW 236399 1% 94% 30
9 OXYGEN CARRIER authKW 174240 3% 22% 95
10 POLYHEMOGLOBIN authKW 169506 1% 92% 22

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Materials Science, Biomaterials 26328 14% 1% 516
2 Engineering, Biomedical 23472 20% 0% 742
3 Critical Care Medicine 4060 7% 0% 248
4 Biotechnology & Applied Microbiology 2433 12% 0% 443
5 Anesthesiology 1735 4% 0% 162
6 Hematology 1442 7% 0% 248
7 Peripheral Vascular Diseases 1220 6% 0% 221
8 Cardiac & Cardiovascular System 1014 8% 0% 283
9 Transplantation 888 4% 0% 132
10 Surgery 497 8% 0% 308

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEMATOL PHYSIOL 70022 1% 42% 20
2 ARTIFICIAL CELLS ORGANS 67255 1% 24% 33
3 BIOCHEM VASC BIOL 66566 1% 29% 27
4 BLOOD SUBSTITUTES 50433 0% 100% 6
5 ORTHOPED PLAST HAND SURG 37821 0% 75% 6
6 MARTIN LUTHER KING JR DREW MED 35021 0% 83% 5
7 HEMOGLOBIN THER EUT 30017 0% 71% 5
8 ION CHIRICUTA CANC 26896 0% 80% 4
9 ELECT TRAUMA 25216 0% 100% 3
10 FORMULAT TOXICOL 25216 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY 785650 8% 34% 273
2 BIOMATERIALS ARTIFICIAL CELLS AND IMMOBILIZATION BIOTECHNOLOGY 419947 3% 45% 112
3 BIOMATERIALS ARTIFICIAL CELLS AND ARTIFICIAL ORGANS 304538 3% 38% 95
4 ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY 123505 1% 35% 42
5 ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY 23905 1% 8% 37
6 ARTIFICIAL ORGANS 10606 2% 2% 75
7 SHOCK 4249 1% 1% 45
8 INTERNATIONAL ANESTHESIOLOGY CLINICS 3487 0% 2% 17
9 JOURNAL OF LABORATORY AND CLINICAL MEDICINE 3455 1% 1% 41
10 CRITICAL CARE MEDICINE 3317 2% 1% 69

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BLOOD SUBSTITUTES 2459788 10% 77% 381 Search BLOOD+SUBSTITUTES Search BLOOD+SUBSTITUTES
2 HEMOGLOBIN BASED OXYGEN CARRIER 732083 3% 82% 106 Search HEMOGLOBIN+BASED+OXYGEN+CARRIER Search HEMOGLOBIN+BASED+OXYGEN+CARRIER
3 ARTIFICIAL OXYGEN CARRIER 436608 2% 84% 62 Search ARTIFICIAL+OXYGEN+CARRIER Search ARTIFICIAL+OXYGEN+CARRIER
4 LIPOSOME ENCAPSULATED HEMOGLOBIN 261526 1% 94% 33 Search LIPOSOME+ENCAPSULATED+HEMOGLOBIN Search LIPOSOME+ENCAPSULATED+HEMOGLOBIN
5 DIASPIRIN CROSS LINKED HEMOGLOBIN 236399 1% 94% 30 Search DIASPIRIN+CROSS+LINKED+HEMOGLOBIN Search DIASPIRIN+CROSS+LINKED+HEMOGLOBIN
6 OXYGEN CARRIER 174240 3% 22% 95 Search OXYGEN+CARRIER Search OXYGEN+CARRIER
7 POLYHEMOGLOBIN 169506 1% 92% 22 Search POLYHEMOGLOBIN Search POLYHEMOGLOBIN
8 HEMOGLOBIN SOLUTIONS 169455 1% 81% 25 Search HEMOGLOBIN+SOLUTIONS Search HEMOGLOBIN+SOLUTIONS
9 HBOC 201 168489 1% 95% 21 Search HBOC+201 Search HBOC+201
10 OXYGEN THERAPEUTICS 154445 1% 88% 21 Search OXYGEN+THERAPEUTICS Search OXYGEN+THERAPEUTICS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RIESS, JG , (2001) OXYGEN CARRIERS ("BLOOD SUBSTITUTES") - RAISON D'ETRE, CHEMISTRY, AND SOME PHYSIOLOGY.CHEMICAL REVIEWS. VOL. 101. ISSUE 9. P. 2797 -2919 703 54% 417
2 WINSLOW, RM , (2000) ALPHA ALPHA-CROSSLINKED HEMOGLOBIN: WAS FAILURE PREDICTED BY PRECLINICAL TESTING?.VOX SANGUINIS. VOL. 79. ISSUE 1. P. 1 -20 105 86% 62
3 CABRALES, P , INTAGLIETTA, M , (2013) BLOOD SUBSTITUTES: EVOLUTION FROM NONCARRYING TO OXYGEN- AND GAS-CARRYING FLUIDS.ASAIO JOURNAL. VOL. 59. ISSUE 4. P. 337-354 113 53% 15
4 TSUCHIDA, E , SOU, K , NAKAGAWA, A , SAKAI, H , KOMATSU, T , KOBAYASHI, K , (2009) ARTIFICIAL OXYGEN CARRIERS, HEMOGLOBIN VESICLES AND ALBUMIN-HEMES, BASED ON BIOCONJUGATE CHEMISTRY.BIOCONJUGATE CHEMISTRY. VOL. 20. ISSUE 8. P. 1419-1440 94 63% 66
5 SAKAI, H , SOU, K , TSUCHIDA, E , (2009) HEMOGLOBIN-VESICLES AS AN ARTIFICIAL OXYGEN CARRIER.METHODS IN ENZYMOLOGY LIPOSOMES, PT G. VOL. 465. ISSUE . P. 363-384 78 85% 8
6 CRETEUR, J , VINCENT, JL , (2003) HEMOGLOBIN SOLUTIONS.CRITICAL CARE MEDICINE. VOL. 31. ISSUE 12. P. S698-S707 88 86% 23
7 SPAHN, DR , KOCIAN, R , (2005) ARTIFICAL O-2 CARRIERS: STATUS IN 2005.CURRENT PHARMACEUTICAL DESIGN. VOL. 11. ISSUE 31. P. 4099-4114 107 64% 43
8 BUEHLER, PW , ALAYASH, AI , (2004) TOXICITIES OF HEMOGLOBIN SOLUTIONS: IN SEARCH OF IN-VITRO AND IN-VIVO MODEL SYSTEMS.TRANSFUSION. VOL. 44. ISSUE 10. P. 1516-1530 91 75% 55
9 KIM, JH , LEE, KY , (2009) CURRENT STATUS AND FUTURE OF ARTIFICIAL BLOOD - FOCUSING ON RED BLOOD CELL SUBSTITUTES.JOURNAL OF THE KOREAN MEDICAL ASSOCIATION. VOL. 52. ISSUE 2. P. 168 -181 67 92% 0
10 CRETEUR, J , VINCENT, JL , (2009) POTENTIAL USES OF HEMOGLOBIN-BASED OXYGEN CARRIERS IN CRITICAL CARE MEDICINE.CRITICAL CARE CLINICS. VOL. 25. ISSUE 2. P. 311-+ 69 83% 11

Classes with closest relation at Level 2


Rank Class id link
1 2756 ANGIOGENESIS GRP//RSR13//OXYGEN TRANSPORT
2 1479 NEUROGLOBIN//CYTOGLOBIN//HEMOGLOBIN
3 2393 FLUOROPOLYMERS//JOURNAL OF FLUORINE CHEMISTRY//FLUOROUS
4 1784 CLINICAL HEMORHEOLOGY//CLINICAL HEMORHEOLOGY AND MICROCIRCULATION//HEMORHEOLOGY
5 1246 HEMORRHAGIC SHOCK//HYPERTONIC SALINE//BACTERIAL TRANSLOCATION
6 401 TRANSFUSION//VOX SANGUINIS//BLOOD TRANSFUSION
7 2337 AQUEOUS TWO PHASE SYSTEMS//PEGYLATION//AQUEOUS BIPHASIC SYSTEMS
8 1363 TIRAPAZAMINE//DT DIAPHORASE//BIOREDUCTIVE DRUGS
9 744 SEPSIS//SEPTIC SHOCK//HYDROXYETHYL STARCH
10 1642 SICKLE CELL DISEASE//SICKLE CELL ANEMIA//ACUTE CHEST SYNDROME

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