Class information for:
Level 1: LYSOSOME//OSMOTIC SENSITIVITY//CALPAIN CATHEPSIN HYPOTHESIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
18351 555 49.4 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
262 3       AUTOPHAGY//RESVERATROL//HISTONE DEACETYLASE INHIBITOR 44558
1128 2             AUTOPHAGY//BECLIN 1//LC3 9655
18351 1                   LYSOSOME//OSMOTIC SENSITIVITY//CALPAIN CATHEPSIN HYPOTHESIS 555

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LYSOSOME authKW 503916 33% 5% 182
2 OSMOTIC SENSITIVITY authKW 195609 1% 44% 8
3 CALPAIN CATHEPSIN HYPOTHESIS authKW 176054 1% 80% 4
4 LYSOSOMAL MEMBRANE PERMEABILIZATION authKW 170680 2% 28% 11
5 AUTOPHAGOCYTOSIS authKW 162353 2% 27% 11
6 LYSOSOME STABILITY authKW 123788 1% 75% 3
7 REDOX ACTIVE IRON authKW 122529 1% 32% 7
8 CATHEPSINS authKW 120379 6% 7% 31
9 DIVALENT POSITIVELY CHARGED ION authKW 110035 0% 100% 2
10 LATENCY LOSS authKW 110035 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 1447 43% 0% 241
2 Cell Biology 1419 27% 0% 149
3 Biophysics 225 8% 0% 46
4 Pathology 169 6% 0% 31
5 Oncology 135 10% 0% 56
6 Geriatrics & Gerontology 132 3% 0% 16
7 Endocrinology & Metabolism 104 6% 0% 36
8 Neurosciences 80 10% 0% 53
9 Physiology 46 4% 0% 23
10 Medicine, Research & Experimental 30 4% 0% 22

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEW BUSINESS CARE 804 110035 0% 100% 2
2 CELL DEATH METAB UNIT 82523 1% 50% 3
3 BIOL MED SGBM 73355 0% 67% 2
4 CHILDRENS DISEASES 3 73355 0% 67% 2
5 P MED UHL 73355 0% 67% 2
6 OPTOSIS 58552 3% 6% 19
7 ARBEITSGRP MED MOL BIOL 55018 0% 100% 1
8 BIOL MOL SERVER OCHOA INVESTHOSP OCTUBRE 55018 0% 100% 1
9 BIOPHYS CELL BIOPHYS 55018 0% 100% 1
10 CELL BIOLPATHOL CLINCTY COUNCIL OSTERGOTLAN 55018 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REDOX REPORT 7091 2% 1% 11
2 FREE RADICAL BIOLOGY AND MEDICINE 3978 5% 0% 25
3 PEZCOLLER FOUNDATION SYMPOSIA 3282 2% 1% 11
4 AUTOPHAGY 2307 1% 1% 8
5 VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY 2148 1% 1% 7
6 CELL DEATH AND DIFFERENTIATION 1394 2% 0% 9
7 ANTIOXIDANTS & REDOX SIGNALING 1130 1% 0% 8
8 ADVANCES IN ENZYME REGULATION 825 1% 1% 3
9 MARINE GEOTECHNOLOGY 653 0% 1% 1
10 ACTA PATHOLOGICA MICROBIOLOGICA ET IMMUNOLOGICA SCANDINAVICA SECTION A-PATHOLOGY 588 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LYSOSOME 503916 33% 5% 182 Search LYSOSOME Search LYSOSOME
2 OSMOTIC SENSITIVITY 195609 1% 44% 8 Search OSMOTIC+SENSITIVITY Search OSMOTIC+SENSITIVITY
3 CALPAIN CATHEPSIN HYPOTHESIS 176054 1% 80% 4 Search CALPAIN+CATHEPSIN+HYPOTHESIS Search CALPAIN+CATHEPSIN+HYPOTHESIS
4 LYSOSOMAL MEMBRANE PERMEABILIZATION 170680 2% 28% 11 Search LYSOSOMAL+MEMBRANE+PERMEABILIZATION Search LYSOSOMAL+MEMBRANE+PERMEABILIZATION
5 AUTOPHAGOCYTOSIS 162353 2% 27% 11 Search AUTOPHAGOCYTOSIS Search AUTOPHAGOCYTOSIS
6 LYSOSOME STABILITY 123788 1% 75% 3 Search LYSOSOME+STABILITY Search LYSOSOME+STABILITY
7 REDOX ACTIVE IRON 122529 1% 32% 7 Search REDOX+ACTIVE+IRON Search REDOX+ACTIVE+IRON
8 CATHEPSINS 120379 6% 7% 31 Search CATHEPSINS Search CATHEPSINS
9 DIVALENT POSITIVELY CHARGED ION 110035 0% 100% 2 Search DIVALENT+POSITIVELY+CHARGED+ION Search DIVALENT+POSITIVELY+CHARGED+ION
10 LATENCY LOSS 110035 0% 100% 2 Search LATENCY+LOSS Search LATENCY+LOSS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 AITS, S , JAATTELA, M , (2013) LYSOSOMAL CELL DEATH AT A GLANCE.JOURNAL OF CELL SCIENCE. VOL. 126. ISSUE 9. P. 1905-1912 69 58% 81
2 JOHANSSON, AC , APPELQVIST, H , NILSSON, C , KAGEDAL, K , ROBERG, K , OLLINGER, K , (2010) REGULATION OF APOPTOSIS-ASSOCIATED LYSOSOMAL MEMBRANE PERMEABILIZATION.APOPTOSIS. VOL. 15. ISSUE 5. P. 527 -540 76 54% 150
3 BOYA, P , KROEMER, G , (2008) LYSOSOMAL MEMBRANE PERMEABILIZATION IN CELL DEATH.ONCOGENE. VOL. 27. ISSUE 50. P. 6434 -6451 66 40% 425
4 GROTH-PEDERSEN, L , JAATTELA, M , (2013) COMBATING APOPTOSIS AND MULTIDRUG RESISTANT CANCERS BY TARGETING LYSOSOMES.CANCER LETTERS. VOL. 332. ISSUE 2. P. 265-274 54 57% 42
5 CONUS, S , SIMON, HU , (2008) CATHEPSINS: KEY MODULATORS OF CELL DEATH AND INFLAMMATORY RESPONSES.BIOCHEMICAL PHARMACOLOGY. VOL. 76. ISSUE 11. P. 1374 -1382 57 60% 86
6 REPNIK, U , STOKA, V , TURK, V , TURK, B , (2012) LYSOSOMES AND LYSOSOMAL CATHEPSINS IN CELL DEATH.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1824. ISSUE 1. P. 22 -33 59 36% 120
7 GUICCIARDI, ME , LEIST, M , GORES, GJ , (2004) LYSOSOMES IN CELL DEATH.ONCOGENE. VOL. 23. ISSUE 16. P. 2881-2890 48 47% 391
8 YU, FF , CHEN, ZY , WANG, BL , JIN, Z , HOU, YF , MA, SM , LIU, XD , (2016) THE ROLE OF LYSOSOME IN CELL DEATH REGULATION.TUMOR BIOLOGY. VOL. 37. ISSUE 2. P. 1427 -1436 46 45% 1
9 REPNIK, U , CESEN, MH , TURK, B , (2014) LYSOSOMAL MEMBRANE PERMEABILIZATION IN CELL DEATH: CONCEPTS AND CHALLENGES.MITOCHONDRION. VOL. 19. ISSUE . P. 49 -57 45 40% 25
10 OBERLE, C , HUAI, J , REINHECKEL, T , TACKE, M , RASSNER, M , EKERT, PG , BUELLESBACH, J , BORNER, C , (2010) LYSOSOMAL MEMBRANE PERMEABILIZATION AND CATHEPSIN RELEASE IS A BAX/BAK-DEPENDENT, AMPLIFYING EVENT OF APOPTOSIS IN FIBROBLASTS AND MONOCYTES.CELL DEATH AND DIFFERENTIATION. VOL. 17. ISSUE 7. P. 1167-1178 30 68% 59

Classes with closest relation at Level 1


Rank Class id link
1 14530 CATHEPSIN D//PROCATHEPSIN D//UNITE HORMONES CANC
2 752 CATHEPSIN B//CYSTATIN//CATHEPSIN L
3 23712 MUCOLIPIDOSIS TYPE IV//MUCOLIPIN//MUCOLIPIDOSIS IV
4 26162 AUTOPHAGY//AUTOPHAGIC NEURON DEATH//BIOMFG BIOTECHNOL ENTERPRISE BRITE
5 18128 AGE PIGMENT//LIPOFUSCIN//ZAPRIONUS PARAVITTIGER
6 25040 APOPTOSIS INDUCING FACTOR//AIF//AMID
7 10004 NECROPTOSIS//RIP3//RIP1
8 37019 CATHEPSIN B LIKE PROTEINASE//SARCOPHAGA PEREGRINA//FAT BODY DECOMPOSITION
9 19319 DANON DISEASE//LAMP 2//LAMP 2 DEFICIENCY
10 29326 EYL LIPOSOMES//LYSOSOMOTROPIC AMINOESTERS//BIFUNCTIONAL QUATERNARY SALTS

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