Class information for:
Level 1: APOPTOSIS INDUCING FACTOR//AIF//AMID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
25040 293 45.9 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
441 3       TRAIL//SURVIVIN//APOPTOSIS 26474
306 2             TRAIL//SURVIVIN//APOPTOSIS 18497
25040 1                   APOPTOSIS INDUCING FACTOR//AIF//AMID 293

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 APOPTOSIS INDUCING FACTOR authKW 1488304 23% 22% 66
2 AIF authKW 728308 15% 16% 44
3 AMID authKW 234478 2% 38% 6
4 AIFM2 authKW 208432 1% 100% 2
5 MORT CELLULAIRE PROGRAMME PHYSIOPATHOL CELLULES address 208432 1% 100% 2
6 HARLEQUIN MICE authKW 138953 1% 67% 2
7 APOPTOSIS INDUCING FACTOR AIF authKW 134372 2% 18% 7
8 CASPASE INDEPENDENT authKW 106838 3% 11% 9
9 ACCAIF3 authKW 104216 0% 100% 1
10 AIF CYPA COMPLEX authKW 104216 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1400 36% 0% 105
2 Biochemistry & Molecular Biology 874 46% 0% 135
3 Biophysics 194 10% 0% 30
4 Neurosciences 112 14% 0% 40
5 Oncology 74 10% 0% 30
6 Medicine, Research & Experimental 45 6% 0% 17
7 Genetics & Heredity 27 5% 0% 16
8 Endocrinology & Metabolism 20 4% 0% 13
9 Pathology 15 3% 0% 8
10 Geriatrics & Gerontology 12 1% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MORT CELLULAIRE PROGRAMME PHYSIOPATHOL CELLULES 208432 1% 100% 2
2 ANIM VET OURCES 104216 0% 100% 1
3 ASSISANCE PUBL 104216 0% 100% 1
4 BASIC MED SCICORE IL RUMENT 104216 0% 100% 1
5 BIOACT MATBK PROGRAM 21 104216 0% 100% 1
6 BIOL SCI NEUROL NEUROL SCI 104216 0% 100% 1
7 BRAIN REPAIR REHAB 104216 0% 100% 1
8 BRANCH COURTS 104216 0% 100% 1
9 BRIAN INJURY REPAIR PROGRAM 104216 0% 100% 1
10 CARLO TA NEUROL FDN 104216 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL DEATH AND DIFFERENTIATION 4731 4% 0% 12
2 PEZCOLLER FOUNDATION SYMPOSIA 1850 2% 0% 6
3 ASN NEURO 463 0% 0% 1
4 ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY HEAD AND NECK SURGERY 447 0% 0% 1
5 CELL DEATH & DISEASE 393 1% 0% 3
6 ONCOGENE 357 3% 0% 8
7 DIGEST JOURNAL OF NANOMATERIALS AND BIOSTRUCTURES 297 1% 0% 2
8 FREE RADICAL BIOLOGY AND MEDICINE 295 2% 0% 5
9 EMBO JOURNAL 288 2% 0% 7
10 PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 263 1% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 APOPTOSIS INDUCING FACTOR 1488304 23% 22% 66 Search APOPTOSIS+INDUCING+FACTOR Search APOPTOSIS+INDUCING+FACTOR
2 AIF 728308 15% 16% 44 Search AIF Search AIF
3 AMID 234478 2% 38% 6 Search AMID Search AMID
4 AIFM2 208432 1% 100% 2 Search AIFM2 Search AIFM2
5 HARLEQUIN MICE 138953 1% 67% 2 Search HARLEQUIN+MICE Search HARLEQUIN+MICE
6 APOPTOSIS INDUCING FACTOR AIF 134372 2% 18% 7 Search APOPTOSIS+INDUCING+FACTOR+AIF Search APOPTOSIS+INDUCING+FACTOR+AIF
7 CASPASE INDEPENDENT 106838 3% 11% 9 Search CASPASE+INDEPENDENT Search CASPASE+INDEPENDENT
8 ACCAIF3 104216 0% 100% 1 Search ACCAIF3 Search ACCAIF3
9 AIF CYPA COMPLEX 104216 0% 100% 1 Search AIF+CYPA+COMPLEX Search AIF+CYPA+COMPLEX
10 AIF HOMOLOGOUS MITOCHONDRION ASSOCIATED INDUCER OF DEATH 104216 0% 100% 1 Search AIF+HOMOLOGOUS+MITOCHONDRION+ASSOCIATED+INDUCER+OF+DEATH Search AIF+HOMOLOGOUS+MITOCHONDRION+ASSOCIATED+INDUCER+OF+DEATH

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HANGEN, E , BLOMGREN, K , BENIT, P , KROEMER, G , MODJTAHEDI, N , (2010) LIFE WITH OR WITHOUT AIF.TRENDS IN BIOCHEMICAL SCIENCES. VOL. 35. ISSUE 5. P. 278-287 58 62% 57
2 FERREIRA, P , VILLANUEVA, R , CABON, L , SUSIN, SA , MEDINA, M , (2013) THE OXIDO-REDUCTASE ACTIVITY OF THE APOPTOSIS INDUCING FACTOR: A PROMISING PHARMACOLOGICAL TOOL?.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 14. P. 2628 -2636 50 56% 5
3 SEVRIOUKOVA, IF , (2011) APOPTOSIS-INDUCING FACTOR: STRUCTURE, FUNCTION, AND REDOX REGULATION.ANTIOXIDANTS & REDOX SIGNALING. VOL. 14. ISSUE 12. P. 2545-2578 76 31% 73
4 JOZA, N , POSPISILIK, JA , HANGEN, E , HANADA, T , MODJTAHEDI, N , PENNINGER, JM , KROEMER, G , (2009) AIF: NOT JUST AN APOPTOSIS-INDUCING FACTOR.NATURAL COMPOUNDS AND THEIR ROLE IN APOPTOTIC CELL SIGNALING PATHWAYS. VOL. 1171. ISSUE . P. 2-11 35 63% 81
5 DELAVALLEE, L , CABON, L , GALAN-MALO, P , LORENZO, HK , SUSIN, SA , (2011) AIF-MEDIATED CASPASE-INDEPENDENT NECROPTOSIS: A NEW CHANCE FOR TARGETED THERAPEUTICS.IUBMB LIFE. VOL. 63. ISSUE 4. P. 221 -232 44 42% 69
6 MODJTAHEDI, N , GIORDANETTO, F , MADEO, F , KROEMER, G , (2006) APOPTOSIS-INDUCING FACTOR: VITAL AND LETHAL.TRENDS IN CELL BIOLOGY. VOL. 16. ISSUE 5. P. 264 -272 35 54% 190
7 HANGEN, E , DE ZIO, D , BORDI, M , ZHU, C , DESSEN, P , CAFFIN, F , LACHKAR, S , PERFETTINI, JL , LAZAR, V , BENARD, J , ET AL (2010) A BRAIN-SPECIFIC ISOFORM OF MITOCHONDRIAL APOPTOSIS-INDUCING FACTOR: AIF2.CELL DEATH AND DIFFERENTIATION. VOL. 17. ISSUE 7. P. 1155-1166 26 84% 10
8 SORRENTINO, L , CALOGERO, AM , PANDINI, V , VANONI, MA , SEVRIOUKOVA, IF , ALIVERTI, A , (2015) KEY ROLE OF THE ADENYLATE MOIETY AND INTEGRITY OF THE ADENYLATE-BINDING SITE FOR THE NAD(+)/H BINDING TO MITOCHONDRIAL APOPTOSIS-INDUCING FACTOR.BIOCHEMISTRY. VOL. 54. ISSUE 47. P. 6996 -7009 30 64% 2
9 SEVRIOUKOVA, IF , (2016) STRUCTURE/FUNCTION RELATIONS IN AIFM1 VARIANTS ASSOCIATED WITH NEURODEGENERATIVE DISORDERS.JOURNAL OF MOLECULAR BIOLOGY. VOL. 428. ISSUE 18. P. 3650 -3665 22 73% 2
10 NORBERG, E , ORRENIUS, S , ZHIVOTOVSKY, B , (2010) MITOCHONDRIAL REGULATION OF CELL DEATH: PROCESSING OF APOPTOSIS-INDUCING FACTOR (AIF).BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 396. ISSUE 1. P. 95-100 28 51% 106

Classes with closest relation at Level 1


Rank Class id link
1 13732 DEOXYRIBONUCLEASE I//MED GENET BIOCHEM//L DNASE II
2 25856 BNIP3//BCH DOMAIN//HGTD P
3 9988 BCL 2//ROBERT S DOW NEUROBIOL S//EOSINOPHILIC NEURON
4 1845 APAF 1//CASPASE 2//CASPASE
5 10004 NECROPTOSIS//RIP3//RIP1
6 26299 EXERCISE PHYSIOL MUSCLE BIOL SARCOPENIA//MUSCLE CELL APOPTOSIS//ROBERT C BYRD HLTH SCI MUSCLE BIOL SARC
7 495 POLYADP RIBOSE POLYMERASE//POLYADP RIBOSE//POLYADP RIBOSYLATION
8 18351 LYSOSOME//OSMOTIC SENSITIVITY//CALPAIN CATHEPSIN HYPOTHESIS
9 33210 PARAPTOSIS//BAP31//AIP1 ALIX
10 21946 APOPTOSIS AND CEREBROVASCULAR INJURY//APOPTOSIS AND NEURODEGENERATION//BRAIN AGING DEMENTIA

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