Class information for:
Level 1: ELLIPTICINE//OLIVACINE//INTOPLICINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
17911 576 29.2 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
9 3       CHEMISTRY, ORGANIC//JOURNAL OF HETEROCYCLIC CHEMISTRY//KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII 135847
1235 2             INDOLE//BISINDOLYLMETHANES//ELLIPTICINE 9055
17911 1                   ELLIPTICINE//OLIVACINE//INTOPLICINE 576

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ELLIPTICINE authKW 2198435 13% 58% 72
2 OLIVACINE authKW 286255 2% 60% 9
3 INTOPLICINE authKW 238549 1% 75% 6
4 PYRIDOCARBAZOLE authKW 238549 1% 75% 6
5 S 16020 2 authKW 212046 1% 100% 4
6 1 SUBSTITUTED 6H PYRIDO4 3 BCARBAZOLE authKW 159035 1% 100% 3
7 RP 60475 authKW 159035 1% 100% 3
8 6H PYRIDO4 3 BCARBAZOLE authKW 106023 0% 100% 2
9 CELIPTIUM authKW 106023 0% 100% 2
10 DUAL TOPOISOMERASES I AND II INHIBITORS authKW 106023 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 1079 13% 0% 77
2 Pharmacology & Pharmacy 987 26% 0% 148
3 Oncology 808 21% 0% 120
4 Chemistry, Organic 273 11% 0% 65
5 Toxicology 236 7% 0% 39
6 Biochemistry & Molecular Biology 178 19% 0% 107
7 Biophysics 126 6% 0% 37
8 Crystallography 119 5% 0% 26
9 Chemistry, Multidisciplinary 76 10% 0% 60
10 Chemistry, Analytical 15 4% 0% 22

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NIHR HLTH PROTECT UNIT HLTH IMPACT ENVIRONM H 95418 1% 60% 3
2 PHYSIOL CELLULAIRE MOLEC CNRS URA 1180 70681 0% 67% 2
3 ANALYT ENVIRONM SCI 67444 2% 9% 14
4 1 RUE GUY DE LA BROSSE 53012 0% 100% 1
5 CEA DSM DRECAM SCM CNRS URA 331 53012 0% 100% 1
6 CHIM PHYS CNRS URA 400 45 RUE ST PE 53012 0% 100% 1
7 CNRSINC3MEA 4258FR 3038 53012 0% 100% 1
8 CQO 53012 0% 100% 1
9 CRLCC FRANCOIS BACLESSECJF INSERM 96 03 53012 0% 100% 1
10 CRLCC FRANCOIS BACLESSEUP EA 1772 53012 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTI-CANCER DRUG DESIGN 10209 2% 2% 11
2 NEUROENDOCRINOLOGY LETTERS 5357 3% 1% 17
3 BIOMEDICINE & PHARMACOTHERAPY 1908 2% 0% 12
4 EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY 1789 1% 0% 8
5 INVESTIGATIONAL NEW DRUGS 1668 2% 0% 9
6 BIOCHEMICAL PHARMACOLOGY 1487 4% 0% 23
7 CRYSTAL STRUCTURE COMMUNICATIONS 1192 1% 1% 4
8 JOURNAL OF MEDICINAL CHEMISTRY 1165 4% 0% 22
9 CANCER CHEMOTHERAPY AND PHARMACOLOGY 706 2% 0% 10
10 JOURNAL DE PHARMACOLOGIE 629 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ELLIPTICINE 2198435 13% 58% 72 Search ELLIPTICINE Search ELLIPTICINE
2 OLIVACINE 286255 2% 60% 9 Search OLIVACINE Search OLIVACINE
3 INTOPLICINE 238549 1% 75% 6 Search INTOPLICINE Search INTOPLICINE
4 PYRIDOCARBAZOLE 238549 1% 75% 6 Search PYRIDOCARBAZOLE Search PYRIDOCARBAZOLE
5 S 16020 2 212046 1% 100% 4 Search S+16020+2 Search S+16020+2
6 1 SUBSTITUTED 6H PYRIDO4 3 BCARBAZOLE 159035 1% 100% 3 Search 1+SUBSTITUTED+6H+PYRIDO4+3+BCARBAZOLE Search 1+SUBSTITUTED+6H+PYRIDO4+3+BCARBAZOLE
7 RP 60475 159035 1% 100% 3 Search RP+60475 Search RP+60475
8 6H PYRIDO4 3 BCARBAZOLE 106023 0% 100% 2 Search 6H+PYRIDO4+3+BCARBAZOLE Search 6H+PYRIDO4+3+BCARBAZOLE
9 CELIPTIUM 106023 0% 100% 2 Search CELIPTIUM Search CELIPTIUM
10 DUAL TOPOISOMERASES I AND II INHIBITORS 106023 0% 100% 2 Search DUAL+TOPOISOMERASES+I+AND+II+INHIBITORS Search DUAL+TOPOISOMERASES+I+AND+II+INHIBITORS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 FREI, E , STIBOROVA, M , (2014) ELLIPTICINES AS DNA-TARGETED CHEMOTHERAPEUTICS.CURRENT MEDICINAL CHEMISTRY. VOL. 21. ISSUE 5. P. 575 -591 74 49% 12
2 RYVOLOVA, M , ADAM, V , ECKSCHLAGER, T , STIBOROVA, M , KIZEK, R , (2012) STUDY OF DNA-ELLIPTICINE INTERACTION BY CAPILLARY ELECTROPHORESIS WITH LASER-INDUCED FLUORESCENCE DETECTION.ELECTROPHORESIS. VOL. 33. ISSUE 11. P. 1545-1549 32 86% 9
3 STIBOROVA, M , RUPERTOVA, M , FREI, E , (2011) CYTOCHROME P450-AND PEROXIDASE-MEDIATED OXIDATION OF ANTICANCER ALKALOID ELLIPTICINE DICTATES ITS ANTI-TUMOR EFFICIENCY.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1814. ISSUE 1. P. 175-185 49 49% 45
4 STIBOROVA, M , CERNA, V , MOSEROVA, M , MRIZOVA, I , ARLT, VM , FREI, E , (2015) THE ANTICANCER DRUG ELLIPTICINE ACTIVATED WITH CYTOCHROME P450 MEDIATES DNA DAMAGE DETERMINING ITS PHARMACOLOGICAL EFFICIENCIES: STUDIES WITH RATS, HEPATIC CYTOCHROME P450 REDUCTASE NULL (HRN (TM)) MICE AND PURE ENZYMES.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 16. ISSUE 1. P. 284 -306 47 53% 0
5 STIBOROVA, M , MANHARTOVA, Z , HODEK, P , ADAM, V , KIZEK, R , ECKSCHLAGER, T , FREI, E , (2015) CYTOTOXICITY OF AND DNA ADDUCT FORMATION BY ELLIPTICINE AND ITS MICELLAR FORM IN HUMAN LEUKEMIA CELLS IN VITRO.NEUROENDOCRINOLOGY LETTERS. VOL. 36. ISSUE . P. 22 -28 25 93% 0
6 STIBOROVA, M , POLJAKOVA, J , MRIZOVA, I , BOREK-DOHALSKA, L , ECKSCHLAGER, T , ADAM, V , KIZEK, R , FREI, E , (2014) EXPRESSION LEVELS OF ENZYMES METABOLIZING AN ANTICANCER DRUG ELLIPTICINE DETERMINED BY ELECTROMIGRATION ASSAYS INFLUENCE ITS CYTOTOXICITY TO CANCER CELLS - A COMPARATIVE STUDY.INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE. VOL. 9. ISSUE 10. P. 5675 -5689 28 80% 1
7 MARTINKOVA, E , DONTENWILL, M , FREI, E , STIBOROVA, M , (2009) CYTOTOXICITY OF AND DNA ADDUCT FORMATION BY ELLIPTICINE IN HUMAN U87MG GLIOBLASTOMA CANCER CELLS.NEUROENDOCRINOLOGY LETTERS. VOL. 30. ISSUE . P. 60 -66 29 74% 9
8 STIBOROVA, M , CERNA, V , MOSEROVA, M , ARLT, VM , FREI, E , (2013) THE EFFECT OF BENZO[A]PYRENE ON METABOLIC ACTIVATION OF ANTICANCER DRUG ELLIPTICINE IN MICE.NEUROENDOCRINOLOGY LETTERS. VOL. 34. ISSUE . P. 43-54 30 59% 0
9 POLJAKOVA, J , ECKSCHLAGER, T , CINATL, J , KIZEK, R , FREI, E , STIBOROVA, M , (2013) ELECTROCHEMICAL DETERMINATION OF ENZYMES METABOLIZING ELLIPTICINE IN THYROID CANCER CELLS - A TOOL TO EXPLAIN THE MECHANISM OF ELLIPTICINE TOXICITY TO THESE CELLS.INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE. VOL. 8. ISSUE 2. P. 1573-1585 22 76% 2
10 STIBOROVA, M , MANHARTOVA, Z , HODEK, P , ADAM, V , KIZEK, R , FREI, E , (2014) FORMATION OF DNA ADDUCTS BY ELLIPTICINE AND ITS MICELLAR FORM IN RATS - A COMPARATIVE STUDY.SENSORS. VOL. 14. ISSUE 12. P. 22982 -22997 27 55% 1

Classes with closest relation at Level 1


Rank Class id link
1 6456 CARBAZOLE ALKALOIDS//MURRAYA KOENIGII//CARBAZOLE ALKALOID
2 2662 TOPOISOMERASE II//DNA TOPOISOMERASE II//TOPOISOMERASE II ALPHA
3 36808 TAERIM CENT//PARA CHLORO META XYLENOL PCMX//4 CHLORO 3 5 DIMETHYLPHENOL PCMX
4 18080 CRYPTOLEPINE//CRYPTOLEPIS SANGUINOLENTA//INDOLOQUINOLINE
5 9157 SABARUBICIN//BARMINOMYCIN//ACTINOMYCIN
6 29974 CI 958//ARYLMETHYLAMINOPROPANEDIOLS//SR271425
7 24133 ALSTONINE//PB 100 ALKALOID//ELECTRONIC SPECTRA AT 298 K
8 36691 2 AMINOHYDROQUINONE//2 TRIFLUOROACETYLAMINOBENZOQUINONE//21H QUINOLYLIDENE
9 21112 PAULLONES//ADV BIOINFORMAT SYST MED//NCI 60
10 26774 ISOXAZOLONES//3 METHYL 4 ARYLMETHYLENE ISOXAZOL 54H ONES//PALMEROLIDE

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