Class information for:
Level 1: DIAMIDINES//PENTAMIDINE//AROMATIC DIAMIDINES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15591 703 31.2 68%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
326 3       LEISHMANIA//TRYPANOSOMA CRUZI//PARASITIOLOGY 38360
108 2             TRYPANOSOMA CRUZI//CHAGAS DISEASE//PARASITIOLOGY 25255
15591 1                   DIAMIDINES//PENTAMIDINE//AROMATIC DIAMIDINES 703

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIAMIDINES authKW 611678 4% 54% 26
2 PENTAMIDINE authKW 485236 7% 21% 52
3 AROMATIC DIAMIDINES authKW 310240 1% 71% 10
4 BISBENZAMIDINE authKW 260607 1% 100% 6
5 FURAMIDINE authKW 236473 1% 78% 7
6 PENTAMIDINE ANALOGS authKW 217172 1% 100% 5
7 BICHALCOPHENES authKW 173738 1% 100% 4
8 DB75 authKW 173738 1% 100% 4
9 ARYLIMIDAMIDES authKW 155120 1% 71% 5
10 N REDUCTION authKW 155120 1% 71% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 6198 28% 0% 197
2 Pharmacology & Pharmacy 2027 32% 0% 228
3 Chemistry, Organic 656 15% 0% 106
4 Microbiology 476 12% 0% 85
5 Parasitiology 301 4% 0% 30
6 Tropical Medicine 154 2% 0% 17
7 Chemistry, Multidisciplinary 153 12% 0% 87
8 Infectious Diseases 151 5% 0% 36
9 Toxicology 131 5% 0% 34
10 Biochemistry & Molecular Biology 38 11% 0% 77

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOTECHNOL DRUG DESIGN 121724 4% 9% 30
2 INSERMJPARCIMPRT IFR 114U837 86869 0% 100% 2
3 PROGRAMME MALAD TROP NEGLIGEES 86869 0% 100% 2
4 INTERDISCIPLINARY PROGRAMS FUNCT GENOM 57911 0% 67% 2
5 AIDS CLIN TRAILS UNIT 43434 0% 100% 1
6 BIOACT CPDS DEV LIDEBMED CHEM 43434 0% 100% 1
7 BIOCHEM TRYPS 43434 0% 100% 1
8 BIOL ERS EUKARYOT EMERGING PATHOGENS BDE 43434 0% 100% 1
9 BIOL STRUCT UNIT 43434 0% 100% 1
10 BIOS CHEM 43434 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 5308 8% 0% 54
2 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 5045 5% 0% 33
3 JOURNAL OF MEDICINAL CHEMISTRY 3357 6% 0% 41
4 ARCHIV DER PHARMAZIE 2893 2% 0% 17
5 HETEROCYCLIC COMMUNICATIONS 2209 1% 1% 9
6 DRUG METABOLISM AND DISPOSITION 1848 3% 0% 18
7 BIOORGANIC & MEDICINAL CHEMISTRY 1737 3% 0% 23
8 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1128 4% 0% 26
9 DRUG DESIGN DEVELOPMENT AND THERAPY 1118 1% 0% 6
10 ACS INFECTIOUS DISEASES 1036 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DIAMIDINES 611678 4% 54% 26 Search DIAMIDINES Search DIAMIDINES
2 PENTAMIDINE 485236 7% 21% 52 Search PENTAMIDINE Search PENTAMIDINE
3 AROMATIC DIAMIDINES 310240 1% 71% 10 Search AROMATIC+DIAMIDINES Search AROMATIC+DIAMIDINES
4 BISBENZAMIDINE 260607 1% 100% 6 Search BISBENZAMIDINE Search BISBENZAMIDINE
5 FURAMIDINE 236473 1% 78% 7 Search FURAMIDINE Search FURAMIDINE
6 PENTAMIDINE ANALOGS 217172 1% 100% 5 Search PENTAMIDINE+ANALOGS Search PENTAMIDINE+ANALOGS
7 BICHALCOPHENES 173738 1% 100% 4 Search BICHALCOPHENES Search BICHALCOPHENES
8 DB75 173738 1% 100% 4 Search DB75 Search DB75
9 ARYLIMIDAMIDES 155120 1% 71% 5 Search ARYLIMIDAMIDES Search ARYLIMIDAMIDES
10 N REDUCTION 155120 1% 71% 5 Search N+REDUCTION Search N+REDUCTION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SOEIRO, MNC , WERBOVETZ, K , BOYKIN, DW , WILSON, WD , WANG, MZ , HEMPHILL, A , (2013) NOVEL AMIDINES AND ANALOGUES AS PROMISING AGENTS AGAINST INTRACELLULAR PARASITES: A SYSTEMATIC REVIEW.PARASITOLOGY. VOL. 140. ISSUE 8. P. 929 -951 70 51% 25
2 PATRICK, DA , ISMAIL, MA , ARAFA, RK , WENZLER, T , ZHU, X , PANDHARKAR, T , JONES, SK , WERBOVETZ, KA , BRUN, R , BOYKIN, DW , ET AL (2013) SYNTHESIS AND ANTIPROTOZOAL ACTIVITY OF DICATIONIC M-TERPHENYL AND 1,3-DIPYRIDYLBENZENE DERIVATIVES.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 56. ISSUE 13. P. 5473 -5494 48 51% 11
3 BAKUNOVA, SM , BAKUNOV, SA , PATRICK, DA , KUMAR, EVKS , OHEMENG, KA , BRIDGES, AS , WENZLER, T , BARSZCZ, T , JONES, SK , WERBOVETZ, KA , ET AL (2009) STRUCTURE-ACTIVITY STUDY OF PENTAMIDINE ANALOGUES AS ANTIPROTOZOAL AGENTS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 52. ISSUE 7. P. 2016 -2035 53 49% 23
4 ISMAIL, MA , EL BIALY, SA , BRUN, R , WENZLER, T , NANJUNDA, R , WILSON, WD , BOYKIN, DW , (2011) DICATIONIC PHENYL-2,2 '-BICHALCOPHENES AND ANALOGUES AS ANTIPROTOZOAL AGENTS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 19. ISSUE 2. P. 978-984 28 85% 4
5 BOYKIN, DW , (2002) ANTIMICROBIAL ACTIVITY OF THE DNA MINOR GROOVE BINDERS FURAMIDINE AND ANALOGS.JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY. VOL. 13. ISSUE 6. P. 763-771 37 74% 20
6 WILSON, WD , TANIOUS, FA , MATHIS, A , TEVIS, D , HALL, JE , BOYKIN, DW , (2008) ANTIPARASITIC COMPOUNDS THAT TARGET DNA.BIOCHIMIE. VOL. 90. ISSUE 7. P. 999 -1014 37 52% 82
7 SOEIRO, MNC , DE SOUZA, EM , STEPHENS, CE , BOYKIN, DW , (2005) AROMATIC DIAMIDINES AS ANTIPARASITIC AGENTS.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 14. ISSUE 8. P. 957-972 55 40% 81
8 ARAFA, RK , WENZLER, T , BRUN, R , CHAI, Y , WILSON, WD , (2011) MOLECULAR MODELING STUDY AND SYNTHESIS OF NOVEL DICATIONIC FLEXIBLE TRIARYL GUANIDINES AND IMIDAMIDES AS ANTIPROTOZOAL AGENTS.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 46. ISSUE 12. P. 5852 -5860 26 76% 7
9 KOTTHAUS, J , KOTTHAUS, J , SCHADE, D , SCHWERING, U , HUNGELING, H , MULLER-FIELITZ, H , RAASCH, W , CLEMENT, B , (2011) NEW PRODRUGS OF THE ANTIPROTOZOAL DRUG PENTAMIDINE.CHEMMEDCHEM. VOL. 6. ISSUE 12. P. 2233 -2242 25 78% 8
10 HU, LX , PATEL, A , BONDADA, L , YANG, SY , WANG, MZ , MUNDE, M , WILSON, WD , WENZLER, T , BRUN, R , BOYKIN, DW , (2013) SYNTHESIS AND ANTIPROTOZOAL ACTIVITY OF DICATIONIC 2,6-DIPHENYLPYRAZINES AND AZA-ANALOGUES.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 21. ISSUE 21. P. 6732 -6741 25 74% 5

Classes with closest relation at Level 1


Rank Class id link
1 3208 MINOR GROOVE BINDER//DISTAMYCIN//PYRROLE IMIDAZOLE POLYAMIDE
2 6509 HUMAN AFRICAN TRYPANOSOMIASIS//TRYPANOSOMA BRUCEI GAMBIENSE//SLEEPING SICKNESS
3 454 PNEUMOCYSTIS CARINII//PNEUMOCYSTIS JIROVECII//PNEUMOCYSTIS PNEUMONIA
4 9995 BENZNIDAZOLE//NIFURTIMOX//TRYPANOSOMA CRUZI
5 18581 DRUG INDUCED PANCREATITIS//BILIARY STONE//DRUG INDUCED ACUTE PANCREATITIS
6 33515 DINITROANILINE//PHOSPHOROTHIOAMIDATE//2R 3S N BENZOYL 3 PHENYLISOSERINE
7 3390 LEISHMANIA//MILTEFOSINE//ANTIMONY RESISTANCE
8 15850 1 2 4 OXADIAZOLE//DIPARTIMENTO CHIM ORGAN E PATERNO//AMIDOXIME
9 31833 FK409//ANTITHROMBOTIC PROPERTIES//1 4 3 6 DIANHYDRO D SORBITOL 5 NITRATE
10 14339 SPERMIDINE SYNTHASE//S ADENOSYLMETHIONINE DECARBOXYLASE//AMINOPROPYLTRANSFERASE

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