Class information for:
Level 1: SPERMIDINE SYNTHASE//S ADENOSYLMETHIONINE DECARBOXYLASE//AMINOPROPYLTRANSFERASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14339 776 31.5 57%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
496 3       WHIPPLES DISEASE//POLYAMINES//TROPHERYMA WHIPPLEI 22789
1136 2             POLYAMINES//SPERMIDINE//PUTRESCINE 9579
14339 1                   SPERMIDINE SYNTHASE//S ADENOSYLMETHIONINE DECARBOXYLASE//AMINOPROPYLTRANSFERASE 776

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SPERMIDINE SYNTHASE authKW 354625 3% 35% 26
2 S ADENOSYLMETHIONINE DECARBOXYLASE authKW 157603 3% 16% 25
3 AMINOPROPYLTRANSFERASE authKW 128771 1% 55% 6
4 DECARBOXYLATED S ADENOSYLMETHIONINE authKW 125913 1% 80% 4
5 CATIONIC DIAMIDINES authKW 118045 0% 100% 3
6 DFMO RESISTANCE authKW 118045 0% 100% 3
7 S ADENOSYLMETHIONINE METABOLISM authKW 118045 0% 100% 3
8 SINEFUNGIN authKW 98356 1% 25% 10
9 TRANS 4 METHYLCYCLOHEXYLAMINE authKW 88532 0% 75% 3
10 CIENCIAS TECNOL DR CESAR MILSTEIN address 78697 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Parasitiology 4223 14% 0% 111
2 Biochemistry & Molecular Biology 2850 51% 0% 392
3 Tropical Medicine 902 5% 0% 41
4 Biophysics 311 8% 0% 64
5 Pharmacology & Pharmacy 279 13% 0% 104
6 Chemistry, Medicinal 228 6% 0% 45
7 Microbiology 179 8% 0% 60
8 Biochemical Research Methods 102 5% 0% 37
9 Chemistry, Organic 64 6% 0% 45
10 Cell Biology 45 6% 0% 47

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CIENCIAS TECNOL DR CESAR MILSTEIN 78697 0% 100% 2
2 HASKINS S INC 44964 1% 29% 4
3 BIOCHEM CHEMOTHER Y UNIT 39348 0% 100% 1
4 CENT ANIM HLTH DISCOVERY 39348 0% 100% 1
5 DISCOVER S 39348 0% 100% 1
6 ERWIN W MUELLER S 208 39348 0% 100% 1
7 FISOL FARMACOL TOXICOL CASTILLA LEON 39348 0% 100% 1
8 MACROPHAGES DEV IMMUN 39348 0% 100% 1
9 PHARM GALEN ADEN EA 3234 39348 0% 100% 1
10 PHARMACOL GYNECOL OBSTET PAEDIAT 39348 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADVANCES IN POLYAMINE RESEARCH 13846 1% 7% 5
2 MOLECULAR AND BIOCHEMICAL PARASITOLOGY 8937 5% 1% 36
3 EXPERIMENTAL PARASITOLOGY 3141 3% 0% 20
4 MEDICAL BIOLOGY 2649 1% 1% 5
5 TROPICAL MEDICINE AND PARASITOLOGY 2364 1% 1% 7
6 BIOCHEMICAL JOURNAL 1799 5% 0% 37
7 JOURNAL OF PROTOZOOLOGY 1634 1% 1% 8
8 BIOCHEMICAL PHARMACOLOGY 1515 3% 0% 27
9 TROPENMEDIZIN UND PARASITOLOGIE 1190 0% 1% 3
10 BIKEN JOURNAL 1052 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SPERMIDINE SYNTHASE 354625 3% 35% 26 Search SPERMIDINE+SYNTHASE Search SPERMIDINE+SYNTHASE
2 S ADENOSYLMETHIONINE DECARBOXYLASE 157603 3% 16% 25 Search S+ADENOSYLMETHIONINE+DECARBOXYLASE Search S+ADENOSYLMETHIONINE+DECARBOXYLASE
3 AMINOPROPYLTRANSFERASE 128771 1% 55% 6 Search AMINOPROPYLTRANSFERASE Search AMINOPROPYLTRANSFERASE
4 DECARBOXYLATED S ADENOSYLMETHIONINE 125913 1% 80% 4 Search DECARBOXYLATED+S+ADENOSYLMETHIONINE Search DECARBOXYLATED+S+ADENOSYLMETHIONINE
5 CATIONIC DIAMIDINES 118045 0% 100% 3 Search CATIONIC+DIAMIDINES Search CATIONIC+DIAMIDINES
6 DFMO RESISTANCE 118045 0% 100% 3 Search DFMO+RESISTANCE Search DFMO+RESISTANCE
7 S ADENOSYLMETHIONINE METABOLISM 118045 0% 100% 3 Search S+ADENOSYLMETHIONINE+METABOLISM Search S+ADENOSYLMETHIONINE+METABOLISM
8 SINEFUNGIN 98356 1% 25% 10 Search SINEFUNGIN Search SINEFUNGIN
9 TRANS 4 METHYLCYCLOHEXYLAMINE 88532 0% 75% 3 Search TRANS+4+METHYLCYCLOHEXYLAMINE Search TRANS+4+METHYLCYCLOHEXYLAMINE
10 HELIX DISORDER 78697 0% 100% 2 Search HELIX+DISORDER Search HELIX+DISORDER

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BIRKHOLTZ, LM , WILLIAMS, M , NIEMAND, J , LOUW, AI , PERSSON, L , HEBY, O , (2011) POLYAMINE HOMOEOSTASIS AS A DRUG TARGET IN PATHOGENIC PROTOZOA: PECULIARITIES AND POSSIBILITIES.BIOCHEMICAL JOURNAL. VOL. 438. ISSUE . P. 229 -244 77 57% 26
2 REGUERA, RM , TEKWANI, BL , BALANA-FOUCE, R , (2005) POLYAMINE TRANSPORT IN PARASITES: A POTENTIAL TARGET FOR NEW ANTIPARASITIC DRUG DEVELOPMENT.COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY. VOL. 140. ISSUE 2. P. 151 -164 61 50% 45
3 HEBY, O , PERSSON, L , RENTALA, M , (2007) TARGETING THE POLYAMINE BIOSYNTHETIC ENZYMES: A PROMISING APPROACH TO THERAPY OF AFRICAN SLEEPING SICKNESS, CHAGAS' DISEASE, AND LEISHMANIASIS.AMINO ACIDS. VOL. 33. ISSUE 2. P. 359-366 34 68% 95
4 MULLER, IB , DAS GUPTA, R , LUERSEN, K , WRENGER, C , WALTER, RD , (2008) ASSESSING THE POLYAMINE METABOLISM OF PLASMODIUM FALCIPARUM AS CHEMOTHERAPEUTIC TARGET.MOLECULAR AND BIOCHEMICAL PARASITOLOGY. VOL. 160. ISSUE 1. P. 1-7 40 61% 29
5 PEGG, AE , (2009) S-ADENOSYLMETHIONINE DECARBOXYLASE.ESSAYS IN BIOCHEMISTRY, VOL 46. VOL. 46. ISSUE . P. 25-45 27 71% 36
6 BALE, S , EALICK, SE , (2010) STRUCTURAL BIOLOGY OF S-ADENOSYLMETHIONINE DECARBOXYLASE.AMINO ACIDS. VOL. 38. ISSUE 2. P. 451 -460 28 64% 17
7 KHOMUTOV, MA , WEISELL, J , HYVONEN, M , KEINANEN, TA , VEPSALAINEN, J , ALHONEN, L , KHOMUTOV, AR , KOCHETKOV, SN , (2013) HYDROXYLAMINE DERIVATIVES FOR REGULATION OF SPERMINE AND SPERMIDINE METABOLISM.BIOCHEMISTRY-MOSCOW. VOL. 78. ISSUE 13. P. 1431-1446 33 51% 1
8 HEBY, O , ROBERTS, SC , ULLMAN, B , (2003) POLYAMINE BIOSYNTHETIC ENZYMES AS DRUG TARGETS IN PARASITIC PROTOZOA.BIOCHEMICAL SOCIETY TRANSACTIONS. VOL. 31. ISSUE . P. 415-419 23 82% 54
9 XIONG, HS , STANLEY, BA , PEGG, AE , (1999) ROLE OF CYSTEINE-82 IN THE CATALYTIC MECHANISM OF HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE.BIOCHEMISTRY. VOL. 38. ISSUE 8. P. 2462-2470 24 92% 23
10 PERSSON, L , (2007) ORNITHINE DECARBOXYLASE AND S-ADENOSYLMETHIONINE DECARBOXYLASE IN TRYPANOSOMATIDS.BIOCHEMICAL SOCIETY TRANSACTIONS. VOL. 35. ISSUE . P. 314-317 29 60% 7

Classes with closest relation at Level 1


Rank Class id link
1 100 POLYAMINES//ORNITHINE DECARBOXYLASE//ANTIZYME
2 16563 AMINE PHARMA//RIBOSOME MODULATION FACTOR//CALDOPENTAMINE
3 22214 MTAP//METHYLTHIOADENOSINE PHOSPHORYLASE//METHIONINE SALVAGE PATHWAY
4 14422 TRYPANOTHIONE REDUCTASE//TRYPANOTHIONE//TRYPAREDOXIN
5 6509 HUMAN AFRICAN TRYPANOSOMIASIS//TRYPANOSOMA BRUCEI GAMBIENSE//SLEEPING SICKNESS
6 18997 HYPUSINE//EIF5A//DEOXYHYPUSINE SYNTHASE
7 26603 AMBAZONE//ADENOSYLMETHIONINE DECARBOXYLASE INHIBITORS//DIAMINE OXIDASE INHIBITORS
8 23892 CHIRAL GLYCINE EQUIVALENT//1 CHLORO 1 N 15NITROSOCYCLOHEXANE//D HOMOSERINE
9 13361 GLYCOSOME//UNIDAD BIOQUIM PARASITOS//TROP DIS UNIT
10 1946 POLYAMINES//PUTRESCINE//SPERMIDINE

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