Class information for:
Level 1: IMEXON//CYANOAZIRIDINE//AZIRIDINE 2 CARBOXAMIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
33598 122 25.4 47%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
210 3       IMMUNOLOGY//JOURNAL OF INTERFERON RESEARCH//NK CELLS 51916
3041 2             PSK//OK 432//IMEXON 2463
33598 1                   IMEXON//CYANOAZIRIDINE//AZIRIDINE 2 CARBOXAMIDE 122

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IMEXON authKW 4486702 18% 81% 22
2 CYANOAZIRIDINE authKW 750875 2% 100% 3
3 AZIRIDINE 2 CARBOXAMIDE authKW 500583 2% 100% 2
4 LEAKADINE authKW 333721 2% 67% 2
5 2 CYANAZIRIDINES authKW 250292 1% 100% 1
6 AMP423 authKW 250292 1% 100% 1
7 ARSENIC TRIOXIDE 1 4 BENZODIAZEPINE authKW 250292 1% 100% 1
8 AZIMEXONE authKW 250292 1% 100% 1
9 DIARYL OXAZOLE authKW 250292 1% 100% 1
10 HUMAN LARGE CELL LYMPHOMA authKW 250292 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 600 37% 0% 45
2 Pharmacology & Pharmacy 268 29% 0% 35
3 Immunology 253 23% 0% 28
4 Chemistry, Medicinal 35 6% 0% 7
5 Medicine, Research & Experimental 26 7% 0% 8
6 Pathology 18 4% 0% 5
7 Biology 18 4% 0% 5
8 Hematology 14 4% 0% 5
9 Allergy 12 2% 0% 2
10 Respiratory System 6 2% 0% 3

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MF VLADIMINSKY MOSCOW REG SCI 250292 1% 100% 1
2 US ONCOL PHASE GRP 1 250292 1% 100% 1
3 BASIC PATHOL B3 125145 1% 50% 1
4 INVEST CANC THER EUT PHASE PROGRAM 1 125145 1% 50% 1
5 PHYSICOCHIM THEOR CHIM INFORMAT 66741 2% 13% 2
6 CANC CAROLINAS 62571 1% 25% 1
7 JOHNSON CANC 35754 1% 14% 1
8 PIROL B2 25025 2% 5% 2
9 ARIZONA CANC 18615 9% 1% 11
10 WILHELMINENSPITAL 11917 1% 5% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF IMMUNOPHARMACOLOGY 79285 7% 4% 8
2 EXPERIMENTAL PATHOLOGY 8469 4% 1% 5
3 JOURNAL OF BIOLOGICAL RESPONSE MODIFIERS 8215 3% 1% 4
4 INMUNOLOGIA 7047 2% 1% 2
5 RECENT RESULTS IN CANCER RESEARCH 4293 2% 1% 3
6 INVESTIGATIONAL NEW DRUGS 1564 3% 0% 4
7 TUMORDIAGNOSTIK & THERAPIE 1285 2% 0% 2
8 CANCER IMMUNOLOGY IMMUNOTHERAPY 917 3% 0% 4
9 ANTI-CANCER DRUGS 686 2% 0% 3
10 IRCS MEDICAL SCIENCE-BIOCHEMISTRY 685 2% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 IMEXON 4486702 18% 81% 22 Search IMEXON Search IMEXON
2 CYANOAZIRIDINE 750875 2% 100% 3 Search CYANOAZIRIDINE Search CYANOAZIRIDINE
3 AZIRIDINE 2 CARBOXAMIDE 500583 2% 100% 2 Search AZIRIDINE+2+CARBOXAMIDE Search AZIRIDINE+2+CARBOXAMIDE
4 LEAKADINE 333721 2% 67% 2 Search LEAKADINE Search LEAKADINE
5 2 CYANAZIRIDINES 250292 1% 100% 1 Search 2+CYANAZIRIDINES Search 2+CYANAZIRIDINES
6 AMP423 250292 1% 100% 1 Search AMP423 Search AMP423
7 ARSENIC TRIOXIDE 1 4 BENZODIAZEPINE 250292 1% 100% 1 Search ARSENIC+TRIOXIDE+1+4+BENZODIAZEPINE Search ARSENIC+TRIOXIDE+1+4+BENZODIAZEPINE
8 AZIMEXONE 250292 1% 100% 1 Search AZIMEXONE Search AZIMEXONE
9 DIARYL OXAZOLE 250292 1% 100% 1 Search DIARYL+OXAZOLE Search DIARYL+OXAZOLE
10 HUMAN LARGE CELL LYMPHOMA 250292 1% 100% 1 Search HUMAN+LARGE+CELL+LYMPHOMA Search HUMAN+LARGE+CELL+LYMPHOMA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 REMERS, WA , DORR, RT , (2012) CHEMISTRY AND PHARMACOLOGY OF IMEXON AND RELATED CYANOAZIRIDINES.CURRENT MEDICINAL CHEMISTRY. VOL. 19. ISSUE 33. P. 5745 -5753 19 90% 2
2 CHO, H , KOTO, M , RIESTERER, O , MOLKENTINE, DP , GIRI, U , MILAS, L , STORY, MD , HA, CS , RAJU, U , (2009) IMEXON AUGMENTS SENSITIVITY OF HUMAN LYMPHOMA CELLS TO IONIZING RADIATION: IN VITRO EXPERIMENTAL STUDY.ANTICANCER RESEARCH. VOL. 29. ISSUE 11. P. 4409-4415 18 60% 2
3 DORR, RT , WISNER, L , SAMULITIS, BK , LANDOWSKI, TH , REMERS, WA , (2012) ANTI-TUMOR ACTIVITY AND MECHANISM OF ACTION FOR A CYANOAZIRIDINE-DERIVATIVE, AMP423.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 69. ISSUE 4. P. 1039-1049 16 62% 2
4 KURZROCK, R , BOYTIM, M , HERSH, E , DORR, R , LA PAGLIA, A , TSE, S , NAING, A , WHELER, J , HONG, D , NG, C , ET AL (2010) A PHASE I TRIAL OF IMEXON, A PRO-OXIDANT, IN COMBINATION WITH DOCETAXEL FOR THE TREATMENT OF PATIENTS WITH ADVANCED BREAST, NON-SMALL CELL LUNG AND PROSTATE CANCER.INVESTIGATIONAL NEW DRUGS. VOL. 28. ISSUE 5. P. 634 -640 10 83% 9
5 BARR, PM , MILLER, TP , FRIEDBERG, JW , PETERSON, DR , BARAN, AM , HERR, M , SPIER, CM , CUI, HY , ROE, DJ , PERSKY, DO , ET AL (2014) PHASE 2 STUDY OF IMEXON, A PROOXIDANT MOLECULE, IN RELAPSED AND REFRACTORY B-CELL NON-HODGKIN LYMPHOMA.BLOOD. VOL. 124. ISSUE 8. P. 1259 -1265 14 48% 6
6 LANDOWSKI, TH , GUNTLE, GP , ZHAO, DZ , JAGADISH, B , MASH, EA , DORR, RT , RAGHUNAND, N , (2016) MAGNETIC RESONANCE IMAGING IDENTIFIES DIFFERENTIAL RESPONSE TO PRO-OXIDANT CHEMOTHERAPY IN A XENOGRAFT MODEL.TRANSLATIONAL ONCOLOGY. VOL. 9. ISSUE 3. P. 228 -235 12 48% 0
7 DRAGOVICH, T , GORDON, M , MENDELSON, D , WONG, L , MODIANO, M , CHOW, HHS , SAMULITIS, B , O'DAY, S , GRENIER, K , HERSH, E , ET AL (2007) PHASE I TRIAL OF IMEXON IN PATIENTS WITH ADVANCED MALIGNANCY.JOURNAL OF CLINICAL ONCOLOGY. VOL. 25. ISSUE 13. P. 1779-1784 11 52% 29
8 KHEFFACHE, D , GUEMMOUR, H , OUAMERALI, O , (2012) PROTOTROPIC TAUTOMERISM AND MICROSOLVATION IN ANTITUMOR DRUG IMEXON: A DFT STUDY.STRUCTURAL CHEMISTRY. VOL. 23. ISSUE 5. P. 1547-1557 8 50% 2
9 SHEVELEVA, EV , LANDOWSKI, TH , SAMULITIS, BK , BARTHOLOMEUSZ, G , POWIS, G , DORR, RT , (2012) IMEXON INDUCES AN OXIDATIVE ENDOPLASMIC RETICULUM STRESS RESPONSE IN PANCREATIC CANCER CELLS.MOLECULAR CANCER RESEARCH. VOL. 10. ISSUE 3. P. 392 -400 10 37% 3
10 KUEHL, PJ , HOYE, WL , MYRDAL, PB , (2006) PREFORMULATION STUDIES ON IMEXON.DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. VOL. 32. ISSUE 6. P. 687-697 7 58% 9

Classes with closest relation at Level 1


Rank Class id link
1 35140 ANTI COMPLEMENTARY POLYSACCHARIDE ARABINOGALACTAN//CYTOPOIESIS//MED ANAT 251 SHIKATACHO
2 32252 3 AMINO 4 5 DICARBOALKOXY DELTA 3 PYRROLIDON 2 YL 5 ACETIC ACID ESTERS//ACETAL RING CLOSURE//ALDOL RING CLOSURE
3 23898 POLY ICLC//RAUSCHER MURINE LEUKEMIA VIRUS//BANZI VIRUS
4 25399 CARBETIMER//POLYERGA//SPLEEN PEPTIDES
5 35237 2 NBDG//2 NBDLG//FLUORESCENT GLUCOSE
6 36462 ZBP 89//ZNF148//BAK GENES
7 11429 CANCER IMMUNOLOGY IMMUNOTHERAPY//ANTITUMOR CYTOTOXIC LYMPHOCYTES//THYMIC IMMUNE REACTIVITY
8 27359 BUCILLAMINE//ACTARIT//LOBENZARIT
9 27014 LIVER LECTINS//GLUTARON//HYG GOLDENFELSSTR 1921
10 26135 LYMPHATIC TARGETING//ACTIVATED CARBON PARTICLES//BIOMED ENGN CANC

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