Class information for:
Level 1: TYROSINE PHENOL LYASE//TRYPTOPHAN SYNTHASE//TRYPTOPHANASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15558 705 33.0 51%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
278 3       CORYNEBACTERIUM GLUTAMICUM//ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//BIOCHEMISTRY & MOLECULAR BIOLOGY 43163
1584 2             D AMINO ACID OXIDASE//D SERINE//SERINE RACEMASE 7221
15558 1                   TYROSINE PHENOL LYASE//TRYPTOPHAN SYNTHASE//TRYPTOPHANASE 705

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TYROSINE PHENOL LYASE authKW 845911 4% 78% 25
2 TRYPTOPHAN SYNTHASE authKW 726762 5% 48% 35
3 TRYPTOPHANASE authKW 644492 4% 60% 25
4 TRYPTOPHAN INDOLE LYASE authKW 346490 1% 100% 8
5 SYMBIOBACTERIUM THERMOPHILUM authKW 259867 1% 100% 6
6 ALPHA PROTON EXCHANGE authKW 222742 1% 86% 6
7 SYMBIOBACTERIUM TOEBII authKW 222742 1% 86% 6
8 SYMBIOBACTERIUM authKW 216556 1% 100% 5
9 SECT ENZYME STRUCT FUNCT address 180462 1% 83% 5
10 BIOCHEM PHARMACOL BLDG 8 RM 2A09 address 173245 1% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 5212 69% 0% 489
2 Biophysics 821 13% 0% 93
3 Biotechnology & Applied Microbiology 354 11% 0% 76
4 Microbiology 124 7% 0% 49
5 Biochemical Research Methods 63 4% 0% 29
6 Chemistry, Organic 55 6% 0% 40
7 Mathematical & Computational Biology 40 2% 0% 12
8 Chemistry, Medicinal 25 3% 0% 18
9 Biology 17 2% 0% 15
10 Crystallography 5 1% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT ENZYME STRUCT FUNCT 180462 1% 83% 5
2 BIOCHEM PHARMACOL BLDG 8 RM 2A09 173245 1% 100% 4
3 BIOCHEM 015 86622 0% 100% 2
4 ENZYME STRUCT FUNCT SECT 86622 0% 100% 2
5 MICROBIAL CONVERS RU 86622 0% 100% 2
6 NIH BIOCHEM PHARMACOL 86622 0% 100% 2
7 METALLOENZYME STUDIES 65598 3% 7% 21
8 UNITE BIOCHIM CELLULAIRE CNRS URA 1129 57747 0% 67% 2
9 BACTERIOL HYBRIDOMA TECHNOL 43311 0% 100% 1
10 BIOACT MOLECULES 43311 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMISTRY 11306 17% 0% 118
2 PROTEINS-STRUCTURE FUNCTION AND GENETICS 3500 1% 1% 6
3 JOURNAL OF BIOLOGICAL CHEMISTRY 1982 12% 0% 85
4 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS 1967 2% 0% 12
5 EUROPEAN JOURNAL OF BIOCHEMISTRY 1934 4% 0% 30
6 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY 1319 0% 2% 2
7 MOLECULAR BIOLOGY 1099 2% 0% 11
8 BIOORGANICHESKAYA KHIMIYA 837 1% 0% 8
9 JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 789 1% 0% 9
10 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 712 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TYROSINE PHENOL LYASE 845911 4% 78% 25 Search TYROSINE+PHENOL+LYASE Search TYROSINE+PHENOL+LYASE
2 TRYPTOPHAN SYNTHASE 726762 5% 48% 35 Search TRYPTOPHAN+SYNTHASE Search TRYPTOPHAN+SYNTHASE
3 TRYPTOPHANASE 644492 4% 60% 25 Search TRYPTOPHANASE Search TRYPTOPHANASE
4 TRYPTOPHAN INDOLE LYASE 346490 1% 100% 8 Search TRYPTOPHAN+INDOLE+LYASE Search TRYPTOPHAN+INDOLE+LYASE
5 SYMBIOBACTERIUM THERMOPHILUM 259867 1% 100% 6 Search SYMBIOBACTERIUM+THERMOPHILUM Search SYMBIOBACTERIUM+THERMOPHILUM
6 ALPHA PROTON EXCHANGE 222742 1% 86% 6 Search ALPHA+PROTON+EXCHANGE Search ALPHA+PROTON+EXCHANGE
7 SYMBIOBACTERIUM TOEBII 222742 1% 86% 6 Search SYMBIOBACTERIUM+TOEBII Search SYMBIOBACTERIUM+TOEBII
8 SYMBIOBACTERIUM 216556 1% 100% 5 Search SYMBIOBACTERIUM Search SYMBIOBACTERIUM
9 TRYPTOPHAN SYNTHASE ALPHA SUBUNIT 155916 1% 60% 6 Search TRYPTOPHAN+SYNTHASE+ALPHA+SUBUNIT Search TRYPTOPHAN+SYNTHASE+ALPHA+SUBUNIT
10 MICROBIAL COMMENSALISM 129934 0% 100% 3 Search MICROBIAL+COMMENSALISM Search MICROBIAL+COMMENSALISM

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 RABONI, S , BETTATI, S , MOZZARELLI, A , (2009) TRYPTOPHAN SYNTHASE: A MINE FOR ENZYMOLOGISTS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 66. ISSUE 14. P. 2391 -2403 73 88% 20
2 DUNN, MF , (2012) ALLOSTERIC REGULATION OF SUBSTRATE CHANNELING AND CATALYSIS IN THE TRYPTOPHAN SYNTHASE BIENZYME COMPLEX.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 519. ISSUE 2. P. 154-166 57 97% 27
3 MILES, EW , (2001) TRYPTOPHAN SYNTHASE: A MULTIENZYME COMPLEX WITH AN INTRAMOLECULAR TUNNEL.CHEMICAL RECORD. VOL. 1. ISSUE 2. P. 140 -151 56 98% 43
4 NGO, H , KIMMICH, N , HARRIS, R , NIKS, D , BLUMENSTEIN, L , KULIK, V , BARENDS, TR , SCHLICHTING, I , DUNN, MF , (2007) ALLOSTERIC REGULATION OF SUBSTRATE CHANNELING IN TRYPTOPHAN SYNTHASE: MODULATION OF THE L-SERINE REACTION IN STAGE I OF THE SS-REACTION BY ALPHA-SITE LIGANDS.BIOCHEMISTRY. VOL. 46. ISSUE 26. P. 7740 -7753 49 92% 18
5 AXE, JM , BOEHR, DD , (2013) LONG-RANGE INTERACTIONS IN THE ALPHA SUBUNIT OF TRYPTOPHAN SYNTHASE HELP TO COORDINATE LIGAND BINDING, CATALYSIS, AND SUBSTRATE CHANNELING.JOURNAL OF MOLECULAR BIOLOGY. VOL. 425. ISSUE 9. P. 1527-1545 52 67% 11
6 DUNN, MF , NIKS, D , NGO, H , BARENDS, TRM , SCHLICHTING, I , (2008) TRYPTOPHAN SYNTHASE: THE WORKINGS OF A CHANNELING NANOMACHINE.TRENDS IN BIOCHEMICAL SCIENCES. VOL. 33. ISSUE 6. P. 254 -264 40 89% 46
7 MILES, EW , (1991) STRUCTURAL BASIS FOR CATALYSIS BY TRYPTOPHAN SYNTHASE.ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY. VOL. 64. ISSUE . P. 93 -+ 83 86% 1
8 NIKS, D , HILARIO, E , DIERKERS, A , NGO, H , BORCHARDT, D , NEUBAUER, TJ , FAN, L , MUELLER, LJ , DUNN, MF , (2013) ALLOSTERY AND SUBSTRATE CHANNELING IN THE TRYPTOPHAN SYNTHASE BIENZYME COMPLEX: EVIDENCE FOR TWO SUBUNIT CONFORMATIONS AND FOUR QUATERNARY STATES.BIOCHEMISTRY. VOL. 52. ISSUE 37. P. 6396-6411 45 74% 5
9 WEYAND, M , SCHLICHTING, I , DUNN, MF , NGO, H , HARRIS, R , KIMMICH, N , CASINO, P , NIKS, D , BLUMENSTEIN, L , BARENDS, TR , ET AL (2007) SYNTHESIS AND CHARACTERIZATION OF ALLOSTERIC PROBES OF SUBSTRATE CHANNELING IN THE TRYPTOPHAN SYNTHASE BIENZYME COMPLEX.BIOCHEMISTRY. VOL. 46. ISSUE 26. P. 7713 -7727 42 88% 18
10 DIERKERS, AT , NIKS, D , SCHLICHTING, I , DUNN, MF , (2009) TRYPTOPHAN SYNTHASE: STRUCTURE AND FUNCTION OF THE MONOVALENT CATION SITE.BIOCHEMISTRY. VOL. 48. ISSUE 46. P. 10997 -11010 35 100% 9

Classes with closest relation at Level 1


Rank Class id link
1 12247 ASPARTATE AMINOTRANSFERASE//PYRIDOXAL 5 PHOSPHATE//AMINOTRANSFERASE
2 22226 THREONINE DEHYDROGENASE//L THREONINE DEHYDROGENASE//TDC OPERON
3 23892 CHIRAL GLYCINE EQUIVALENT//1 CHLORO 1 N 15NITROSOCYCLOHEXANE//D HOMOSERINE
4 22175 HISTIDINE BIOSYNTHESIS//BETA ALPHA8 BARREL//INDOLE 3 GLYCEROL PHOSPHATE SYNTHASE
5 9861 ANTHRANILATE SYNTHASE//CHORISMATE MUTASE//CHORISMATE
6 21291 5 DEOXYPYRIDOXAL//PYRIDOXAL//METALLATION OF BIOLOGICAL LIGANDS
7 21832 HOMOCYSTINURIA//CYSTATHIONINE BETA SYNTHASE//CYSTATHIONINE BETA SYNTHASE DEFICIENCY
8 15175 STAPHYLOCOCCAL NUCLEASE//THERMODYNAMIC MOLECULAR SWITCH//T4 LYSOZYME
9 16095 BPTI//BAKER CHEM CHEM BIOL//BOVINE PANCREATIC TRYPSIN INHIBITOR
10 22761 METHIONINE DEPENDENCE//METHIONINASE//METHIONINE GAMMA LYASE

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