Class information for:
Level 1: CALPAIN//CALPASTATIN//CALPAIN INHIBITOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1530 2610 42.2 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
180 3       DUCHENNE MUSCULAR DYSTROPHY//DYSTROPHIN//MUSCULAR DYSTROPHY 56784
2896 2             CALPAIN//CALPASTATIN//CALPAIN INHIBITOR 2802
1530 1                   CALPAIN//CALPASTATIN//CALPAIN INHIBITOR 2610

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CALPAIN authKW 3788194 34% 37% 881
2 CALPASTATIN authKW 1497930 9% 54% 239
3 CALPAIN INHIBITOR authKW 561548 3% 68% 71
4 M CALPAIN authKW 313428 2% 62% 43
5 CALPAIN PROJECT address 204162 1% 73% 24
6 ADV SCI BIOMOL address 125322 1% 71% 15
7 P94 authKW 117948 0% 92% 11
8 SENJU OCULAR SCI address 108258 1% 49% 19
9 LP82 authKW 94748 0% 90% 9
10 CALPAIN II authKW 89977 0% 77% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 9111 49% 0% 1289
2 Biophysics 3292 14% 0% 357
3 Neurosciences 2546 20% 0% 523
4 Cell Biology 2101 16% 0% 420
5 Ophthalmology 237 3% 0% 84
6 Chemistry, Medicinal 160 3% 0% 81
7 Physiology 89 3% 0% 80
8 Peripheral Vascular Diseases 88 2% 0% 65
9 Hematology 58 2% 0% 60
10 Medicine, Research & Experimental 42 3% 0% 72

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CALPAIN PROJECT 204162 1% 73% 24
2 ADV SCI BIOMOL 125322 1% 71% 15
3 SENJU OCULAR SCI 108258 1% 49% 19
4 ORAL MOL BIOL OPHTHALMOL 83181 0% 89% 8
5 BIOL FUNCTBUNKYO KU 63684 0% 78% 7
6 PROTEOLYT NEUROSCI 62991 1% 18% 30
7 MOL CELLULAR REGULATCHIKUSA KU 52102 0% 64% 7
8 DENT OPHTHALMOL 46790 0% 100% 4
9 ENZYMAT REGULAT CELL FUNCT 38205 0% 47% 7
10 ISTAB USC 35093 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOCHEMISTRY 3964 2% 1% 61
2 JOURNAL OF NEUROSCIENCE RESEARCH 2399 2% 0% 43
3 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2366 5% 0% 121
4 JOURNAL OF BIOLOGICAL CHEMISTRY 2282 7% 0% 181
5 BIOLOGICAL CHEMISTRY 2243 1% 1% 25
6 JOURNAL OF NEUROCHEMISTRY 1993 2% 0% 61
7 NEUROCHEMICAL RESEARCH 1694 1% 0% 33
8 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1639 2% 0% 50
9 FEBS LETTERS 1300 3% 0% 70
10 BIOCHEMICAL JOURNAL 1166 2% 0% 56

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CALPAIN 3788194 34% 37% 881 Search CALPAIN Search CALPAIN
2 CALPASTATIN 1497930 9% 54% 239 Search CALPASTATIN Search CALPASTATIN
3 CALPAIN INHIBITOR 561548 3% 68% 71 Search CALPAIN+INHIBITOR Search CALPAIN+INHIBITOR
4 M CALPAIN 313428 2% 62% 43 Search M+CALPAIN Search M+CALPAIN
5 P94 117948 0% 92% 11 Search P94 Search P94
6 LP82 94748 0% 90% 9 Search LP82 Search LP82
7 CALPAIN II 89977 0% 77% 10 Search CALPAIN+II Search CALPAIN+II
8 CALPAIN INHIBITION 89977 0% 77% 10 Search CALPAIN+INHIBITION Search CALPAIN+INHIBITION
9 MU CALPAIN 85976 1% 29% 25 Search MU+CALPAIN Search MU+CALPAIN
10 CALPAIN 2 79063 0% 52% 13 Search CALPAIN+2 Search CALPAIN+2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GOLL, DE , THOMPSON, VF , LI, HQ , WEI, W , CONG, JY , (2003) THE CALPAIN SYSTEM.PHYSIOLOGICAL REVIEWS. VOL. 83. ISSUE 3. P. 731 -801 345 77% 1533
2 PIETSCH, M , CHUA, KCH , ABELL, AD , (2010) CALPAINS: ATTRACTIVE TARGETS FOR THE DEVELOPMENT OF SYNTHETIC INHIBITORS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 3. P. 270-293 219 78% 37
3 STORR, SJ , CARRAGHER, NO , FRAME, MC , PARR, T , MARTIN, SG , (2011) THE CALPAIN SYSTEM AND CANCER.NATURE REVIEWS CANCER. VOL. 11. ISSUE 5. P. 364 -374 136 71% 130
4 CROALL, DE , DEMARTINO, GN , (1991) CALCIUM-ACTIVATED NEUTRAL PROTEASE (CALPAIN) SYSTEM - STRUCTURE, FUNCTION, AND REGULATION.PHYSIOLOGICAL REVIEWS. VOL. 71. ISSUE 3. P. 813-847 213 61% 739
5 CARRAGHER, NO , (2006) CALPAIN INHIBITION: A THERAPEUTIC STRATEGY TARGETING MULTIPLE DISEASE STATES.CURRENT PHARMACEUTICAL DESIGN. VOL. 12. ISSUE 5. P. 615-638 165 74% 101
6 CAMPBELL, RL , DAVIES, PL , (2012) STRUCTURE-FUNCTION RELATIONSHIPS IN CALPAINS.BIOCHEMICAL JOURNAL. VOL. 447. ISSUE . P. 335 -351 95 87% 60
7 FRANCO, SJ , HUTTENLOCHER, A , (2005) REGULATING CELL MIGRATION: CALPAINS MAKE THE CUT.JOURNAL OF CELL SCIENCE. VOL. 118. ISSUE 17. P. 3829-3838 109 79% 268
8 DONKOR, IO , (2011) CALPAIN INHIBITORS: A SURVEY OF COMPOUNDS REPORTED IN THE PATENT AND SCIENTIFIC LITERATURE.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 21. ISSUE 5. P. 601 -636 97 84% 33
9 ONO, Y , SAIDO, TC , SORIMACHI, H , (2016) CALPAIN RESEARCH FOR DRUG DISCOVERY: CHALLENGES AND POTENTIAL.NATURE REVIEWS DRUG DISCOVERY. VOL. 15. ISSUE 12. P. 854 -876 147 53% 0
10 ONO, Y , OJIMA, K , SHINKAI-OUCHI, F , HATA, S , SORIMACHI, H , (2016) AN ECCENTRIC CALPAIN, CAPN3/P94/CALPAIN-3.BIOCHIMIE. VOL. 122. ISSUE . P. 169 -187 131 55% 1

Classes with closest relation at Level 1


Rank Class id link
1 20404 CALPAIN 10//MED CELLULAR MOL PHYSIOL BIOSTAT//MOL GENET COMPLEX MONOGEN DISORDERS
2 8640 DYSFERLIN//LIMB GIRDLE MUSCULAR DYSTROPHY//SARCOGLYCAN
3 35227 DYSTROPHIN DYS//GENE TRANSFECTION IN VIVO//INTERNAL MED ORGANOL PATHOL CARDIOVASC
4 35753 NA DEPENDENT CA2 UPTAKE//TISSUE INHIBITOR OF METALLOPROTEASE 2//GIALPHA
5 3294 TENDERNESS//MEAT SCIENCE//TENDERIZATION
6 25040 APOPTOSIS INDUCING FACTOR//AIF//AMID
7 32412 1 2 OLEOYLACETYLGLYCEROL OAG//BETA IPKC//BIBLICAL TRAGEDY
8 18351 LYSOSOME//OSMOTIC SENSITIVITY//CALPAIN CATHEPSIN HYPOTHESIS
9 29194 PLATELET APOPTOSIS//COATED PLATELET//STUDY HUMAN OPERATOR PERFORMANCE
10 27611 CARBAMOYLSILANE//ALPHA KETOAMIDES//N ACETYLISATIN

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