Class information for:
Level 1: C FLIP//FADD//DEATH EFFECTOR DOMAIN

Basic class information

Class id #P Avg. number of
references
Database coverage
of references
14699 755 47.5 95%



Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.



Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
441 3       TRAIL//SURVIVIN//APOPTOSIS 26474
306 2             TRAIL//SURVIVIN//APOPTOSIS 18497
14699 1                   C FLIP//FADD//DEATH EFFECTOR DOMAIN 755

Terms with highest relevance score



rank Term termType Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 C FLIP authKW 1201152 11% 35% 86
2 FADD authKW 506343 6% 26% 48
3 DEATH EFFECTOR DOMAIN authKW 223978 2% 46% 12
4 FLIP authKW 194224 5% 14% 35
5 FADD PHOSPHORYLATION authKW 161771 1% 100% 4
6 CELLULAR FLICE LIKE INHIBITORY PROTEIN authKW 129415 1% 80% 4
7 TUMORIMMUNOL PROGRAM address 129399 2% 27% 12
8 CASPASE 8 authKW 117465 6% 6% 46
9 C FLIPL authKW 94357 1% 33% 7
10 FLICE INHIBITORY PROTEIN authKW 92437 1% 57% 4

Web of Science journal categories



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 Cell Biology 3150 34% 0% 254
2 Biochemistry & Molecular Biology 1470 38% 0% 289
3 Immunology 713 16% 0% 122
4 Oncology 567 16% 0% 120
5 Mathematical & Computational Biology 222 3% 0% 26
6 Medicine, Research & Experimental 80 5% 0% 38
7 Pathology 58 3% 0% 24
8 Hematology 30 3% 0% 21
9 Biology 30 3% 0% 19
10 Biophysics 27 3% 0% 25

Address terms



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 TUMORIMMUNOL PROGRAM 129399 2% 27% 12
2 IUNICS IDISPA 90989 1% 38% 6
3 CHANGZHOU HIGH TECH 87368 1% 20% 11
4 UNIV ROMAND MED LEGALE SITE GENEVE 64704 1% 40% 4
5 NEUROBIOL DRUG ABUSE GRP 60661 0% 50% 3
6 DRUG ISTANCE 53918 1% 33% 4
7 BIL BIOMED 44613 1% 14% 8
8 ANIM NAT OURCES BOVINE FUNCT GENOM 40443 0% 100% 1
9 ARTMENT VET MED 40443 0% 100% 1
10 BIOL S III 40443 0% 100% 1

Journals



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 CELL DEATH AND DIFFERENTIATION 13059 4% 1% 32
2 PROGRAMMED CELL DEATH 3675 0% 9% 1
3 CELL DEATH & DISEASE 3341 2% 1% 14
4 PEZCOLLER FOUNDATION SYMPOSIA 2866 2% 1% 12
5 JOURNAL OF IMMUNOLOGY 1342 6% 0% 43
6 JOURNAL OF BIOLOGICAL CHEMISTRY 1152 9% 0% 68
7 MOLECULAR CELL 879 1% 0% 11
8 MOLECULAR SYSTEMS BIOLOGY 848 1% 1% 4
9 ONCOGENE 697 2% 0% 18
10 EUROPEAN JOURNAL OF IMMUNOLOGY 669 2% 0% 15

Author Key Words



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
LCSH search Wikipedia search
1 C FLIP 1201152 11% 35% 86 Search C+FLIP Search C+FLIP
2 FADD 506343 6% 26% 48 Search FADD Search FADD
3 DEATH EFFECTOR DOMAIN 223978 2% 46% 12 Search DEATH+EFFECTOR+DOMAIN Search DEATH+EFFECTOR+DOMAIN
4 FLIP 194224 5% 14% 35 Search FLIP Search FLIP
5 FADD PHOSPHORYLATION 161771 1% 100% 4 Search FADD+PHOSPHORYLATION Search FADD+PHOSPHORYLATION
6 CELLULAR FLICE LIKE INHIBITORY PROTEIN 129415 1% 80% 4 Search CELLULAR+FLICE+LIKE+INHIBITORY+PROTEIN Search CELLULAR+FLICE+LIKE+INHIBITORY+PROTEIN
7 CASPASE 8 117465 6% 6% 46 Search CASPASE+8 Search CASPASE+8
8 C FLIPL 94357 1% 33% 7 Search C+FLIPL Search C+FLIPL
9 FLICE INHIBITORY PROTEIN 92437 1% 57% 4 Search FLICE+INHIBITORY+PROTEIN Search FLICE+INHIBITORY+PROTEIN
10 EXTRINSIC APOPTOTIC SIGNALING PATHWAY 80886 0% 100% 2 Search EXTRINSIC+APOPTOTIC+SIGNALING+PATHWAY Search EXTRINSIC+APOPTOTIC+SIGNALING+PATHWAY

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.



Rank Reference # ref. in
cl.
Shr. of ref. in
cl.
Citations
1 TSUCHIYA, Y , NAKABAYASHI, O , NAKANO, H , (2015) FLIP THE SWITCH: REGULATION OF APOPTOSIS AND NECROPTOSIS BY CFLIP.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 16. ISSUE 12. P. 30321 -30341 84 68% 6
2 BUDD, RC , YEH, WC , TSCHOPP, J , (2006) CFLIP REGULATION OF LYMPHOCYTE ACTIVATION AND DEVELOPMENT.NATURE REVIEWS IMMUNOLOGY. VOL. 6. ISSUE 3. P. 196-204 66 57% 174
3 KATAOKA, T , (2005) THE CASPASE-8 MODULATOR C-FLIP.CRITICAL REVIEWS IN IMMUNOLOGY. VOL. 25. ISSUE 1. P. 31-58 102 41% 122
4 LAVRIK, IN , (2014) SYSTEMS BIOLOGY OF DEATH RECEPTOR NETWORKS: LIVE AND LET DIE.CELL DEATH & DISEASE. VOL. 5. ISSUE . P. - 41 67% 17
5 OZTURK, S , SCHLEICH, K , LAVRIK, IN , (2012) CELLULAR FLICE-LIKE INHIBITORY PROTEINS (C-FLIPS): FINE-TUNERS OF LIFE AND DEATH DECISIONS.EXPERIMENTAL CELL RESEARCH. VOL. 318. ISSUE 11. P. 1324-1331 39 71% 39
6 VALMIKI, MG , RAMOS, JW , (2009) DEATH EFFECTOR DOMAIN-CONTAINING PROTEINS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 66. ISSUE 5. P. 814 -830 65 42% 62
7 YU, JW , SHI, Y , (2008) FLIP AND THE DEATH EFFECTOR DOMAIN FAMILY.ONCOGENE. VOL. 27. ISSUE 48. P. 6216-6227 53 50% 80
8 WERNER, MH , WU, CW , WALSH, CM , (2006) EMERGING ROLES FOR THE DEATH ADAPTOR FADD IN DEATH RECEPTOR AVIDITY AND CELL CYCLE REGULATION.CELL CYCLE. VOL. 5. ISSUE 20. P. 2332 -2338 49 60% 21
9 SHIRLEY, S , MICHEAU, O , (2013) TARGETING C-FLIP IN CANCER.CANCER LETTERS. VOL. 332. ISSUE 2. P. 141-150 47 41% 44
10 YANG, JK , (2008) FLIP AS AN ANTI-CANCER THERAPEUTIC TARGET.YONSEI MEDICAL JOURNAL. VOL. 49. ISSUE 1. P. 19 -27 44 57% 32

Classes with closest relation at Level 1



Rank Class id link
1 31962 PEA 15//IST ENDOCRINOL ONCOL SPERIMENTALE GAETANO SALVA//BIKDD
2 10004 NECROPTOSIS//RIP3//RIP1
3 1157 TRAIL//DR5//TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND
4 1319 FAS//FAS LIGAND//FASL
5 1845 APAF 1//CASPASE 2//CASPASE
6 28260 CASP8 652 6N DEL//CASPASE8//CASP8
7 23365 AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME//ALPS UNIT//DN T CELLS
8 26875 APO 1 ANTIBODY//APO I FAS APOPTOSIS//APOPTOSIS CYTOKINES
9 6794 XIAP//LIVIN//SMAC
10 33279 TIPE2//TNFAIP8//TNFAIP8L2 TIPE2

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