Class information for:
Level 1: FGF21//FIBROBLAST GROWTH FACTOR 21//FGF 21

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14626 759 43.1 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
1927 2             FGF21//FIBROBLAST GROWTH FACTOR//FIBROBLAST GROWTH FACTOR 21 5824
14626 1                   FGF21//FIBROBLAST GROWTH FACTOR 21//FGF 21 759

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FGF21 authKW 3711124 16% 75% 123
2 FIBROBLAST GROWTH FACTOR 21 authKW 2785088 12% 77% 90
3 FGF 21 authKW 877258 3% 84% 26
4 BETA KLOTHO authKW 595985 3% 74% 20
5 FGF19 authKW 528105 4% 41% 32
6 FIBROBLAST GROWTH FACTOR 21 FGF21 authKW 234059 1% 73% 8
7 IBT PROTE NANOTECHNOL address 128733 1% 80% 4
8 FIBROBLAST GROWTH FACTOR 19 authKW 121894 1% 30% 10
9 KLB authKW 90515 0% 75% 3
10 FGF21 RESISTANCE authKW 80459 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 11386 47% 0% 357
2 Cell Biology 1026 20% 0% 153
3 Biochemistry & Molecular Biology 503 25% 0% 187
4 Nutrition & Dietetics 187 5% 0% 36
5 Medicine, Research & Experimental 139 6% 0% 47
6 Physiology 117 5% 0% 40
7 Gastroenterology & Hepatology 82 4% 0% 30
8 Biophysics 71 5% 0% 35
9 Pharmacology & Pharmacy 13 5% 0% 40
10 Medical Laboratory Technology 12 1% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IBT PROTE NANOTECHNOL 128733 1% 80% 4
2 MOL EVOLUT TEAM 80459 0% 100% 2
3 CHINESE AMER DIABET COMPLICAT 55297 1% 13% 11
4 AGR BIOL FUNCT GENE 55215 1% 15% 9
5 ABORAT INNOVAT BIOMED 40230 0% 100% 1
6 ABORAT TRANSLAT BIOMED 40230 0% 100% 1
7 AFFILIATED PEOPLES HOSP 6 ENDOCRINOL METBOL 40230 0% 100% 1
8 AFFILIATED PEOPLES HOSP 6SHANGHAI DIABET SH 40230 0% 100% 1
9 AMER DIABET COMPLICAT 40230 0% 100% 1
10 BIOCHEMIDIPAZ 40230 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR METABOLISM 23652 2% 4% 14
2 CELL METABOLISM 15901 3% 2% 24
3 FRONTIERS IN ENDOCRINOLOGY 6893 1% 2% 10
4 ENDOCRINOLOGY 1621 4% 0% 32
5 DIABETES 1182 3% 0% 19
6 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 1110 3% 0% 26
7 CLINICAL ENDOCRINOLOGY 1031 2% 0% 14
8 CELL REPORTS 775 1% 0% 8
9 PHYSIOLOGICAL RESEARCH 721 1% 0% 7
10 VITAMINS AND HORMONES 658 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FGF21 3711124 16% 75% 123 Search FGF21 Search FGF21
2 FIBROBLAST GROWTH FACTOR 21 2785088 12% 77% 90 Search FIBROBLAST+GROWTH+FACTOR+21 Search FIBROBLAST+GROWTH+FACTOR+21
3 FGF 21 877258 3% 84% 26 Search FGF+21 Search FGF+21
4 BETA KLOTHO 595985 3% 74% 20 Search BETA+KLOTHO Search BETA+KLOTHO
5 FGF19 528105 4% 41% 32 Search FGF19 Search FGF19
6 FIBROBLAST GROWTH FACTOR 21 FGF21 234059 1% 73% 8 Search FIBROBLAST+GROWTH+FACTOR+21+FGF21 Search FIBROBLAST+GROWTH+FACTOR+21+FGF21
7 FIBROBLAST GROWTH FACTOR 19 121894 1% 30% 10 Search FIBROBLAST+GROWTH+FACTOR+19 Search FIBROBLAST+GROWTH+FACTOR+19
8 KLB 90515 0% 75% 3 Search KLB Search KLB
9 FGF21 RESISTANCE 80459 0% 100% 2 Search FGF21+RESISTANCE Search FGF21+RESISTANCE
10 FGFR1C 80459 0% 100% 2 Search FGFR1C Search FGFR1C

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FISHER, FM , MARATOS-FLIER, E , (2016) UNDERSTANDING THE PHYSIOLOGY OF FGF21.ANNUAL REVIEW OF PHYSIOLOGY, VOL 78. VOL. 78. ISSUE . P. 223 -241 101 93% 11
2 DEGIROLAMO, C , SABBA, C , MOSCHETTA, A , (2016) THERAPEUTIC POTENTIAL OF THE ENDOCRINE FIBROBLAST GROWTH FACTORS FGF19, FGF21 AND FGF23.NATURE REVIEWS DRUG DISCOVERY. VOL. 15. ISSUE 1. P. 51 -69 129 56% 13
3 ZHANG, J , LI, Y , (2015) FIBROBLAST GROWTH FACTOR 21 ANALOGS FOR TREATING METABOLIC DISORDERS.FRONTIERS IN ENDOCRINOLOGY. VOL. 6. ISSUE . P. - 99 93% 4
4 SO, WY , LEUNG, PS , (2016) FIBROBLAST GROWTH FACTOR 21 AS AN EMERGING THERAPEUTIC TARGET FOR TYPE 2 DIABETES MELLITUS.MEDICINAL RESEARCH REVIEWS. VOL. 36. ISSUE 4. P. 672 -704 126 70% 1
5 GIMENO, RE , MOLLER, DE , (2014) FGF21-BASED PHARMACOTHERAPY - POTENTIAL UTILITY FOR METABOLIC DISORDERS.TRENDS IN ENDOCRINOLOGY AND METABOLISM. VOL. 25. ISSUE 6. P. 303 -311 73 96% 49
6 KHARITONENKOV, A , DIMARCHI, R , (2015) FGF21 REVOLUTIONS: RECENT ADVANCES ILLUMINATING FGF21 BIOLOGY AND MEDICINAL PROPERTIES.TRENDS IN ENDOCRINOLOGY AND METABOLISM. VOL. 26. ISSUE 11. P. 608 -617 83 95% 7
7 ZHANG, FF , YU, LC , LIN, XF , CHENG, P , HE, LQ , LI, XK , LU, XM , TAN, Y , YANG, H , CAI, L , ET AL (2015) MINIREVIEW: ROLES OF FIBROBLAST GROWTH FACTORS 19 AND 21 IN METABOLIC REGULATION AND CHRONIC DISEASES.MOLECULAR ENDOCRINOLOGY. VOL. 29. ISSUE 10. P. 1400 -1413 92 88% 5
8 OWEN, BM , MANGELSDORF, DJ , KLIEWER, SA , (2015) TISSUE-SPECIFIC ACTIONS OF THE METABOLIC HORMONES FGF15/19 AND FGF21.TRENDS IN ENDOCRINOLOGY AND METABOLISM. VOL. 26. ISSUE 1. P. 22 -29 69 78% 39
9 MARKAN, KR , POTTHOFF, MJ , (2016) METABOLIC FIBROBLAST GROWTH FACTORS (FGFS): MEDIATORS OF ENERGY HOMEOSTASIS.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 53. ISSUE . P. 85 -93 79 76% 5
10 KHARITONENKOV, A , ADAMS, AC , (2014) INVENTING NEW MEDICINES: THE FGF21 STORY.MOLECULAR METABOLISM. VOL. 3. ISSUE 3. P. 221 -229 70 89% 42

Classes with closest relation at Level 1


Rank Class id link
1 5462 FARNESOID X RECEPTOR//FXR//TGR5
2 10558 FGFR//FIBROBLAST GROWTH FACTOR RECEPTOR 4//FGFR4
3 4071 KLOTHO//FIBROBLAST GROWTH FACTOR 23//FGF23
4 22531 IRISIN//ADROPIN//FNDC5
5 819 BROWN ADIPOSE TISSUE//BROWN ADIPOCYTES//BROWN FAT
6 17034 FETUIN A//ALPHA 2 HS GLYCOPROTEIN//FETUIN
7 16617 BILE ACID MALABSORPTION//SEHCAT//ASBT
8 642 FIBROBLAST GROWTH FACTOR//BASIC FIBROBLAST GROWTH FACTOR//FGF RECEPTOR
9 17101 GLUCAGON RECEPTOR//GLUCAGON RECEPTOR ANTAGONIST//GLUCAGON ANTAGONIST
10 37513 GRP ENERGY METAB//BARNSTABLE BROWN DIABET OBES INTERNAL//CHOLESTEROL TRANSPORT AND EFFLUX

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