Class information for:
Level 1: GILBERTS SYNDROME//UGT1A1//UGT1A1 GENE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14067 795 31.4 75%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
468 3       GLUCOSINOLATES//BILIRUBIN//HEME OXYGENASE 24157
1434 2             BILIRUBIN//HYPERBILIRUBINEMIA//KERNICTERUS 7874
14067 1                   GILBERTS SYNDROME//UGT1A1//UGT1A1 GENE 795

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GILBERTS SYNDROME authKW 3248538 17% 64% 132
2 UGT1A1 authKW 2144044 15% 45% 123
3 UGT1A1 GENE authKW 1038334 4% 97% 28
4 CRIGLER NAJJAR SYNDROME authKW 917170 5% 60% 40
5 UGT1A16 authKW 463636 2% 93% 13
6 UGT1A128 authKW 375718 2% 65% 15
7 CRIGLER NAJJAR SYNDROME TYPE II authKW 345671 1% 100% 9
8 IRINOTECAN authKW 327913 16% 7% 130
9 HYPERBILIRUBINEMIA authKW 290768 9% 10% 74
10 UDP GLUCURONOSYLTRANSFERASE 1A1 authKW 289523 2% 54% 14

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Gastroenterology & Hepatology 2004 16% 0% 125
2 Pediatrics 1240 14% 0% 114
3 Medical Laboratory Technology 740 5% 0% 42
4 Oncology 710 17% 0% 136
5 Pharmacology & Pharmacy 555 17% 0% 139
6 Genetics & Heredity 422 11% 0% 86
7 Hematology 193 6% 0% 44
8 Medicine, Research & Experimental 151 6% 0% 50
9 Medicine, General & Internal 141 8% 0% 62
10 Transplantation 40 2% 0% 15

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 P ONCOL MED 76816 0% 100% 2
2 SOMDETCH PHRA DEBHARATANA MED 76816 0% 100% 2
3 DIGEST SURG SURG ONCOL SURG 2 51205 1% 33% 4
4 AFFILIATED JIASU CANC HOSP 38408 0% 100% 1
5 AFFILIATED SHUGUANG HOSP 38408 0% 100% 1
6 AL AMIRI HOSP MED 38408 0% 100% 1
7 BARCELONA U705 38408 0% 100% 1
8 BEIJING CHAOYANG HOSPC ITAL 38408 0% 100% 1
9 BURLO GAROFOLO CHILDRENS HOSP 38408 0% 100% 1
10 CANCERTEAM EQUIPO INTERDISCIPLINARIO ONCOL 38408 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOGENOMICS JOURNAL 3925 1% 1% 9
2 PHARMACOGENOMICS 3643 2% 1% 13
3 PHARMACOGENETICS 3274 1% 1% 9
4 PHARMACOGENETICS AND GENOMICS 2154 1% 1% 8
5 BLOOD CELLS MOLECULES AND DISEASES 1371 1% 0% 8
6 JOURNAL OF HUMAN GENETICS 1333 1% 0% 9
7 PEDIATRIC RESEARCH 923 2% 0% 15
8 CANCER CHEMOTHERAPY AND PHARMACOLOGY 734 2% 0% 12
9 SEMINARS IN LIVER DISEASE 706 1% 0% 5
10 HEPATOLOGY 704 2% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GILBERTS SYNDROME 3248538 17% 64% 132 Search GILBERTS+SYNDROME Search GILBERTS+SYNDROME
2 UGT1A1 2144044 15% 45% 123 Search UGT1A1 Search UGT1A1
3 UGT1A1 GENE 1038334 4% 97% 28 Search UGT1A1+GENE Search UGT1A1+GENE
4 CRIGLER NAJJAR SYNDROME 917170 5% 60% 40 Search CRIGLER+NAJJAR+SYNDROME Search CRIGLER+NAJJAR+SYNDROME
5 UGT1A16 463636 2% 93% 13 Search UGT1A16 Search UGT1A16
6 UGT1A128 375718 2% 65% 15 Search UGT1A128 Search UGT1A128
7 CRIGLER NAJJAR SYNDROME TYPE II 345671 1% 100% 9 Search CRIGLER+NAJJAR+SYNDROME+TYPE+II Search CRIGLER+NAJJAR+SYNDROME+TYPE+II
8 IRINOTECAN 327913 16% 7% 130 Search IRINOTECAN Search IRINOTECAN
9 HYPERBILIRUBINEMIA 290768 9% 10% 74 Search HYPERBILIRUBINEMIA Search HYPERBILIRUBINEMIA
10 UDP GLUCURONOSYLTRANSFERASE 1A1 289523 2% 54% 14 Search UDP+GLUCURONOSYLTRANSFERASE+1A1 Search UDP+GLUCURONOSYLTRANSFERASE+1A1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CANU, G , MINUCCI, A , ZUPPI, C , CAPOLUONGO, E , (2013) GILBERT AND CRIGLER NAJJAR SYNDROMES: AN UPDATE OF THE UDP-GLUCURONOSYLTRANSFERASE 1A1 (UGT1A1) GENE MUTATION DATABASE.BLOOD CELLS MOLECULES AND DISEASES. VOL. 50. ISSUE 4. P. 273-280 43 96% 24
2 BARTLETT, MG , GOURLEY, GR , (2011) ASSESSMENT OF UGT POLYMORPHISMS AND NEONATAL JAUNDICE.SEMINARS IN PERINATOLOGY. VOL. 35. ISSUE 3. P. 127-133 63 66% 8
3 YU, ZB , ZHU, KC , WANG, L , LIU, Y , SUN, JM , (2015) ASSOCIATION OF NEONATAL HYPERBILIRUBINEMIA WITH UGT1A1 GENE POLYMORPHISMS: A META-ANALYSIS.MEDICAL SCIENCE MONITOR. VOL. 21. ISSUE . P. 3104 -3114 36 88% 2
4 ETIENNE-GRIMALDI, MC , BOYER, JC , THOMAS, F , QUARANTA, S , PICARD, N , LORIOT, MA , NARJOZ, C , PONCET, D , GAGNIEU, MC , GED, C , ET AL (2015) UGT1A1 GENOTYPE AND IRINOTECAN THERAPY: GENERAL REVIEW AND IMPLEMENTATION IN ROUTINE PRACTICE.FUNDAMENTAL & CLINICAL PHARMACOLOGY. VOL. 29. ISSUE 3. P. 219 -237 44 65% 8
5 ATASILP, C , CHANSRIWONG, P , SIRACHAINAN, E , REUNGWETWATTANA, T , CHAMNANPHON, M , PUANGPETCH, A , WONGWAISAYAWAN, S , SUKASEM, C , (2016) CORRELATION OF UGT1A1*28 AND *6 POLYMORPHISMS WITH IRINOTECAN-INDUCED NEUTROPENIA IN THAI COLORECTAL CANCER PATIENTS.DRUG METABOLISM AND PHARMACOKINETICS. VOL. 31. ISSUE 1. P. 90 -94 22 100% 3
6 BOYER, JC , ETIENNE-GRIMALDI, MC , THOMAS, F , QUARANTA, S , PICARD, N , LORIOT, MA , PONCET, D , GAGNIEU, MC , GED, C , BROLY, F , ET AL (2014) INTEREST OF UGT1A1 GENOTYPING WITHIN DIGESTIVE CANCERS TREATMENT BY IRINOTECAN.BULLETIN DU CANCER. VOL. 101. ISSUE 6. P. 533 -553 35 78% 2
7 XU, CL , TANG, XS , QU, YL , KEYOUMU, S , ZHOU, N , TANG, Y , (2016) UGT1A1 GENE POLYMORPHISM IS ASSOCIATED WITH TOXICITY AND CLINICAL EFFICACY OF IRINOTECAN-BASED CHEMOTHERAPY IN PATIENTS WITH ADVANCED COLORECTAL CANCER.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 78. ISSUE 1. P. 119 -130 28 76% 3
8 LI, MM , WANG, ZH , GUO, J , LIU, J , LI, CZ , LIU, L , SHI, H , LIU, LY , LI, HH , XIE, C , ET AL (2014) CLINICAL SIGNIFICANCE OF UGT1A1 GENE POLYMORPHISMS ON IRINOTECAN-BASED REGIMENS AS THE TREATMENT IN METASTATIC COLORECTAL CANCER.ONCOTARGETS AND THERAPY. VOL. 7. ISSUE . P. 1653 -1661 26 87% 12
9 COSTA, E , (2006) HEMATOLOGICALLY IMPORTANT MUTATIONS: BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE GENE MUTATIONS IN GILBERT AND CRIGLER-NAJJAR SYNDROMES.BLOOD CELLS MOLECULES AND DISEASES. VOL. 36. ISSUE 1. P. 77-80 29 100% 18
10 LIU, X , CHENG, D , KUANG, Q , LIU, G , XU, W , (2014) ASSOCIATION OF UGT1A1*28 POLYMORPHISMS WITH IRINOTECAN-INDUCED TOXICITIES IN COLORECTAL CANCER: A META-ANALYSIS IN CAUCASIANS.PHARMACOGENOMICS JOURNAL. VOL. 14. ISSUE 2. P. 120-129 31 62% 29

Classes with closest relation at Level 1


Rank Class id link
1 2545 UDP GLUCURONOSYLTRANSFERASE//GLUCURONIDATION//UDP GLUCURONOSYLTRANSFERASES UGTS
2 16631 BILIRUBIN//BILIVERDIN REDUCTASE//SERUM BILIRUBIN
3 17924 LIVER GROWTH FACTOR//SERV BIOQUIM EXPT//DELTA BILIRUBIN
4 2352 KERNICTERUS//HYPERBILIRUBINEMIA//NEONATAL JAUNDICE
5 33937 ROTOR SYNDROME//BLUE DIVISION//DUBIN JOHNSON
6 1644 CAMPTOTHECIN//SN 38//TOPOTECAN
7 8721 THYMIDYLATE SYNTHASE//DIHYDROPYRIMIDINE DEHYDROGENASE//OROTATE PHOSPHORIBOSYLTRANSFERASE
8 6150 G6PD DEFICIENCY//GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY//G6PD
9 5456 OATP1B1//SLCO1B1//OATP
10 747 METASTATIC COLORECTAL CANCER//OXALIPLATIN//ADVANCED COLORECTAL CANCER

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