Class information for:
Level 1: AFFIBODY MOLECULE//AFFIBODY//BIOMED RADIAT SCI

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13646 822 41.1 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
416 3       NEUROENDOCRINE TUMORS//CARCINOID//SMALL CELL CARCINOMA 28897
808 2             RADIOIMMUNOTHERAPY//NUCLEAR MEDICINE AND BIOLOGY//ANTIBODY DRUG CONJUGATE 12023
13646 1                   AFFIBODY MOLECULE//AFFIBODY//BIOMED RADIAT SCI 822

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AFFIBODY MOLECULE authKW 2832283 10% 89% 86
2 AFFIBODY authKW 1424914 7% 63% 61
3 BIOMED RADIAT SCI address 891638 8% 37% 65
4 UNIT BIOMED RADIAT SCI address 864567 5% 52% 45
5 IMMUNO PET authKW 733720 5% 51% 39
6 ZR 89 authKW 706202 5% 49% 39
7 PRECLIN PET PLATFORM address 654095 5% 46% 38
8 ZIRCONIUM 89 authKW 611305 3% 69% 24
9 COMBINATORIAL PROTEIN ENGINEERING authKW 334310 1% 75% 12
10 RUDBECK address 321585 15% 7% 121

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Radiology, Nuclear Medicine & Medical Imaging 8304 39% 0% 321
2 Oncology 1165 21% 0% 172
3 Biochemical Research Methods 766 11% 0% 90
4 Chemistry, Medicinal 457 8% 0% 63
5 Medicine, Research & Experimental 285 8% 0% 66
6 Biochemistry & Molecular Biology 177 16% 0% 135
7 Nuclear Science & Technology 126 4% 0% 36
8 Chemistry, Organic 124 7% 0% 59
9 Pharmacology & Pharmacy 119 10% 0% 79
10 Chemistry, Inorganic & Nuclear 88 5% 0% 39

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOMED RADIAT SCI 891638 8% 37% 65
2 UNIT BIOMED RADIAT SCI 864567 5% 52% 45
3 PRECLIN PET PLATFORM 654095 5% 46% 38
4 RUDBECK 321585 15% 7% 121
5 PROT TECHNOL 170628 4% 14% 33
6 SECT HOSP PHYS 130005 1% 50% 7
7 HOSP CLIN PHARM 125339 2% 19% 18
8 RADIOCHEM SERV 90999 1% 35% 7
9 ALBANOVA BIOTECHNOL 74292 0% 100% 2
10 TOF PET CT MR 74292 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NUCLEAR MEDICINE 37355 12% 1% 101
2 NUCLEAR MEDICINE AND BIOLOGY 29424 7% 1% 54
3 EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 16734 5% 1% 38
4 MOLECULAR IMAGING AND BIOLOGY 13931 2% 2% 19
5 EJNMMI RESEARCH 10240 1% 3% 11
6 CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 10159 2% 1% 20
7 BIOCONJUGATE CHEMISTRY 7596 4% 1% 32
8 MOLECULAR IMAGING 5256 1% 2% 8
9 THERANOSTICS 3092 1% 1% 7
10 JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 2990 2% 0% 19

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AFFIBODY MOLECULE 2832283 10% 89% 86 Search AFFIBODY+MOLECULE Search AFFIBODY+MOLECULE
2 AFFIBODY 1424914 7% 63% 61 Search AFFIBODY Search AFFIBODY
3 IMMUNO PET 733720 5% 51% 39 Search IMMUNO+PET Search IMMUNO+PET
4 ZR 89 706202 5% 49% 39 Search ZR+89 Search ZR+89
5 ZIRCONIUM 89 611305 3% 69% 24 Search ZIRCONIUM+89 Search ZIRCONIUM+89
6 COMBINATORIAL PROTEIN ENGINEERING 334310 1% 75% 12 Search COMBINATORIAL+PROTEIN+ENGINEERING Search COMBINATORIAL+PROTEIN+ENGINEERING
7 RADIONUCLIDE MOLECULAR IMAGING 222877 1% 100% 6 Search RADIONUCLIDE+MOLECULAR+IMAGING Search RADIONUCLIDE+MOLECULAR+IMAGING
8 HER2 141479 12% 4% 100 Search HER2 Search HER2
9 Y 86 130005 1% 50% 7 Search Y+86 Search Y+86
10 EGF DEXTRAN 118866 0% 80% 4 Search EGF+DEXTRAN Search EGF+DEXTRAN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ALTAI, M , ORLOVA, A , TOLMACHEV, V , (2014) RADIOLABELED PROBES TARGETING TYROSINE-KINASE RECEPTORS FOR PERSONALIZED MEDICINE.CURRENT PHARMACEUTICAL DESIGN. VOL. 20. ISSUE 14. P. 2275-2292 123 51% 1
2 LOFBLOM, J , FELDWISCH, J , TOLMACHEV, V , CARLSSON, J , STAHL, S , FREJD, FY , (2010) AFFIBODY MOLECULES: ENGINEERED PROTEINS FOR THERAPEUTIC, DIAGNOSTIC AND BIOTECHNOLOGICAL APPLICATIONS.FEBS LETTERS. VOL. 584. ISSUE 12. P. 2670 -2680 60 69% 214
3 CORCORAN, EB , HANSON, RN , (2014) IMAGING EGFR AND HER2 BY PET AND SPECT: A REVIEW.MEDICINAL RESEARCH REVIEWS. VOL. 34. ISSUE 3. P. 596-643 83 60% 16
4 VAN DONGEN, GAMS , HUISMAN, MC , BOELLAARD, R , HENDRIKSE, NH , WINDHORST, AD , VISSER, GWM , MOLTHOFF, CFM , VUGTS, DJ , (2015) ZR-89-IMMUNO-PET FOR IMAGING OF LONG CIRCULATING DRUGS AND DISEASE TARGETS: WHY, HOW AND WHEN TO BE APPLIED?.QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. VOL. 59. ISSUE 1. P. 18 -38 66 61% 6
5 FISCHER, G , SEIBOLD, U , SCHIRRMACHER, R , WANGLER, B , WANGLER, C , (2013) ZR-89, A RADIOMETAL NUCLIDE WITH HIGH POTENTIAL FOR MOLECULAR IMAGING WITH PET: CHEMISTRY, APPLICATIONS AND REMAINING CHALLENGES.MOLECULES. VOL. 18. ISSUE 6. P. 6469-6490 53 58% 26
6 AHLGREN, S , TOLMACHEV, V , (2010) RADIONUCLIDE MOLECULAR IMAGING USING AFFIBODY MOLECULES.CURRENT PHARMACEUTICAL BIOTECHNOLOGY. VOL. 11. ISSUE 6. P. 581-589 52 67% 12
7 NYGREN, PA , (2008) ALTERNATIVE BINDING PROTEINS: AFFIBODY BINDING PROTEINS DEVELOPED FROM A SMALL THREE-HELIX BUNDLE SCAFFOLD.FEBS JOURNAL. VOL. 275. ISSUE 11. P. 2668 -2676 40 71% 136
8 WESTERLUND, K , HONARVAR, H , NORRSTROM, E , STRAND, J , MITRAN, B , ORLOVA, A , KARLSTROM, AE , TOLMACHEV, V , (2016) INCREASING THE NET NEGATIVE CHARGE BY REPLACEMENT OF DOTA CHELATOR WITH DOTAGA IMPROVES THE BIODISTRIBUTION OF RADIOLABELED SECOND-GENERATION SYNTHETIC AFFIBODY MOLECULES.MOLECULAR PHARMACEUTICS. VOL. 13. ISSUE 5. P. 1668 -1678 39 75% 0
9 ROSIK, D , THIBBLIN, A , ANTONI, G , HONARVAR, H , STRAND, J , SELVARAJU, RK , ALTAI, M , ORLOVA, A , KARLSTROM, AE , TOLMACHEV, V , (2014) INCORPORATION OF A TRIGLUTAMYL SPACER IMPROVES THE BIODISTRIBUTION OF SYNTHETIC AFFIBODY MOLECULES RADIOFLUORINATED AT THE N-TERMINUS VIA OXIME FORMATION WITH F-18-4-FLUOROBENZALDEHYDE.BIOCONJUGATE CHEMISTRY. VOL. 25. ISSUE 1. P. 82-92 36 78% 5
10 HONARVAR, H , JOKILAAKSO, N , ANDERSSON, K , MALMBERG, J , ROSIK, D , ORLOVA, A , KARLSTROM, AE , TOLMACHEV, V , JARVER, P , (2013) EVALUATION OF BACKBONE-CYCLIZED HER2-BINDING 2-HELIX AFFIBODY MOLECULE FOR IN VIVO MOLECULAR IMAGING.NUCLEAR MEDICINE AND BIOLOGY. VOL. 40. ISSUE 3. P. 378-386 36 80% 5

Classes with closest relation at Level 1


Rank Class id link
1 18905 REPEAT PROTEIN//FN3//ANKYRIN REPEAT
2 28336 RADIOIODINATION//PROSTHETIC RADIOIODINATION//ELED COMPOUND
3 35662 A33 ANTIGEN//ADHESION REGULATING MOLECULE 1//ADRM1
4 12562 FLUORESCENCE GUIDED RESECTION//FLUORESCENCE GUIDED SURGERY//5 ALA
5 18119 PRETARGETING//PRETARGETED RADIOIMMUNOTHERAPY//MOL MED IMMUNOL
6 14481 NANOBODY//SINGLE DOMAIN ANTIBODY//VHH
7 35026 M1B PROSTATE CANCER//BIOMARKER EPIDERMAL GROWTH FACTOR RECEPTOR EGFR//C ERB B 2 NEU GENE
8 3839 EXCITATION FUNCTION//INTEGRAL YIELD//THICK TARGET YIELD
9 11850 AT 211//ASTATINE//TARGETED ALPHA THERAPY
10 4440 NIMOTUZUMAB//CETUXIMAB//EGFR

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