Class information for:
Level 1: AT 211//ASTATINE//TARGETED ALPHA THERAPY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11850 949 33.5 68%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
416 3       NEUROENDOCRINE TUMORS//CARCINOID//SMALL CELL CARCINOMA 28897
808 2             RADIOIMMUNOTHERAPY//NUCLEAR MEDICINE AND BIOLOGY//ANTIBODY DRUG CONJUGATE 12023
11850 1                   AT 211//ASTATINE//TARGETED ALPHA THERAPY 949

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AT 211 authKW 1269168 5% 84% 47
2 ASTATINE authKW 935974 4% 73% 40
3 TARGETED ALPHA THERAPY authKW 887187 4% 77% 36
4 ASTATINE 211 authKW 845305 4% 77% 34
5 RADIOIMMUNOTHERAPY authKW 785468 18% 14% 175
6 BI 213 authKW 659960 3% 71% 29
7 AC 225 authKW 515759 2% 70% 23
8 ACTINIUM 225 authKW 457594 2% 89% 16
9 BISMUTH 213 authKW 450448 1% 100% 14
10 RADIOIMMUNE INORGAN CHEM SECT address 327732 4% 25% 41

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Radiology, Nuclear Medicine & Medical Imaging 11581 43% 0% 406
2 Nuclear Science & Technology 5636 23% 0% 218
3 Chemistry, Inorganic & Nuclear 2328 18% 0% 173
4 Oncology 2308 27% 0% 253
5 Chemistry, Analytical 584 12% 0% 113
6 Biology 185 5% 0% 44
7 Hematology 126 4% 0% 41
8 Medicine, Research & Experimental 121 5% 0% 51
9 Biochemical Research Methods 96 4% 0% 41
10 Pharmacology & Pharmacy 47 7% 0% 65

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RADIOIMMUNE INORGAN CHEM SECT 327732 4% 25% 41
2 CYCLOTRON PET UNIT 186148 1% 64% 9
3 TRANSURANIUM ELEMENTS 142374 8% 6% 76
4 RADIAT ONCOL BRANCH 132229 6% 8% 53
5 NANTES ANGERS CANC CRCNA 128699 0% 100% 4
6 INORGAN RADIOIMMUNE CHEM SECT 96525 0% 100% 3
7 CERO 72392 0% 75% 3
8 ADDENBROOKES HOSP CLIN MED RADIOTHER EUT 64350 0% 100% 2
9 EXPT RADIAT ONCOL 46905 3% 4% 33
10 CARST 36766 0% 29% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 30159 4% 3% 37
2 NUCLEAR MEDICINE AND BIOLOGY 26426 6% 1% 55
3 RADIOCHIMICA ACTA 12736 4% 1% 40
4 APPLIED RADIATION AND ISOTOPES 10484 6% 1% 54
5 RADIOCHEMICAL AND RADIOANALYTICAL LETTERS 9826 1% 2% 14
6 JOURNAL OF NUCLEAR MEDICINE 6656 5% 0% 46
7 ANTIBODY IMMUNOCONJUGATES AND RADIOPHARMACEUTICALS 4895 1% 3% 5
8 JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-LETTERS 4862 2% 1% 16
9 RADIATION RESEARCH 4368 3% 0% 30
10 JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 3575 4% 0% 35

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AT 211 1269168 5% 84% 47 Search AT+211 Search AT+211
2 ASTATINE 935974 4% 73% 40 Search ASTATINE Search ASTATINE
3 TARGETED ALPHA THERAPY 887187 4% 77% 36 Search TARGETED+ALPHA+THERAPY Search TARGETED+ALPHA+THERAPY
4 ASTATINE 211 845305 4% 77% 34 Search ASTATINE+211 Search ASTATINE+211
5 RADIOIMMUNOTHERAPY 785468 18% 14% 175 Search RADIOIMMUNOTHERAPY Search RADIOIMMUNOTHERAPY
6 BI 213 659960 3% 71% 29 Search BI+213 Search BI+213
7 AC 225 515759 2% 70% 23 Search AC+225 Search AC+225
8 ACTINIUM 225 457594 2% 89% 16 Search ACTINIUM+225 Search ACTINIUM+225
9 BISMUTH 213 450448 1% 100% 14 Search BISMUTH+213 Search BISMUTH+213
10 ALPHA EMITTER BI 213 321748 1% 100% 10 Search ALPHA+EMITTER+BI+213 Search ALPHA+EMITTER+BI+213

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SEIDL, C , (2014) RADIOIMMUNOTHERAPY WITH A- PARTICLE- EMITTING RADIONUCLIDES.IMMUNOTHERAPY. VOL. 6. ISSUE 4. P. 431 -458 121 81% 9
2 KIM, YS , BRECHBIEL, MW , (2012) AN OVERVIEW OF TARGETED ALPHA THERAPY.TUMOR BIOLOGY. VOL. 33. ISSUE 3. P. 573-590 90 91% 38
3 GUERARD, F , GESTIN, JF , BRECHBIEL, MW , (2013) PRODUCTION OF [AT-211]-ASTATINATED RADIOPHARMACEUTICALS AND APPLICATIONS IN TARGETED ALPHA-PARTICLE THERAPY.CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS. VOL. 28. ISSUE 1. P. 1 -20 80 81% 8
4 HUCLIER-MARKAI, S , ALLIOT, C , VARMENOT, N , CUTLER, CS , BARBET, J , (2012) ALPHA-EMITTERS FOR IMMUNO-THERAPY: A REVIEW OF RECENT DEVELOPMENTS FROM CHEMISTRY TO CLINICS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 12. ISSUE 23. P. 2642-2654 78 82% 6
5 COUTURIER, O , SUPIOT, S , DEGRAEF-MOUGIN, M , FAIVRE-CHAUVET, A , CARLIER, T , CHATAL, JF , DAVODEAU, F , CHEREL, M , (2005) CANCER RADIOIMMUNOTHERAPY WITH ALPHA-EMITTING NUCLIDES.EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. VOL. 32. ISSUE 5. P. 601-614 90 74% 83
6 DEKEMPENEER, Y , KEYAERTS, M , KRASNIQI, A , PUTTEMANS, J , MUYLDERMANS, S , LAHOUTTE, T , D'HUYVETTER, M , DEVOOGDT, N , (2016) TARGETED ALPHA THERAPY USING SHORT-LIVED ALPHA-PARTICLES AND THE PROMISE OF NANOBODIES AS TARGETING VEHICLE.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 16. ISSUE 8. P. 1035 -1047 54 61% 1
7 BRECHBIEL, MW , (2007) TARGETED ALPHA-THERAPY: PAST, PRESENT, FUTURE?.DALTON TRANSACTIONS. VOL. . ISSUE 43. P. 4918 -4928 54 71% 43
8 ZALUTSKY, MR , POZZI, OR , (2004) RADIOIMMUNOTHERAPY WITH ALPHA-PARTICLE EMITTING RADIONUCLIDES.QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. VOL. 48. ISSUE 4. P. 289 -296 44 83% 46
9 ZALUTSKY, MR , VAIDYANATHAN, G , (2000) ASTATINE-211-LABELED RADIOTHERAPEUTICS: AN EMERGING APPROACH TO TARGETED ALPHA-PARTICLE RADIOTHERAPY.CURRENT PHARMACEUTICAL DESIGN. VOL. 6. ISSUE 14. P. 1433 -1455 52 71% 103
10 ESSLER, M , GARTNER, FC , NEFF, F , BLECHERT, B , SENEKOWITSCH-SCHMIDTKE, R , BRUCHERTSEIFER, F , MORGENSTERN, A , SEIDL, C , (2012) THERAPEUTIC EFFICACY AND TOXICITY OF AC-225-LABELLED VS. BI-213-LABELLED TUMOUR-HOMING PEPTIDES IN A PRECLINICAL MOUSE MODEL OF PERITONEAL CARCINOMATOSIS.EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. VOL. 39. ISSUE 4. P. 602 -612 33 85% 14

Classes with closest relation at Level 1


Rank Class id link
1 28336 RADIOIODINATION//PROSTHETIC RADIOIODINATION//ELED COMPOUND
2 15894 AUGER ELECTRONS//AUGER ELECTRON EMITTERS//CELLULAR DOSIMETRY
3 18119 PRETARGETING//PRETARGETED RADIOIMMUNOTHERAPY//MOL MED IMMUNOL
4 35662 A33 ANTIGEN//ADHESION REGULATING MOLECULE 1//ADRM1
5 411 RADIOIMMUNOTHERAPY//ANTIBODY IMMUNOCONJUGATES AND RADIOPHARMACEUTICALS//IMMUNOSCINTIGRAPHY
6 9580 BONE PAIN PALLIATION//STRONTIUM 89//PAIN PALLIATION
7 3839 EXCITATION FUNCTION//INTEGRAL YIELD//THICK TARGET YIELD
8 20544 MELANOMA IMAGING//IMAGERIE MOL THER IE VECTORISEE//ALPHA MELANOCYTE STIMULATING HORMONE HYBRID PEPTIDE
9 13646 AFFIBODY MOLECULE//AFFIBODY//BIOMED RADIAT SCI
10 36939 ARYLMERCURIALS//ARYLMERCURIC CHLORIDES//ARYLMERCURIC HALIDES

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