Class information for:
Level 1: INTEIN//PROTEIN SPLICING//HOMING ENDONUCLEASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11925 944 41.3 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
478 3       PHAGE DISPLAY//CELL FREE PROTEIN SYNTHESIS//ANTIBODY ENGINEERING 23687
1537 2             CELL FREE PROTEIN SYNTHESIS//INTEIN//PROTEIN SPLICING 7453
11925 1                   INTEIN//PROTEIN SPLICING//HOMING ENDONUCLEASE 944

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTEIN authKW 2979166 17% 56% 164
2 PROTEIN SPLICING authKW 2577724 11% 79% 101
3 HOMING ENDONUCLEASE authKW 1021373 6% 53% 60
4 SPLIT INTEIN authKW 445126 2% 81% 17
5 EXTEIN authKW 355798 1% 100% 11
6 PROTEIN TRANS SPLICING authKW 288157 1% 64% 14
7 INTRON HOMING authKW 217424 1% 61% 11
8 SYNTHET PROT CHEM address 192220 2% 26% 23
9 PROTEIN LIGATION authKW 176085 1% 39% 14
10 EXPRESSED PROTEIN LIGATION authKW 145527 2% 25% 18

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 6687 68% 0% 642
2 Biotechnology & Applied Microbiology 569 12% 0% 110
3 Biochemical Research Methods 453 8% 0% 77
4 Biophysics 403 8% 0% 80
5 Genetics & Heredity 401 10% 0% 93
6 Cell Biology 310 11% 0% 105
7 Microbiology 114 6% 0% 57
8 Mycology 59 1% 0% 11
9 Chemistry, Multidisciplinary 44 8% 0% 72
10 Evolutionary Biology 25 1% 0% 14

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SYNTHET PROT CHEM 192220 2% 26% 23
2 MACROMOL CRYSTALLOG GRP 99417 2% 18% 17
3 PROGRAM STRUCT BIOL BIOPHYS 73254 2% 13% 18
4 PROGRAM MOL BIOPHYS STRUCT DESIGN 72775 0% 75% 3
5 ADOLF BUTENANDT NEUROBIOCHEM 32345 0% 100% 1
6 BASKIN COMP ENGN INFORMAT SCI 32345 0% 100% 1
7 BIO OURCE BIOENVIRONM SCI GENET 32345 0% 100% 1
8 BIOARCHITECT GRP CELLULAR MOL BIOL 32345 0% 100% 1
9 BIOMED IRBPROGRAM COMPUTAT BIOL 32345 0% 100% 1
10 CELLECTIS GENOME SURG 32345 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NUCLEIC ACIDS RESEARCH 9308 11% 0% 107
2 JOURNAL OF MOLECULAR BIOLOGY 3273 5% 0% 49
3 MOBILE DNA 1897 0% 2% 3
4 PROTEIN EXPRESSION AND PURIFICATION 1764 2% 0% 16
5 BIOMOLECULAR NMR ASSIGNMENTS 1656 1% 1% 6
6 PROTEIN SCIENCE 1642 2% 0% 18
7 PROTEIN AND PEPTIDE LETTERS 1525 1% 0% 11
8 PROTEIN ENGINEERING DESIGN & SELECTION 1513 1% 1% 7
9 ADVANCES IN BIOPHYSICS 1240 0% 2% 2
10 JOURNAL OF BIOLOGICAL CHEMISTRY 1073 8% 0% 74

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INTEIN 2979166 17% 56% 164 Search INTEIN Search INTEIN
2 PROTEIN SPLICING 2577724 11% 79% 101 Search PROTEIN+SPLICING Search PROTEIN+SPLICING
3 HOMING ENDONUCLEASE 1021373 6% 53% 60 Search HOMING+ENDONUCLEASE Search HOMING+ENDONUCLEASE
4 SPLIT INTEIN 445126 2% 81% 17 Search SPLIT+INTEIN Search SPLIT+INTEIN
5 EXTEIN 355798 1% 100% 11 Search EXTEIN Search EXTEIN
6 PROTEIN TRANS SPLICING 288157 1% 64% 14 Search PROTEIN+TRANS+SPLICING Search PROTEIN+TRANS+SPLICING
7 INTRON HOMING 217424 1% 61% 11 Search INTRON+HOMING Search INTRON+HOMING
8 PROTEIN LIGATION 176085 1% 39% 14 Search PROTEIN+LIGATION Search PROTEIN+LIGATION
9 EXPRESSED PROTEIN LIGATION 145527 2% 25% 18 Search EXPRESSED+PROTEIN+LIGATION Search EXPRESSED+PROTEIN+LIGATION
10 INTRON HOMING SITE 129381 0% 100% 4 Search INTRON+HOMING+SITE Search INTRON+HOMING+SITE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VOLKMANN, G , MOOTZ, HD , (2013) RECENT PROGRESS IN INTEIN RESEARCH: FROM MECHANISM TO DIRECTED EVOLUTION AND APPLICATIONS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 70. ISSUE 7. P. 1185 -1206 114 90% 36
2 MILLS, KV , JOHNSON, MA , PERLER, FB , (2014) PROTEIN SPLICING: HOW INTEINS ESCAPE FROM PRECURSOR PROTEINS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 289. ISSUE 21. P. 14498 -14505 96 96% 14
3 SHAH, NH , MUIR, TW , (2014) INTEINS: NATURE'S GIFT TO PROTEIN CHEMISTS.CHEMICAL SCIENCE. VOL. 5. ISSUE 2. P. 446-461 84 78% 40
4 LI, YF , (2015) SPLIT-INTEINS AND THEIR BIOAPPLICATIONS.BIOTECHNOLOGY LETTERS. VOL. 37. ISSUE 11. P. 2121 -2137 91 84% 5
5 TOPILINA, NI , MILLS, KV , (2014) RECENT ADVANCES IN IN VIVO APPLICATIONS OF INTEIN-MEDIATED PROTEIN SPLICING.MOBILE DNA. VOL. 5. ISSUE . P. - 94 74% 14
6 ARANKO, AS , WLODAWER, A , IWAI, H , (2014) NATURE'S RECIPE FOR SPLITTING INTEINS.PROTEIN ENGINEERING DESIGN & SELECTION. VOL. 27. ISSUE 8. P. 263 -271 68 99% 8
7 GUHAN, N , MUNIYAPPA, K , (2003) STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF HOMING ENDONUCLEASES.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 38. ISSUE 3. P. 199-248 142 60% 17
8 LIU, XQ , (2000) PROTEIN-SPLICING INTEIN: GENETIC MOBILITY, ORIGIN, AND EVOLUTION.ANNUAL REVIEW OF GENETICS. VOL. 34. ISSUE . P. 61-76 73 96% 93
9 STODDARD, BL , (2014) HOMING ENDONUCLEASES FROM MOBILE GROUP I INTRONS: DISCOVERY TO GENOME ENGINEERING.MOBILE DNA. VOL. 5. ISSUE . P. - 73 62% 17
10 STODDARD, BL , (2011) HOMING ENDONUCLEASES: FROM MICROBIAL GENETIC INVADERS TO REAGENTS FOR TARGETED DNA MODIFICATION.STRUCTURE. VOL. 19. ISSUE 1. P. 7 -15 59 69% 104

Classes with closest relation at Level 1


Rank Class id link
1 4185 GROUP I INTRON//RIBOZYME//SELF SPLICING
2 5605 NATIVE CHEMICAL LIGATION//PEPTIDE THIOESTER//DIFFICULT SEQUENCE
3 7116 PODOSPORA ANSERINA//CURRENT GENETICS//MITOCHONDRIAL PLASMID
4 26233 PLECTASIN//JIANGSU SUPERMOL MED MAT PLICAT//FUSION EXPRESSION
5 18097 GENE UVSX//BACTERIOPHAGE T4//UVSX
6 32602 KAUFFMANN WHITE SCHEME//I CEUI//HMU UCFM INFECT GENOM
7 19599 MOL BIOSENSOR IMAGING//FLUOROGEN ACTIVATING PROTEIN//FLUOROGEN
8 27062 ASPARTYLGLUCOSAMINURIA//GLYCOSYLASPARAGINASE//ASPARTYLGLUCOSAMINIDASE
9 22981 ENDO EXONUCLEASE//EXTRACELLULAR NUCLEASE//NUCLEASE
10 14228 BIMOLECULAR FLUORESCENCE COMPLEMENTATION//SPLIT UBIQUITIN//PROTEIN FRAGMENT COMPLEMENTATION ASSAY

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