Class information for:
Level 1: 5 HT7 RECEPTOR//5 HT6 RECEPTOR//5 HT6

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11145 1005 47.5 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
76 3       NEUROSCIENCES//DOPAMINE//SEROTONIN 81359
218 2             SEROTONIN//5 HT1A RECEPTOR//5 HT2A RECEPTOR 20633
11145 1                   5 HT7 RECEPTOR//5 HT6 RECEPTOR//5 HT6 1005

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 5 HT7 RECEPTOR authKW 2622681 13% 64% 134
2 5 HT6 RECEPTOR authKW 2586742 9% 90% 95
3 5 HT6 authKW 992457 4% 78% 42
4 5 HT6 RECEPTOR ANTAGONIST authKW 708207 3% 90% 26
5 5 HT7 authKW 702162 4% 54% 43
6 SB 271046 authKW 546874 2% 100% 18
7 SB 269970 authKW 499984 2% 69% 24
8 5 HT6 ANTAGONIST authKW 486111 2% 100% 16
9 5 HT7 RECEPTOR ANTAGONIST authKW 366751 1% 93% 13
10 5 HT5A RECEPTOR authKW 312496 1% 86% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 7573 26% 0% 261
2 Neurosciences 4870 41% 0% 412
3 Pharmacology & Pharmacy 4030 38% 0% 379
4 Behavioral Sciences 1165 8% 0% 81
5 Chemistry, Organic 635 13% 0% 128
6 Psychiatry 454 9% 0% 87
7 Biochemistry & Molecular Biology 87 12% 0% 125
8 Clinical Neurology 21 4% 0% 37
9 Psychology 11 1% 0% 12
10 Psychology, Multidisciplinary 1 1% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BEHAV NEUROSCI DRUG DEV 152483 2% 31% 16
2 DISCOVERY DRUG METAB PHAMACOKINET 60764 0% 100% 2
3 O FARMACOBIOL 54685 0% 60% 3
4 IFRNS 70 40508 0% 67% 2
5 PRINTING MEDIA 40508 0% 67% 2
6 PRBD N 40504 0% 33% 4
7 PSYCHIAT EXCELLENCE DRUG DISCOVERY 33756 1% 9% 13
8 ABT NEUROL SINNESPHYSIOL 30382 0% 100% 1
9 AMINOACIDS PEPTIDES PROT 30382 0% 100% 1
10 BIOMOL MAX MOUSSERON AMINO ACIDS PEPTID 30382 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 8044 8% 0% 82
2 NEUROPHARMACOLOGY 6522 4% 0% 45
3 REVIEWS IN THE NEUROSCIENCES 6345 1% 2% 12
4 INTERNATIONAL REVIEW OF NEUROBIOLOGY 5773 1% 1% 15
5 BEHAVIOURAL BRAIN RESEARCH 4604 4% 0% 40
6 JOURNAL OF MEDICINAL CHEMISTRY 3339 5% 0% 49
7 BIOORGANIC & MEDICINAL CHEMISTRY 2983 4% 0% 36
8 BRITISH JOURNAL OF PHARMACOLOGY 2969 4% 0% 42
9 PHARMACOLOGICAL REPORTS 2033 1% 1% 11
10 NEUROPSYCHOPHARMACOLOGY 1912 2% 0% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 5 HT7 RECEPTOR 2622681 13% 64% 134 Search 5+HT7+RECEPTOR Search 5+HT7+RECEPTOR
2 5 HT6 RECEPTOR 2586742 9% 90% 95 Search 5+HT6+RECEPTOR Search 5+HT6+RECEPTOR
3 5 HT6 992457 4% 78% 42 Search 5+HT6 Search 5+HT6
4 5 HT6 RECEPTOR ANTAGONIST 708207 3% 90% 26 Search 5+HT6+RECEPTOR+ANTAGONIST Search 5+HT6+RECEPTOR+ANTAGONIST
5 5 HT7 702162 4% 54% 43 Search 5+HT7 Search 5+HT7
6 SB 271046 546874 2% 100% 18 Search SB+271046 Search SB+271046
7 SB 269970 499984 2% 69% 24 Search SB+269970 Search SB+269970
8 5 HT6 ANTAGONIST 486111 2% 100% 16 Search 5+HT6+ANTAGONIST Search 5+HT6+ANTAGONIST
9 5 HT7 RECEPTOR ANTAGONIST 366751 1% 93% 13 Search 5+HT7+RECEPTOR+ANTAGONIST Search 5+HT7+RECEPTOR+ANTAGONIST
10 5 HT5A RECEPTOR 312496 1% 86% 12 Search 5+HT5A+RECEPTOR Search 5+HT5A+RECEPTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MARAZZITI, D , BARONI, S , DELL'OSSO, MC , BORDI, F , BORSINI, F , (2011) SEROTONIN RECEPTORS OF TYPE 6 (5-HT6): WHAT CAN WE EXPECT FROM THEM?.CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 18. P. 2783 -2790 140 86% 15
2 MARAZZITI, D , BARONI, S , BORSINI, F , PICCHETTI, M , VATTERONI, E , FALASCHI, V , CATENA-DELL'OSSO, M , (2013) SEROTONIN RECEPTORS OF TYPE 6 (5-HT6): FROM NEUROSCIENCE TO CLINICAL PHARMACOLOGY.CURRENT MEDICINAL CHEMISTRY. VOL. 20. ISSUE 3. P. 371-377 130 87% 10
3 NIKIFORUK, A , (2015) TARGETING THE SEROTONIN 5-HT7 RECEPTOR IN THE SEARCH FOR TREATMENTS FOR CNS DISORDERS: RATIONALE AND PROGRESS TO DATE.CNS DRUGS. VOL. 29. ISSUE 4. P. 265 -275 94 91% 16
4 BENHAMU, B , MARTIN-FONTECHA, M , VAZQUEZ-VILLA, H , PARDO, L , LOPEZ-RODRIGUEZ, ML , (2014) SEROTONIN 5-HT6 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF COGNITIVE DEFICIENCY IN ALZHEIMER'S DISEASE.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 17. P. 7160 -7181 107 82% 28
5 LEOPOLDO, M , LACIVITA, E , BERARDI, F , PERRONE, R , HEDLUND, PB , (2011) SEROTONIN 5-HT7 RECEPTOR AGENTS: STRUCTURE-ACTIVITY RELATIONSHIPS AND POTENTIAL THERAPEUTIC APPLICATIONS IN CENTRAL NERVOUS SYSTEM DISORDERS.PHARMACOLOGY & THERAPEUTICS. VOL. 129. ISSUE 2. P. 120-148 133 64% 67
6 SHIREMAN, BT , BONAVENTURE, P , CARRUTHERS, NI , (2008) RECENT ADVANCES ON THE 5-HT5A, 5-HT6 AND 5-HT7 RECEPTORS.ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 43. VOL. 43. ISSUE . P. 25-42 113 87% 8
7 BALI, A , SINGH, S , (2015) SEROTONERGIC 5-HT6 RECEPTOR ANTAGONISTS: HETEROCYCLIC CHEMISTRY AND POTENTIAL THERAPEUTIC SIGNIFICANCE.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 15. ISSUE 17. P. 1643 -1662 86 76% 6
8 LIU, KG , ROBICHAUD, AJ , (2010) 5-HT6 MEDICINAL CHEMISTRY.PHARMACOLOGY OF 5-HT6 RECEPTORS, PT 1. VOL. 94. ISSUE . P. 1-34 77 96% 30
9 PITTALA, V , SALERNO, L , MODICA, M , SIRACUSA, MA , ROMEO, G , (2007) 5-HT7 RECEPTOR LIGANDS: RECENT DEVELOPMENTS AND POTENTIAL THERAPEUTIC APPLICATIONS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 7. ISSUE 9. P. 945-960 104 76% 33
10 KARILA, D , FRERET, T , BOUET, V , BOULOUARD, M , DALLEMAGNE, P , ROCHAIS, C , (2015) THERAPEUTIC POTENTIAL OF 5-HT6 RECEPTOR AGONISTS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 58. ISSUE 20. P. 7901 -7912 68 88% 5

Classes with closest relation at Level 1


Rank Class id link
1 32254 VORTIOXETINE//LU AA21004//BIS ARYL SULFANYLA MINE
2 20838 SEROTONIN MODULATED ANTICONSOLIDATION PROTEIN//UMR 7521LN2C//3 2 CARBOXYPIPERAZIN 4 YLPROPYL 1 PHOSPHONIC ACID
3 28623 DIMEBON//LATREPIRDINE//DIMEBOLIN
4 18005 ARYLPIPERAZINES//5 HT1A LIGANDS//LONG CHAIN ARYLPIPERAZINES
5 11921 5 HT1B RECEPTOR//5 HT MODULINE//UNITE PHARMACOL NEUROIMMUNOENDOCRINIENNE
6 3578 5 HT2C RECEPTOR//5 HT2A RECEPTOR//5 HT2C
7 7516 5 HT4 RECEPTOR//5 HT4//GR 113808
8 15628 F 13640//POLYSYNAPTIC REFLEX//5 HT RECEPTOR SUBTYPE
9 20744 ASENAPINE//ZIPRASIDONE//LURASIDONE
10 12327 ARIPIPRAZOLE//BLONANSERIN//CONDITIONED AVOIDANCE RESPONSE

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