Class information for:
Level 1: DIMEBON//LATREPIRDINE//DIMEBOLIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
28623 203 30.1 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
1 4 ECONOMICS//EDUCATION & EDUCATIONAL RESEARCH//PSYCHOL 3876184
110 3       PSYCHIATRY//SCHIZOPHRENIA//BIPOLAR DISORDER 71389
3387 2             DIMEBON//REMOXIPRIDE//LATREPIRDINE 1644
28623 1                   DIMEBON//LATREPIRDINE//DIMEBOLIN 203

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIMEBON authKW 3285308 15% 70% 31
2 LATREPIRDINE authKW 1367460 5% 91% 10
3 DIMEBOLIN authKW 962690 4% 80% 8
4 NEURONAL NMDA RECEPTORS authKW 752104 2% 100% 5
5 GAMMA CARBOLINES authKW 676885 4% 50% 9
6 CYCLOALKANEINDOLE authKW 451262 1% 100% 3
7 1 2 3 4 4A 9B HEXAHYDRO GAMMA CARBOLINES authKW 300842 1% 100% 2
8 1 2 3 4 TETRAHYDRO authKW 300842 1% 100% 2
9 1 2 AND 3 4 DIHYDRO authKW 300842 1% 100% 2
10 1 3 7 BISDIMETHYLAMINOPHENOTHIAZIN 10 YLPROPENONE authKW 300842 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 691 18% 0% 36
2 Pharmacology & Pharmacy 331 25% 0% 51
3 Chemistry, Organic 225 16% 0% 33
4 Chemistry, Multidisciplinary 207 23% 0% 46
5 Neurosciences 148 18% 0% 36
6 Psychiatry 45 6% 0% 13
7 Medicine, Research & Experimental 40 6% 0% 13
8 Toxicology 23 4% 0% 8
9 Clinical Neurology 20 6% 0% 12
10 Biochemistry & Molecular Biology 3 8% 0% 17

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL BIOL HIGH THROUGHPUT SCREENING 200560 1% 67% 2
2 MOL STEM CELL PHARMACOL 193395 1% 43% 3
3 BIOMAT CEIB 150421 0% 100% 1
4 DPTO CIENCIAS MED FARMACOL 150421 0% 100% 1
5 FOOD SCI FOODS NUTR 150421 0% 100% 1
6 MOOR SIDE UNIT 150421 0% 100% 1
7 SUPER COMP ENERGY ENVIRONM 150421 0% 100% 1
8 VET AFFAIRS PREVENT TREATMENT VISUAL L 150421 0% 100% 1
9 PHYSIOL ACT CPDS 83566 8% 3% 17
10 PHYSIOLOGICALLY ACT CPDS 65214 3% 6% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FARMAKOLOGIYA I TOKSIKOLOGIYA 3093 2% 0% 5
2 MOLECULAR NEURODEGENERATION 2420 1% 1% 3
3 CHEMISTRY OF HETEROCYCLIC COMPOUNDS 2342 2% 0% 5
4 JOURNAL OF ALZHEIMERS DISEASE 2120 4% 0% 8
5 BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE 1925 6% 0% 13
6 RUSSIAN CHEMICAL BULLETIN 1583 5% 0% 10
7 INTERNATIONAL PHARMACOPSYCHIATRY 1378 0% 1% 1
8 CNS SPECTRUMS 1244 1% 0% 3
9 PHARMACEUTICAL CHEMISTRY JOURNAL 1215 1% 0% 3
10 KHIMIKO-FARMATSEVTICHESKII ZHURNAL 935 2% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DIMEBON 3285308 15% 70% 31 Search DIMEBON Search DIMEBON
2 LATREPIRDINE 1367460 5% 91% 10 Search LATREPIRDINE Search LATREPIRDINE
3 DIMEBOLIN 962690 4% 80% 8 Search DIMEBOLIN Search DIMEBOLIN
4 NEURONAL NMDA RECEPTORS 752104 2% 100% 5 Search NEURONAL+NMDA+RECEPTORS Search NEURONAL+NMDA+RECEPTORS
5 GAMMA CARBOLINES 676885 4% 50% 9 Search GAMMA+CARBOLINES Search GAMMA+CARBOLINES
6 CYCLOALKANEINDOLE 451262 1% 100% 3 Search CYCLOALKANEINDOLE Search CYCLOALKANEINDOLE
7 1 2 3 4 4A 9B HEXAHYDRO GAMMA CARBOLINES 300842 1% 100% 2 Search 1+2+3+4+4A+9B+HEXAHYDRO+GAMMA+CARBOLINES Search 1+2+3+4+4A+9B+HEXAHYDRO+GAMMA+CARBOLINES
8 1 2 3 4 TETRAHYDRO 300842 1% 100% 2 Search 1+2+3+4+TETRAHYDRO Search 1+2+3+4+TETRAHYDRO
9 1 2 AND 3 4 DIHYDRO 300842 1% 100% 2 Search 1+2+AND+3+4+DIHYDRO Search 1+2+AND+3+4+DIHYDRO
10 1 3 7 BISDIMETHYLAMINOPHENOTHIAZIN 10 YLPROPENONE 300842 1% 100% 2 Search 1+3+7+BISDIMETHYLAMINOPHENOTHIAZIN+10+YLPROPENONE Search 1+3+7+BISDIMETHYLAMINOPHENOTHIAZIN+10+YLPROPENONE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CANO-CUENCA, N , DEL POZO, JSG , JORDAN, J , (2015) LATREPIRDINE: A SYSTEMATIC REVIEW OF THE PRECLINICAL STUDIES.REVISTA DE NEUROLOGIA. VOL. 60. ISSUE 1. P. 35 -42 31 67% 0
2 PETERS, OM , SHELKOVNIKOVA, T , TARASOVA, T , SPRINGE, S , KUKHARSKY, MS , SMITH, GA , BROOKS, S , KOZIN, SA , KOTELEVTSEVE, Y , BACHURIN, SO , ET AL (2013) CHRONIC ADMINISTRATION OF DIMEBON DOES NOT AMELIORATE AMYLOID-BETA PATHOLOGY IN 5XFAD TRANSGENIC MICE.JOURNAL OF ALZHEIMERS DISEASE. VOL. 36. ISSUE 3. P. 589-596 20 87% 8
3 USTYUGOV, A , SHEVTSOVA, E , BACHURIN, S , (2015) NOVEL SITES OF NEUROPROTECTIVE ACTION OF DIMEBON (LATREPIRDINE).MOLECULAR NEUROBIOLOGY. VOL. 52. ISSUE 2. P. 970 -978 28 56% 1
4 LOUDERBACK, KM , WILLS, TA , MUGLIA, LJ , WINDER, DG , (2013) KNOCKDOWN OF BNST GLUN2B-CONTAINING NMDA RECEPTORS MIMICS THE ACTIONS OF KETAMINE ON NOVELTY-INDUCED HYPOPHAGIA.TRANSLATIONAL PSYCHIATRY. VOL. 3. ISSUE . P. - 33 49% 4
5 ALEKSEYEV, RS , KURKIN, AV , YUROVSKAYA, MA , (2011) GAMMA-CARBOLINES AND THEIR HYDROGENATED DERIVATIVES 3.* HYDROGENATED DERIVATIVES OF GAMMA-CARBOLINES: CHEMICAL AND BIOLOGICAL POPERTIES (REVIEW).CHEMISTRY OF HETEROCYCLIC COMPOUNDS. VOL. 46. ISSUE 10. P. 1169 -1198 25 44% 4
6 IVACHTCHENKO, AV , FROLOV, EB , MITKIN, OD , TKACHENKO, SE , KHVAT, A , (2010) SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL BIOISOSTERIC ANALOGUES OF DIMEBON (TM).LETTERS IN DRUG DESIGN & DISCOVERY. VOL. 7. ISSUE 6. P. 446-451 13 87% 1
7 SOKOLOV, VB , AKSINENKO, AY , EPISHINA, TA , GOREVA, TV , (2016) CATALYTIC ALKYLATION OF SUBSTITUTED INDOLES WITH (PHENOTHIAZIN-10-YL)PROPENE-1-ONES.RUSSIAN JOURNAL OF GENERAL CHEMISTRY. VOL. 86. ISSUE 5. P. 1028 -1031 11 85% 0
8 PETERS, OM , CONNOR-ROBSON, N , SOKOLOV, VB , AKSINENKO, AY , KUKHARSKY, MS , BACHURIN, SO , NINKINA, N , BUCHMAN, VL , (2013) CHRONIC ADMINISTRATION OF DIMEBON AMELIORATES PATHOLOGY IN TAU(P301S) TRANSGENIC MICE.JOURNAL OF ALZHEIMERS DISEASE. VOL. 33. ISSUE 4. P. 1041-1049 16 48% 19
9 BACHURIN, SO , SHELKOVNIKOVA, TA , USTYUGOV, AA , PETERS, O , KHRITANKOVA, I , AFANASIEVA, MA , TARASOVA, TV , ALENTOV, II , BUCHMAN, VL , NINKINA, NN , (2012) DIMEBON SLOWS PROGRESSION OF PROTEINOPATHY IN GAMMA-SYNUCLEIN TRANSGENIC MICE.NEUROTOXICITY RESEARCH. VOL. 22. ISSUE 1. P. 33 -42 17 44% 17
10 CANO-CUENCA, N , POZOC, JESG , JORDAN, J , (2014) EVIDENCE FOR THE EFFICACY OF LATREPIRDINE (DIMEBON) TREATMENT FOR IMPROVEMENT OF COGNITIVE FUNCTION: A META-ANALYSIS.JOURNAL OF ALZHEIMERS DISEASE. VOL. 38. ISSUE 1. P. 155-164 13 46% 12

Classes with closest relation at Level 1


Rank Class id link
1 11145 5 HT7 RECEPTOR//5 HT6 RECEPTOR//5 HT6
2 22258 REMOXIPRIDE//AGONIST ANTAGONIST INTERACTION MODEL//1 2 DIAMINOCYCLOPROPANE
3 36950 NPAS4//NPAS3//LE PAS
4 10591 STUDY NEURODEGENERAT DIS//BURKE MED//MITOCHONDRIA
5 32667 CARDIAC ANTIARRHYTHMICS//CARDIOVASCULAR DISEASES PSYCHOLOGY//F ALKYLOXIRANE
6 29377 AZECINES//LE300//LEHRSTUHL PHARMAZEUT MED CHEM
7 27240 PYRIDO3 2 BINDOLES//3 N ARYL N CHLOROACETYLAMINO 2 FORMYLINDOLES//SCI ORGAN INTERMEDIATES DYES
8 36464 RHEOCRICOTOPUS//O REACTIV SYNTH ORGAN//1 4 DIHALOBUTENE
9 37237 PYRAZOLE BIPYRIDINE LIGANDS//CENT S SHINAGAWA KU//1 3 BENZOXAZINONES
10 18080 CRYPTOLEPINE//CRYPTOLEPIS SANGUINOLENTA//INDOLOQUINOLINE

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