Class information for:
Level 1: SRC//SRC INHIBITORS//SARACATINIB

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10711 1040 46.8 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
373 3       ENDOGENOUS RETROVIRUS//VIROLOGY//JOURNAL OF VIROLOGY 32972
2228 2             C MYB//B MYB//SRC 4790
10711 1                   SRC//SRC INHIBITORS//SARACATINIB 1040

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SRC authKW 536455 17% 11% 174
2 SRC INHIBITORS authKW 470485 2% 64% 25
3 SARACATINIB authKW 331195 2% 59% 19
4 AZD0530 authKW 281845 1% 80% 12
5 C SRC authKW 271913 6% 14% 65
6 SRC KINASE INHIBITORS authKW 264228 1% 75% 12
7 DASATINIB authKW 243572 7% 11% 73
8 SRC KINASE authKW 161266 4% 13% 42
9 SRC FAMILY KINASES authKW 152724 4% 13% 41
10 SU6656 authKW 134207 1% 57% 8

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 8414 47% 0% 485
2 Chemistry, Medicinal 1744 13% 0% 132
3 Cell Biology 1599 21% 0% 222
4 Biochemistry & Molecular Biology 569 23% 0% 238
5 Chemistry, Organic 201 8% 0% 82
6 Pharmacology & Pharmacy 143 9% 0% 98
7 Genetics & Heredity 118 6% 0% 61
8 Biophysics 71 4% 0% 43
9 Pathology 32 2% 0% 24
10 Medicine, Research & Experimental 20 3% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHEM SCI ONCOL 117437 0% 100% 4
2 INFLAMMAT ASSOCIATED CARCINOGENESIS 58719 0% 100% 2
3 THER EUT AREA ARTHRIT BONE METAB 58719 0% 100% 2
4 ARTHRIT BONE METAB THER EUT AREA 33026 0% 38% 3
5 ABORAT INNOVAT CANC MED GYNECOL 29359 0% 100% 1
6 ANN ARBHOR S 29359 0% 100% 1
7 ASOCIAC ESPANOLA CANC AECC UNIT 29359 0% 100% 1
8 BAS PL BIOL 29359 0% 100% 1
9 BEASTON W SCOTLAND CANC CLIN 29359 0% 100% 1
10 BEHT ISRAEL DEACONESS MED 29359 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR CANCER THERAPEUTICS 5225 3% 1% 27
2 CLINICAL CANCER RESEARCH 3274 4% 0% 41
3 ONCOGENE 2548 4% 0% 40
4 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 1998 4% 0% 42
5 INVESTIGATIONAL NEW DRUGS 1636 1% 0% 12
6 CANCER RESEARCH 1330 4% 0% 43
7 MOLECULAR CARCINOGENESIS 1042 1% 0% 10
8 ONCOTARGET 833 2% 0% 19
9 MOLECULAR CANCER RESEARCH 758 1% 0% 7
10 JOURNAL OF MEDICINAL CHEMISTRY 686 2% 0% 23

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SRC 536455 17% 11% 174 Search SRC Search SRC
2 SRC INHIBITORS 470485 2% 64% 25 Search SRC+INHIBITORS Search SRC+INHIBITORS
3 SARACATINIB 331195 2% 59% 19 Search SARACATINIB Search SARACATINIB
4 AZD0530 281845 1% 80% 12 Search AZD0530 Search AZD0530
5 C SRC 271913 6% 14% 65 Search C+SRC Search C+SRC
6 SRC KINASE INHIBITORS 264228 1% 75% 12 Search SRC+KINASE+INHIBITORS Search SRC+KINASE+INHIBITORS
7 DASATINIB 243572 7% 11% 73 Search DASATINIB Search DASATINIB
8 SRC KINASE 161266 4% 13% 42 Search SRC+KINASE Search SRC+KINASE
9 SRC FAMILY KINASES 152724 4% 13% 41 Search SRC+FAMILY+KINASES Search SRC+FAMILY+KINASES
10 SU6656 134207 1% 57% 8 Search SU6656 Search SU6656

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GARGALIONIS, AN , KARAMOUZIS, MV , PAPAVASSILIOU, AG , (2014) THE MOLECULAR RATIONALE OF SRC INHIBITION IN COLORECTAL CARCINOMAS.INTERNATIONAL JOURNAL OF CANCER. VOL. 134. ISSUE 9. P. 2019 -2029 65 71% 8
2 ALESHIN, A , FINN, RS , (2010) SRC: A CENTURY OF SCIENCE BROUGHT TO THE CLINIC.NEOPLASIA. VOL. 12. ISSUE 8. P. 599 -607 47 64% 116
3 JOHNSON, FM , GALLICK, GE , (2007) SRC FAMILY NONRECEPTOR TYROSINE KINASES AS MOLECULAR TARGETS FOR CANCER THERAPY.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 7. ISSUE 6. P. 651 -659 76 51% 42
4 SUMMY, JM , GALLICK, GE , (2003) SRC FAMILY KINASES IN TUMOR PROGRESSION AND METASTASIS.CANCER AND METASTASIS REVIEWS. VOL. 22. ISSUE 4. P. 337-358 67 41% 508
5 PULS, LN , EADENS, M , MESSERSMITH, W , (2011) CURRENT STATUS OF SRC INHIBITORS IN SOLID TUMOR MALIGNANCIES.ONCOLOGIST. VOL. 16. ISSUE 5. P. 566 -578 46 65% 53
6 CHATZIZACHARIAS, NA , KOURAKLIS, GP , GIAGINIS, CT , THEOCHARIS, SE , (2012) CLINICAL SIGNIFICANCE OF SRC EXPRESSION AND ACTIVITY IN HUMAN NEOPLASIA.HISTOLOGY AND HISTOPATHOLOGY. VOL. 27. ISSUE 6. P. 677 -692 64 50% 10
7 KARIM, SA , CREEDON, H , PATEL, H , CARRAGHER, NO , MORTON, JP , MULLER, WJ , EVANS, TRJ , GUSTERSON, B , SANSOM, OJ , BRUNTON, VG , (2013) DASATINIB INHIBITS MAMMARY TUMOUR DEVELOPMENT IN A GENETICALLY ENGINEERED MOUSE MODEL.JOURNAL OF PATHOLOGY. VOL. 230. ISSUE 4. P. 430-440 44 68% 6
8 SIEMANN, DW , DONG, MY , PAMPO, C , SHI, WY , (2012) SRC-SIGNALING INTERFERENCE IMPAIRS THE DISSEMINATION OF BLOOD-BORNE TUMOR CELLS.CELL AND TISSUE RESEARCH. VOL. 349. ISSUE 2. P. 541-550 42 72% 0
9 ELSBERGER, B , (2014) TRANSLATIONAL EVIDENCE ON THE ROLE OF SRC KINASE AND ACTIVATED SRC KINASE IN INVASIVE BREAST CANCER.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 89. ISSUE 3. P. 343-351 32 80% 11
10 LIEU, C , KOPETZ, S , (2010) THE SRC FAMILY OF PROTEIN TYROSINE KINASES: A NEW AND PROMISING TARGET FOR COLORECTAL CANCER THERAPY.CLINICAL COLORECTAL CANCER. VOL. 9. ISSUE 2. P. 89-94 41 68% 21

Classes with closest relation at Level 1


Rank Class id link
1 3485 CSK//CSK HOMOLOGOUS KINASE//HEMATOL MED ENZYMOL
2 34709 CDCP1//CUB DOMAIN CONTAINING PROTEIN 1//TRASK
3 2891 FOCAL ADHESION KINASE//FAK//PAXILLIN
4 30546 NUCLEAR EGFR//EGFR FAMILY RECEPTORS//P TYR
5 11421 ANILINOQUINAZOLINE//4 ANILINOQUINAZOLINE//VEGFR 2 INHIBITOR
6 12290 SH3 DOMAIN//SH2 DOMAIN//GRB2
7 13975 PODOSOME//INVADOPODIA//CORTACTIN
8 35514 AG 1295//BONE CANC SMYELOMA//CAREGGI UNIV HOSP INTERNAL MEDAOU CAREGGI
9 25796 ANOIKIS//MED ENGN AFEKA//BIOL CELLULAIRE EXPT
10 260 CHRONIC MYELOID LEUKEMIA//IMATINIB//NILOTINIB

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