Class information for:
Level 1: FOCAL ADHESION KINASE//FAK//PAXILLIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2891 2120 50.7 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
307 3       INTEGRIN//ALPORT SYNDROME//LAMININ 40384
683 2             INTEGRIN//FOCAL ADHESION KINASE//TENASCIN C 13145
2891 1                   FOCAL ADHESION KINASE//FAK//PAXILLIN 2120

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FOCAL ADHESION KINASE authKW 2147133 18% 40% 373
2 FAK authKW 1505244 14% 36% 291
3 PAXILLIN authKW 590887 6% 31% 133
4 PYK2 authKW 545037 4% 46% 83
5 HIC 5 authKW 250014 1% 69% 25
6 FOCAL ADHESION KINASE FAK authKW 219542 2% 42% 36
7 FRNK authKW 130923 0% 91% 10
8 FAK INHIBITORS authKW 88209 0% 88% 7
9 FAK RELATED NON KINASE authKW 88209 0% 88% 7
10 FOCAL ADHESION authKW 84257 4% 7% 80

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 11553 38% 0% 808
2 Biochemistry & Molecular Biology 3969 38% 0% 798
3 Oncology 3182 21% 0% 455
4 Biophysics 456 6% 0% 135
5 Physiology 197 4% 0% 92
6 Hematology 108 3% 0% 64
7 Peripheral Vascular Diseases 99 3% 0% 59
8 Pathology 98 3% 0% 56
9 Developmental Biology 98 2% 0% 37
10 Medicine, Research & Experimental 92 4% 0% 78

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC BIOL S 49774 1% 31% 11
2 VASC ADHES 32915 0% 57% 4
3 HARVARD MED EXPT MED 32402 0% 75% 3
4 QCB 32402 0% 75% 3
5 DAVID GEFFEN MEDCUREDIGEST DIS 28803 0% 100% 2
6 IMM26 28803 0% 100% 2
7 SIGNAL TRANSDUCT IMMUNOL 28803 0% 100% 2
8 TUMOUR BIOLADHES ANGIOGENESIS 28803 0% 100% 2
9 COMPREHENS INFLAMMATORY DISORDERS 26654 0% 19% 10
10 EXPT MED HEMATOL ONCOL 23038 0% 40% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY 8411 1% 2% 25
2 JOURNAL OF BIOLOGICAL CHEMISTRY 5410 12% 0% 244
3 JOURNAL OF CELL SCIENCE 4292 3% 0% 63
4 JOURNAL OF CELL BIOLOGY 3611 3% 0% 64
5 MOLECULAR BIOLOGY OF THE CELL 2569 2% 0% 39
6 CELL ADHESION AND COMMUNICATION 1887 0% 2% 6
7 CELLULAR SIGNALLING 1563 1% 1% 22
8 ONCOGENE 1338 2% 0% 42
9 MOLECULAR AND CELLULAR BIOLOGY 1295 2% 0% 46
10 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1239 1% 0% 20

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FOCAL ADHESION KINASE 2147133 18% 40% 373 Search FOCAL+ADHESION+KINASE Search FOCAL+ADHESION+KINASE
2 FAK 1505244 14% 36% 291 Search FAK Search FAK
3 PAXILLIN 590887 6% 31% 133 Search PAXILLIN Search PAXILLIN
4 PYK2 545037 4% 46% 83 Search PYK2 Search PYK2
5 HIC 5 250014 1% 69% 25 Search HIC+5 Search HIC+5
6 FOCAL ADHESION KINASE FAK 219542 2% 42% 36 Search FOCAL+ADHESION+KINASE+FAK Search FOCAL+ADHESION+KINASE+FAK
7 FRNK 130923 0% 91% 10 Search FRNK Search FRNK
8 FAK INHIBITORS 88209 0% 88% 7 Search FAK+INHIBITORS Search FAK+INHIBITORS
9 FAK RELATED NON KINASE 88209 0% 88% 7 Search FAK+RELATED+NON+KINASE Search FAK+RELATED+NON+KINASE
10 FOCAL ADHESION 84257 4% 7% 80 Search FOCAL+ADHESION Search FOCAL+ADHESION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LEE, BY , TIMPSON, P , HORVATH, LG , DALY, RJ , (2015) FAK SIGNALING IN HUMAN CANCER AS A TARGET FOR THERAPEUTICS.PHARMACOLOGY & THERAPEUTICS. VOL. 146. ISSUE . P. 132 -149 192 72% 20
2 SULZMAIER, FJ , JEAN, C , SCHLAEPFER, DD , (2014) FAK IN CANCER: MECHANISTIC FINDINGS AND CLINICAL APPLICATIONS.NATURE REVIEWS CANCER. VOL. 14. ISSUE 9. P. 598 -610 96 74% 126
3 ZHAO, J , GUAN, JL , (2009) SIGNAL TRANSDUCTION BY FOCAL ADHESION KINASE IN CANCER.CANCER AND METASTASIS REVIEWS. VOL. 28. ISSUE 1-2. P. 35 -49 120 73% 264
4 GOLUBOVSKAYA, VM , (2014) TARGETING FAK IN HUMAN CANCER: FROM FINDING TO FIRST CLINICAL TRIALS.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 19. ISSUE . P. 687 -706 120 83% 26
5 SCHLAEPFER, DD , HAUCK, CR , SIEG, DJ , (1999) SIGNALING THROUGH FOCAL ADHESION KINASE.PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY. VOL. 71. ISSUE 3-4. P. 435 -478 143 58% 830
6 HALL, JE , FU, W , SCHALLER, MD , (2011) FOCAL ADHESION KINASE: EXPLORING FAK STRUCTURE TO GAIN INSIGHT INTO FUNCTION.INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 288. VOL. 288. ISSUE . P. 185 -225 120 76% 47
7 GOLUBOVSKAYA, VM , CANCE, WG , (2007) FOCAL ADHESION KINASE AND P53 SIGNALING IN CANCER CELLS.INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 263. VOL. 263. ISSUE . P. 103-+ 154 63% 45
8 LUO, M , GUAN, JL , (2010) FOCAL ADHESION KINASE: A PROMINENT DETERMINANT IN BREAST CANCER INITIATION, PROGRESSION AND METASTASIS.CANCER LETTERS. VOL. 289. ISSUE 2. P. 127-139 110 65% 98
9 YOON, H , DEHART, JP , MURPHY, JM , LIM, STS , (2015) UNDERSTANDING THE ROLES OF FAK IN CANCER: INHIBITORS, GENETIC MODELS, AND NEW INSIGHTS.JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. VOL. 63. ISSUE 2. P. 114 -128 90 80% 6
10 PENG, X , GUAN, JL , (2011) FOCAL ADHESION KINASE: FROM IN VITRO STUDIES TO FUNCTIONAL ANALYSES IN VIVO.CURRENT PROTEIN & PEPTIDE SCIENCE. VOL. 12. ISSUE 1. P. 52 -67 115 69% 15

Classes with closest relation at Level 1


Rank Class id link
1 25796 ANOIKIS//MED ENGN AFEKA//BIOL CELLULAIRE EXPT
2 13570 NEDD9//CRK//CRKL
3 28130 SCHLAFEN//SURG SERV 11S//DDK SYNDROME
4 16429 INTEGRIN LINKED KINASE//ILK//INTEGRIN LINKED KINASE ILK
5 10711 SRC//SRC INHIBITORS//SARACATINIB
6 2335 INTEGRIN//INTEGRIN ALPHA 6 BETA 4//VLA 1
7 16892 GENISTEIN INHIBITION//TYROSINE KINASE//ANGIOTENSIN II
8 14689 VINCULIN//VINEXIN//ALPHA ACTININ
9 25952 CAM DR//CELL ADHESION MEDIATED DRUG RESISTANCE//RECEPTOR BIOL TUMOR METASTASIS
10 35261 CKAP2//DERIVATIZED BEADS//FATTY ACID CYTOTOXICITY

Go to start page