Class information for:
Level 1: CYCLOOXYGENASE//NEUROINFLAMMAT S//BUTAPROST

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10681 1042 52.9 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
385 3       MICROGLIA//MAGNETIC RESONANCE SPECTROSCOPY//LITHIUM 31368
903 2             MICROGLIA//BRAIN BEHAVIOR AND IMMUNITY//CYTOKINES 11265
10681 1                   CYCLOOXYGENASE//NEUROINFLAMMAT S//BUTAPROST 1042

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYCLOOXYGENASE authKW 140320 12% 4% 129
2 NEUROINFLAMMAT S address 137545 1% 36% 13
3 BUTAPROST authKW 68364 1% 33% 7
4 CYCLOOXYGENASE 2 authKW 66486 9% 3% 89
5 BUDESONIDE EPIMER R authKW 58606 0% 100% 2
6 C 11KETOPROFEN METHYL ESTER authKW 58606 0% 100% 2
7 CYCLOOXGENASES authKW 58606 0% 100% 2
8 EP2 authKW 57783 1% 16% 12
9 MOL NEUROSCI UNIT address 53570 1% 23% 8
10 PROSTAGLANDINS authKW 50879 11% 2% 114

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 9071 54% 0% 562
2 Clinical Neurology 1544 18% 0% 186
3 Geriatrics & Gerontology 1340 6% 0% 66
4 Pharmacology & Pharmacy 669 17% 0% 176
5 Biochemistry & Molecular Biology 127 14% 0% 143
6 Pathology 114 4% 0% 38
7 Gerontology 73 1% 0% 13
8 Immunology 50 5% 0% 55
9 Psychiatry 50 4% 0% 38
10 Medicine, Research & Experimental 28 3% 0% 33

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROINFLAMMAT S 137545 1% 36% 13
2 MOL NEUROSCI UNIT 53570 1% 23% 8
3 BRAIN PHYSIOL METAB SECT 45958 2% 8% 19
4 CIEB IFAL 39069 0% 67% 2
5 TRANSLAT MED OPHTHALMOL 39069 0% 67% 2
6 ACRAF SPA ANGELINI 29303 0% 100% 1
7 AMGEN SOUTH SAN FRANCISCO 29303 0% 100% 1
8 BIOMED BARCELONA INVEST BIOMED AUGU 29303 0% 100% 1
9 BRAIN I EMIA NEURODEGENERATCSIC 29303 0% 100% 1
10 CLIN NEUROSCICLIN EXPT SCI UNIT 29303 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NEUROINFLAMMATION 6289 2% 1% 19
2 NEUROBIOLOGY OF AGING 2660 2% 0% 23
3 ALZHEIMERS & DEMENTIA 2206 1% 1% 8
4 NEUROBIOLOGY OF DISEASE 2024 2% 0% 16
5 JOURNAL OF NEUROCHEMISTRY 1979 4% 0% 38
6 JOURNAL OF NEUROIMMUNOLOGY 1542 2% 0% 19
7 JOURNAL OF ALZHEIMERS DISEASE 1433 1% 0% 15
8 BRAIN RESEARCH 1418 5% 0% 49
9 JOURNAL OF NEUROSCIENCE RESEARCH 1306 2% 0% 20
10 NEUROCHEMISTRY INTERNATIONAL 1214 1% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CYCLOOXYGENASE 140320 12% 4% 129 Search CYCLOOXYGENASE Search CYCLOOXYGENASE
2 BUTAPROST 68364 1% 33% 7 Search BUTAPROST Search BUTAPROST
3 CYCLOOXYGENASE 2 66486 9% 3% 89 Search CYCLOOXYGENASE+2 Search CYCLOOXYGENASE+2
4 BUDESONIDE EPIMER R 58606 0% 100% 2 Search BUDESONIDE+EPIMER+R Search BUDESONIDE+EPIMER+R
5 C 11KETOPROFEN METHYL ESTER 58606 0% 100% 2 Search C+11KETOPROFEN+METHYL+ESTER Search C+11KETOPROFEN+METHYL+ESTER
6 CYCLOOXGENASES 58606 0% 100% 2 Search CYCLOOXGENASES Search CYCLOOXGENASES
7 EP2 57783 1% 16% 12 Search EP2 Search EP2
8 PROSTAGLANDINS 50879 11% 2% 114 Search PROSTAGLANDINS Search PROSTAGLANDINS
9 NEUROINFLAMMATION 48172 8% 2% 81 Search NEUROINFLAMMATION Search NEUROINFLAMMATION
10 ANIMAL MODEL OF ALZHEIMERS DISEASE 39069 0% 67% 2 Search ANIMAL+MODEL+OF+ALZHEIMERS+DISEASE Search ANIMAL+MODEL+OF+ALZHEIMERS+DISEASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CANDELARIO-JALIL, E , FIEBICH, BL , (2008) CYCLOOXYGENASE INHIBITION IN ISCHEMIC BRAIN INJURY.CURRENT PHARMACEUTICAL DESIGN. VOL. 14. ISSUE 14. P. 1401-1418 136 47% 49
2 MCGEER, PL , MCGEER, EG , (2007) NSAIDS AND ALZHEIMER DISEASE: EPIDEMIOLOGICAL, ANIMAL MODEL AND CLINICAL STUDIES.NEUROBIOLOGY OF AGING. VOL. 28. ISSUE 5. P. 639-647 45 69% 259
3 CUDABACK, E , JORSTAD, NL , YANG, Y , MONTINE, TJ , KEENE, CD , (2014) THERAPEUTIC IMPLICATIONS OF THE PROSTAGLANDIN PATHWAY IN ALZHEIMER'S DISEASE.BIOCHEMICAL PHARMACOLOGY. VOL. 88. ISSUE 4. P. 565-572 56 48% 20
4 ROJAS, A , JIANG, JX , GANESH, T , YANG, MS , LELUTIU, N , GUEORGUIEVA, P , DINGLEDINE, R , (2014) CYCLOOXYGENASE-2 IN EPILEPSY.EPILEPSIA. VOL. 55. ISSUE 1. P. 17-25 41 59% 26
5 IMBIMBO, BP , (2009) AN UPDATE ON THE EFFICACY OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS IN ALZHEIMER'S DISEASE.EXPERT OPINION ON INVESTIGATIONAL DRUGS. VOL. 18. ISSUE 8. P. 1147-1168 52 51% 49
6 WOODLING, NS , ANDREASSON, KI , (2016) UNTANGLING THE WEB: TOXIC AND PROTECTIVE EFFECTS OF NEUROINFLAMMATION AND PGE(2) SIGNALING IN ALZHEIMER'S DISEASE.ACS CHEMICAL NEUROSCIENCE. VOL. 7. ISSUE 4. P. 454 -463 45 49% 2
7 HOOZEMANS, JJM , ROZEMULLER, JM , VAN HAASTERT, ES , VEERHUIS, R , EIKELENBOOM, P , (2008) CYCLOOXYGENASE-1 AND-2 IN THE DIFFERENT STAGES OF ALZHEIMER'S DISEASE PATHOLOGY.CURRENT PHARMACEUTICAL DESIGN. VOL. 14. ISSUE 14. P. 1419-1427 52 50% 67
8 HOOZEMANS, JJM , VEERHUIS, R , ROZEMULLER, JM , EIKELENBOOM, P , (2011) SOOTHING THE INFLAMED BRAIN: EFFECT OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ON ALZHEIMER'S DISEASE PATHOLOGY.CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. VOL. 10. ISSUE 1. P. 57-67 55 47% 21
9 CHAUDHRY, U , ZHUANG, H , DORE, S , (2010) MICROSOMAL PROSTAGLANDIN E SYNTHASE-2: CELLULAR DISTRIBUTION AND EXPRESSION IN ALZHEIMER'S DISEASE.EXPERIMENTAL NEUROLOGY. VOL. 223. ISSUE 2. P. 359-365 37 74% 13
10 GROSSBERG, GT , DEARDORFF, WJ , (2017) TARGETING NEUROINFLAMMATION IN ALZHEIMER'S DISEASE: EVIDENCE FOR NSAIDS AND NOVEL THERAPEUTICS.EXPERT REVIEW OF NEUROTHERAPEUTICS. VOL. 17. ISSUE 1. P. 17 -32 41 36% 1

Classes with closest relation at Level 1


Rank Class id link
1 13268 INTERLEUKIN 6//ALZHEIMERS DISEASE//IL 6 MESSENGER RNA
2 16201 COMPLEMENT//BIIG//VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN
3 13000 ARACHIDONIC ACID//LEUKOTRIENE C 4 SYNTHESIS DEFICIENCY//5 8 1 14 EICOSATETRAYNOIC ACID
4 19756 MPGES 1//PROSTAGLANDIN E SYNTHASE//MPGES 1 INHIBITORS
5 22293 INTEGRAT IMMUNOL BEHAV//ANIM SCI 4//ESCAPE AVOIDANCE CONDITIONING
6 5984 PROSTANOID RECEPTORS//EP3 RECEPTOR//IP RECEPTOR
7 2243 CYCLOOXYGENASE//PROSTAGLANDIN H SYNTHASE//AB HANCOCK JR MEM CANC
8 8954 NEUROPHARMACOL SECT//MICROGLIA//PARKINSONS DISEASE
9 13564 EPILEPTOGENESIS//NEURO PATHOL//EMERGENCY ACUTA
10 3379 ALZHEIMERS DISEASE//BAPINEUZUMAB//AMYLOID BETA

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