Class information for:
Level 1: INTERLEUKIN 6//ALZHEIMERS DISEASE//IL 6 MESSENGER RNA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13268 850 49.8 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
385 3       MICROGLIA//MAGNETIC RESONANCE SPECTROSCOPY//LITHIUM 31368
903 2             MICROGLIA//BRAIN BEHAVIOR AND IMMUNITY//CYTOKINES 11265
13268 1                   INTERLEUKIN 6//ALZHEIMERS DISEASE//IL 6 MESSENGER RNA 850

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERLEUKIN 6 authKW 89157 17% 2% 142
2 ALZHEIMERS DISEASE authKW 87002 38% 1% 322
3 IL 6 MESSENGER RNA authKW 80824 0% 75% 3
4 PRIMITIVE PLAQUES authKW 80824 0% 75% 3
5 CAS 2149 70 4 authKW 71845 0% 100% 2
6 DENDROBIUM NOBILE LINDL ALKALOIDS authKW 71845 0% 100% 2
7 EUROPEAN QUAL LIFE address 71845 0% 100% 2
8 LIFE SCI CAIR address 71845 0% 100% 2
9 PERIPHERAL BLOOD MONO NUCLEAR CELL PBMC authKW 71845 0% 100% 2
10 PERIPHERAL CYTOKINE RELEASE authKW 71845 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Geriatrics & Gerontology 9247 18% 0% 152
2 Neurosciences 7419 54% 0% 459
3 Clinical Neurology 1833 21% 0% 180
4 Gerontology 796 4% 0% 35
5 Psychiatry 549 10% 0% 86
6 Immunology 370 12% 0% 99
7 Pathology 93 4% 0% 31
8 Integrative & Complementary Medicine 37 1% 0% 8
9 Pharmacology & Pharmacy 32 6% 0% 54
10 Medicine, Research & Experimental 23 3% 0% 27

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN QUAL LIFE 71845 0% 100% 2
2 LIFE SCI CAIR 71845 0% 100% 2
3 ST VINCENT AGING 71845 0% 100% 2
4 AGING ANTIAGING COGNIT FUNCT 35923 0% 100% 1
5 ALZHEIMER EVALUAT UNITIDR S MARGHERITA 35923 0% 100% 1
6 ASSOC FRATEBENEFRATELLI RIC 35923 0% 100% 1
7 BECTON HLTH 35923 0% 100% 1
8 BIOL CELLULAR MOL BIOL NEUROSCI 35923 0% 100% 1
9 BRAIN AGING NEUROPATHOL CORE PATIENT SUMMARY 35923 0% 100% 1
10 CANTONAL PUBL 35923 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROBIOLOGY OF AGING 11509 5% 1% 43
2 DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 7640 2% 1% 20
3 JOURNAL OF ALZHEIMERS DISEASE 5757 3% 1% 27
4 JOURNAL OF NEUROINFLAMMATION 5468 2% 1% 16
5 JOURNAL OF NEUROIMMUNOLOGY 5428 4% 0% 32
6 CURRENT ALZHEIMER RESEARCH 4578 1% 1% 11
7 NEUROSCIENCE LETTERS 4244 7% 0% 61
8 AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS 2621 1% 1% 7
9 EXPERIMENTAL GERONTOLOGY 2144 2% 0% 15
10 NEURODEGENERATIVE DISEASES 1295 1% 1% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INTERLEUKIN 6 89157 17% 2% 142 Search INTERLEUKIN+6 Search INTERLEUKIN+6
2 ALZHEIMERS DISEASE 87002 38% 1% 322 Search ALZHEIMERS+DISEASE Search ALZHEIMERS+DISEASE
3 IL 6 MESSENGER RNA 80824 0% 75% 3 Search IL+6+MESSENGER+RNA Search IL+6+MESSENGER+RNA
4 PRIMITIVE PLAQUES 80824 0% 75% 3 Search PRIMITIVE+PLAQUES Search PRIMITIVE+PLAQUES
5 CAS 2149 70 4 71845 0% 100% 2 Search CAS+2149+70+4 Search CAS+2149+70+4
6 DENDROBIUM NOBILE LINDL ALKALOIDS 71845 0% 100% 2 Search DENDROBIUM+NOBILE+LINDL+ALKALOIDS Search DENDROBIUM+NOBILE+LINDL+ALKALOIDS
7 PERIPHERAL BLOOD MONO NUCLEAR CELL PBMC 71845 0% 100% 2 Search PERIPHERAL+BLOOD+MONO+NUCLEAR+CELL+PBMC Search PERIPHERAL+BLOOD+MONO+NUCLEAR+CELL+PBMC
8 PERIPHERAL CYTOKINE RELEASE 71845 0% 100% 2 Search PERIPHERAL+CYTOKINE+RELEASE Search PERIPHERAL+CYTOKINE+RELEASE
9 PERIPHERAL INFLAMMATORY MARKERS 71845 0% 100% 2 Search PERIPHERAL+INFLAMMATORY+MARKERS Search PERIPHERAL+INFLAMMATORY+MARKERS
10 INTERLEUKIN 1A 64141 1% 36% 5 Search INTERLEUKIN+1A Search INTERLEUKIN+1A

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BROSSERON, F , KRAUTHAUSEN, M , KUMMER, M , HENEKA, MT , (2014) BODY FLUID CYTOKINE LEVELS IN MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE: A COMPARATIVE OVERVIEW.MOLECULAR NEUROBIOLOGY. VOL. 50. ISSUE 2. P. 534 -544 64 49% 30
2 SU, F , BAI, F , ZHANG, ZJ , (2016) INFLAMMATORY CYTOKINES AND ALZHEIMER'S DISEASE: A REVIEW FROM THE PERSPECTIVE OF GENETIC POLYMORPHISMS.NEUROSCIENCE BULLETIN. VOL. 32. ISSUE 5. P. 469 -480 67 49% 1
3 SWARDFAGER, W , LANCTOT, K , ROTHENBURG, L , WONG, A , CAPPELL, J , HERRMANN, N , (2010) A META-ANALYSIS OF CYTOKINES IN ALZHEIMER'S DISEASE.BIOLOGICAL PSYCHIATRY. VOL. 68. ISSUE 10. P. 930 -941 66 35% 210
4 SPOOREN, A , KOLMUS, K , LAUREYS, G , CLINCKERS, R , DE KEYSER, J , HAEGEMAN, G , GERLO, S , (2011) INTERLEUKIN-6, A MENTAL CYTOKINE.BRAIN RESEARCH REVIEWS. VOL. 67. ISSUE 1-2. P. 157 -183 88 28% 119
5 LEE, KS , CHUNG, JH , CHOI, TK , SUH, SY , OH, BH , HONG, CH , (2009) PERIPHERAL CYTOKINES AND CHEMOKINES IN ALZHEIMER'S DISEASE.DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. VOL. 28. ISSUE 4. P. 281-287 33 73% 57
6 WEISMAN, D , HAKIMIAN, E , HO, GJ , (2006) INTERLEUKINS, INFLAMMATION, AND MECHANISMS OF ALZHEIMER'S DISEASE.INTERLEUKINS. VOL. 74. ISSUE . P. 505-530 58 48% 47
7 DONG, XL , ZHANG, L , MENG, QL , GAO, QY , (2017) ASSOCIATION BETWEEN INTERLEUKIN-1A, INTERLEUKIN-1B, AND BRIDGING INTEGRATOR 1 POLYMORPHISMS AND ALZHEIMER'S DISEASE: A STANDARD AND CUMULATIVE META-ANALYSIS.MOLECULAR NEUROBIOLOGY. VOL. 54. ISSUE 1. P. 736 -747 39 55% 0
8 HUA, Y , GUO, XD , HUANG, Q , KONG, YN , LU, XJ , (2013) ASSOCIATION BETWEEN INTERLEUKIN-6-174G/C POLYMORPHISM AND THE RISK OF ALZHEIMER'S DISEASE: A META-ANALYSIS.INTERNATIONAL JOURNAL OF NEUROSCIENCE. VOL. 123. ISSUE 9. P. 626 -635 30 75% 6
9 ERTA, M , QUINTANA, A , HIDALGO, J , (2012) INTERLEUKIN-6, A MAJOR CYTOKINE IN THE CENTRAL NERVOUS SYSTEM.INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES. VOL. 8. ISSUE 9. P. 1254-1266 59 25% 155
10 GRUOL, DL , (2015) IL-6 REGULATION OF SYNAPTIC FUNCTION IN THE CNS.NEUROPHARMACOLOGY. VOL. 96. ISSUE . P. 42 -54 52 32% 11

Classes with closest relation at Level 1


Rank Class id link
1 22032 ALPHA 1 ANTICHYMOTRYPSIN//ALPHA1 ANTICHYMOTRYPSIN POLYMORPHISM//SERUM ALPHA1 ANTICHYMOTRYPSIN
2 22293 INTEGRAT IMMUNOL BEHAV//ANIM SCI 4//ESCAPE AVOIDANCE CONDITIONING
3 10681 CYCLOOXYGENASE//NEUROINFLAMMAT S//BUTAPROST
4 16201 COMPLEMENT//BIIG//VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN
5 3379 ALZHEIMERS DISEASE//BAPINEUZUMAB//AMYLOID BETA
6 21373 BXSB MOUSE//BIOBEHAV SCI DEGREE PROGRAM//LASHLEY MAZE
7 26906 INT ALZHEIMER//HERPES SIMPLEX TYPE 1 VIRUS//HERPES SIMPLEX VIRUS TYPE 1 HSV1
8 21816 GFAP GENE PROMOTER//TGF BETA 1 TRANSGENIC MICE//PHENOTYPE INDUCTION
9 8954 NEUROPHARMACOL SECT//MICROGLIA//PARKINSONS DISEASE
10 14960 CHEMOKINES//CHEMOKINE RECEPTOR//EXPT CLIN NEUROL

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