Class information for: |
Basic class information |
| Class id | #P | Avg. number of references |
Database coverage of references |
|---|---|---|---|
| 3679 | 1142 | 23.4 | 35% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
Terms with highest relevance score |
| rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
|---|---|---|---|---|---|---|
| 1 | ADRENERGIC DRUG | authKW | 163762 | 1% | 88% | 7 |
| 2 | FARMACO-EDIZIONE SCIENTIFICA | journal | 74218 | 4% | 6% | 48 |
| 3 | 1 2 4TRIAZOLO1 5 AQUINOLINES | authKW | 53474 | 0% | 100% | 2 |
| 4 | 2 5ISOXAZOLIDINYL ETHANOLAMINES | authKW | 53474 | 0% | 100% | 2 |
| 5 | BIOPHYS CYTOCHEM | address | 53474 | 0% | 100% | 2 |
| 6 | ETHANOL DIESEL FUEL ADDITIVE BLENDS | authKW | 53474 | 0% | 100% | 2 |
| 7 | ISOCHROMAN 4 ONE DERIVATIVES | authKW | 53474 | 0% | 100% | 2 |
| 8 | L RHAMNOPYRANOSYL BROMIDE | authKW | 53474 | 0% | 100% | 2 |
| 9 | LFER RELATED PARAMETERS | authKW | 53474 | 0% | 100% | 2 |
| 10 | N SUBSTITUTED AZEPINES | authKW | 53474 | 0% | 100% | 2 |
Web of Science journal categories |
| Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
|---|---|---|---|---|---|
| 1 | Chemistry, Medicinal | 7811 | 25% | 0% | 283 |
| 2 | Pharmacology & Pharmacy | 4071 | 36% | 0% | 408 |
| 3 | Chemistry, Organic | 1667 | 18% | 0% | 210 |
| 4 | Crystallography | 544 | 6% | 0% | 74 |
| 5 | Chemistry, Multidisciplinary | 332 | 14% | 0% | 157 |
| 6 | BIOLOGY, MISCELLANEOUS | 66 | 0% | 0% | 2 |
| 7 | MEDICINE, MISCELLANEOUS | 64 | 0% | 0% | 2 |
| 8 | Biophysics | 18 | 3% | 0% | 30 |
| 9 | Toxicology | 13 | 2% | 0% | 21 |
| 10 | Neurosciences | 5 | 4% | 0% | 47 |
Address terms |
| Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
|---|---|---|---|---|---|
| 1 | BIOPHYS CYTOCHEM | 53474 | 0% | 100% | 2 |
| 2 | CENT 21785 JUSOHONMACHI YODOGAWA KU | 26737 | 0% | 100% | 1 |
| 3 | CHIM ORGANUFR PHARM | 26737 | 0% | 100% | 1 |
| 4 | CHINA STATE NEW DRUG PHARMACEUT PROC | 26737 | 0% | 100% | 1 |
| 5 | DEV SPECIAL FUNCT PL GENOM | 26737 | 0% | 100% | 1 |
| 6 | DIPARTIMENTO PSICHIAT NEURBIOL FARMACOL BIOTECN | 26737 | 0% | 100% | 1 |
| 7 | EAD PHYS CHIM IND MEDICAMENT | 26737 | 0% | 100% | 1 |
| 8 | EUCRO | 26737 | 0% | 100% | 1 |
| 9 | FU14 | 26737 | 0% | 100% | 1 |
| 10 | GRUPPE INNERE MED | 26737 | 0% | 100% | 1 |
Journals |
| Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
|---|---|---|---|---|---|
| 1 | FARMACO-EDIZIONE SCIENTIFICA | 74218 | 4% | 6% | 48 |
| 2 | FARMACO | 51343 | 5% | 3% | 58 |
| 3 | JOURNAL OF MEDICINAL CHEMISTRY | 13675 | 9% | 0% | 105 |
| 4 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 8316 | 5% | 1% | 54 |
| 5 | ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH | 2402 | 2% | 0% | 20 |
| 6 | JOURNAL OF PHARMACOBIO-DYNAMICS | 2343 | 1% | 1% | 12 |
| 7 | ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA | 2040 | 1% | 1% | 7 |
| 8 | JOURNAL OF HETEROCYCLIC CHEMISTRY | 1752 | 2% | 0% | 27 |
| 9 | JOURNAL OF CRYSTALLOGRAPHIC AND SPECTROSCOPIC RESEARCH | 1699 | 1% | 1% | 8 |
| 10 | RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY | 1662 | 1% | 1% | 12 |
Author Key Words |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
| Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
|---|---|---|---|---|
| 1 | GRUNEWALD, GL , LU, J , CRISCIONE, KR , MORO, CO , (2005) INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE DEVOID OF ALPHA(2)-ADRENOCEPTOR AFFINITY.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 15. ISSUE 23. P. 5319-5323 | 19 | 90% | 23 |
| 2 | GRUNEWALD, GL , SEIM, MR , BHAT, SR , WILSON, ME , CRISCIONE, KR , (2008) SYNTHESIS OF 4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINES AND COMPARISON WITH THEIR ISOSTERIC 1,2,3,4-TETRAHYDROISOQUINOLINES AS INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 16. ISSUE 1. P. 542-559 | 24 | 63% | 11 |
| 3 | GRUNEWALD, GL , SEIM, MR , REGIER, RC , MARTIN, JL , GEE, CL , DRINKWATER, N , CRISCIONE, KR , (2006) COMPARISON OF THE BINDING OF 3-FLUOROMETHYL-7-SULFONYL-1,2,3,4-TETRAHYDROISOQUINOLINES WITH THEIR ISOSTERIC SULFONAMIDES TO THE ACTIVE SITE OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 49. ISSUE 18. P. 5424 -5433 | 22 | 67% | 20 |
| 4 | WU, Q , MCLEISH, MJ , (2013) KINETIC AND PH STUDIES ON HUMAN PHENYLETHANOLAMINE N-METHYLTRANSFERASE.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 539. ISSUE 1. P. 1 -8 | 21 | 55% | 2 |
| 5 | NAIR, PC , MALDE, AK , MARK, AE , (2011) USING THEORY TO RECONCILE EXPERIMENT: THE STRUCTURAL AND THERMODYNAMIC BASIS OF LIGAND RECOGNITION BY PHENYLETHANOLAMINE N-METHYLTRANSFERASE (PNMT).JOURNAL OF CHEMICAL THEORY AND COMPUTATION. VOL. 7. ISSUE 5. P. 1458-1468 | 19 | 63% | 5 |
| 6 | GRUNEWALD, GL , SEIM, MR , LU, J , MAKBOUL, M , CRISCIONE, KR , (2006) APPLICATION OF THE GOLDILOCKS EFFECT TO THE DESIGN OF POTENT AND SELECTIVE INHIBITORS OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE: BALANCING PK(A) AND STERIC EFFECTS IN THE OPTIMIZATION OF 3-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE INHIBITORS BY BETA-FLUORINATION.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 49. ISSUE 10. P. 2939 -2952 | 22 | 59% | 16 |
| 7 | GRUNEWALD, GL , MCLEISH, MJ , CRISCIONE, KR , (2001) PHENYLETHANOLAMINE N-METHYLTRANSFERASE KINETICS: BOVINE VERSUS RECOMBINANT HUMAN ENZYME.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 11. ISSUE 12. P. 1579-1582 | 15 | 100% | 5 |
| 8 | WU, Q , GEE, CL , LIN, F , TYNDALL, JD , MARTIN, JL , GRUNEWALD, GL , MCLEISH, MJ , (2005) STRUCTURAL, MUTAGENIC, AND KINETIC ANALYSIS OF THE BINDING OF SUBSTRATES AND INHIBITORS OF HUMAN PHENYLETHANOLAMINE N-METHYLTRANSFERASE.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 48. ISSUE 23. P. 7243-7252 | 22 | 55% | 17 |
| 9 | DRINKWATER, N , GEE, CL , PURI, M , CRISCIONE, KR , MCLEISH, MJ , GRUNEWALD, GL , MARTIN, JL , (2009) MOLECULAR RECOGNITION OF PHYSIOLOGICAL SUBSTRATE NORADRENALINE BY THE ADRENALINE-SYNTHESIZING ENZYME PNMT AND FACTORS INFLUENCING ITS METHYLTRANSFERASE ACTIVITY.BIOCHEMICAL JOURNAL. VOL. 422. ISSUE . P. 463-471 | 20 | 53% | 7 |
| 10 | BALSAMO, A , MACCHIA, M , MARTINELLI, A , ROSSELLO, A , (1999) THE [(METHYLOXY)IMINO]METHYL MOIETY (MOIMM) IN THE DESIGN OF A NEW TYPE OF BETA-ADRENERGIC BLOCKING AGENT.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 34. ISSUE 4. P. 283-291 | 16 | 89% | 3 |
Classes with closest relation at Level 2 |