Class information for:
Level 2: FLAVIN CONTAINING MONOOXYGENASE//FMO3//TRIMETHYLAMINURIA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3464 1499 31.1 57%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
3464 2             FLAVIN CONTAINING MONOOXYGENASE//FMO3//TRIMETHYLAMINURIA 1499
12548 1                   FLAVIN CONTAINING MONOOXYGENASE//FMO3//TRIMETHYLAMINURIA 897
31107 1                   DIMETHYLETHYLAMINE//DIMETHYLETHYLAMINE N OXIDE//OCCUPAT HLTH SURG 158
33327 1                   ANGLE RESOLVED MEASUREMENT//APMSF//FLOW THROUGH COLUMN 126
35640 1                   ALLOTROPIC FORM//CEQUINORCONICETCCT LA PLATA UNLP//CIENCIAS EXACTAS CEQUINOR 94
35767 1                   3 DIMENSIONAL IMAGE SPACE//3 DIMENSIONAL REAL IMAGES//BIOCHEM BIOMIMET 92
36997 1                   NICLOSAMIDE//WNT SIGNALING INHIBITOR//50 GROWTH INHIBITION VALUE 69
37248 1                   INVEST BIOMED ARTADO POSTAL 70228//ANTHELMINTIC EXPOSURE//APPLICATION FOR MARKETING AUTHORIZATION 63

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FLAVIN CONTAINING MONOOXYGENASE authKW 1575632 7% 72% 107
2 FMO3 authKW 713320 3% 85% 41
3 TRIMETHYLAMINURIA authKW 708469 3% 87% 40
4 TRIMETHYLAMINE N OXIDE authKW 424187 4% 39% 54
5 FISH ODOUR SYNDROME authKW 264794 1% 100% 13
6 FISH ODOR SYNDROME authKW 244426 1% 100% 12
7 FLAVIN CONTAINING MONOOXYGENASE 3 authKW 241203 1% 79% 15
8 NICLOSAMIDE authKW 174366 2% 25% 34
9 TRIMETHYLAMINE authKW 166264 3% 17% 49
10 FMO authKW 131365 2% 24% 27

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 4811 17% 0% 261
2 Pharmacology & Pharmacy 2627 26% 0% 389
3 Biochemistry & Molecular Biology 407 18% 0% 266
4 Chemistry, Analytical 202 6% 0% 97
5 Genetics & Heredity 193 6% 0% 92
6 Biophysics 174 5% 0% 75
7 Biochemical Research Methods 74 3% 0% 50
8 Spectroscopy 73 3% 0% 39
9 Chemistry, Medicinal 51 3% 0% 38
10 Chemistry, Inorganic & Nuclear 48 3% 0% 47

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNITE TOXICOL METAB COMPA XENOBIOT 104752 0% 86% 6
2 INVEST BIOMED ARTADO POSTAL 70228 40738 0% 100% 2
3 OCCUPAT HLTH SURG 40738 0% 100% 2
4 ST MARYS HOSP MED PHARMACOL TOXICOL 40738 0% 100% 2
5 PL TOXICOL GRP 40726 1% 25% 8
6 QUEEN SIRIKIT HEART NORTHEAST 22911 0% 38% 3
7 AFFILIATED HOSP XIANGYA 2 20369 0% 100% 1
8 AITTALUODON TERVEYSASEMA 20369 0% 100% 1
9 ANIM GENOM BIOTECHNOL FOOD 20369 0% 100% 1
10 BIOCHEM BIOMIMET 20369 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG METABOLISM AND DISPOSITION 16015 5% 1% 77
2 PHARMACOGENETICS 6196 1% 2% 17
3 XENOBIOTICA 5681 2% 1% 33
4 JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY 2735 1% 2% 8
5 BIOCHEMICAL PHARMACOLOGY 2576 3% 0% 49
6 CHEMICAL RESEARCH IN TOXICOLOGY 2217 2% 0% 24
7 DRUG METABOLISM REVIEWS 1642 1% 1% 9
8 DRUG METABOLISM AND PHARMACOKINETICS 1370 0% 1% 7
9 MOLECULAR PHARMACOLOGY 1264 2% 0% 25
10 TOXIC SUBSTANCE MECHANISMS 1097 0% 3% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FLAVIN CONTAINING MONOOXYGENASE 1575632 7% 72% 107 Search FLAVIN+CONTAINING+MONOOXYGENASE Search FLAVIN+CONTAINING+MONOOXYGENASE
2 FMO3 713320 3% 85% 41 Search FMO3 Search FMO3
3 TRIMETHYLAMINURIA 708469 3% 87% 40 Search TRIMETHYLAMINURIA Search TRIMETHYLAMINURIA
4 TRIMETHYLAMINE N OXIDE 424187 4% 39% 54 Search TRIMETHYLAMINE+N+OXIDE Search TRIMETHYLAMINE+N+OXIDE
5 FISH ODOUR SYNDROME 264794 1% 100% 13 Search FISH+ODOUR+SYNDROME Search FISH+ODOUR+SYNDROME
6 FISH ODOR SYNDROME 244426 1% 100% 12 Search FISH+ODOR+SYNDROME Search FISH+ODOR+SYNDROME
7 FLAVIN CONTAINING MONOOXYGENASE 3 241203 1% 79% 15 Search FLAVIN+CONTAINING+MONOOXYGENASE+3 Search FLAVIN+CONTAINING+MONOOXYGENASE+3
8 NICLOSAMIDE 174366 2% 25% 34 Search NICLOSAMIDE Search NICLOSAMIDE
9 TRIMETHYLAMINE 166264 3% 17% 49 Search TRIMETHYLAMINE Search TRIMETHYLAMINE
10 FMO 131365 2% 24% 27 Search FMO Search FMO

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KRUEGER, SK , WILLIAMS, DE , (2005) MAMMALIAN FLAVIN-CONTAINING MONOOXYGENASES: STRUCTURE/FUNCTION, GENETIC POLYMORPHISMS AND ROLE IN DRUG METABOLISM.PHARMACOLOGY & THERAPEUTICS. VOL. 106. ISSUE 3. P. 357 -387 188 70% 202
2 CASHMAN, JR , ZHANG, J , (2006) HUMAN FLAVIN-CONTAINING MONOOXYGENASES.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 46. ISSUE . P. 65 -100 102 78% 115
3 PHILLIPS, IR , SHEPHARD, EA , (2017) DRUG METABOLISM BY FLAVIN-CONTAINING MONOOXYGENASES OF HUMAN AND MOUSE.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 13. ISSUE 2. P. 167 -181 101 70% 0
4 KOUKOURITAKI, SB , HINES, RN , (2005) FLAVIN-CONTAINING MONOOXYGENASE GENETIC POLYMORPHISM: IMPACT ON CHEMICAL METABOLISM AND DRUG DEVELOPMENT.PHARMACOGENOMICS. VOL. 6. ISSUE 8. P. 807-822 69 93% 36
5 PHILLIPS, IR , SHEPHARD, EA , (2008) FLAVIN-CONTAINING MONOOXYGENASES: MUTATIONS, DISEASE AND DRUG RESPONSE.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 29. ISSUE 6. P. 294-301 61 91% 54
6 CASHMAN, JR , ZHANG, J , (2002) INTERINDIVIDUAL DIFFERENCES OF HUMAN FLAVIN-CONTAINING MONOOXYGENASE 3: GENETIC POLYMORPHISMS AND FUNCTIONAL VARIATION.DRUG METABOLISM AND DISPOSITION. VOL. 30. ISSUE 10. P. 1043 -1052 71 85% 57
7 CASHMAN, JR , (1995) STRUCTURAL AND CATALYTIC PROPERTIES OF THE MAMMALIAN FLAVIN-CONTAINING MONOOXYGENASE.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 8. ISSUE 2. P. 165-181 98 73% 105
8 MOTIKA, MS , ZHANG, J , CASHMAN, JR , (2007) FLAVIN-CONTAINING MONOOXYGENASE 3 AND HUMAN DISEASE.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 3. ISSUE 6. P. 831-845 63 85% 13
9 FENNEMA, D , PHILLIPS, IR , SHEPHARD, EA , (2016) TRIMETHYLAMINE AND TRIMETHYLAMINE N-OXIDE, A FLAVIN-CONTAINING MONOOXYGENASE 3 (FMO3)-MEDIATED HOST-MICROBIOME METABOLIC AXIS IMPLICATED IN HEALTH AND DISEASE.DRUG METABOLISM AND DISPOSITION. VOL. 44. ISSUE 11. P. 1839 -1850 74 54% 1
10 BAIN, MA , FORNASINI, G , EVANS, AM , (2005) TRIMETHYLAMINE: METABOLIC, PHARMACOKINETIC AND SAFETY ASPECTS.CURRENT DRUG METABOLISM. VOL. 6. ISSUE 3. P. 227-240 80 63% 34

Classes with closest relation at Level 2


Rank Class id link
1 1923 BAEYER VILLIGER OXIDATION//BAEYER VILLIGER MONOOXYGENASE//CYCLOHEXANONE MONOOXYGENASE
2 2833 BREADFRUIT//PRIMARY AROMATIC AMINES//ALIPHATIC AMINES
3 1485 METABOLOMICS//METABONOMICS//METABOLIC PROFILING
4 415 CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR
5 3764 ETHYLENETHIOUREA//IODINE AZIDE REACTION//MANCOZEB
6 2281 N NITROSAMINES//NITROSAMINES//NDMA
7 1504 CARNITINE//L CARNITINE//TRIMETAZIDINE
8 2110 SULFOXIDES//SULFOXIMINES//DIOXIRANES
9 278 PROBIOTICS//MICROBIOTA//GUT MICROBIOTA
10 2470 OCCUPATIONAL ASTHMA//TOLUENE DIISOCYANATE//WORK RELATED ASTHMA

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