Class information for:
Level 2: HEPATOCYTE GROWTH FACTOR//C MET//HGF

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2452 4045 42.9 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
2452 2             HEPATOCYTE GROWTH FACTOR//C MET//HGF 4045
303 1                   HEPATOCYTE GROWTH FACTOR//C MET//HGF 3689
23172 1                   RON//MACROPHAGE STIMULATING PROTEIN//RON RECEPTOR 356

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEPATOCYTE GROWTH FACTOR authKW 2727916 20% 45% 795
2 C MET authKW 2452457 14% 56% 580
3 HGF authKW 992523 8% 41% 323
4 MET authKW 717332 7% 35% 272
5 SCATTER FACTOR authKW 500009 2% 68% 97
6 C MET INHIBITOR authKW 321996 1% 89% 48
7 RON authKW 320342 2% 54% 79
8 NK4 authKW 305646 1% 90% 45
9 HGF SF authKW 285949 1% 63% 60
10 HEPATOCYTE GROWTH FACTOR HGF authKW 243217 2% 46% 70

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 14614 32% 0% 1293
2 Cell Biology 4714 19% 0% 764
3 Biochemistry & Molecular Biology 2254 23% 0% 932
4 Gastroenterology & Hepatology 1093 6% 0% 232
5 Medicine, Research & Experimental 693 6% 0% 244
6 Pathology 673 4% 0% 175
7 Biophysics 550 5% 0% 215
8 Genetics & Heredity 432 6% 0% 232
9 Chemistry, Medicinal 332 3% 0% 140
10 Urology & Nephrology 229 3% 0% 120

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL REGENERAT MED 241393 2% 36% 88
2 COURSE ADV MED 210660 1% 57% 49
3 KRINGLE PHARMA JOINT REGENERAT DRUG DISCO 154789 1% 71% 29
4 TUMOR DYNAM REGULAT 91953 1% 42% 29
5 ONCOL BIOCHEM 76237 1% 42% 24
6 BIOCHEMBIOMED 60376 0% 100% 8
7 IRCC 52558 1% 27% 26
8 CANC TREATMENT IRCC 37364 1% 24% 21
9 EXPT CLIN MOL ONCOL 36976 0% 70% 7
10 PK ANALYT CHEM 30188 0% 100% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENE 6770 3% 1% 129
2 MOLECULAR CANCER THERAPEUTICS 3680 1% 1% 45
3 CLINICAL CANCER RESEARCH 3455 2% 1% 84
4 CURRENT SIGNAL TRANSDUCTION THERAPY 2800 0% 4% 9
5 HEPATOLOGY 2190 1% 1% 60
6 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2099 4% 0% 144
7 CANCER RESEARCH 1591 2% 0% 95
8 CLINICAL & EXPERIMENTAL METASTASIS 1476 0% 1% 20
9 JOURNAL OF THORACIC ONCOLOGY 1450 1% 1% 23
10 GROWTH FACTORS 1129 0% 1% 11

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HEPATOCYTE GROWTH FACTOR 2727916 20% 45% 795 Search HEPATOCYTE+GROWTH+FACTOR Search HEPATOCYTE+GROWTH+FACTOR
2 C MET 2452457 14% 56% 580 Search C+MET Search C+MET
3 HGF 992523 8% 41% 323 Search HGF Search HGF
4 MET 717332 7% 35% 272 Search MET Search MET
5 SCATTER FACTOR 500009 2% 68% 97 Search SCATTER+FACTOR Search SCATTER+FACTOR
6 C MET INHIBITOR 321996 1% 89% 48 Search C+MET+INHIBITOR Search C+MET+INHIBITOR
7 RON 320342 2% 54% 79 Search RON Search RON
8 NK4 305646 1% 90% 45 Search NK4 Search NK4
9 HGF SF 285949 1% 63% 60 Search HGF+SF Search HGF+SF
10 HEPATOCYTE GROWTH FACTOR HGF 243217 2% 46% 70 Search HEPATOCYTE+GROWTH+FACTOR+HGF Search HEPATOCYTE+GROWTH+FACTOR+HGF

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CHRISTENSEN, JG , BURROWS, J , SALGIA, R , (2005) C-MET AS A TARGET FOR HUMAN CANCER AND CHARACTERIZATION OF INHIBITORS FOR THERAPEUTIC INTERVENTION.CANCER LETTERS. VOL. 225. ISSUE 1. P. 1-26 180 87% 306
2 GHERARDI, E , BIRCHMEIER, W , BIRCHMEIER, C , WOUDE, GV , (2012) TARGETING MET IN CANCER: RATIONALE AND PROGRESS.NATURE REVIEWS CANCER. VOL. 12. ISSUE 2. P. 89 -103 114 66% 504
3 JIANG, W , HISCOX, S , MATSUMOTO, K , NAKAMURA, T , (1999) HEPATOCYTE GROWTH FACTOR SCATTER FACTOR, ITS MOLECULAR, CELLULAR AND CLINICAL IMPLICATIONS IN CANCER.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 29. ISSUE 3. P. 209 -248 250 74% 183
4 YAO, HP , ZHOU, YQ , ZHANG, RW , WANG, MH , (2013) MSP-RON SIGNALLING IN CANCER: PATHOGENESIS AND THERAPEUTIC POTENTIAL.NATURE REVIEWS CANCER. VOL. 13. ISSUE 7. P. 466-481 135 84% 36
5 MOLNARFI, N , BENKHOUCHA, M , FUNAKOSHI, H , NAKAMURA, T , LALIVE, PH , (2015) HEPATOCYTE GROWTH FACTOR: A REGULATOR OF INFLAMMATION AND AUTOIMMUNITY.AUTOIMMUNITY REVIEWS. VOL. 14. ISSUE 4. P. 293 -303 134 75% 15
6 MAROUN, CR , ROWLANDS, T , (2014) THE MET RECEPTOR TYROSINE KINASE: A KEY PLAYER IN ONCOGENESIS AND DRUG RESISTANCE.PHARMACOLOGY & THERAPEUTICS. VOL. 142. ISSUE 3. P. 316 -338 140 65% 35
7 FUNAKOSHI, H , NAKAMURA, T , (2003) HEPATOCYTE GROWTH FACTOR: FROM DIAGNOSIS TO CLINICAL APPLICATIONS.CLINICA CHIMICA ACTA. VOL. 327. ISSUE 1-2. P. 1-23 144 89% 126
8 COMOGLIO, PM , GIORDANO, S , TRUSOLINO, L , (2008) DRUG DEVELOPMENT OF MET INHIBITORS: TARGETING ONCOGENE ADDICTION AND EXPEDIENCE.NATURE REVIEWS DRUG DISCOVERY. VOL. 7. ISSUE 6. P. 504 -516 96 77% 417
9 VAN DER VOORT, R , TAHER, TEI , DERKSEN, PWB , SPAARGAREN, M , VAN DER NEUT, R , PALS, ST , (2000) THE HEPATOCYTE GROWTH FACTOR/MET PATHWAY IN DEVELOPMENT, TUMORIGENESIS, AND B-CELL DIFFERENTIATION.ADVANCES IN CANCER RESEARCH, VOL 79. VOL. 79. ISSUE . P. 39-90 244 61% 72
10 PETERS, S , ADJEI, AA , (2012) MET: A PROMISING ANTICANCER THERAPEUTIC TARGET.NATURE REVIEWS CLINICAL ONCOLOGY. VOL. 9. ISSUE 6. P. 314 -326 101 76% 120

Classes with closest relation at Level 2


Rank Class id link
1 4187 MACC1//HEPATOMA DERIVED GROWTH FACTOR//METASTASIS ASSOCIATED IN COLON CANCER 1
2 1717 GEFITINIB//EGFR MUTATION//MIDKINE
3 1310 HEPATIC STELLATE CELLS//LIVER FIBROSIS//LIVER REGENERATION
4 1648 EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA
5 2107 LYMPHANGIOGENESIS//VEGF C//PODOPLANIN
6 1549 CYCLOTIDES//BOWMAN BIRK INHIBITOR//TRYPSIN INHIBITOR
7 2641 EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL
8 908 BIOARTIFICIAL LIVER//HEPATOCYTES//HEPATOCYTE TRANSPLANTATION
9 2572 UROKINASE RECEPTOR//UPAR//UPA
10 1804 ARTERIOGENESIS//COLLATERAL CIRCULATION//TRANSMYOCARDIAL LASER REVASCULARIZATION

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