Class information for:
Level 2: TOXICOLOGIC PATHOLOGY//RASH2 MICE//HISTORICAL CONTROL DATA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2445 4057 32.2 52%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
2445 2             TOXICOLOGIC PATHOLOGY//RASH2 MICE//HISTORICAL CONTROL DATA 4057
8645 1                   POLY 3 TEST//HISTORICAL CONTROL DATA//NATIONAL TOXICOLOGY PROGRAM 1232
14611 1                   IMMUNOTOXICITY//IMMUNOTOXICOLOGY//IMMUNE FUNCTION TESTS 760
19046 1                   TGN1412//MICROMINIPIG//MINIPIG 525
23170 1                   RASH2 MICE//RASH2 MOUSE//RASH2 356
26520 1                   DRUG INDUCED VASCULAR INJURY//ARTERIAL TOXICITY//MEDIAL NECROSIS 252
27113 1                   SAFETY PHARMACOLOGY//TAIL CUFF METHOD//JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 237
29299 1                   GPX3//CMB GENET//GLUTATHIONE PEROXIDASE 3 189
30988 1                   AGING ANIMAL MODEL//F344 N RAT//PROTOCOL STUDY 160
32185 1                   INFORMAT TECHNOL DATABASES//ARMAMENTARIUM//NACAD 142
32845 1                   MARKING LIKE BEHAVIOR//SCENT GLAND//ABDOMINAL PAD 133
36901 1                   BRILLANTAISIA NITENS//HAEMATINIC ACTIVITY//METHYLENE CHLORIDE METHANOL EXTRACT 71

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 TOXICOLOGIC PATHOLOGY journal 420911 9% 15% 377
2 RASH2 MICE authKW 123468 0% 86% 19
3 HISTORICAL CONTROL DATA authKW 118504 1% 75% 21
4 CARCINOGENICITY TESTING authKW 117061 1% 68% 23
5 TGN1412 authKW 104467 0% 73% 19
6 TOXICOLOGY WoSSC 99005 47% 1% 1887
7 RASH2 MOUSE authKW 86750 0% 82% 14
8 CARCINOGENICITY authKW 84104 3% 10% 107
9 MICROMINIPIG authKW 80613 0% 71% 15
10 IMMUNOTOXICITY authKW 76645 2% 10% 99

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Toxicology 99005 47% 1% 1887
2 Pathology 10604 15% 0% 604
3 Medicine, Legal 5012 4% 0% 156
4 Pharmacology & Pharmacy 4302 21% 0% 846
5 Veterinary Sciences 1917 9% 0% 351
6 Oncology 1025 10% 0% 415
7 Statistics & Probability 1023 4% 0% 178
8 Public, Environmental & Occupational Health 956 8% 0% 308
9 Environmental Sciences 673 8% 0% 326
10 Mathematical & Computational Biology 416 2% 0% 88

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENVIRONM CARCINOGENESIS MUTAGENESIS 48771 1% 31% 21
2 CMB GENET 45515 0% 55% 11
3 PRECLIN ASSESSMENT GRP 45148 0% 100% 6
4 VET HISTOPATHOL 30087 0% 40% 10
5 MED MED DEVICES 24573 0% 47% 7
6 TOXICOL SAFETY ASSESSMENT 23431 0% 35% 9
7 INFORMAT TECHNOL DATABASES 22574 0% 100% 3
8 MED EVALUAT BOARD NETHERLANDS 22574 0% 100% 3
9 PRECLIN ASSESSMENT GRP MED EVALUAT BOARD 22574 0% 100% 3
10 ANIM IL AGING 20898 0% 56% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TOXICOLOGIC PATHOLOGY 420911 9% 15% 377
2 REGULATORY TOXICOLOGY AND PHARMACOLOGY 61981 4% 5% 155
3 JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 35069 2% 6% 73
4 FUNDAMENTAL AND APPLIED TOXICOLOGY 27475 2% 4% 88
5 JOURNAL OF TOXICOLOGIC PATHOLOGY 23971 1% 10% 33
6 JOURNAL OF ENVIRONMENTAL PATHOLOGY AND TOXICOLOGY 16322 0% 11% 20
7 BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY 14844 1% 6% 32
8 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 14655 1% 3% 60
9 JOURNAL OF IMMUNOTOXICOLOGY 13325 1% 6% 29
10 INTERNATIONAL JOURNAL OF TOXICOLOGY 12496 1% 4% 44

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RASH2 MICE 123468 0% 86% 19 Search RASH2+MICE Search RASH2+MICE
2 HISTORICAL CONTROL DATA 118504 1% 75% 21 Search HISTORICAL+CONTROL+DATA Search HISTORICAL+CONTROL+DATA
3 CARCINOGENICITY TESTING 117061 1% 68% 23 Search CARCINOGENICITY+TESTING Search CARCINOGENICITY+TESTING
4 TGN1412 104467 0% 73% 19 Search TGN1412 Search TGN1412
5 RASH2 MOUSE 86750 0% 82% 14 Search RASH2+MOUSE Search RASH2+MOUSE
6 CARCINOGENICITY 84104 3% 10% 107 Search CARCINOGENICITY Search CARCINOGENICITY
7 MICROMINIPIG 80613 0% 71% 15 Search MICROMINIPIG Search MICROMINIPIG
8 IMMUNOTOXICITY 76645 2% 10% 99 Search IMMUNOTOXICITY Search IMMUNOTOXICITY
9 POLY 3 TEST 75247 0% 100% 10 Search POLY+3+TEST Search POLY+3+TEST
10 RASH2 70034 0% 85% 11 Search RASH2 Search RASH2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 EASTMOND, DA , VULIMIRI, SV , FRENCH, JE , SONAWANE, B , (2013) THE USE OF GENETICALLY MODIFIED MICE IN CANCER RISK ASSESSMENT: CHALLENGES AND LIMITATIONS.CRITICAL REVIEWS IN TOXICOLOGY. VOL. 43. ISSUE 8. P. 611 -631 68 70% 4
2 HAYES, AW , DAYAN, AD , HALL, WC , KODELL, RL , WILLIAMS, GM , WADDELL, WD , SLESINSKI, RS , KRUGER, CL , (2011) A REVIEW OF MAMMALIAN CARCINOGENICITY STUDY DESIGN AND POTENTIAL EFFECTS OF ALTERNATE TEST PROCEDURES ON THE SAFETY EVALUATION OF FOOD INGREDIENTS.REGULATORY TOXICOLOGY AND PHARMACOLOGY. VOL. 60. ISSUE 1. P. S1 -S34 70 65% 10
3 ZACCARIA, KJ , MCCLURE, PR , (2013) USING IMMUNOTOXICITY INFORMATION TO IMPROVE CANCER RISK ASSESSMENT FOR POLYCYCLIC AROMATIC HYDROCARBON MIXTURES.INTERNATIONAL JOURNAL OF TOXICOLOGY. VOL. 32. ISSUE 4. P. 236 -250 63 63% 4
4 MARONE, PA , HALL, WC , HAYES, AW , (2014) REASSESSING THE TWO-YEAR RODENT CARCINOGENICITY BIOASSAY: A REVIEW OF THE APPLICABILITY TO HUMAN RISK AND CURRENT PERSPECTIVES.REGULATORY TOXICOLOGY AND PHARMACOLOGY. VOL. 68. ISSUE 1. P. 108-118 58 50% 10
5 STORER, RD , SISTARE, FD , REDDY, MV , DEGEORGE, JJ , (2010) AN INDUSTRY PERSPECTIVE ON THE UTILITY OF SHORT-TERM CARCINOGENICITY TESTING IN TRANSGENIC MICE IN PHARMACEUTICAL DEVELOPMENT.TOXICOLOGIC PATHOLOGY. VOL. 38. ISSUE 1. P. 51-61 43 66% 19
6 ETTLIN, RA , PRENTICE, DE , (2002) UNEXPECTED TUMOUR FINDINGS IN LIFETIME RODENT BIOASSAY STUDIES - WHAT TO DO?.TOXICOLOGY LETTERS. VOL. 128. ISSUE 1-3. P. 17 -33 70 50% 7
7 KREWSKI, D , GAYLOR, DW , SOMS, AP , SZYSZKOWICZ, M , (1993) AN OVERVIEW OF THE REPORT - CORRELATION BETWEEN CARCINOGENIC POTENCY AND THE MAXIMUM TOLERATED DOSE - IMPLICATIONS FOR RISK ASSESSMENT.RISK ANALYSIS. VOL. 13. ISSUE 4. P. 383-398 60 72% 23
8 GREIM, H , GELBKE, HP , REUTER, U , THIELMANN, HW , EDLER, L , (2003) EVALUATION OF HISTORICAL CONTROL DATA IN CARCINOGENICITY STUDIES.HUMAN & EXPERIMENTAL TOXICOLOGY. VOL. 22. ISSUE 10. P. 541-549 36 84% 19
9 REYNAUD, S , DESCHAUX, P , (2006) THE EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBONS ON THE IMMUNE SYSTEM OF FISH: A REVIEW.AQUATIC TOXICOLOGY. VOL. 77. ISSUE 2. P. 229 -238 43 48% 150
10 PRITCHARD, JB , FRENCH, JE , DAVIS, BJ , HASEMAN, JK , (2003) THE ROLE OF TRANSGENIC MOUSE MODELS IN CARCINOGEN IDENTIFICATION.ENVIRONMENTAL HEALTH PERSPECTIVES. VOL. 111. ISSUE 4. P. 444-454 40 60% 74

Classes with closest relation at Level 2


Rank Class id link
1 2711 BENCHMARK DOSE//UNCERTAINTY FACTORS//WORKER NOTIFICATION
2 3033 CARCINOGENESIS//HEPATOCARCINOGENESIS//MEDIUM TERM BIOASSAY
3 3384 CIGARETTE SMOKE//ENVIRONMENTAL CIGARETTE SMOKE//LUNG TUMOR
4 469 MUTATION RESEARCH//MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS//COMET ASSAY
5 2782 NUCLEAR WORKERS//MULTIPLE PRIMARY MALIGNANCIES//RADIAT EPIDEMIOL BRANCH
6 3959 HORMESIS//U SHAPED//J SHAPED
7 2528 CARCINOGENESIS//CELL TRANSFORMATION ASSAY//BHAS 42 CELLS
8 2640 EMBRYONIC STEM CELL TEST//GLYCOL ETHERS//2 BUTOXYETHANOL
9 3094 ANIMAL EXPERIMENTATION//ATLA-ALTERNATIVES TO LABORATORY ANIMALS//JOURNAL OF AGRICULTURAL & ENVIRONMENTAL ETHICS
10 908 BIOARTIFICIAL LIVER//HEPATOCYTES//HEPATOCYTE TRANSPLANTATION

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