Class information for:
Level 1: DRUG INDUCED VASCULAR INJURY//ARTERIAL TOXICITY//MEDIAL NECROSIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
26520 252 29.7 45%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
2445 2             TOXICOLOGIC PATHOLOGY//RASH2 MICE//HISTORICAL CONTROL DATA 4057
26520 1                   DRUG INDUCED VASCULAR INJURY//ARTERIAL TOXICITY//MEDIAL NECROSIS 252

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG INDUCED VASCULAR INJURY authKW 861665 3% 89% 8
2 ARTERIAL TOXICITY authKW 363516 1% 100% 3
3 MEDIAL NECROSIS authKW 335547 2% 46% 6
4 MEDIAL HEMORRHAGE authKW 242344 1% 100% 2
5 TOXICOL COMPARAT MED address 218107 1% 60% 3
6 CI 1044 authKW 161561 1% 67% 2
7 PHYSIOL PAROI ARTERIELLE address 161561 1% 67% 2
8 ACTIVATION AND DEGRANULATION OF MAST CELL authKW 121172 0% 100% 1
9 ACTIVATION OF ENDOTHELIAL CELL AND MACROPHAGE authKW 121172 0% 100% 1
10 AGE DEPENDENT ENDOTHELIAL DYSFUNCTION authKW 121172 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 3750 37% 0% 92
2 Pathology 3009 31% 0% 78
3 Pharmacology & Pharmacy 310 22% 0% 56
4 Cardiac & Cardiovascular System 150 11% 0% 27
5 Medicine, General & Internal 120 12% 0% 29
6 Peripheral Vascular Diseases 80 6% 0% 15
7 Veterinary Sciences 41 6% 0% 14
8 Urology & Nephrology 31 4% 0% 10
9 Anatomy & Morphology 27 2% 0% 4
10 Emergency Medicine 5 1% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TOXICOL COMPARAT MED 218107 1% 60% 3
2 PHYSIOL PAROI ARTERIELLE 161561 1% 67% 2
3 ANESTHET CRIT CARE ADDICT DRUG PROD HFD170 121172 0% 100% 1
4 CARDIORENAL DRUG PROD HFD110 121172 0% 100% 1
5 NEPHROL HYPERTENS DIALYSES 121172 0% 100% 1
6 PULM DRUG PROD HFD570 121172 0% 100% 1
7 RECH SCI FORMAT RECH EVOLUT 3092 121172 0% 100% 1
8 TOXICOL US 121172 0% 100% 1
9 BIOMARKER RD 60585 0% 50% 1
10 HOSP UNIV 12B 60585 0% 50% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TOXICOLOGIC PATHOLOGY 109949 19% 2% 48
2 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 3558 7% 0% 18
3 BRITISH JOURNAL OF EXPERIMENTAL PATHOLOGY 2254 2% 0% 4
4 FUNDAMENTAL AND APPLIED TOXICOLOGY 1427 2% 0% 5
5 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 1049 2% 0% 4
6 VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY 1018 2% 0% 4
7 ARCHIVES OF TOXICOLOGY 994 2% 0% 6
8 DRUG INTELLIGENCE & CLINICAL PHARMACY 978 1% 0% 3
9 TIERAERZTLICHE UMSCHAU 943 1% 0% 3
10 TOXICOLOGY LETTERS 919 3% 0% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DRUG INDUCED VASCULAR INJURY 861665 3% 89% 8 Search DRUG+INDUCED+VASCULAR+INJURY Search DRUG+INDUCED+VASCULAR+INJURY
2 ARTERIAL TOXICITY 363516 1% 100% 3 Search ARTERIAL+TOXICITY Search ARTERIAL+TOXICITY
3 MEDIAL NECROSIS 335547 2% 46% 6 Search MEDIAL+NECROSIS Search MEDIAL+NECROSIS
4 MEDIAL HEMORRHAGE 242344 1% 100% 2 Search MEDIAL+HEMORRHAGE Search MEDIAL+HEMORRHAGE
5 CI 1044 161561 1% 67% 2 Search CI+1044 Search CI+1044
6 ACTIVATION AND DEGRANULATION OF MAST CELL 121172 0% 100% 1 Search ACTIVATION+AND+DEGRANULATION+OF+MAST+CELL Search ACTIVATION+AND+DEGRANULATION+OF+MAST+CELL
7 ACTIVATION OF ENDOTHELIAL CELL AND MACROPHAGE 121172 0% 100% 1 Search ACTIVATION+OF+ENDOTHELIAL+CELL+AND+MACROPHAGE Search ACTIVATION+OF+ENDOTHELIAL+CELL+AND+MACROPHAGE
8 AGE DEPENDENT ENDOTHELIAL DYSFUNCTION 121172 0% 100% 1 Search AGE+DEPENDENT+ENDOTHELIAL+DYSFUNCTION Search AGE+DEPENDENT+ENDOTHELIAL+DYSFUNCTION
9 ANTI AND PRO INFLAMMATORY EFFECTS 121172 0% 100% 1 Search ANTI+AND+PRO+INFLAMMATORY+EFFECTS Search ANTI+AND+PRO+INFLAMMATORY+EFFECTS
10 APOPTOSIS OF ENDOTHELIAL AND SMOOTH MUSCLE CELLS 121172 0% 100% 1 Search APOPTOSIS+OF+ENDOTHELIAL+AND+SMOOTH+MUSCLE+CELLS Search APOPTOSIS+OF+ENDOTHELIAL+AND+SMOOTH+MUSCLE+CELLS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DALMAS, DA , SCICCHITANO, MS , MULLINS, D , HUGHES-EARLE, A , TATSUOKA, K , MAGID-SLAV, M , FRAZIER, KS , THOMAS, HC , (2011) POTENTIAL CANDIDATE GENOMIC BIOMARKERS OF DRUG INDUCED VASCULAR INJURY IN THE RAT.TOXICOLOGY AND APPLIED PHARMACOLOGY. VOL. 257. ISSUE 2. P. 284-300 19 70% 6
2 BACARES, MEP , (2016) SAMPLING THE RAT MESENTERIC ARTERY: A SIMPLE TECHNIQUE.TOXICOLOGIC PATHOLOGY. VOL. 44. ISSUE 8. P. 1166 -1169 13 93% 0
3 JONES, HB , BJORKMAN, JA , SCHOFIELD, J , (2013) CORONARY AND SYSTEMIC ARTERIAL PHYSIOLOGY AND IMMUNOHISTOCHEMICAL MARKERS RELATED TO EARLY CORONARY ARTERIAL LESIONS IN BEAGLE DOGS GIVEN THE POTASSIUM CHANNEL OPENER, ZD6169, OR THE ENDOTHELIN RECEPTOR ANTAGONIST, ZD1611.TOXICOLOGIC PATHOLOGY. VOL. 41. ISSUE 5. P. 722-735 17 65% 2
4 MIKAELIAN, I , CAMERON, M , DALMAS, DA , ENERSON, BE , GONZALEZ, RJ , GUIONAUD, S , HOFFMANN, PK , KING, NMP , LAWTON, MP , SCICCHITANO, MS , ET AL (2014) NONCLINICAL SAFETY BIOMARKERS OF DRUG-INDUCED VASCULAR INJURY: CURRENT STATUS AND BLUEPRINT FOR THE FUTURE.TOXICOLOGIC PATHOLOGY. VOL. 42. ISSUE 4. P. 635 -657 46 21% 6
5 MECKLENBURG, L , HEUSER, A , JUENGLING, T , KOHLER, M , FOELL, R , OCKERT, D , TUCH, K , BODE, G , (2006) MESENTERITIS PRECEDES VASCULITIS IN THE RAT MESENTERY AFTER SUBACUTE ADMINISTRATION OF A PHOSPHODIESTERASE TYPE 4 INHIBITOR.TOXICOLOGY LETTERS. VOL. 163. ISSUE 1. P. 54-64 16 73% 22
6 BENDJAMA, K , GUIONAUD, S , ARAS, G , ARBER, N , BADIMON, L , BAMBERGER, U , BRATFALEAN, D , BROTT, D , DAVID, M , DOESSEGGER, L , ET AL (2014) TRANSLATION STRATEGY FOR THE QUALIFICATION OF DRUG-INDUCED VASCULAR INJURY BIOMARKERS.TOXICOLOGIC PATHOLOGY. VOL. 42. ISSUE 4. P. 658-671 24 38% 3
7 LOUDEN, C , MORGAN, DG , (2001) PATHOLOGY AND PATHOPHYSIOLOGY OF DRUG-INDUCED ARTERIAL INJURY IN LABORATORY ANIMALS AND ITS IMPLICATIONS ON THE EVALUATION OF NOVEL CHEMICAL ENTITIES FOR HUMAN CLINICAL TRIALS.PHARMACOLOGY & TOXICOLOGY. VOL. 89. ISSUE 4. P. 158-170 26 50% 16
8 FRAZIER, KS , ENGELHARDT, JA , FANT, P , GUIONAUD, S , HENRY, SP , LEACH, MW , LOUDEN, C , SCICCHITANO, MS , WEAVER, JL , ZABKA, TS , (2015) SCIENTIFIC AND REGULATORY POLICY COMMITTEE POINTS-TO-CONSIDER PAPER*: DRUG-INDUCED VASCULAR INJURY ASSOCIATED WITH NONSMALL MOLECULE THERAPEUTICS IN PRECLINICAL DEVELOPMENT: PART I. BIOTHERAPEUTICS.TOXICOLOGIC PATHOLOGY. VOL. 43. ISSUE 7. P. 915 -934 38 23% 0
9 HANTON, G , SOBRY, C , DAGUES, N , PROVOST, JP , LE NET, JL , COMBY, P , CHEVALIER, S , (2008) CHARACTERISATION OF THE VASCULAR AND INFLAMMATORY LESIONS INDUCED BY THE PDE4 INHIBITOR CI-1044 IN THE DOG.TOXICOLOGY LETTERS. VOL. 179. ISSUE 1. P. 15-22 18 56% 9
10 BROTT, DA , RICHARDSON, RJ , LOUDEN, CS , (2012) EVIDENCE FOR THE NITRIC OXIDE PATHWAY AS A POTENTIAL MODE OF ACTION IN FENOLDOPAM-INDUCED VASCULAR INJURY.TOXICOLOGIC PATHOLOGY. VOL. 40. ISSUE 6. P. 874-886 20 42% 9

Classes with closest relation at Level 1


Rank Class id link
1 36617 IRON AND ZINC DETERMINATION//PHARMACEUTICAL MULTIVITAMIN PREPARATIONS//2 MERCAPTO 5 2 4 DIHYDROXY 5 CARBOXYPHENYLAZO 1 1 3 4 TIADIAZOLE
2 32060 CEPHALORIDINE//PHARMACEUT SCI TOXICOL CLIN PHARMACOL//AHMANSON ELE ON MICROSCOPY ADV IMAGING
3 15714 ARTERIAL PRESSURE RELATED NEURON//NOCICEPTION RELATED NEURON//NUCLEUS RETICULARIS GIGANTOCELLULARIS
4 7570 ANDROGENETIC ALOPECIA//FEMALE PATTERN HAIR LOSS//MINOXIDIL
5 32185 INFORMAT TECHNOL DATABASES//ARMAMENTARIUM//NACAD
6 30382 EOSINOPHILIC PLEURAL EFFUSION//PLEURAL FLUID EOSINOPHILIA//DRUG INDUCED ADVERSE EFFECTS IN LUNG
7 27113 SAFETY PHARMACOLOGY//TAIL CUFF METHOD//JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
8 31382 6 SULFANILAMIDOINDAZOLE//PHYSIOL ROSWELL PK//ALPHA2 PREGNANCY ASSOCIATED GLYCOPROTEIN
9 33105 ECTOPIC ADRENAL//ECTOPIC ADRENAL TISSUE//ADRENOHEPATIC FUSION
10 12019 HYPERTENSIVE EMERGENCY//HYPERTENSIVE URGENCY//HYPERTENSIVE CRISIS

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