Class information for:
Level 1: POLY 3 TEST//HISTORICAL CONTROL DATA//NATIONAL TOXICOLOGY PROGRAM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8645 1232 33.7 44%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
116 3       MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS 70215
2445 2             TOXICOLOGIC PATHOLOGY//RASH2 MICE//HISTORICAL CONTROL DATA 4057
8645 1                   POLY 3 TEST//HISTORICAL CONTROL DATA//NATIONAL TOXICOLOGY PROGRAM 1232

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 POLY 3 TEST authKW 247836 1% 100% 10
2 HISTORICAL CONTROL DATA authKW 226579 1% 57% 16
3 NATIONAL TOXICOLOGY PROGRAM authKW 190336 2% 40% 19
4 TD50 authKW 187419 1% 69% 11
5 CARCINOGENIC POTENCY authKW 162663 1% 41% 16
6 TUMOR INCIDENCE RATE authKW 127457 0% 86% 6
7 RODENT BIOASSAY authKW 111517 1% 50% 9
8 CARCINOGENICITY STUDIES authKW 100364 1% 45% 9
9 ADDITIVE FAILURE RATE authKW 99134 0% 100% 4
10 INTERVAL SACRIFICE authKW 99134 0% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Toxicology 36817 51% 0% 633
2 Medicine, Legal 7726 9% 0% 105
3 Statistics & Probability 3833 14% 0% 172
4 Public, Environmental & Occupational Health 2156 18% 0% 222
5 Pathology 2102 12% 0% 150
6 Mathematical & Computational Biology 1456 7% 0% 81
7 Social Sciences, Mathematical Methods 1346 4% 0% 52
8 Environmental Sciences 1020 15% 0% 189
9 Pharmacology & Pharmacy 709 16% 0% 199
10 Mathematics, Interdisciplinary Applications 488 5% 0% 61

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PRECLIN ASSESSMENT GRP 66087 0% 67% 4
2 ILSI EUROPE 49567 0% 100% 2
3 BIOMETRY RISK ASSESSMENT 35044 1% 9% 15
4 MED EVALUAT BOARD NETHERLANDS 33043 0% 67% 2
5 JEFFERSON S 25808 0% 21% 5
6 ADDIT TOXICOL P 24784 0% 100% 1
7 ADM DRUG EVALUAT 24784 0% 100% 1
8 ANIM PLANT HLTH INSPECT SECT 24784 0% 100% 1
9 DIRECT PROD REGLEMENTES 24784 0% 100% 1
10 DIRECTORATE EPIDEMIOL HLTH SCI 24784 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REGULATORY TOXICOLOGY AND PHARMACOLOGY 92138 8% 4% 104
2 TOXICOLOGIC PATHOLOGY 51917 6% 3% 73
3 JOURNAL OF ENVIRONMENTAL PATHOLOGY AND TOXICOLOGY 43608 1% 10% 18
4 FUNDAMENTAL AND APPLIED TOXICOLOGY 32922 4% 3% 53
5 RISK ANALYSIS 19510 4% 2% 49
6 ENVIRONMENTAL HEALTH PERSPECTIVES 15227 6% 1% 74
7 BIOMETRICS 14803 4% 1% 52
8 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 13775 3% 2% 32
9 JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY 11519 1% 3% 17
10 JOURNAL OF TOXICOLOGIC PATHOLOGY 7249 1% 3% 10

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 POLY 3 TEST 247836 1% 100% 10 Search POLY+3+TEST Search POLY+3+TEST
2 HISTORICAL CONTROL DATA 226579 1% 57% 16 Search HISTORICAL+CONTROL+DATA Search HISTORICAL+CONTROL+DATA
3 NATIONAL TOXICOLOGY PROGRAM 190336 2% 40% 19 Search NATIONAL+TOXICOLOGY+PROGRAM Search NATIONAL+TOXICOLOGY+PROGRAM
4 TD50 187419 1% 69% 11 Search TD50 Search TD50
5 CARCINOGENIC POTENCY 162663 1% 41% 16 Search CARCINOGENIC+POTENCY Search CARCINOGENIC+POTENCY
6 TUMOR INCIDENCE RATE 127457 0% 86% 6 Search TUMOR+INCIDENCE+RATE Search TUMOR+INCIDENCE+RATE
7 RODENT BIOASSAY 111517 1% 50% 9 Search RODENT+BIOASSAY Search RODENT+BIOASSAY
8 CARCINOGENICITY STUDIES 100364 1% 45% 9 Search CARCINOGENICITY+STUDIES Search CARCINOGENICITY+STUDIES
9 ADDITIVE FAILURE RATE 99134 0% 100% 4 Search ADDITIVE+FAILURE+RATE Search ADDITIVE+FAILURE+RATE
10 INTERVAL SACRIFICE 99134 0% 100% 4 Search INTERVAL+SACRIFICE Search INTERVAL+SACRIFICE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HAYES, AW , DAYAN, AD , HALL, WC , KODELL, RL , WILLIAMS, GM , WADDELL, WD , SLESINSKI, RS , KRUGER, CL , (2011) A REVIEW OF MAMMALIAN CARCINOGENICITY STUDY DESIGN AND POTENTIAL EFFECTS OF ALTERNATE TEST PROCEDURES ON THE SAFETY EVALUATION OF FOOD INGREDIENTS.REGULATORY TOXICOLOGY AND PHARMACOLOGY. VOL. 60. ISSUE 1. P. S1 -S34 56 52% 10
2 KREWSKI, D , GAYLOR, DW , SOMS, AP , SZYSZKOWICZ, M , (1993) AN OVERVIEW OF THE REPORT - CORRELATION BETWEEN CARCINOGENIC POTENCY AND THE MAXIMUM TOLERATED DOSE - IMPLICATIONS FOR RISK ASSESSMENT.RISK ANALYSIS. VOL. 13. ISSUE 4. P. 383-398 60 72% 23
3 ETTLIN, RA , PRENTICE, DE , (2002) UNEXPECTED TUMOUR FINDINGS IN LIFETIME RODENT BIOASSAY STUDIES - WHAT TO DO?.TOXICOLOGY LETTERS. VOL. 128. ISSUE 1-3. P. 17 -33 62 45% 7
4 GREIM, H , GELBKE, HP , REUTER, U , THIELMANN, HW , EDLER, L , (2003) EVALUATION OF HISTORICAL CONTROL DATA IN CARCINOGENICITY STUDIES.HUMAN & EXPERIMENTAL TOXICOLOGY. VOL. 22. ISSUE 10. P. 541-549 33 77% 19
5 KIM, W , AHN, H , MOON, H , (2007) A DOSE-RESPONSE TEST VIA CLOSED-FORM SOLUTIONS FOR CONSTRAINED MLES IN SURVIVAL/SACRIFICE EXPERIMENTS.STATISTICS IN MEDICINE. VOL. 26. ISSUE 3. P. 694-708 24 92% 0
6 LIN, T , GOLD, LS , FREEDMAN, D , (1995) CARCINOGENICITY TESTS AND INTERSPECIES CONCORDANCE.STATISTICAL SCIENCE. VOL. 10. ISSUE 4. P. 337-353 36 84% 4
7 HASEMAN, JK , (1995) DATA-ANALYSIS - STATISTICAL-ANALYSIS AND USE OF HISTORICAL CONTROL DATA.REGULATORY TOXICOLOGY AND PHARMACOLOGY. VOL. 21. ISSUE 1. P. 52-59 31 91% 29
8 PEDDADA, SD , DINSE, GE , KISSLING, GE , (2007) INCORPORATING HISTORICAL CONTROL DATA WHEN COMPARING TUMOR INCIDENCE RATES.JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION. VOL. 102. ISSUE 480. P. 1212-1220 20 91% 6
9 MARONE, PA , HALL, WC , HAYES, AW , (2014) REASSESSING THE TWO-YEAR RODENT CARCINOGENICITY BIOASSAY: A REVIEW OF THE APPLICABILITY TO HUMAN RISK AND CURRENT PERSPECTIVES.REGULATORY TOXICOLOGY AND PHARMACOLOGY. VOL. 68. ISSUE 1. P. 108-118 40 35% 10
10 HUFF, J , (2002) CHEMICALS STUDIED AND EVALUATED IN LONG-TERM CARCINOGENESIS BIOASSAYS BY BOTH THE RAMAZZINI FOUNDATION AND THE NATIONAL TOXICOLOGY PROGRAM - IN TRIBUTE TO CESARE MALTONI AND DAVID RALL.CARCINOGENESIS BIOASSAYS AND PROTECTING PUBLIC HEALTH. VOL. 982. ISSUE . P. 208-229 35 56% 26

Classes with closest relation at Level 1


Rank Class id link
1 23170 RASH2 MICE//RASH2 MOUSE//RASH2
2 10922 COMPUTATIONAL TOXICOLOGY//ICH M7//RODENT CARCINOGENICITY
3 32185 INFORMAT TECHNOL DATABASES//ARMAMENTARIUM//NACAD
4 15067 BENCHMARK DOSE//UNCERTAINTY FACTORS//NONCANCER RISK ASSESSMENT
5 31528 RED BOOK//PRESIDENTIAL COMMISSION//NATIONAL RESEARCH COUNCIL
6 37061 COUMARIN REDUCTONES//FLUORTENSIDE//PEPTIDES AND PROTEINS OF FETAL BRAIN
7 18907 MODELS OF CARCINOGENESIS//MVK MODEL//CESSATION LAG
8 32845 MARKING LIKE BEHAVIOR//SCENT GLAND//ABDOMINAL PAD
9 29299 GPX3//CMB GENET//GLUTATHIONE PEROXIDASE 3
10 30988 AGING ANIMAL MODEL//F344 N RAT//PROTOCOL STUDY

Go to start page