Class information for:
Level 2: HISTAMINE//HISTAMINE H 3 RECEPTOR//THIOPERAMIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1522 7482 33.0 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
686 3       HISTAMINE//HISTAMINE H 3 RECEPTOR//THIOPERAMIDE 8239
1522 2             HISTAMINE//HISTAMINE H 3 RECEPTOR//THIOPERAMIDE 7482
960 1                   HISTAMINE H 3 RECEPTOR//THIOPERAMIDE//H 3 RECEPTOR 2936
4836 1                   HISTAMINE H 4 RECEPTOR//HISTAMINE//JNJ7777120 1717
11769 1                   HISTAMINE H 2 RECEPTORS//CAS 76963 41 2//AGENTS AND ACTIONS 955
19312 1                   HISTAMINE INTOLERANCE//HISTAMINE N METHYLTRANSFERASE//HNMT 512
19530 1                   ARPROMIDINE//HISTAMINE H 2 RECEPTOR AGONISTS//H 2 AGONISTS 501
22791 1                   ANTIHISTAMINE H 1//CATTEDRA ENDOCRINOL PATOL CONSTITUZ//CIMETIDINE TOLERANCE TEST 368
24946 1                   HISTAMINE H 1 RECEPTOR//MOL STUDIES INCURABLE DIS//H 3 MEPYRAMINE 296
28878 1                   ANTIFERTIL INFERTIL//OVARIAN MAST CELLS//UTERINE MAST CELL 197

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 HISTAMINE authKW 1443238 19% 25% 1426
2 HISTAMINE H 3 RECEPTOR authKW 1152822 4% 93% 304
3 THIOPERAMIDE authKW 546532 2% 87% 154
4 H 3 RECEPTOR authKW 497949 2% 88% 138
5 HISTAMINE H 1 RECEPTOR authKW 374874 2% 58% 159
6 HISTAMINE RECEPTORS authKW 367680 2% 54% 168
7 HISTAMINE H 4 RECEPTOR authKW 293322 1% 90% 80
8 R ALPHA METHYLHISTAMINE authKW 253000 1% 89% 70
9 HISTIDINE DECARBOXYLASE authKW 183437 2% 39% 116
10 AGENTS AND ACTIONS journal 170940 5% 11% 367

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 29689 38% 0% 2808
2 Chemistry, Medicinal 4655 8% 0% 603
3 Neurosciences 4472 16% 0% 1222
4 Immunology 3175 12% 0% 862
5 Allergy 2790 3% 0% 228
6 Chemistry, Multidisciplinary 690 9% 0% 696
7 Behavioral Sciences 643 3% 0% 191
8 Cell Biology 581 7% 0% 495
9 Physiology 336 3% 0% 251
10 Medicine, Research & Experimental 334 4% 0% 278

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNITE NEUROBIOL PHARMACOL MOL 89865 1% 48% 46
2 U109 41766 0% 41% 25
3 PAUL BROCA 40604 0% 29% 34
4 R4MN 38292 0% 72% 13
5 PHARMACEUT MED CHEM 1 37965 0% 85% 11
6 GENET CELL IMMUNOBIOL 37103 1% 14% 64
7 TECHNOL BIOTECHNOL DRUGS 35656 0% 27% 32
8 PL QUANTUM MED ENGN 32900 0% 73% 11
9 PHARMACEUT MED CHEM 2 31309 0% 40% 19
10 NEUROBIOL PHARMACOL MOL 27530 0% 75% 9

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AGENTS AND ACTIONS 170940 5% 11% 367
2 INFLAMMATION RESEARCH 110880 4% 10% 276
3 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 8722 2% 2% 115
4 EUROPEAN JOURNAL OF PHARMACOLOGY 7939 3% 1% 239
5 BRITISH JOURNAL OF PHARMACOLOGY 7340 2% 1% 182
6 METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 6302 1% 2% 64
7 ARCHIV DER PHARMAZIE 5204 1% 2% 75
8 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 4701 2% 1% 160
9 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2767 2% 1% 136
10 NEUROPHARMACOLOGY 2514 1% 1% 78

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 HISTAMINE 1443238 19% 25% 1426 Search HISTAMINE Search HISTAMINE
2 HISTAMINE H 3 RECEPTOR 1152822 4% 93% 304 Search HISTAMINE+H+3+RECEPTOR Search HISTAMINE+H+3+RECEPTOR
3 THIOPERAMIDE 546532 2% 87% 154 Search THIOPERAMIDE Search THIOPERAMIDE
4 H 3 RECEPTOR 497949 2% 88% 138 Search H+3+RECEPTOR Search H+3+RECEPTOR
5 HISTAMINE H 1 RECEPTOR 374874 2% 58% 159 Search HISTAMINE+H+1+RECEPTOR Search HISTAMINE+H+1+RECEPTOR
6 HISTAMINE RECEPTORS 367680 2% 54% 168 Search HISTAMINE+RECEPTORS Search HISTAMINE+RECEPTORS
7 HISTAMINE H 4 RECEPTOR 293322 1% 90% 80 Search HISTAMINE+H+4+RECEPTOR Search HISTAMINE+H+4+RECEPTOR
8 R ALPHA METHYLHISTAMINE 253000 1% 89% 70 Search R+ALPHA+METHYLHISTAMINE Search R+ALPHA+METHYLHISTAMINE
9 HISTIDINE DECARBOXYLASE 183437 2% 39% 116 Search HISTIDINE+DECARBOXYLASE Search HISTIDINE+DECARBOXYLASE
10 HISTAMINE N METHYLTRANSFERASE 168851 1% 84% 49 Search HISTAMINE+N+METHYLTRANSFERASE Search HISTAMINE+N+METHYLTRANSFERASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PANULA, P , CHAZOT, PL , COWART, M , GUTZMER, R , LEURS, R , LIU, WLS , HAAS, HL , THURMOND, RL , STARK, H , (2015) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. XCVIII. HISTAMINE RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 67. ISSUE 3. P. 601 -655 471 78% 26
2 HAAS, HL , SERGEEVA, OA , SELBACH, O , (2008) HISTAMINE IN THE NERVOUS SYSTEM.PHYSIOLOGICAL REVIEWS. VOL. 88. ISSUE 3. P. 1183-1241 475 62% 412
3 BROWN, RE , STEVENS, DR , HAAS, HL , (2001) THE PHYSIOLOGY OF BRAIN HISTAMINE.PROGRESS IN NEUROBIOLOGY. VOL. 63. ISSUE 6. P. 637 -672 281 78% 594
4 SADEK, B , STARK, H , (2016) CHERRY-PICKED LIGANDS AT HISTAMINE RECEPTOR SUBTYPES.NEUROPHARMACOLOGY. VOL. 106. ISSUE . P. 56 -73 176 85% 6
5 SCHWARTZ, JC , ARRANG, JM , GARBARG, M , POLLARD, H , RUAT, M , (1991) HISTAMINERGIC TRANSMISSION IN THE MAMMALIAN BRAIN.PHYSIOLOGICAL REVIEWS. VOL. 71. ISSUE 1. P. 1 -51 319 69% 780
6 BERLIN, M , BOYCE, CW , RUIZ, MD , (2011) HISTAMINE H-3 RECEPTOR AS A DRUG DISCOVERY TARGET.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 54. ISSUE 1. P. 26 -53 188 82% 69
7 NIETO-ALAMILLA, G , MARQUEZ-GOMEZ, R , GARCIA-GALVEZ, AM , MORALES-FIGUEROA, GE , ARIAS-MONTANO, JA , (2016) THE HISTAMINE H-3 RECEPTOR: STRUCTURE, PHARMACOLOGY, AND FUNCTION.MOLECULAR PHARMACOLOGY. VOL. 90. ISSUE 5. P. 649 -673 193 79% 1
8 SANDER, K , KOTTKE, T , STARK, H , (2008) HISTAMINE H-3 RECEPTOR ANTAGONISTS GO TO CLINICS.BIOLOGICAL & PHARMACEUTICAL BULLETIN. VOL. 31. ISSUE 12. P. 2163 -2181 192 82% 101
9 HILL, SJ , GANELLIN, CR , TIMMERMAN, H , SCHWARTZ, JC , SHANKLEY, NP , YOUNG, JM , SCHUNACK, W , LEVI, R , HAAS, HL , (1997) INTERNATIONAL UNION OF PHARMACOLOGY .13. CLASSIFICATION OF HISTAMINE RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 49. ISSUE 3. P. 253 -278 198 73% 591
10 SADEK, B , SAAD, A , SADEQ, A , JALAL, F , STARK, H , (2016) HISTAMINE H3 RECEPTOR AS A POTENTIAL TARGET FOR COGNITIVE SYMPTOMS IN NEUROPSYCHIATRIC DISEASES.BEHAVIOURAL BRAIN RESEARCH. VOL. 312. ISSUE . P. 415 -430 157 82% 2

Classes with closest relation at Level 2


Rank Class id link
1 3951 NEFOPAM//ACRIVASTINE//METHAPYRILENE
2 1331 ALLERGIC RHINITIS//ANTIHISTAMINES//ALLERGIC CONJUNCTIVITIS
3 775 MAST CELLS//MASTOCYTOSIS//CHYMASE
4 3075 BIOGENIC AMINES//TYRAMINE//HISTAMINE FORMING BACTERIA
5 590 GASTRIC ULCER//GASTROPROTECTION//SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
6 705 G PROTEIN COUPLED RECEPTOR//GPCR//RHODOPSIN
7 2410 ARTICAINE//INFERIOR ALVEOLAR NERVE BLOCK//TOURNIQUET
8 1171 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM
9 3536 EVOLUTIONARY IMMUNOBIOL//PERITONEAL INFLAMMATION//ZYMOSAN
10 3057 CHRONIC URTICARIA//URTICARIA//CHRONIC IDIOPATHIC URTICARIA

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