Class information for:
Level 1: HISTAMINE H 1 RECEPTOR//MOL STUDIES INCURABLE DIS//H 3 MEPYRAMINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
24946 296 25.4 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
686 3       HISTAMINE//HISTAMINE H 3 RECEPTOR//THIOPERAMIDE 8239
1522 2             HISTAMINE//HISTAMINE H 3 RECEPTOR//THIOPERAMIDE 7482
24946 1                   HISTAMINE H 1 RECEPTOR//MOL STUDIES INCURABLE DIS//H 3 MEPYRAMINE 296

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HISTAMINE H 1 RECEPTOR authKW 1218693 19% 21% 57
2 MOL STUDIES INCURABLE DIS address 561643 2% 78% 7
3 H 3 MEPYRAMINE authKW 507856 3% 62% 8
4 HISTAMINE SIGNALING authKW 412638 1% 100% 4
5 ALLERGIC DISEASE SENSITIVE GENE authKW 206319 1% 100% 2
6 HISTAMINE H 1 RECEPTOR GENE authKW 206319 1% 100% 2
7 HISTAMINE H 1 RECEPTOR GENE TRANSCRIPTION authKW 206319 1% 100% 2
8 HISTAMINE RECEPTOR 1 ANTAGONIST authKW 206319 1% 100% 2
9 KUJIN authKW 206319 1% 100% 2
10 TEMELASTINE authKW 206319 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 2023 48% 0% 143
2 Otorhinolaryngology 1624 16% 0% 47
3 Allergy 138 3% 0% 10
4 Immunology 77 9% 0% 28
5 Biochemistry & Molecular Biology 54 16% 0% 46
6 Cell Biology 25 7% 0% 20
7 Biophysics 19 4% 0% 12
8 CYTOLOGY & HISTOLOGY 12 0% 0% 1
9 Anatomy & Morphology 11 1% 0% 3
10 Physiology 10 3% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL STUDIES INCURABLE DIS 561643 2% 78% 7
2 BIOMED SCIFUJII MEM MED SCI 103160 0% 100% 1
3 INTEGRATED BASCI MED SCI 103160 0% 100% 1
4 MED PHARMACOL 2 22 YAMADAOKA 103160 0% 100% 1
5 MED PHYSIOL PHARMACOL CLIFTON BLVD 103160 0% 100% 1
6 PHARMACOCHEM AMSTERDAM DRUG 103160 0% 100% 1
7 SUNFIELD STEM CELL PROC 103160 0% 100% 1
8 PARMACOGNOSY 82525 1% 40% 2
9 INTEGRATED BASIC MED SCI 68766 1% 17% 4
10 MOL MED SCIMINAMI KU 66312 1% 21% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF PHARMACOLOGICAL SCIENCES 9962 5% 1% 15
2 AGENTS AND ACTIONS 6287 5% 0% 14
3 EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION 6160 3% 1% 8
4 BRITISH JOURNAL OF PHARMACOLOGY 3622 8% 0% 25
5 ACTA OTO-LARYNGOLOGICA 3306 6% 0% 17
6 INFLAMMATION RESEARCH 2350 3% 0% 8
7 EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY 1135 3% 0% 8
8 INTERNATIONAL IMMUNOPHARMACOLOGY 850 2% 0% 6
9 MOLECULAR PHARMACOLOGY 844 3% 0% 9
10 IUGOSLAVICA PHYSIOLOGICA ET PHARMACOLOGICA ACTA 843 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HISTAMINE H 1 RECEPTOR 1218693 19% 21% 57 Search HISTAMINE+H+1+RECEPTOR Search HISTAMINE+H+1+RECEPTOR
2 H 3 MEPYRAMINE 507856 3% 62% 8 Search H+3+MEPYRAMINE Search H+3+MEPYRAMINE
3 HISTAMINE SIGNALING 412638 1% 100% 4 Search HISTAMINE+SIGNALING Search HISTAMINE+SIGNALING
4 ALLERGIC DISEASE SENSITIVE GENE 206319 1% 100% 2 Search ALLERGIC+DISEASE+SENSITIVE+GENE Search ALLERGIC+DISEASE+SENSITIVE+GENE
5 HISTAMINE H 1 RECEPTOR GENE 206319 1% 100% 2 Search HISTAMINE+H+1+RECEPTOR+GENE Search HISTAMINE+H+1+RECEPTOR+GENE
6 HISTAMINE H 1 RECEPTOR GENE TRANSCRIPTION 206319 1% 100% 2 Search HISTAMINE+H+1+RECEPTOR+GENE+TRANSCRIPTION Search HISTAMINE+H+1+RECEPTOR+GENE+TRANSCRIPTION
7 HISTAMINE RECEPTOR 1 ANTAGONIST 206319 1% 100% 2 Search HISTAMINE+RECEPTOR+1+ANTAGONIST Search HISTAMINE+RECEPTOR+1+ANTAGONIST
8 KUJIN 206319 1% 100% 2 Search KUJIN Search KUJIN
9 TEMELASTINE 206319 1% 100% 2 Search TEMELASTINE Search TEMELASTINE
10 U373 MG ASTROCYTOMA CELLS 154736 1% 50% 3 Search U373+MG+ASTROCYTOMA+CELLS Search U373+MG+ASTROCYTOMA+CELLS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KITAMURA, Y , NAKAGAWA, H , FUJII, T , SAKODA, T , ENOMOTO, T , MIZUGUCHI, H , FUKUI, H , TAKEDA, N , (2015) EFFECTS OF ANTIHISTAMINE ON UP-REGULATION OF HISTAMINE H-1 RECEPTOR MRNA IN THE NASAL MUCOSA OF PATIENTS WITH POLLINOSIS INDUCED BY CONTROLLED CEDAR POLLEN CHALLENGE IN AN ENVIRONMENTAL EXPOSURE UNIT.JOURNAL OF PHARMACOLOGICAL SCIENCES. VOL. 129. ISSUE 3. P. 183 -187 14 74% 0
2 MIYOSHI, K , DAS, AK , FUJIMOTO, K , HORIO, S , FUKUI, H , (2006) RECENT ADVANCES IN MOLECULAR PHARMACOLOGY OF THE HISTAMINE SYSTEMS: REGULATION OF HISTAMINE H-1 RECEPTOR SIGNALING BY CHANGING ITS EXPRESSION LEVEL.JOURNAL OF PHARMACOLOGICAL SCIENCES. VOL. 101. ISSUE 1. P. 3-6 12 100% 6
3 SHILL, MC , MIZUGUCHI, H , KARMAKAR, S , KADOTA, T , MUKHERJEE, PK , KITAMURA, Y , KASHIWADA, Y , NEMOTO, H , TAKEDA, N , FUKUI, H , (2016) A NOVEL BENZOFURAN, 4-METHOXYBENZOFURAN-5-CARBOXAMIDE, FROM TEPHROSIA PURPUREA SUPPRESSED HISTAMINE H-1 RECEPTOR GENE EXPRESSION THROUGH A PROTEIN KINASE C-DELTA-DEPENDENT SIGNALING PATHWAY.INTERNATIONAL IMMUNOPHARMACOLOGY. VOL. 30. ISSUE . P. 18 -26 17 44% 1
4 MIZUGUCHI, H , KITAMURA, Y , KONDO, Y , KURODA, W , YOSHIDA, H , MIYAMOTO, Y , HATTORI, M , TAKEDA, N , FUKUI, H , (2011) HISTAMINE H-1 RECEPTOR GENE AS AN ALLERGIC DISEASES-SENSITIVE GENE AND ITS IMPACT ON THERAPEUTICS FOR ALLERGIC DISEASES.YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN. VOL. 131. ISSUE 2. P. 171 -178 8 89% 1
5 MIZUGUCHI, H , ONO, S , HATTORI, M , SASAKI, Y , FUKUI, H , (2013) USEFULNESS OF HELA CELLS TO EVALUATE INVERSE AGONISTIC ACTIVITY OF ANTIHISTAMINES.INTERNATIONAL IMMUNOPHARMACOLOGY. VOL. 15. ISSUE 3. P. 539-543 10 63% 1
6 MIZUGUCHI, H , ONO, S , HATTORI, M , FUKUI, H , (2012) INVERSE AGONISTIC ACTIVITY OF ANTIHISTAMINES AND SUPPRESSION OF HISTAMINE H-1 RECEPTOR GENE EXPRESSION.JOURNAL OF PHARMACOLOGICAL SCIENCES. VOL. 118. ISSUE 1. P. 117-121 9 69% 3
7 MIYOSHI, K , KAWAKAMI, N , UMEHARA, H , FUJIMOTO, K , HORIO, S , FUKUI, H , (2008) DOWN-REGULATION OF HISTAMINE H-1 RECEPTORS BY BETA(2)-ADRENOCEPTOR-MEDIATED INHIBITION OF H-1 RECEPTOR GENE TRANSCRIPTION.JOURNAL OF PHARMACY AND PHARMACOLOGY. VOL. 60. ISSUE 6. P. 747-752 12 55% 1
8 HATTORI, M , MIZUGUCHI, H , BABA, Y , ONO, S , NAKANO, T , ZHANG, Q , SASAKI, Y , KOBAYASHI, M , KITAMURA, Y , TAKEDA, N , ET AL (2013) QUERCETIN INHIBITS TRANSCRIPTIONAL UP-REGULATION OF HISTAMINE H-1 RECEPTOR VIA SUPPRESSING PROTEIN KINASE C-DELTA/EXTRACELLULAR SIGNAL-REGULATED KINASE/POLY(ADP-RIBOSE) POLYMERASE-1 SIGNALING PATHWAY IN HELA CELLS.INTERNATIONAL IMMUNOPHARMACOLOGY. VOL. 15. ISSUE 2. P. 232-239 14 40% 0
9 KITAMURA, Y , MIYOSHI, A , MURATA, Y , KALUBI, B , FUKUI, H , TAKEDA, N , (2004) EFFECT OF GLUCOCORTICOID ON UPREGULATION OF HISTAMINE H-1 RECEPTOR MRNA IN NASAL MUCOSA OF RATS SENSITIZED BY EXPOSURE TO TOLUENE DIISOCYANATE.ACTA OTO-LARYNGOLOGICA. VOL. 124. ISSUE 9. P. 1053-1058 10 67% 30
10 HORIO, S , FUJIMOTO, K , MIZUGUCHI, H , FUKUI, H , (2010) INTERLEUKIN-4 UP-REGULATES HISTAMINE H1 RECEPTORS BY ACTIVATION OF H1 RECEPTOR GENE TRANSCRIPTION.NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. VOL. 381. ISSUE 4. P. 305 -313 12 43% 7

Classes with closest relation at Level 1


Rank Class id link
1 4836 HISTAMINE H 4 RECEPTOR//HISTAMINE//JNJ7777120
2 960 HISTAMINE H 3 RECEPTOR//THIOPERAMIDE//H 3 RECEPTOR
3 11769 HISTAMINE H 2 RECEPTORS//CAS 76963 41 2//AGENTS AND ACTIONS
4 34415 SUPLATAST TOSILATE//CX 659S//TH2 TYPE REACTION
5 11603 BRAIN CORTICAL SLICES//PHOSPHOINOSITIDE BREAKDOWN//CMP PHOSPHATIDATE
6 28878 ANTIFERTIL INFERTIL//OVARIAN MAST CELLS//UTERINE MAST CELL
7 9635 PROPRANOLOL INDUCED BRONCHOCONSTRICTION//MUSCARINIC AUTORECEPTORS//BETA ADRENOCEPTOR MEDIATED RELAXATION
8 26532 AGONIST AFFINITY//ANTAGONIST DISSOCIATION CONSTANTS//IRREVERSIBLE RECEPTOR INACTIVATION METHOD
9 7382 JOURNAL OF CYCLIC NUCLEOTIDE RESEARCH//JOURNAL OF CYCLIC NUCLEOTIDE AND PROTEIN PHOSPHORYLATION RESEARCH//JOURNAL OF RECEPTOR RESEARCH
10 7416 ACOUSTIC RHINOMETRY//RHINOMANOMETRY//NASAL PATENCY

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