Class information for:
Level 2: SOLID PHASE SYNTHESIS//JOURNAL OF COMBINATORIAL CHEMISTRY//NATIVE CHEMICAL LIGATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1347 8307 32.5 66%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
534 3       PYRIMIDINOPHANES//SOLID PHASE SYNTHESIS//INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 19564
1347 2             SOLID PHASE SYNTHESIS//JOURNAL OF COMBINATORIAL CHEMISTRY//NATIVE CHEMICAL LIGATION 8307
728 1                   JOURNAL OF COMBINATORIAL CHEMISTRY//SOLID PHASE SYNTHESIS//COMBINATORIAL CHEMISTRY 3128
5605 1                   NATIVE CHEMICAL LIGATION//PEPTIDE THIOESTER//DIFFICULT SEQUENCE 1598
6167 1                   INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH//PHARMACEUT SCI SAKYO KU//MED SAKYO KU 1519
13640 1                   COUPLING REAGENTS//RACEMIZATION FREE COUPLING//PEPTIDE COUPLING REAGENTS 823
24642 1                   2 OXAZOLONE//2 THIAZOLONE//1 3 DIHYDRO 2 IMIDAZOLONE 305
26683 1                   HETEROCYCL CPDS//N ACYLSULFONAMIDE//N ACYLBENZOTRIAZOLES 248
26904 1                   N N ALKYLIDENE BISAMIDES//RETRO PROTEIN//BISAMIDES 242
27705 1                   ACYL AZIDE//UREIDOPEPTIDES//CARBAMOYL AZIDES 223
31243 1                   BISO NITROPHENYL CARBONATE//TRIPHOSGENE//PETR TEHNOL 156
37144 1                   TOYOPEARL HW//BONE SCIENTIGRAPHY//D SERINE UTILIZATION 65

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SOLID PHASE SYNTHESIS authKW 392632 6% 22% 498
2 JOURNAL OF COMBINATORIAL CHEMISTRY journal 392495 5% 28% 382
3 NATIVE CHEMICAL LIGATION authKW 374209 2% 61% 168
4 SOLID PHASE PEPTIDE SYNTHESIS authKW 251117 3% 32% 213
5 COMBINATORIAL CHEMISTRY authKW 208319 4% 18% 308
6 PEPTIDE THIOESTER authKW 190865 1% 88% 59
7 INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH journal 135278 4% 12% 304
8 DIFFICULT SEQUENCE authKW 121079 0% 80% 41
9 SOLID PHASE ORGANIC SYNTHESIS authKW 97252 1% 46% 58
10 PEPTIDE SYNTHESIS authKW 90658 2% 16% 157

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Chemistry, Organic 72417 42% 1% 3509
2 Chemistry, Multidisciplinary 15846 30% 0% 2463
3 Chemistry, Medicinal 14778 13% 0% 1084
4 Chemistry, Applied 5242 8% 0% 677
5 Biochemistry & Molecular Biology 3389 21% 0% 1704
6 Biochemical Research Methods 1077 5% 0% 394
7 Chemistry, Analytical 363 4% 0% 367
8 Biophysics 186 3% 0% 240
9 Pharmacology & Pharmacy 135 5% 0% 433
10 Polymer Science 42 2% 0% 179

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HETEROCYCL CPDS 80981 1% 20% 113
2 PHARMACEUT SCI SAKYO KU 41381 1% 21% 55
3 MED SAKYO KU 31336 0% 53% 16
4 21ST CENTURY COE PROGRAMYAMASHINA KU 28256 0% 77% 10
5 UMR CNRS 8161 22954 0% 63% 10
6 PEPTIDE 22400 0% 17% 36
7 BARCELONA BIOMED 18767 0% 34% 15
8 COMBINATORIAL EXCELLENCE 18767 0% 34% 15
9 ARTCHEM 18370 0% 100% 5
10 NOVABIOCHEM 16361 0% 64% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 JOURNAL OF COMBINATORIAL CHEMISTRY 392495 5% 28% 382
2 INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 135278 4% 12% 304
3 JOURNAL OF PEPTIDE SCIENCE 78994 2% 11% 197
4 TETRAHEDRON LETTERS 77335 15% 2% 1244
5 PEPTIDE RESEARCH 54173 1% 26% 57
6 LETTERS IN PEPTIDE SCIENCE 33202 1% 14% 67
7 MOLECULAR DIVERSITY 28809 1% 9% 87
8 JOURNAL OF PEPTIDE RESEARCH 24887 1% 9% 79
9 INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS 12501 1% 8% 43
10 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 9823 1% 5% 60

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SOLID PHASE SYNTHESIS 392632 6% 22% 498 Search SOLID+PHASE+SYNTHESIS Search SOLID+PHASE+SYNTHESIS
2 NATIVE CHEMICAL LIGATION 374209 2% 61% 168 Search NATIVE+CHEMICAL+LIGATION Search NATIVE+CHEMICAL+LIGATION
3 SOLID PHASE PEPTIDE SYNTHESIS 251117 3% 32% 213 Search SOLID+PHASE+PEPTIDE+SYNTHESIS Search SOLID+PHASE+PEPTIDE+SYNTHESIS
4 COMBINATORIAL CHEMISTRY 208319 4% 18% 308 Search COMBINATORIAL+CHEMISTRY Search COMBINATORIAL+CHEMISTRY
5 PEPTIDE THIOESTER 190865 1% 88% 59 Search PEPTIDE+THIOESTER Search PEPTIDE+THIOESTER
6 DIFFICULT SEQUENCE 121079 0% 80% 41 Search DIFFICULT+SEQUENCE Search DIFFICULT+SEQUENCE
7 SOLID PHASE ORGANIC SYNTHESIS 97252 1% 46% 58 Search SOLID+PHASE+ORGANIC+SYNTHESIS Search SOLID+PHASE+ORGANIC+SYNTHESIS
8 PEPTIDE SYNTHESIS 90658 2% 16% 157 Search PEPTIDE+SYNTHESIS Search PEPTIDE+SYNTHESIS
9 COUPLING REAGENTS 87614 1% 47% 51 Search COUPLING+REAGENTS Search COUPLING+REAGENTS
10 CHEMICAL LIGATION 60599 1% 38% 43 Search CHEMICAL+LIGATION Search CHEMICAL+LIGATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GUILLIER, F , ORAIN, D , BRADLEY, M , (2000) LINKERS AND CLEAVAGE STRATEGIES IN SOLID-PHASE ORGANIC SYNTHESIS AND COMBINATORIAL CHEMISTRY.CHEMICAL REVIEWS. VOL. 100. ISSUE 6. P. 2091 -2157 327 74% 447
2 EL-FAHAM, A , ALBERICIO, F , (2011) PEPTIDE COUPLING REAGENTS, MORE THAN A LETTER SOUP.CHEMICAL REVIEWS. VOL. 111. ISSUE 11. P. 6557 -6602 158 76% 232
3 FIELDS, GB , NOBLE, RL , (1990) SOLID-PHASE PEPTIDE-SYNTHESIS UTILIZING 9-FLUORENYLMETHOXYCARBONYL AMINO-ACIDS.INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH. VOL. 35. ISSUE 3. P. 161-214 188 72% 1991
4 ISIDRO-LLOBET, A , ALVAREZ, M , ALBERICIO, F , (2009) AMINO ACID-PROTECTING GROUPS.CHEMICAL REVIEWS. VOL. 109. ISSUE 6. P. 2455-2504 196 69% 186
5 JAMES, IW , (1999) LINKERS FOR SOLID PHASE ORGANIC SYNTHESIS.TETRAHEDRON. VOL. 55. ISSUE 16. P. 4855 -4946 256 71% 246
6 LAM, KS , LEBL, M , KRCHNAK, V , (1997) THE ''ONE-BEAD-ONE-COMPOUND'' COMBINATORIAL LIBRARY METHOD.CHEMICAL REVIEWS. VOL. 97. ISSUE 2. P. 411-448 195 70% 544
7 BONDALAPATI, S , JBARA, M , BRIK, A , (2016) EXPANDING THE CHEMICAL TOOLBOX FOR THE SYNTHESIS OF LARGE AND UNIQUELY MODIFIED PROTEINS.NATURE CHEMISTRY. VOL. 8. ISSUE 5. P. 407 -418 80 79% 18
8 MONBALIU, JCM , KATRITZKY, AR , (2012) RECENT TRENDS IN CYS- AND SER/THR-BASED SYNTHETIC STRATEGIES FOR THE ELABORATION OF PEPTIDE CONSTRUCTS.CHEMICAL COMMUNICATIONS. VOL. 48. ISSUE 95. P. 11601 -11622 165 75% 15
9 GUAN, XY , CHAFFEY, PK , ZENG, C , TAN, ZP , (2015) NEW METHODS FOR CHEMICAL PROTEIN SYNTHESIS.PROTEIN LIGATION AND TOTAL SYNTHESIS II. VOL. 363. ISSUE . P. 155 -192 138 85% 2
10 BEHRENDT, R , WHITE, P , OFFER, J , (2016) ADVANCES IN FMOC SOLID-PHASE PEPTIDE SYNTHESIS.JOURNAL OF PEPTIDE SCIENCE. VOL. 22. ISSUE 1. P. 4 -27 140 59% 6

Classes with closest relation at Level 2


Rank Class id link
1 4012 N PHOSPHORYL AMINO ACID//BIOORGAN PHOSPHORUS CHEM//PHOSPHOPEPTIDE SYNTHESIS
2 1200 PEPTAIBOL//FOLDAMERS//PEPTOIDS
3 3851 GUANIDINE//ANGIPARS TM//SEMELIL
4 2525 PROTEIN MICROARRAY//DIAZIRINE//PROTEIN ARRAY
5 2695 PHASE TRANSFER CATALYSIS//TRIPHASE CATALYSIS//THIRD LIQUID PHASE
6 3929 TRIVALINE//POLYNUCLEOTIDE ANALOGUE//ADENOSINE IMMOBILIZED SILICA
7 1215 DEPROTECTION//1 1 DIACETATES//EPOXIDES
8 3445 HYDANTOIN//PYOCYANIN//THIOHYDANTOIN
9 1537 CELL FREE PROTEIN SYNTHESIS//INTEIN//PROTEIN SPLICING
10 3468 METALLACROWN//AMINOHYDROXAMIC ACIDS//HYDROXAMIC ACID

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