Class information for:
Level 2: HEME OXYGENASE//PORPHYRIA//HEME OXYGENASE 1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1296 8624 39.2 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
468 3       GLUCOSINOLATES//BILIRUBIN//HEME OXYGENASE 24157
1296 2             HEME OXYGENASE//PORPHYRIA//HEME OXYGENASE 1 8624
339 1                   HEME OXYGENASE//HEME OXYGENASE 1//CARBON MONOXIDE 3623
2758 1                   ACUTE INTERMITTENT PORPHYRIA//PORPHYRIA//ERYTHROPOIETIC PROTOPORPHYRIA 2156
6691 1                   PORPHYRIA CUTANEA TARDA//UROPORPHYRINOGEN DECARBOXYLASE//PORPHYRIA 1455
16240 1                   X LINKED SIDEROBLASTIC ANEMIA//ALAS2//5 AMINOLEVULINATE SYNTHASE 665
21839 1                   SN MESOPORPHYRIN//HEME OXYGENASE INHIBITOR//TIN MESOPORPHYRIN 403
24135 1                   HEMOPEXIN//WAP65//RABBIT HEMOPEXIN 322

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEME OXYGENASE authKW 1257360 8% 50% 708
2 PORPHYRIA authKW 777168 3% 73% 299
3 HEME OXYGENASE 1 authKW 668753 7% 32% 598
4 ACUTE INTERMITTENT PORPHYRIA authKW 546304 2% 91% 169
5 PORPHYRIA CUTANEA TARDA authKW 448377 2% 80% 158
6 ERYTHROPOIETIC PROTOPORPHYRIA authKW 310396 1% 88% 100
7 CARBON MONOXIDE authKW 272665 8% 11% 676
8 FERROCHELATASE authKW 237455 1% 62% 109
9 FRANCAIS PORPHYRIES address 177964 1% 77% 65
10 UROPORPHYRINOGEN DECARBOXYLASE authKW 175549 1% 81% 61

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 6053 25% 0% 2172
2 Dermatology 4988 6% 0% 539
3 Medicine, Research & Experimental 2326 7% 0% 624
4 Medical Laboratory Technology 1906 3% 0% 234
5 Hematology 1868 5% 0% 455
6 Pharmacology & Pharmacy 1431 10% 0% 868
7 Gastroenterology & Hepatology 1135 4% 0% 368
8 Cell Biology 1007 8% 0% 654
9 Physiology 990 5% 0% 405
10 Biophysics 985 5% 0% 429

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FRANCAIS PORPHYRIES 177964 1% 77% 65
2 PORPHYRIA SWEDEN 97158 0% 89% 31
3 VASC BIOL UNIT 60968 1% 21% 83
4 PORPHYRIA 52110 0% 82% 18
5 NEONATAL PHYSIOL 34930 0% 45% 22
6 MOL BIOL PL PHYSIOL 30801 0% 24% 37
7 BIOCHEM MOL GENET UNIT 28310 0% 100% 8
8 EUREG PORPHYRIA MAASTRICHT 28310 0% 100% 8
9 PORFIRIAS EXPT METAB HEMO 28310 0% 100% 8
10 BIOCHEM HEMATOL 27158 0% 40% 19

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANTIOXIDANTS & REDOX SIGNALING 9780 1% 3% 93
2 CELLULAR AND MOLECULAR BIOLOGY 8670 1% 3% 89
3 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 6794 1% 3% 77
4 BIOCHEMICAL PHARMACOLOGY 2464 1% 1% 118
5 PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE 2055 0% 2% 27
6 FREE RADICAL BIOLOGY AND MEDICINE 1951 1% 1% 71
7 SEMINARS IN DERMATOLOGY 1630 0% 3% 15
8 BIOCHEMICAL JOURNAL 1624 1% 0% 123
9 CLINICS IN HAEMATOLOGY 1589 0% 4% 11
10 EXPERIMENTAL BIOLOGY AND MEDICINE 1587 0% 1% 35

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HEME OXYGENASE 1257360 8% 50% 708 Search HEME+OXYGENASE Search HEME+OXYGENASE
2 PORPHYRIA 777168 3% 73% 299 Search PORPHYRIA Search PORPHYRIA
3 HEME OXYGENASE 1 668753 7% 32% 598 Search HEME+OXYGENASE+1 Search HEME+OXYGENASE+1
4 ACUTE INTERMITTENT PORPHYRIA 546304 2% 91% 169 Search ACUTE+INTERMITTENT+PORPHYRIA Search ACUTE+INTERMITTENT+PORPHYRIA
5 PORPHYRIA CUTANEA TARDA 448377 2% 80% 158 Search PORPHYRIA+CUTANEA+TARDA Search PORPHYRIA+CUTANEA+TARDA
6 ERYTHROPOIETIC PROTOPORPHYRIA 310396 1% 88% 100 Search ERYTHROPOIETIC+PROTOPORPHYRIA Search ERYTHROPOIETIC+PROTOPORPHYRIA
7 CARBON MONOXIDE 272665 8% 11% 676 Search CARBON+MONOXIDE Search CARBON+MONOXIDE
8 FERROCHELATASE 237455 1% 62% 109 Search FERROCHELATASE Search FERROCHELATASE
9 UROPORPHYRINOGEN DECARBOXYLASE 175549 1% 81% 61 Search UROPORPHYRINOGEN+DECARBOXYLASE Search UROPORPHYRINOGEN+DECARBOXYLASE
10 VARIEGATE PORPHYRIA 163780 1% 86% 54 Search VARIEGATE+PORPHYRIA Search VARIEGATE+PORPHYRIA

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RYTER, SW , ALAM, J , CHOI, AMK , (2006) HEME OXYGENASE-1/CARBON MONOXIDE: FROM BASIC SCIENCE TO THERAPEUTIC APPLICATIONS.PHYSIOLOGICAL REVIEWS. VOL. 86. ISSUE 2. P. 583 -650 410 61% 1163
2 RYTER, SW , CHOI, AMK , (2016) TARGETING HEME OXYGENASE-1 AND CARBON MONOXIDE FOR THERAPEUTIC MODULATION OF INFLAMMATION.TRANSLATIONAL RESEARCH. VOL. 167. ISSUE 1. P. 7 -34 250 75% 13
3 ABRAHAM, NG , KAPPAS, A , (2008) PHARMACOLOGICAL AND CLINICAL ASPECTS OF HEME OXYGENASE.PHARMACOLOGICAL REVIEWS. VOL. 60. ISSUE 1. P. 79 -127 336 58% 508
4 WU, LY , WANG, R , (2005) CARBON MONOXIDE: ENDOGENOUS PRODUCTION, PHYSIOLOGICAL FUNCTIONS, AND PHARMACOLOGICAL APPLICATIONS.PHARMACOLOGICAL REVIEWS. VOL. 57. ISSUE 4. P. 585 -630 325 70% 380
5 LOBODA, A , JAZWA, A , GROCHOT-PRZECZEK, A , RUTKOWSKI, AJ , CISOWSKI, J , AGARWAL, A , JOZKOWICZ, A , DULAK, J , (2008) HEME OXYGENASE-1 AND THE VASCULAR BED: FROM MOLECULAR MECHANISMS TO THERAPEUTIC OPPORTUNITIES.ANTIOXIDANTS & REDOX SIGNALING. VOL. 10. ISSUE 10. P. 1767 -1812 311 69% 106
6 MOTTERLINI, R , OTTERBEIN, LE , (2010) THE THERAPEUTIC POTENTIAL OF CARBON MONOXIDE.NATURE REVIEWS DRUG DISCOVERY. VOL. 9. ISSUE 9. P. 728 -U24 148 88% 375
7 AYER, A , ZARJOU, A , AGARWAL, A , STOCKER, R , (2016) HEME OXYGENASES IN CARDIOVASCULAR HEALTH AND DISEASE.PHYSIOLOGICAL REVIEWS. VOL. 96. ISSUE 4. P. 1449 -1508 324 54% 1
8 OTTERBEIN, LE , FORESTI, R , MOTTERLINI, R , (2016) HEME OXYGENASE-1 AND CARBON MONOXIDE IN THE HEART THE BALANCING ACT BETWEEN DANGER SIGNALING AND PRO-SURVIVAL.CIRCULATION RESEARCH. VOL. 118. ISSUE 12. P. 1940 -1959 159 78% 2
9 ABRAHAM, NG , JUNGE, JM , DRUMMOND, GS , (2016) TRANSLATIONAL SIGNIFICANCE OF HEME OXYGENASE IN OBESITY AND METABOLIC SYNDROME.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 37. ISSUE 1. P. 17 -36 148 63% 6
10 NATH, KA , (2006) HEME OXYGENASE-1: A PROVENANCE FOR CYTOPROTECTIVE PATHWAYS IN THE KIDNEY AND OTHER TISSUES.KIDNEY INTERNATIONAL. VOL. 70. ISSUE 3. P. 432 -443 161 79% 172

Classes with closest relation at Level 2


Rank Class id link
1 2994 NRF2//KEAP1//ANTIOXIDANT RESPONSE ELEMENT
2 1434 BILIRUBIN//HYPERBILIRUBINEMIA//KERNICTERUS
3 3246 CARBON MONOXIDE POISONING//CARBOXYHEMOGLOBIN//CARBON MONOXIDE
4 4188 APPLIED KINESIOLOGY//BLOOD LEAD DETERMINATION//HEMATOLOGICAL AND CLINICOCHEMICAL PARAMETERS
5 2958 HYDROGEN SULFIDE//CYSTATHIONINE GAMMA LYASE//GASOTRANSMITTER
6 1324 PROTOCHLOROPHYLLIDE//CHLOROPHYLL BIOSYNTHESIS//PLASTID TRANSFORMATION
7 3990 HARDERIAN GLAND//MICROBIAL BIOTECHNOL CELL BIOL//FLUORESCENT UBIQUITINATION BASED CELL CYCLE INDICATOR FUCCI
8 210 IRON OVERLOAD//HEPCIDIN//HEMOCHROMATOSIS
9 2623 PHOTOPATCH TEST//PHOTOALLERGY//PHENOTHIAZINE
10 3543 ALKAPTONURIA//OCHRONOSIS//HOMOGENTISIC ACID

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