Class information for:
Level 1: SMAD//SMAD4//TGF BETA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1117 2843 51.9 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
27 3       DEVELOPMENTAL BIOLOGY//DEVELOPMENT//AGR2 109777
1072 2             TGF BETA//SMAD//ENDOGLIN 9938
1117 1                   SMAD//SMAD4//TGF BETA 2843

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SMAD authKW 740432 10% 24% 290
2 SMAD4 authKW 551003 5% 35% 147
3 TGF BETA authKW 470128 18% 9% 503
4 SMAD7 authKW 427286 4% 38% 105
5 SNON authKW 355066 1% 85% 39
6 SKI authKW 219593 2% 44% 47
7 DEV SIGNALLING address 215625 1% 57% 35
8 SMADS authKW 209179 3% 27% 72
9 SMAD2 authKW 208541 2% 29% 68
10 C SKI authKW 182137 1% 81% 21

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cell Biology 11744 33% 0% 952
2 Oncology 8259 29% 0% 822
3 Biochemistry & Molecular Biology 5473 38% 0% 1083
4 Developmental Biology 1233 5% 0% 129
5 Genetics & Heredity 883 9% 0% 246
6 Gastroenterology & Hepatology 285 4% 0% 109
7 Biophysics 253 5% 0% 129
8 Pathology 162 3% 0% 81
9 Medicine, Research & Experimental 128 4% 0% 106
10 Urology & Nephrology 33 2% 0% 51

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEV SIGNALLING 215625 1% 57% 35
2 FUTURE PROGRAM 140558 1% 55% 24
3 CELL REGULAT CARCINOGENESIS 127892 2% 19% 63
4 GI DEV BIOL 34362 0% 80% 4
5 MODELING BIOL NETWORKS 34362 0% 80% 4
6 CANC GENET DIGEST DIS DEV MOL BIOL 24542 0% 57% 4
7 CELLULAR BIOCHEM H3 24161 0% 75% 3
8 MED ONCOLCANC NEW JERSEY 24161 0% 75% 3
9 CHEM BIOLERNEST MARIO PHARM 21477 0% 100% 2
10 EARLY PHASE CLIN INVEST 21477 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYTOKINE & GROWTH FACTOR REVIEWS 8341 1% 3% 25
2 ONCOGENE 6792 4% 1% 108
3 JOURNAL OF BIOLOGICAL CHEMISTRY 4552 9% 0% 262
4 CANCER RESEARCH 4334 5% 0% 128
5 CELL AND BIOSCIENCE 1595 0% 2% 7
6 CELLULAR SIGNALLING 1497 1% 1% 25
7 GENES & DEVELOPMENT 1422 1% 0% 32
8 MOLECULAR CELL 1284 1% 0% 26
9 MOLECULAR AND CELLULAR BIOLOGY 1170 2% 0% 51
10 CELL RESEARCH 1091 0% 1% 12

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SMAD 740432 10% 24% 290 Search SMAD Search SMAD
2 SMAD4 551003 5% 35% 147 Search SMAD4 Search SMAD4
3 TGF BETA 470128 18% 9% 503 Search TGF+BETA Search TGF+BETA
4 SMAD7 427286 4% 38% 105 Search SMAD7 Search SMAD7
5 SNON 355066 1% 85% 39 Search SNON Search SNON
6 SKI 219593 2% 44% 47 Search SKI Search SKI
7 SMADS 209179 3% 27% 72 Search SMADS Search SMADS
8 SMAD2 208541 2% 29% 68 Search SMAD2 Search SMAD2
9 C SKI 182137 1% 81% 21 Search C+SKI Search C+SKI
10 DPC4 158415 1% 51% 29 Search DPC4 Search DPC4

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SHI, YG , MASSAGUE, J , (2003) MECHANISMS OF TGF-BETA SIGNALING FROM CELL MEMBRANE TO THE NUCLEUS.CELL. VOL. 113. ISSUE 6. P. 685 -700 96 72% 3115
2 MASSAGUE, J , SEOANE, J , WOTTON, D , (2005) SMAD TRANSCRIPTION FACTORS.GENES & DEVELOPMENT. VOL. 19. ISSUE 23. P. 2783-2810 140 56% 1281
3 PARDALI, K , MOUSTAKAS, A , (2007) ACTIONS OF TGF-BETA AS TUMOR SUPPRESSOR AND PRO-METASTATIC FACTOR IN HUMAN CANCER.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1775. ISSUE 1. P. 21-62 223 48% 315
4 BROWN, KA , PIETENPOL, JA , MOSES, HL , (2007) A TALE OF TWO PROTEINS: DIFFERENTIAL ROLES AND REGULATION OF SMAD2 AND SMAD3 IN TGF-BETA SIGNALING.JOURNAL OF CELLULAR BIOCHEMISTRY. VOL. 101. ISSUE 1. P. 9-33 147 73% 183
5 LIU, F , (2003) RECEPTOR-REGULATED SMADS IN TGF-BETA SIGNALING.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 8. ISSUE . P. S1280-S1303 200 77% 27
6 FENG, XH , DERYNCK, R , (2005) SPECIFICITY AND VERSATILITY IN TGF-BETA SIGNALING THROUGH SMADS.ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY. VOL. 21. ISSUE . P. 659 -693 117 60% 1005
7 TEN DIJKE, PT , GOUMANS, MJ , ITOH, F , ITOH, S , (2002) REGULATION OF CELL PROLIFERATION BY SMAD PROTEINS.JOURNAL OF CELLULAR PHYSIOLOGY. VOL. 191. ISSUE 1. P. 1 -16 155 71% 294
8 ITOH, S , ITOH, F , GOUMANS, MJ , TEN DIJKE, P , (2000) SIGNALING OF TRANSFORMING GROWTH FACTOR-BETA FAMILY MEMBERS THROUGH SMAD PROTEINS.EUROPEAN JOURNAL OF BIOCHEMISTRY. VOL. 267. ISSUE 24. P. 6954 -6967 133 82% 349
9 DERYNCK, R , ZHANG, YE , (2003) SMAD-DEPENDENT AND SMAD-INDEPENDENT PATHWAYS IN TGF-BETA FAMILY SIGNALLING.NATURE. VOL. 425. ISSUE 6958. P. 577-584 64 66% 2493
10 ROSS, S , HILL, CS , (2008) HOW THE SMADS REGULATE TRANSCRIPTION.INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. VOL. 40. ISSUE 3. P. 383 -408 121 65% 190

Classes with closest relation at Level 1


Rank Class id link
1 29076 MIIP//BETAGLYCAN//T BETA RIII
2 1881 TGF BETA RECEPTORS//TRANSFORMING GROWTH FACTOR BETA//TGF BETA
3 35392 RED FISIOPATOL ENFERMEDADES HEPAT//ANTI APOPTOTIC SIGNALLING//BIOQUIM BIOL MOL MIXTO
4 20882 TGFB1//T869C//TGFBR1
5 12726 BONE MORPHOGENETIC PROTEIN 9//BMP9//BONE MORPHOGENETIC PROTEIN
6 37247 CD109//SYF2//ANTIGEN CD109
7 22610 WWP1//WW DOMAIN//CKIP 1
8 21816 GFAP GENE PROMOTER//TGF BETA 1 TRANSGENIC MICE//PHENOTYPE INDUCTION
9 13162 TWISTED GASTRULATION//BRINKER//DPP
10 24524 ADVENTITIAL FIBROBLASTS//CAROTID ARTERY RESTENOSIS//ADVENTITIA

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