Class information for:
Level 2: STAT3//GP130//ONCOSTATIN M

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1051 10071 45.0 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
422 3       C REACTIVE PROTEIN//STAT3//HAPTOGLOBIN 28303
1051 2             STAT3//GP130//ONCOSTATIN M 10071
2728 1                   INTERLEUKIN 6 RECEPTOR//IL 6 RECEPTOR//GP130 2164
3696 1                   STAT1//STAT5//STAT 1929
4688 1                   ONCOSTATIN M//LEUKEMIA INHIBITORY FACTOR//CILIARY NEUROTROPHIC FACTOR 1743
5366 1                   STAT3//GRIM 19//STAT3 INHIBITOR 1633
7798 1                   SOCS1//SOCS//SOCS3 1326
13676 1                   TOFACITINIB//JAK3//JANUS KINASE 820
20517 1                   INTERLEUKIN 11//IL 11//RECOMBINANT HUMAN INTERLEUKIN 11 456

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STAT3 authKW 662801 8% 27% 801
2 GP130 authKW 352419 2% 52% 225
3 ONCOSTATIN M authKW 311552 2% 58% 178
4 LEUKEMIA INHIBITORY FACTOR authKW 266481 2% 41% 216
5 CILIARY NEUROTROPHIC FACTOR authKW 215322 2% 44% 162
6 SOCS authKW 184932 1% 52% 118
7 STAT authKW 174342 2% 29% 202
8 SOCS3 authKW 173437 1% 41% 141
9 SOCS1 authKW 164462 1% 52% 105
10 INTERLEUKIN 11 authKW 159811 1% 49% 108

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cell Biology 15718 21% 0% 2164
2 Immunology 14604 20% 0% 1966
3 Biochemistry & Molecular Biology 11415 31% 0% 3073
4 Oncology 9550 18% 0% 1768
5 Hematology 5866 8% 0% 814
6 Medicine, Research & Experimental 1601 6% 0% 590
7 Rheumatology 881 2% 0% 202
8 Biophysics 608 4% 0% 398
9 Endocrinology & Metabolism 541 4% 0% 415
10 Neurosciences 443 7% 0% 665

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COOPERAT CELLULAR GROWTH TORS 59881 0% 48% 41
2 MOL CELLULAR IMMUNOL 38698 1% 23% 56
3 MOL IMMUNOL INFLAMMAT BRANCH 27919 0% 22% 42
4 WALTER ELIZA HALL MED 20784 1% 7% 98
5 COLON MOL CELL BIOL 20767 0% 57% 12
6 SECT PATHOPHYSIOL 19265 0% 29% 22
7 CANC HAEMATOL 14909 0% 19% 26
8 SIGNALING GRP STAT5 12624 0% 83% 5
9 SIGNAL NETWORK 11891 0% 30% 13
10 GRP RECH CYTOKINES RECEPTEURS 11399 0% 47% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYTOKINE 18424 2% 4% 165
2 JOURNAL OF IMMUNOLOGY 7696 4% 1% 382
3 JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 7653 1% 3% 76
4 BLOOD 5957 3% 1% 269
5 JOURNAL OF BIOLOGICAL CHEMISTRY 5372 6% 0% 556
6 CYTOKINE & GROWTH FACTOR REVIEWS 4573 0% 4% 35
7 EUROPEAN CYTOKINE NETWORK 3926 0% 4% 36
8 ONCOGENE 3473 1% 1% 149
9 MOLECULAR AND CELLULAR BIOLOGY 2213 1% 1% 134
10 IMMUNITY 2119 0% 1% 50

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 STAT3 662801 8% 27% 801 Search STAT3 Search STAT3
2 GP130 352419 2% 52% 225 Search GP130 Search GP130
3 ONCOSTATIN M 311552 2% 58% 178 Search ONCOSTATIN+M Search ONCOSTATIN+M
4 LEUKEMIA INHIBITORY FACTOR 266481 2% 41% 216 Search LEUKEMIA+INHIBITORY+FACTOR Search LEUKEMIA+INHIBITORY+FACTOR
5 CILIARY NEUROTROPHIC FACTOR 215322 2% 44% 162 Search CILIARY+NEUROTROPHIC+FACTOR Search CILIARY+NEUROTROPHIC+FACTOR
6 SOCS 184932 1% 52% 118 Search SOCS Search SOCS
7 STAT 174342 2% 29% 202 Search STAT Search STAT
8 SOCS3 173437 1% 41% 141 Search SOCS3 Search SOCS3
9 SOCS1 164462 1% 52% 105 Search SOCS1 Search SOCS1
10 INTERLEUKIN 11 159811 1% 49% 108 Search INTERLEUKIN+11 Search INTERLEUKIN+11

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HEINRICH, PC , BEHRMANN, I , HAAN, S , HERMANNS, HM , MULLER-NEWEN, G , SCHAPER, F , (2003) PRINCIPLES OF INTERLEUKIN (IL)-6-TYPE CYTOKINE SIGNALLING AND ITS REGULATION.BIOCHEMICAL JOURNAL. VOL. 374. ISSUE . P. 1-20 176 69% 1511
2 KIU, H , NICHOLSON, SE , (2012) BIOLOGY AND SIGNIFICANCE OF THE JAK/STAT SIGNALLING PATHWAYS.GROWTH FACTORS. VOL. 30. ISSUE 2. P. 88 -106 193 64% 79
3 AUERNHAMMER, CJ , MELMED, S , (2000) LEUKEMIA-INHIBITORY FACTOR - NEUROIMMUNE MODULATOR OF ENDOCRINE FUNCTION.ENDOCRINE REVIEWS. VOL. 21. ISSUE 3. P. 313 -345 265 63% 154
4 CROKER, BA , KIU, H , NICHOLSON, SE , (2008) SOCS REGULATION OF THE JAK/STAT SIGNALLING PATHWAY.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 19. ISSUE 4. P. 414-422 117 89% 230
5 HEINRICH, PC , BEHRMANN, I , MULLER-NEWEN, G , SCHAPER, F , GRAEVE, L , (1998) INTERLEUKIN-6-TYPE CYTOKINE SIGNALLING THROUGH THE GP130/JAK/STAT PATHWAY.BIOCHEMICAL JOURNAL. VOL. 334. ISSUE . P. 297 -314 139 64% 1207
6 SCHAPER, F , ROSE-JOHN, S , (2015) INTERLEUKIN-6: BIOLOGY, SIGNALING AND STRATEGIES OF BLOCKADE.CYTOKINE & GROWTH FACTOR REVIEWS. VOL. 26. ISSUE 5. P. 475 -487 122 70% 28
7 TANIGUCHI, K , KARIN, M , (2014) IL-6 AND RELATED CYTOKINES AS THE CRITICAL LYNCHPINS BETWEEN INFLAMMATION AND CANCER.SEMINARS IN IMMUNOLOGY. VOL. 26. ISSUE 1. P. 54 -74 167 43% 99
8 SANTOS, CI , COSTA-PEREIRA, AP , (2011) SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION-FROM CYTOKINE SIGNALLING TO CANCER BIOLOGY.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1816. ISSUE 1. P. 38-49 165 73% 23
9 ALEXANDER, WS , HILTON, DJ , (2004) THE ROLE OF SUPPRESSORS OF CYTOKINE SIGNALING (SOCS) PROTEINS IN REGULATION OF THE IMMUNERESPONSE.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 22. ISSUE . P. 503-529 118 84% 454
10 SIVEEN, KS , SIKKA, S , SURANA, R , DAI, XY , ZHANG, JW , KUMAR, AP , TAN, BKH , SETHI, G , BISHAYEE, A , (2014) TARGETING THE STAT3 SIGNALING PATHWAY IN CANCER: ROLE OF SYNTHETIC AND NATURAL INHIBITORS.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1845. ISSUE 2. P. 136 -154 135 48% 105

Classes with closest relation at Level 2


Rank Class id link
1 1321 INTERLEUKIN 12//CD23//INTERLEUKIN 4
2 1852 INTERLEUKIN 1//INTERLEUKIN 1 RECEPTOR ANTAGONIST//POLYMORPHISM
3 1202 JOURNAL OF INTERFERON RESEARCH//INTERFERON//JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
4 4146 PIM KINASE//PIM 1//PIM 2
5 2046 ESSENTIAL THROMBOCYTHEMIA//POLYCYTHEMIA VERA//MYELOFIBROSIS
6 209 EXPERIMENTAL HEMATOLOGY//THROMBOPOIETIN//HEMATOLOGY
7 1133 INTERLEUKIN 18//IL 33//IL 18
8 1216 PU1//ETS 1//GATA 1
9 2683 NEUTROPHIL EXTRACELLULAR TRAPS//SEVERE CONGENITAL NEUTROPENIA//NETOSIS
10 2482 HAPTOGLOBIN//ALPHA1 ACID GLYCOPROTEIN//ACUTE PHASE PROTEINS

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