Class information for:
Level 1: INTERLEUKIN 6 RECEPTOR//IL 6 RECEPTOR//GP130

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2728 2164 40.4 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
422 3       C REACTIVE PROTEIN//STAT3//HAPTOGLOBIN 28303
1051 2             STAT3//GP130//ONCOSTATIN M 10071
2728 1                   INTERLEUKIN 6 RECEPTOR//IL 6 RECEPTOR//GP130 2164

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERLEUKIN 6 RECEPTOR authKW 359511 3% 42% 61
2 IL 6 RECEPTOR authKW 351577 2% 46% 54
3 GP130 authKW 330705 5% 23% 101
4 INTERLEUKIN 6 authKW 305041 19% 5% 419
5 SOLUBLE INTERLEUKIN 6 RECEPTOR authKW 232670 2% 45% 37
6 TRANS SIGNALING authKW 164167 1% 73% 16
7 SOLUBLE IL 6 RECEPTOR authKW 132360 1% 45% 21
8 HYPER IL 6 authKW 114280 0% 90% 9
9 IL 6 authKW 112457 9% 4% 204
10 IL 6R authKW 106669 1% 34% 22

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 10525 34% 0% 736
2 Hematology 4736 15% 0% 321
3 Cell Biology 1894 17% 0% 361
4 Biochemistry & Molecular Biology 1576 26% 0% 553
5 Oncology 1090 13% 0% 291
6 Medicine, Research & Experimental 985 9% 0% 195
7 Rheumatology 316 2% 0% 54
8 Biophysics 171 4% 0% 94
9 Pathology 72 2% 0% 51
10 Cell & Tissue Engineering 45 1% 0% 11

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT PATHOPHYSIOL 81838 1% 28% 21
2 MOL PL BIOL SCI 28218 0% 100% 2
3 JOINT PROT STRUCT 23897 0% 17% 10
4 BIOCHEM MOL BIOL 2 23443 1% 6% 26
5 CLIN PLICAT BIOL 20741 0% 29% 5
6 MED SCI 1 18798 0% 17% 8
7 ABT PATHOPHYSIOL 17566 0% 14% 9
8 COLON MOL CELL BIOL 16789 0% 24% 5
9 ABENA KU 14109 0% 100% 1
10 ANALYT IMMUNOL CHRON PATHOLALBERT BONNIOT 14109 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYTOKINE 9941 3% 1% 56
2 JOURNAL OF IMMUNOLOGY 3704 6% 0% 121
3 EUROPEAN CYTOKINE NETWORK 3643 1% 2% 16
4 BLOOD 3423 4% 0% 93
5 LYMPHOKINE AND CYTOKINE RESEARCH 2928 0% 3% 7
6 EUROPEAN JOURNAL OF IMMUNOLOGY 2609 2% 0% 50
7 BRITISH JOURNAL OF HAEMATOLOGY 2143 2% 0% 46
8 EXPERIMENTAL HEMATOLOGY 1892 1% 0% 28
9 RESEARCH IN IMMUNOLOGY 1877 1% 1% 11
10 LEUKEMIA & LYMPHOMA 1622 1% 0% 30

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INTERLEUKIN 6 RECEPTOR 359511 3% 42% 61 Search INTERLEUKIN+6+RECEPTOR Search INTERLEUKIN+6+RECEPTOR
2 IL 6 RECEPTOR 351577 2% 46% 54 Search IL+6+RECEPTOR Search IL+6+RECEPTOR
3 GP130 330705 5% 23% 101 Search GP130 Search GP130
4 INTERLEUKIN 6 305041 19% 5% 419 Search INTERLEUKIN+6 Search INTERLEUKIN+6
5 SOLUBLE INTERLEUKIN 6 RECEPTOR 232670 2% 45% 37 Search SOLUBLE+INTERLEUKIN+6+RECEPTOR Search SOLUBLE+INTERLEUKIN+6+RECEPTOR
6 TRANS SIGNALING 164167 1% 73% 16 Search TRANS+SIGNALING Search TRANS+SIGNALING
7 SOLUBLE IL 6 RECEPTOR 132360 1% 45% 21 Search SOLUBLE+IL+6+RECEPTOR Search SOLUBLE+IL+6+RECEPTOR
8 HYPER IL 6 114280 0% 90% 9 Search HYPER+IL+6 Search HYPER+IL+6
9 IL 6 112457 9% 4% 204 Search IL+6 Search IL+6
10 IL 6R 106669 1% 34% 22 Search IL+6R Search IL+6R

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SCHELLER, J , CHALARIS, A , SCHMIDT-ARRAS, D , ROSE-JOHN, S , (2011) THE PRO- AND ANTI-INFLAMMATORY PROPERTIES OF THE CYTOKINE INTERLEUKIN-6.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1813. ISSUE 5. P. 878 -888 75 56% 507
2 HEINRICH, PC , CASTELL, JV , ANDUS, T , (1990) INTERLEUKIN-6 AND THE ACUTE PHASE RESPONSE.BIOCHEMICAL JOURNAL. VOL. 265. ISSUE 3. P. 621-636 110 58% 1811
3 ROSE-JOHN, S , (2012) IL-6 TRANS-SIGNALING VIA THE SOLUBLE IL-6 RECEPTOR: IMPORTANCE FOR THE PRO-INFLAMMATORY ACTIVITIES OF IL-6.INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES. VOL. 8. ISSUE 9. P. 1237-1247 75 75% 121
4 AKIRA, S , TAGA, T , KISHIMOTO, T , (1993) INTERLEUKIN-6 IN BIOLOGY AND MEDICINE.ADVANCES IN IMMUNOLOGY, VOL 54. VOL. 54. ISSUE . P. 1-78 159 42% 961
5 SIMPSON, RJ , HAMMACHER, A , SMITH, DK , MATTHEWS, JM , WARD, LD , (1997) INTERLEUKIN-6: STRUCTURE-FUNCTION RELATIONSHIPS.PROTEIN SCIENCE. VOL. 6. ISSUE 5. P. 929-955 169 54% 183
6 SCHELLER, J , GARBERS, C , ROSE-JOHN, S , (2014) INTERLEUKIN-6: FROM BASIC BIOLOGY TO SELECTIVE BLOCKADE OF PRO-INFLAMMATORY ACTIVITIES.SEMINARS IN IMMUNOLOGY. VOL. 26. ISSUE 1. P. 2-12 78 66% 47
7 VANSNICK, J , (1990) INTERLEUKIN-6 - AN OVERVIEW.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 8. ISSUE . P. 253-278 90 70% 1334
8 HUNTER, CA , JONES, SA , (2015) IL-6 AS A KEYSTONE CYTOKINE IN HEALTH AND DISEASE.NATURE IMMUNOLOGY. VOL. 16. ISSUE 5. P. 448 -457 67 39% 119
9 WOLF, J , ROSE-JOHN, S , GARBERS, C , (2014) INTERLEUKIN-6 AND ITS RECEPTORS: A HIGHLY REGULATED AND DYNAMIC SYSTEM.CYTOKINE. VOL. 70. ISSUE 1. P. 11 -20 71 55% 57
10 LE, JM , VILCEK, J , (1989) INTERLEUKIN-6 - A MULTIFUNCTIONAL CYTOKINE REGULATING IMMUNE-REACTIONS AND THE ACUTE PHASE PROTEIN RESPONSE.LABORATORY INVESTIGATION. VOL. 61. ISSUE 6. P. 588-602 114 66% 459

Classes with closest relation at Level 1


Rank Class id link
1 20921 BASAL CELL CARCINOMA CELLS//NIJMEGEN MOL LIFE SCI 278//SILTUXIMAB
2 20517 INTERLEUKIN 11//IL 11//RECOMBINANT HUMAN INTERLEUKIN 11
3 4688 ONCOSTATIN M//LEUKEMIA INHIBITORY FACTOR//CILIARY NEUROTROPHIC FACTOR
4 17299 174G C//INTERLEUKIN 6//INTERLEUKIN 6 POLYMORPHISM
5 19272 LIVER MICRO UNIT ACTION//ALPHA2 MACROGLOBULIN GENE//090
6 26623 PRISTANE//PLASMACYTOMAGENESIS//ABL MYC
7 37475 ANTIBODY VARIABLE REGION//TRANSGENE SELECTION//COMMUNICATION DISTANCE
8 24270 INTERFERON ANTIBODIES//CYTOKINE AUTOANTIBODIES//AUTOANTIBODIES TO CYTOKINES
9 22506 CARDIOTROPHIN 1//HSP 56//INTERLEUKIN 6 CYTOKINE FAMILY
10 2155 MULTIPLE MYELOMA//PLASMA CELL LEUKEMIA//MYELOMA

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