Class information for:
Level 1: FETAL HEMOGLOBIN//HEMOGLOBINOPATHY THALASSEMIA UNIT//GAMMA GLOBIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9383 1160 36.0 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
455 3       HEMOGLOBIN//SICKLE CELL DISEASE//SICKLE CELL ANEMIA 25359
1216 2             PU1//ETS 1//GATA 1 9149
9383 1                   FETAL HEMOGLOBIN//HEMOGLOBINOPATHY THALASSEMIA UNIT//GAMMA GLOBIN 1160

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FETAL HEMOGLOBIN authKW 1031387 9% 38% 104
2 HEMOGLOBINOPATHY THALASSEMIA UNIT address 475110 2% 95% 19
3 GAMMA GLOBIN authKW 430696 3% 55% 30
4 BCL11A authKW 250040 2% 50% 19
5 DEV PHARMACOL PHARMACOGENOM THER Y THALASS address 211819 1% 62% 13
6 HBF INDUCTION authKW 193822 1% 82% 9
7 ERYTHROID DIFFERENTIATION authKW 141904 3% 14% 39
8 FETAL HAEMOGLOBIN authKW 134581 1% 34% 15
9 HYDROXYUREA authKW 131979 6% 7% 74
10 HBS1L MYB authKW 131610 0% 100% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 41586 57% 0% 665
2 Medicine, Research & Experimental 918 11% 0% 133
3 Genetics & Heredity 331 8% 0% 97
4 Biochemistry & Molecular Biology 225 16% 0% 184
5 Cell Biology 149 8% 0% 91
6 Biology 95 3% 0% 38
7 CYTOLOGY & HISTOLOGY 78 0% 0% 5
8 Medicine, General & Internal 73 5% 0% 63
9 Pediatrics 60 4% 0% 41
10 Oncology 44 5% 0% 63

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HEMOGLOBINOPATHY THALASSEMIA UNIT 475110 2% 95% 19
2 DEV PHARMACOL PHARMACOGENOM THER Y THALASS 211819 1% 62% 13
3 GENTECH THAL 84229 0% 80% 4
4 MOL GENOM THER EUT SECT 82252 0% 63% 5
5 MOL MED BRANCH 64989 1% 15% 17
6 CELL GENE THER Y GRP 56094 1% 24% 9
7 AL OMRAN SCI CHAIR HEMATOL DIS 52644 0% 100% 2
8 DEV GENE PHARMACOGEN THER Y THALASSAEMIA 52644 0% 100% 2
9 MED PEDIAT PHARMACOL EXPT THER EUT 52644 0% 100% 2
10 TOHOKU MED MEGABANK 50613 0% 38% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BLOOD CELLS MOLECULES AND DISEASES 35570 4% 3% 49
2 HEMOGLOBIN 25785 4% 2% 47
3 BLOOD 21106 14% 0% 166
4 EXPERIMENTAL HEMATOLOGY 12910 5% 1% 53
5 AMERICAN JOURNAL OF HEMATOLOGY 8925 4% 1% 45
6 BRITISH JOURNAL OF HAEMATOLOGY 6509 5% 0% 58
7 MINERVA BIOTECNOLOGICA 3990 1% 2% 9
8 TEXAS REPORTS ON BIOLOGY AND MEDICINE 2937 0% 3% 4
9 ACTA HAEMATOLOGICA 2729 2% 1% 19
10 HAEMATOLOGICA 1831 1% 0% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FETAL HEMOGLOBIN 1031387 9% 38% 104 Search FETAL+HEMOGLOBIN Search FETAL+HEMOGLOBIN
2 GAMMA GLOBIN 430696 3% 55% 30 Search GAMMA+GLOBIN Search GAMMA+GLOBIN
3 BCL11A 250040 2% 50% 19 Search BCL11A Search BCL11A
4 HBF INDUCTION 193822 1% 82% 9 Search HBF+INDUCTION Search HBF+INDUCTION
5 ERYTHROID DIFFERENTIATION 141904 3% 14% 39 Search ERYTHROID+DIFFERENTIATION Search ERYTHROID+DIFFERENTIATION
6 FETAL HAEMOGLOBIN 134581 1% 34% 15 Search FETAL+HAEMOGLOBIN Search FETAL+HAEMOGLOBIN
7 HYDROXYUREA 131979 6% 7% 74 Search HYDROXYUREA Search HYDROXYUREA
8 HBS1L MYB 131610 0% 100% 5 Search HBS1L+MYB Search HBS1L+MYB
9 KLF1 GENE 109673 0% 83% 5 Search KLF1+GENE Search KLF1+GENE
10 FETAL HEMOGLOBIN HB F 107476 1% 58% 7 Search FETAL+HEMOGLOBIN+HB+F Search FETAL+HEMOGLOBIN+HB+F

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MUSALLAM, KM , TAHER, AT , CAPPELLINI, MD , SANKARAN, VG , (2013) CLINICAL EXPERIENCE WITH FETAL HEMOGLOBIN INDUCTION THERAPY IN PATIENTS WITH BETA-THALASSEMIA.BLOOD. VOL. 121. ISSUE 12. P. 2199-2212 78 74% 32
2 MABAERA, R , WEST, RJ , CONINE, SJ , LOWREY, CH , ENGMAN, CA , BOYD, CD , MACARI, ER , (2008) A CELL STRESS SIGNALING MODEL OF FETAL HEMOGLOBIN INDUCTION: WHAT DOESN'T KILL RED BLOOD CELLS MAY MAKE THEM STRONGER.EXPERIMENTAL HEMATOLOGY. VOL. 36. ISSUE 9. P. 1057-1072 93 67% 44
3 BANAN, M , (2013) HYDROXYUREA TREATMENT IN BETA-THALASSEMIA PATIENTS: TO RESPOND OR NOT TO RESPOND?.ANNALS OF HEMATOLOGY. VOL. 92. ISSUE 3. P. 289-299 61 69% 5
4 TESTA, U , (2009) FETAL HEMOGLOBIN CHEMICAL INDUCERS FOR TREATMENT OF HEMOGLOBINOPATHIES.ANNALS OF HEMATOLOGY. VOL. 88. ISSUE 6. P. 505-528 94 47% 23
5 PERRINE, SP , PACE, BS , FALLER, DV , (2014) TARGETED FETAL HEMOGLOBIN INDUCTION FOR TREATMENT OF BETA HEMOGLOBINOPATHIES.HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA. VOL. 28. ISSUE 2. P. 233-+ 51 72% 14
6 THEIN, SL , (2012) THE EMERGING ROLE OF FETAL HEMOGLOBIN INDUCTION IN NON-TRANSFUSION-DEPENDENT THALASSEMIA.BLOOD REVIEWS. VOL. 26. ISSUE . P. S35-S39 47 84% 11
7 SRIPICHAI, O , FUCHAROEN, S , (2016) FETAL HEMOGLOBIN REGULATION IN BETA-THALASSEMIA: HETEROGENEITY, MODIFIERS AND THERAPEUTIC APPROACHES.EXPERT REVIEW OF HEMATOLOGY. VOL. 9. ISSUE 12. P. 1129 -1137 60 63% 0
8 DAI, Y , SANGERMAN, J , LUO, HY , FUCHAROEN, S , CHUI, DHK , FALLER, DV , PERRINE, SP , (2016) THERAPEUTIC FETAL-GLOBIN INDUCERS REDUCE TRANSCRIPTIONAL REPRESSION IN HEMOGLOBINOPATHY ERYTHROID PROGENITORS THROUGH DISTINCT MECHANISMS.BLOOD CELLS MOLECULES AND DISEASES. VOL. 56. ISSUE 1. P. 62 -69 46 81% 0
9 GAMBARI, R , FIBACH, E , (2007) MEDICINAL CHEMISTRY OF FETAL HEMOGLOBIN INDUCERS FOR TREATMENT OF BETA-THALASSEMIA.CURRENT MEDICINAL CHEMISTRY. VOL. 14. ISSUE 2. P. 199-212 68 59% 17
10 SANKARAN, VG , ORKIN, SH , (2013) THE SWITCH FROM FETAL TO ADULT HEMOGLOBIN.COLD SPRING HARBOR PERSPECTIVES IN MEDICINE. VOL. 3. ISSUE 1. P. - 48 56% 40

Classes with closest relation at Level 1


Rank Class id link
1 7111 LOCUS CONTROL REGION//HEMOGLOBIN SWITCHING//EKLF
2 95 HEMOGLOBIN//ALPHA THALASSEMIA//BETA THALASSEMIA
3 7880 ERYTHROPOIETIN RECEPTOR//ERYTHROPOIESIS//ERYTHROBLASTIC ISLAND
4 34230 BCL11B//BCL11B GENE//BCL11A EXPRESSION
5 27142 B B RAT//CFU SD8//FITNESS1 LOCUS
6 103 SICKLE CELL DISEASE//SICKLE CELL ANEMIA//ACUTE CHEST SYNDROME
7 23337 MED SCI SLOAN KETTERING//MURINE ERYTHROLEUKEMIA//BENZIDINE POSITIVITY
8 13096 ANTISICKLING ACTIVITY//ANTISICKLING AGENTS THERAPEUTIC USE//ANTISICKLING
9 19183 INT TRANSPLANTAT THALASSEMIA SICKLE CELL AN//MEDITERRANEAN HEMATOL//TR IANTO MIDOLLO OSSEO MURAGLIA
10 14203 GATA 1//GATA2//EDAG

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