Class information for:
Level 1: LOCUS CONTROL REGION//HEMOGLOBIN SWITCHING//EKLF

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7111 1404 44.2 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
455 3       HEMOGLOBIN//SICKLE CELL DISEASE//SICKLE CELL ANEMIA 25359
1216 2             PU1//ETS 1//GATA 1 9149
7111 1                   LOCUS CONTROL REGION//HEMOGLOBIN SWITCHING//EKLF 1404

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LOCUS CONTROL REGION authKW 867503 5% 53% 75
2 HEMOGLOBIN SWITCHING authKW 198817 1% 57% 16
3 EKLF authKW 181213 1% 56% 15
4 GLOBIN GENES authKW 163724 2% 30% 25
5 LCR authKW 146753 2% 25% 27
6 NF E2 authKW 130914 1% 35% 17
7 HS 40 authKW 111841 0% 86% 6
8 BETA GLOBIN LOCUS authKW 96869 0% 64% 7
9 GLOBIN authKW 94515 3% 12% 36
10 ALTHOUSE 206 address 81964 0% 54% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 9236 66% 0% 923
2 Cell Biology 8049 39% 0% 548
3 Hematology 4041 17% 0% 237
4 Genetics & Heredity 1952 17% 0% 232
5 Developmental Biology 919 5% 0% 77
6 Biology 74 3% 0% 39
7 Biotechnology & Applied Microbiology 71 5% 0% 64
8 Biophysics 66 4% 0% 51
9 Medicine, Research & Experimental 45 3% 0% 47
10 Evolutionary Biology 3 1% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALTHOUSE 206 81964 0% 54% 7
2 BIOCHEM MOL BIOL ALTHOUSE 206 43494 0% 100% 2
3 PHARMACOLMED SCI 383 43494 0% 100% 2
4 STRUCT FUNCT ORG CHROMOSOMES 35510 0% 23% 7
5 HEMATOPOIESIS SECT 33221 1% 17% 9
6 MOL BIOL UNIT 7242 32618 0% 50% 3
7 MED SCI 385 28995 0% 67% 2
8 MOLEC BIOL UNIT 7242 28995 0% 67% 2
9 GENE BIOL 28153 2% 4% 35
10 ROTARY BONE MARROW 24456 0% 19% 6

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR AND CELLULAR BIOLOGY 20776 10% 1% 146
2 BLOOD 7983 8% 0% 113
3 NUCLEIC ACIDS RESEARCH 6669 8% 0% 111
4 BLOOD CELLS MOLECULES AND DISEASES 4870 1% 1% 20
5 GENES & DEVELOPMENT 3948 3% 0% 37
6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 3065 8% 0% 118
7 EMBO JOURNAL 2986 3% 0% 49
8 JOURNAL OF BIOLOGICAL CHEMISTRY 1625 8% 0% 111
9 GENOMICS 1236 2% 0% 22
10 CELL 1095 2% 0% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LOCUS CONTROL REGION 867503 5% 53% 75 Search LOCUS+CONTROL+REGION Search LOCUS+CONTROL+REGION
2 HEMOGLOBIN SWITCHING 198817 1% 57% 16 Search HEMOGLOBIN+SWITCHING Search HEMOGLOBIN+SWITCHING
3 EKLF 181213 1% 56% 15 Search EKLF Search EKLF
4 GLOBIN GENES 163724 2% 30% 25 Search GLOBIN+GENES Search GLOBIN+GENES
5 LCR 146753 2% 25% 27 Search LCR Search LCR
6 NF E2 130914 1% 35% 17 Search NF+E2 Search NF+E2
7 HS 40 111841 0% 86% 6 Search HS+40 Search HS+40
8 BETA GLOBIN LOCUS 96869 0% 64% 7 Search BETA+GLOBIN+LOCUS Search BETA+GLOBIN+LOCUS
9 GLOBIN 94515 3% 12% 36 Search GLOBIN Search GLOBIN
10 HUMAN EPSILON GLOBIN GENE 77666 0% 71% 5 Search HUMAN+EPSILON+GLOBIN+GENE Search HUMAN+EPSILON+GLOBIN+GENE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HARDISON, R , SLIGHTOM, JL , GUMUCIO, DL , GOODMAN, M , STOJANOVIC, N , MILLER, W , (1997) LOCUS CONTROL REGIONS OF MAMMALIAN BETA-GLOBIN GENE CLUSTERS: COMBINING PHYLOGENETIC ANALYSES AND EXPERIMENTAL RESULTS TO GAIN FUNCTIONAL INSIGHTS.GENE. VOL. 205. ISSUE 1-2. P. 73 -94 97 87% 162
2 PETERSON, KR , FEDOSYUK, H , HARJU-BAKER, S , (2012) LCR 5 ' HYPERSENSITIVE SITE SPECIFICITY FOR GLOBIN GENE ACTIVATION WITHIN THE ACTIVE CHROMATIN HUB.NUCLEIC ACIDS RESEARCH. VOL. 40. ISSUE 22. P. 11256-11269 55 100% 1
3 PALSTRA, RJ , DE LAAT, W , GROSVELD, F , (2008) BETA-GLOBIN REGULATION AND LONG-RANGE INTERACTIONS.LONG-RANGE CONTROL OF GENE EXPRESSION. VOL. 61. ISSUE . P. 107-142 90 54% 74
4 HARJU, S , MCQUEEN, KJ , PETERSON, KR , (2002) CHROMATIN STRUCTURE AND CONTROL OF BETA-LIKE GLOBIN GENE SWITCHING.EXPERIMENTAL BIOLOGY AND MEDICINE. VOL. 227. ISSUE 9. P. 683-700 97 61% 37
5 RAZIN, SV , FARRELL, CM , RECILLAS-TARGA, F , (2003) GENOMIC DOMAINS AND REGULATORY ELEMENTS OPERATING AT THE DOMAIN LEVEL.INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 226. VOL. 226. ISSUE . P. 63-125 120 48% 27
6 FEDOSYUK, H , PETERSON, KR , (2007) DELETION OF THE HUMAN BETA-GLOBIN LCR 5 ' HS4 OR 5 ' HS1 DIFFERENTIALLY AFFECTS BETA-LIKE GLOBIN GENE EXPRESSION IN BETA-YAC TRANSGENIC MICE.BLOOD CELLS MOLECULES AND DISEASES. VOL. 39. ISSUE 1. P. 44-55 53 95% 7
7 BRESNICK, EH , JOHNSON, KD , KIM, SI , IM, H , (2006) ESTABLISHMENT AND REGULATION OF CHROMATIN DOMAINS: MECHANISTIC INSIGHTS FROM STUDIES OF HEMOGLOBIN SYNTHESIS.PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 81. VOL. 81. ISSUE . P. 435 -471 99 51% 9
8 FANG, XD , SUN, J , XIANG, P , YU, M , NAVAS, PA , PETERSON, KR , STAMATOYANNOPOULOS, G , LI, QL , (2005) SYNERGISTIC AND ADDITIVE PROPERTIES OF THE BETA-GLOBIN LOCUS CONTROL REGION (LCR) REVEALED BY 5 ' HS3 DELETION MUTATIONS: IMPLICATION FOR LCR CHROMATIN ARCHITECTURE.MOLECULAR AND CELLULAR BIOLOGY. VOL. 25. ISSUE 16. P. 7033-7041 55 90% 19
9 LI, QL , PETERSON, KR , FANG, XD , STAMATOYANNOPOULOS, G , (2002) LOCUS CONTROL REGIONS.BLOOD. VOL. 100. ISSUE 9. P. 3077-3086 73 54% 235
10 RAZIN, SV , ULIANOV, SV , IOUDINKOVA, ES , GUSHCHANSKAYA, ES , GAVRILOV, AA , IAROVAIA, OV , (2012) DOMAINS OF ALPHA- AND BETA-GLOBIN GENES IN THE CONTEXT OF THE STRUCTURAL-FUNCTIONAL ORGANIZATION OF THE EUKARYOTIC GENOME.BIOCHEMISTRY-MOSCOW. VOL. 77. ISSUE 13. P. 1409-1423 66 60% 1

Classes with closest relation at Level 1


Rank Class id link
1 14203 GATA 1//GATA2//EDAG
2 9383 FETAL HEMOGLOBIN//HEMOGLOBINOPATHY THALASSEMIA UNIT//GAMMA GLOBIN
3 27051 MAFB//C MAF//EXPT THER EUT TRANSLAT ONCOL PROGRAM
4 11594 CTCF//CONTROL GENET PROC//SUHW
5 23337 MED SCI SLOAN KETTERING//MURINE ERYTHROLEUKEMIA//BENZIDINE POSITIVITY
6 27142 B B RAT//CFU SD8//FITNESS1 LOCUS
7 30859 GRHL2//GRAINYHEAD//LATE SV40 FACTOR
8 20513 CHICKEN LYSOZYME GENE//MACROPHAGE SPECIFIC GENE EXPRESSION//ANAEROBIC RESPONSE ELEMENT
9 95 HEMOGLOBIN//ALPHA THALASSEMIA//BETA THALASSEMIA
10 23176 COMPARATIVE DETERMINANT ANALYSIS//ABT IMMUNOGENET//AND MACROEVOLUTION

Go to start page