Class information for:
Level 1: PHENYLALANINE HYDROXYLASE//AROMATIC AMINO ACID HYDROXYLASE//TRYPTOPHAN HYDROXYLASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9156 1182 38.8 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
124 3       PARKINSONS DISEASE//MOVEMENT DISORDERS//DEEP BRAIN STIMULATION 67777
2411 2             PHENYLKETONURIA//PHENYLALANINE HYDROXYLASE//PKU 4184
9156 1                   PHENYLALANINE HYDROXYLASE//AROMATIC AMINO ACID HYDROXYLASE//TRYPTOPHAN HYDROXYLASE 1182

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHENYLALANINE HYDROXYLASE authKW 435330 5% 26% 64
2 AROMATIC AMINO ACID HYDROXYLASE authKW 281276 1% 78% 14
3 TRYPTOPHAN HYDROXYLASE authKW 281208 6% 15% 72
4 TYROSINE HYDROXYLASE authKW 238596 15% 5% 176
5 INSECT BRAIN NEUROBIOL address 82661 0% 80% 4
6 SEROTONIN BIOSYNTHESIS authKW 58704 0% 45% 5
7 DOPAMINE INHIBITION authKW 58121 0% 75% 3
8 NEUROCATIN authKW 58121 0% 75% 3
9 TYROSINE HYDROXYLASE GENE authKW 55024 1% 30% 7
10 AUTOREGULATORY SEQUENCE authKW 51664 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 7972 66% 0% 786
2 Neurosciences 2882 30% 0% 354
3 Biophysics 999 11% 0% 135
4 Biochemical Research Methods 139 5% 0% 54
5 Pharmacology & Pharmacy 93 8% 0% 93
6 Cell Biology 35 5% 0% 59
7 Biology 16 2% 0% 21
8 Genetics & Heredity 9 3% 0% 32
9 Medicine, Research & Experimental 6 2% 0% 25
10 Chemistry, Analytical 3 2% 0% 28

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INSECT BRAIN NEUROBIOL 82661 0% 80% 4
2 LSUHSC BIOCHEM 51664 0% 100% 2
3 BIOL MOIL SEVERO OCHOA 25832 0% 100% 1
4 BIOMOL NEUROSCI 25832 0% 100% 1
5 CAVANILLES BIO ERAITAT BIOL EVOLUT 25832 0% 100% 1
6 DEPARMENT AQUACULTURE 25832 0% 100% 1
7 ECOL MICROBIENNEUMR5557 25832 0% 100% 1
8 EQUIPE INTERACT CELLULAI MOL REPROD 25832 0% 100% 1
9 GENET MOL NEUROTRANSMISS PROC NEURODIGENERA 25832 0% 100% 1
10 GENET MOL NEUROTRANSMISS PROC NEUROGENERAT 25832 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NEUROCHEMISTRY 22583 11% 1% 135
2 PTERIDINES 7715 1% 3% 11
3 NEUROCHEMISTRY INTERNATIONAL 5565 3% 1% 34
4 BIOCHEMISTRY 2854 7% 0% 78
5 BIOGENIC AMINES 2675 1% 1% 9
6 JOURNAL OF BIOLOGICAL CHEMISTRY 1716 9% 0% 104
7 BIOCHEMICAL JOURNAL 1289 3% 0% 39
8 NEUROCHEMICAL RESEARCH 1120 2% 0% 18
9 EUROPEAN JOURNAL OF BIOCHEMISTRY 981 2% 0% 28
10 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 836 2% 0% 24

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PHENYLALANINE HYDROXYLASE 435330 5% 26% 64 Search PHENYLALANINE+HYDROXYLASE Search PHENYLALANINE+HYDROXYLASE
2 AROMATIC AMINO ACID HYDROXYLASE 281276 1% 78% 14 Search AROMATIC+AMINO+ACID+HYDROXYLASE Search AROMATIC+AMINO+ACID+HYDROXYLASE
3 TRYPTOPHAN HYDROXYLASE 281208 6% 15% 72 Search TRYPTOPHAN+HYDROXYLASE Search TRYPTOPHAN+HYDROXYLASE
4 TYROSINE HYDROXYLASE 238596 15% 5% 176 Search TYROSINE+HYDROXYLASE Search TYROSINE+HYDROXYLASE
5 SEROTONIN BIOSYNTHESIS 58704 0% 45% 5 Search SEROTONIN+BIOSYNTHESIS Search SEROTONIN+BIOSYNTHESIS
6 DOPAMINE INHIBITION 58121 0% 75% 3 Search DOPAMINE+INHIBITION Search DOPAMINE+INHIBITION
7 NEUROCATIN 58121 0% 75% 3 Search NEUROCATIN Search NEUROCATIN
8 TYROSINE HYDROXYLASE GENE 55024 1% 30% 7 Search TYROSINE+HYDROXYLASE+GENE Search TYROSINE+HYDROXYLASE+GENE
9 AUTOREGULATORY SEQUENCE 51664 0% 100% 2 Search AUTOREGULATORY+SEQUENCE Search AUTOREGULATORY+SEQUENCE
10 HUMAN TYROSINE HYDROXYLASE TYPE 1 51664 0% 100% 2 Search HUMAN+TYROSINE+HYDROXYLASE+TYPE+1 Search HUMAN+TYROSINE+HYDROXYLASE+TYPE+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TEKIN, I , ROSKOSKI, R , CARKACI-SALLI, N , VRANA, KE , (2014) COMPLEX MOLECULAR REGULATION OF TYROSINE HYDROXYLASE.JOURNAL OF NEURAL TRANSMISSION. VOL. 121. ISSUE 12. P. 1451 -1481 160 59% 8
2 FITZPATRICK, PF , (1999) TETRAHYDROPTERIN-DEPENDENT AMINO ACID HYDROXYLASES.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 68. ISSUE . P. 355 -381 112 90% 282
3 KAPPOCK, TJ , CARADONNA, JP , (1996) PTERIN-DEPENDENT AMINO ACID HYDROXYLASES.CHEMICAL REVIEWS. VOL. 96. ISSUE 7. P. 2659 -2756 233 47% 229
4 DICKSON, PW , VON NAGY-FELSOBUKI, EI , GRAHAM, ME , BOBROVSKAYA, L , DUNKLEY, PR , (2004) TYROSINE HYDROXYLASE PHOSPHORYLATION: REGULATION AND CONSEQUENCES.JOURNAL OF NEUROCHEMISTRY. VOL. 91. ISSUE 5. P. 1025-1043 94 87% 249
5 FITZPATRICK, PF , (2000) THE AROMATIC AMINO ACID HYDROXYLASES.ADVANCES IN ENZYMOLOGY, VOL 74. VOL. 74. ISSUE . P. 235 -+ 125 79% 59
6 FITZPATRICK, PF , (2012) ALLOSTERIC REGULATION OF PHENYLALANINE HYDROXYLASE.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 519. ISSUE 2. P. 194-201 76 90% 23
7 HUFTON, SE , JENNINGS, IG , COTTON, RGH , (1995) STRUCTURE AND FUNCTION OF THE AROMATIC AMINO-ACID HYDROXYLASES.BIOCHEMICAL JOURNAL. VOL. 311. ISSUE . P. 353 -366 127 80% 151
8 KUMER, SC , VRANA, KE , (1996) INTRICATE REGULATION OF TYROSINE HYDROXYLASE ACTIVITY AND GENE EXPRESSION.JOURNAL OF NEUROCHEMISTRY. VOL. 67. ISSUE 2. P. 443 -462 106 58% 514
9 WANG, SZ , SURA, GR , DANGOTT, LJ , FITZPATRICK, PF , (2009) IDENTIFICATION BY HYDROGEN/DEUTERIUM EXCHANGE OF STRUCTURAL CHANGES IN TYROSINE HYDROXYLASE ASSOCIATED WITH REGULATION.BIOCHEMISTRY. VOL. 48. ISSUE 22. P. 4972-4979 51 91% 6
10 OLSSON, E , TEIGEN, K , MARTINEZ, A , JENSEN, VR , (2010) THE AROMATIC AMINO ACID HYDROXYLASE MECHANISM: A PERSPECTIVE FROM COMPUTATIONAL CHEMISTRY.ADVANCES IN INORGANIC CHEMISTRY: THEORETICAL AND COMPUTATIONAL INORGANIC CHEMISTRY, VOL 62. VOL. 62. ISSUE . P. 437-500 72 55% 5

Classes with closest relation at Level 1


Rank Class id link
1 16385 PHENYLETHANOLAMINE N METHYLTRANSFERASE//TYROSINE HYDROXYLASE//PNMT
2 4393 TETRAHYDROBIOPTERIN//GTP CYCLOHYDROLASE I//SEPIAPTERIN REDUCTASE
3 2133 PHENYLKETONURIA//PKU//HYPERPHENYLALANINEMIA
4 18043 DOPA RESPONSIVE DYSTONIA//CEREBRAL FOLATE DEFICIENCY//SEGAWA DISEASE
5 34423 DOPAMINE SYNTHESIS IN BRAIN//FLUORESCENCE MICROPHOTOMETRY//FLUORESCENCE MICROPHOTOMETRY SYSTEM
6 8678 TPH2//TRYPTOPHAN HYDROXYLASE 2//TRYPTOPHAN HYDROXYLASE
7 7108 CHROMAFFIN CELLS//CATECHOLAMINE SECRETION//CATECHOLAMINE RELEASE
8 19073 AROMATIC L AMINO ACID DECARBOXYLASE//L DOPA DECARBOXYLASE//DOPA DECARBOXYLASE
9 24601 PUSH PULL SUPERFUSION//PUSH PULL CANNULA//RU24722
10 35671 CANDU//FUNCTIONAL UNITS OF PROTEINS//HOP PURPAN MED BIOCHIM MED

Go to start page