Class information for:
Level 1: TPH2//TRYPTOPHAN HYDROXYLASE 2//TRYPTOPHAN HYDROXYLASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8678 1229 48.2 74%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
76 3       NEUROSCIENCES//DOPAMINE//SEROTONIN 81359
446 2             AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS//5 HTTLPR//PSYCHIATRIC GENETICS 16189
8678 1                   TPH2//TRYPTOPHAN HYDROXYLASE 2//TRYPTOPHAN HYDROXYLASE 1229

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TPH2 authKW 896366 5% 57% 63
2 TRYPTOPHAN HYDROXYLASE 2 authKW 542337 3% 53% 41
3 TRYPTOPHAN HYDROXYLASE authKW 394910 7% 18% 87
4 SUICIDE authKW 254448 23% 4% 287
5 MCGILL GRP SUICIDE STUDIES address 185158 3% 17% 43
6 TRYPTOPHAN HYDROXYLASE GENE authKW 167693 1% 75% 9
7 SUICIDAL BEHAVIOR authKW 159125 4% 12% 54
8 C1473G POLYMORPHISM authKW 149064 0% 100% 6
9 HUMAN ECOL HLTH ORG address 149064 0% 100% 6
10 TPH1 authKW 127216 1% 39% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Psychiatry 42658 66% 0% 816
2 Neurosciences 5077 38% 0% 468
3 Clinical Neurology 1273 15% 0% 187
4 Genetics & Heredity 442 9% 0% 113
5 Psychology 429 5% 0% 56
6 Pharmacology & Pharmacy 384 13% 0% 156
7 Psychology, Multidisciplinary 365 4% 0% 54
8 Behavioral Sciences 237 4% 0% 44
9 Psychology, Clinical 139 3% 0% 35
10 Substance Abuse 101 2% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MCGILL GRP SUICIDE STUDIES 185158 3% 17% 43
2 HUMAN ECOL HLTH ORG 149064 0% 100% 6
3 MOL IMAGING NEUROPATHOL 55410 2% 9% 25
4 ADV BIOMED IT CORE 49688 0% 100% 2
5 NEUROCIENCIAS GENET MOL 49688 0% 100% 2
6 MULTIDISCIPLINARIA COMALCALCO 38768 1% 20% 8
7 INVEST GENOM 33124 0% 67% 2
8 MED SCI ENVIRONM HLTH SAFETY 33124 0% 67% 2
9 WUXI PSYCHIAT HOSP 33124 0% 67% 2
10 NEUROCHEM MOL NEUROBIOL 31163 1% 16% 8

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 22754 3% 2% 41
2 ARCHIVES OF SUICIDE RESEARCH 17437 1% 4% 17
3 MOLECULAR PSYCHIATRY 17425 3% 2% 40
4 PSYCHIATRIC GENETICS 13347 2% 2% 22
5 PSYCHIATRY RESEARCH 10281 5% 1% 57
6 BIOLOGICAL PSYCHIATRY 9500 5% 1% 59
7 JOURNAL OF AFFECTIVE DISORDERS 8634 4% 1% 54
8 SUICIDE AND LIFE-THREATENING BEHAVIOR 7124 2% 1% 21
9 NEUROPSYCHOBIOLOGY 6502 2% 1% 25
10 ARCHIVES OF GENERAL PSYCHIATRY 6462 3% 1% 32

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TPH2 896366 5% 57% 63 Search TPH2 Search TPH2
2 TRYPTOPHAN HYDROXYLASE 2 542337 3% 53% 41 Search TRYPTOPHAN+HYDROXYLASE+2 Search TRYPTOPHAN+HYDROXYLASE+2
3 TRYPTOPHAN HYDROXYLASE 394910 7% 18% 87 Search TRYPTOPHAN+HYDROXYLASE Search TRYPTOPHAN+HYDROXYLASE
4 SUICIDE 254448 23% 4% 287 Search SUICIDE Search SUICIDE
5 TRYPTOPHAN HYDROXYLASE GENE 167693 1% 75% 9 Search TRYPTOPHAN+HYDROXYLASE+GENE Search TRYPTOPHAN+HYDROXYLASE+GENE
6 SUICIDAL BEHAVIOR 159125 4% 12% 54 Search SUICIDAL+BEHAVIOR Search SUICIDAL+BEHAVIOR
7 C1473G POLYMORPHISM 149064 0% 100% 6 Search C1473G+POLYMORPHISM Search C1473G+POLYMORPHISM
8 TPH1 127216 1% 39% 13 Search TPH1 Search TPH1
9 CSF 5 HIAA 111789 1% 50% 9 Search CSF+5+HIAA Search CSF+5+HIAA
10 FAMILY HISTORY OF SUICIDE 103515 0% 83% 5 Search FAMILY+HISTORY+OF+SUICIDE Search FAMILY+HISTORY+OF+SUICIDE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ANTYPA, N , SERRETTI, A , RUJESCU, D , (2013) SEROTONERGIC GENES AND SUICIDE: A SYSTEMATIC REVIEW.EUROPEAN NEUROPSYCHOPHARMACOLOGY. VOL. 23. ISSUE 10. P. 1125-1142 105 69% 29
2 GERARDIN, P , COHEN, D , MIRKOVIC, B , LAURENT, C , PODLIPSKI, MA , FREBOURG, T , (2016) GENETIC ASSOCIATION STUDIES OF SUICIDAL BEHAVIOR: A REVIEW OF THE PAST 10 YEARS, PROGRESS, LIMITATIONS, AND FUTURE DIRECTIONS.FRONTIERS IN PSYCHIATRY. VOL. 7. ISSUE . P. - 91 58% 1
3 BREZO, J , KLEMPAN, T , TURECKI, G , (2008) THE GENETICS OF SUICIDE: A CRITICAL REVIEW OF MOLECULAR STUDIES.PSYCHIATRIC CLINICS OF NORTH AMERICA. VOL. 31. ISSUE 2. P. 179 -+ 100 56% 53
4 BONDY, B , BUETTNER, A , ZILL, P , (2006) GENETICS OF SUICIDE.MOLECULAR PSYCHIATRY. VOL. 11. ISSUE 4. P. 336 -351 92 51% 157
5 GONZALEZ-CASTRO, TB , JUAREZ-ROJOP, I , LOPEZ-NARVAEZ, ML , TOVILLA-ZARATE, CA , (2014) ASSOCIATION OF TPH-1 AND TPH-2 GENE POLYMORPHISMS WITH SUICIDAL BEHAVIOR: A SYSTEMATIC REVIEW AND META-ANALYSIS.BMC PSYCHIATRY. VOL. 14. ISSUE . P. - 52 88% 7
6 STEFULJ, J , BORDUKALO-NIKSIC, T , (2010) NEURONAL TRYPTOPHAN HYDROXYLASE (TPH2) IN SUICIDAL BEHAVIOUR.TRANSLATIONAL NEUROSCIENCE. VOL. 1. ISSUE 3. P. 207-213 53 90% 0
7 CHEN, GL , MILLER, GM , (2012) ADVANCES IN TRYPTOPHAN HYDROXYLASE-2 GENE EXPRESSION REGULATION: NEW INSIGHTS INTO SEROTONIN-STRESS INTERACTION AND CLINICAL IMPLICATIONS.AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. VOL. 159B. ISSUE 2. P. 152 -171 88 41% 22
8 LOPEZ-NARVAEZ, ML , TOVILLA-ZARATE, CA , GONZALEZ-CASTRO, TB , JUAREZ-ROJOP, I , POOL-GARCIA, S , GENIS, A , BLE-CASTILLO, JL , FRESAN, A , (2015) ASSOCIATION ANALYSIS OF TPH-1 AND TPH-2 GENES WITH SUICIDAL BEHAVIOR IN PATIENTS WITH ATTEMPTED SUICIDE IN MEXICAN POPULATION.COMPREHENSIVE PSYCHIATRY. VOL. 61. ISSUE . P. 72 -77 34 94% 0
9 LI, DW , HE, L , (2006) FURTHER CLARIFICATION OF THE CONTRIBUTION OF THE TRYPTOPHAN HYDROXYLASE (TPH) GENE TO SUICIDAL BEHAVIOR USING SYSTEMATIC ALLELIC AND GENOTYPIC META-ANALYSES.HUMAN GENETICS. VOL. 119. ISSUE 3. P. 233-240 39 91% 58
10 SOKOLOWSKI, M , WASSERMAN, J , WASSERMAN, D , (2015) AN OVERVIEW OF THE NEUROBIOLOGY OF SUICIDAL BEHAVIORS AS ONE META-SYSTEM.MOLECULAR PSYCHIATRY. VOL. 20. ISSUE 1. P. 56 -71 89 34% 2

Classes with closest relation at Level 1


Rank Class id link
1 3903 5 HTTLPR//SEROTONIN TRANSPORTER//SEROTONIN TRANSPORTER GENE
2 20072 MAOA//MONOAMINE OXIDASE A//MAOA GENE
3 19923 HLTH FAMILY STUDIES//CHOLESTEROL//ALICIA KOPLOWITZ FDN FELLOWSHIP
4 7438 H 3 IMIPRAMINE BINDING//H 3 PAROXETINE BINDING//IMIPRAMINE BINDING
5 10808 D FENFLURAMINE//FENFLURAMINE//PROLACTIN
6 14325 TRYPTOPHAN DEPLETION//ACUTE TRYPTOPHAN DEPLETION//TYROSINE DEPLETION
7 12432 DRD3//TARDIVE DYSKINESIA//HTR2A
8 672 SUICIDE//ATTEMPTED SUICIDE//SUICIDE ATTEMPT
9 35138 INTERMITTENT EXPLOSIVE DISORDER//CLIN NEUROSCI PSYCHOPHARMACOL UNIT//MIED
10 20371 MHPG//PLASMA MHPG//SALIVA MHPG

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